-
1
-
-
0029040619
-
Tissue type plasminogen activator-induced invasion and metastasis of murine melanomas
-
Alizadeh H, Ma D, Berman M, Bellingham D, Comerford SA, Gething MH, Sambrook JF and Niederkorn JY (1995) Tissue type plasminogen activator-induced invasion and metastasis of murine melanomas. Curr Eye Res 14: 449-458
-
(1995)
Curr Eye Res
, vol.14
, pp. 449-458
-
-
Alizadeh, H.1
Ma, D.2
Berman, M.3
Bellingham, D.4
Comerford, S.A.5
Gething, M.H.6
Sambrook, J.F.7
Niederkorn, J.Y.8
-
2
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis: A review
-
Andreasen PA, Kjoller L, Christensen L and Duffy MJ (1997) The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72: 1-22
-
(1997)
Int J Cancer
, vol.72
, pp. 1-22
-
-
Andreasen, P.A.1
Kjoller, L.2
Christensen, L.3
Duffy, M.J.4
-
3
-
-
0031902286
-
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
-
Bajou K, Noel A, Gerard RD, Masson V, Brunner N, Holst-Hansen C, Skobe M, Fusening NE, Carmeliet P, Tollen D and Foidart JM (1998) Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med 4: 923-928
-
(1998)
Nat Med
, vol.4
, pp. 923-928
-
-
Bajou, K.1
Noel, A.2
Gerard, R.D.3
Masson, V.4
Brunner, N.5
Holst-Hansen, C.6
Skobe, M.7
Fusening, N.E.8
Carmeliet, P.9
Tollen, D.10
Foidart, J.M.11
-
4
-
-
0028058264
-
Plasminogen activators and plasminogen activator inhibitor 1 in urinary tract cancer
-
Bashar H, Urano T, Pietrazek MH, Hata M, Suzuki K, Kawabe, K, Takada Y and Takada A (1994) Plasminogen activators and plasminogen activator inhibitor 1 in urinary tract cancer. Urol Int 52: 4-8
-
(1994)
Urol Int
, vol.52
, pp. 4-8
-
-
Bashar, H.1
Urano, T.2
Pietrazek, M.H.3
Hata, M.4
Suzuki, K.5
Kawabe, K.6
Takada, Y.7
Takada, A.8
-
5
-
-
0025130717
-
Plasminogen activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells
-
Cajot JF, Bamat J, Bergonzelli GE, Kruithof EKO, Medcalf RL and Testuz J (1990) Plasminogen activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells. Proc Natl Acad Sci USA 87: 6939-6943
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6939-6943
-
-
Cajot, J.F.1
Bamat, J.2
Bergonzelli, G.E.3
Kruithof, E.K.O.4
Medcalf, R.L.5
Testuz, J.6
-
6
-
-
0028077218
-
Plasminogen activators and plasminogen activator inhibitors in blood and tumor fluids of patients with ovarian cancer
-
Casslen B, Bossmar T, Lecander I and Astedt B (1994) Plasminogen activators and plasminogen activator inhibitors in blood and tumor fluids of patients with ovarian cancer. Eur J Cancer 30: 1302-1309
-
(1994)
Eur J Cancer
, vol.30
, pp. 1302-1309
-
-
Casslen, B.1
Bossmar, T.2
Lecander, I.3
Astedt, B.4
-
7
-
-
0021780949
-
Plasminogen activators, tissue degradation, and cancer
-
Dano K, Andreasen PA, Grondahl-Hansen J, Kristensen P, Nielsen LS and Skriver L (1985) Plasminogen activators, tissue degradation, and cancer. Adv Cancer Res 44: 139-266
-
(1985)
Adv Cancer Res
, vol.44
, pp. 139-266
-
-
Dano, K.1
Andreasen, P.A.2
Grondahl-Hansen, J.3
Kristensen, P.4
Nielsen, L.S.5
Skriver, L.6
-
8
-
-
0031031869
-
Neutralization of plasminogen activator inhihitor-1 inhibitory properties: Identification of two different mechanisms
-
Debrock S and Declerck PJ (1997) Neutralization of plasminogen activator inhihitor-1 inhibitory properties: identification of two different mechanisms. Biochim Biophys Acta 1337: 257-266
-
(1997)
Biochim Biophys Acta
, vol.1337
, pp. 257-266
-
-
Debrock, S.1
Declerck, P.J.2
-
9
-
-
0029816265
-
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
-
Deng G, Curriden SA, Wang S, Rosenberg S and Loskutoff DJ (1996) Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J Cell Biol 134: 1563-1571
-
(1996)
J Cell Biol
, vol.134
, pp. 1563-1571
-
-
Deng, G.1
Curriden, S.A.2
Wang, S.3
Rosenberg, S.4
Loskutoff, D.J.5
-
10
-
-
0030841490
-
Type-1 plasminogen-activator inhibitor: Conformational differences between latent, active, reactive-centre-cleaved and plasminogen-activator-complexed forms, as probed by proteolytic susceptibility
-
Egelund R, Schousboe SL, Sottrup-Jensen L. Rodenburg KW and Andreasen PA (1997) Type-1 plasminogen-activator inhibitor: conformational differences between latent, active, reactive-centre-cleaved and plasminogen-activator-complexed forms, as probed by proteolytic susceptibility. Eur J Biochem 248: 775-785
-
(1997)
Eur J Biochem
, vol.248
, pp. 775-785
-
-
Egelund, R.1
Schousboe, S.L.2
Sottrup-Jensen, L.3
Rodenburg, K.W.4
Andreasen, P.A.5
-
11
-
-
0028048915
-
Plasminogen activator inhibitor-1 and prognosis in primary breast cancer
-
Fockens JA, Schmitt M, van Putten WL, Peters HA, Kramer MD, Janicke F and Klijn JG (1993) Plasminogen activator inhibitor-1 and prognosis in primary breast cancer. J Clin Oncol 12: 1648-1658
-
(1993)
J Clin Oncol
, vol.12
, pp. 1648-1658
-
-
Fockens, J.A.1
Schmitt, M.2
Van Putten, W.L.3
Peters, H.A.4
Kramer, M.D.5
Janicke, F.6
Klijn, J.G.7
-
12
-
-
0029943026
-
Substrate behavior of plasminogen activator inhibitor-1 is not associated with a lack of insertion of the reactive site loop
-
Gils A, Knockaert I and Declerck PJ (1996) Substrate behavior of plasminogen activator inhibitor-1 is not associated with a lack of insertion of the reactive site loop. Biochem 35: 7474-7481
-
(1996)
Biochem
, vol.35
, pp. 7474-7481
-
-
Gils, A.1
Knockaert, I.2
Declerck, P.J.3
-
13
-
-
0027223048
-
High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis
-
Grondahl-Hansen J, Christensen IJ, Rosenquist C, Brunner N, Mouridsen HT, Dano K and Blichert-Toft M (1993) High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis. Cancer Res 53: 2513-2521
-
(1993)
Cancer Res
, vol.53
, pp. 2513-2521
-
-
Grondahl-Hansen, J.1
Christensen, I.J.2
Rosenquist, C.3
Brunner, N.4
Mouridsen, H.T.5
Dano, K.6
Blichert-Toft, M.7
-
14
-
-
0029898212
-
Clinical relevance of urokinase plasminogen activator, its receptor, and its inhibitor in patients with renal cell carcinoma
-
Hofmann R, Lehmer A, Buresch M, Hartung R and Ulm K (1996) Clinical relevance of urokinase plasminogen activator, its receptor, and its inhibitor in patients with renal cell carcinoma. Cancer 78: 487-492
-
(1996)
Cancer
, vol.78
, pp. 487-492
-
-
Hofmann, R.1
Lehmer, A.2
Buresch, M.3
Hartung, R.4
Ulm, K.5
-
15
-
-
0027082979
-
Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer
-
Janicke F, Schmitt M, Pache L, Ulm K, Harbeck N. Hofler H and Graeff H (1993) Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer. Breast Cancer Res Treat 24: 195-208
-
(1993)
Breast Cancer Res Treat
, vol.24
, pp. 195-208
-
-
Janicke, F.1
Schmitt, M.2
Pache, L.3
Ulm, K.4
Harbeck, N.5
Hofler, H.6
Graeff, H.7
-
16
-
-
0029873910
-
The urokinase receptor is a major vitronectin binding protein on endothelial cells
-
Kanse SM, Kost C, Wilhelm OG, Andreasen PA and Preissner KT (1996) The urokinase receptor is a major vitronectin binding protein on endothelial cells. Exp Cell Res 224: 344-353
-
(1996)
Exp Cell Res
, vol.224
, pp. 344-353
-
-
Kanse, S.M.1
Kost, C.2
Wilhelm, O.G.3
Andreasen, P.A.4
Preissner, K.T.5
-
17
-
-
0000124642
-
Plasminogen activator inhibitor-1 represses integrin-and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation
-
Kjoller L, Kanse SM, Kirkegaard T, Rodenburg KW, Ronne E, Goodman SL, Preissner KT, Ossowski L and Andreasen PA (1997) Plasminogen activator inhibitor-1 represses integrin-and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation. Exp Cell Res 232: 420-429
-
(1997)
Exp Cell Res
, vol.232
, pp. 420-429
-
-
Kjoller, L.1
Kanse, S.M.2
Kirkegaard, T.3
Rodenburg, K.W.4
Ronne, E.5
Goodman, S.L.6
Preissner, K.T.7
Ossowski, L.8
Andreasen, P.A.9
-
18
-
-
0028639208
-
Impact of urokinase-type plasminogen activator and its inhibitor type I on prognosis in cervical cancer of the uterus
-
Kobayashi H, Fujishiro S and Terao T (1994) Impact of urokinase-type plasminogen activator and its inhibitor type I on prognosis in cervical cancer of the uterus. Cancer Res 54: 6539-6548
-
(1994)
Cancer Res
, vol.54
, pp. 6539-6548
-
-
Kobayashi, H.1
Fujishiro, S.2
Terao, T.3
-
19
-
-
0028656476
-
Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy
-
Kuhn W, Pache L, Schmalfeldt B, Dettmar P, Schmitt M, Janicke F and Graeff H (1994) Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy. Gynecol Oncol 55: 401-409
-
(1994)
Gynecol Oncol
, vol.55
, pp. 401-409
-
-
Kuhn, W.1
Pache, L.2
Schmalfeldt, B.3
Dettmar, P.4
Schmitt, M.5
Janicke, F.6
Graeff, H.7
-
20
-
-
0026462546
-
The plasminogen-plasmin system in malignancy
-
Kwaan HC (1992) The plasminogen-plasmin system in malignancy. Cancer Metast Res 11: 291-311
-
(1992)
Cancer Metast Res
, vol.11
, pp. 291-311
-
-
Kwaan, H.C.1
-
21
-
-
0031835192
-
Oestradiol regulation of the components of the plasminogen-plasmin system in MDA-MB-231 human breast cancer cells stably expressing the oestrogen receptor
-
Levenson AS, Kwaan HC, Svoboda KM, Weiss IM, Sakurai S and Jordan VC (1998) Oestradiol regulation of the components of the plasminogen-plasmin system in MDA-MB-231 human breast cancer cells stably expressing the oestrogen receptor. Br J Cancer 78: 88-95
-
(1998)
Br J Cancer
, vol.78
, pp. 88-95
-
-
Levenson, A.S.1
Kwaan, H.C.2
Svoboda, K.M.3
Weiss, I.M.4
Sakurai, S.5
Jordan, V.C.6
-
22
-
-
23444452203
-
Tumour-associated proteolytic factors uPA and PAI-1 and survival in totally resected gastric cancer
-
Nekarda H, Siewert JR, Schmitt M and Ulm K (1994) Tumour-associated proteolytic factors uPA and PAI-1 and survival in totally resected gastric cancer. Lancet 343: 117
-
(1994)
Lancet
, vol.343
, pp. 117
-
-
Nekarda, H.1
Siewert, J.R.2
Schmitt, M.3
Ulm, K.4
-
23
-
-
0028144441
-
Urokinase and plasminogen activator inhibitor type 1 in pulmonary adenocarcinoma
-
Pedersen H, Grondahl-Hansen J, Francis D, Osterlind K, Hansen HH, Dano K and Brunner N (1994) Urokinase and plasminogen activator inhibitor type 1 in pulmonary adenocarcinoma. Cancer Res 54: 120-123
-
(1994)
Cancer Res
, vol.54
, pp. 120-123
-
-
Pedersen, H.1
Grondahl-Hansen, J.2
Francis, D.3
Osterlind, K.4
Hansen, H.H.5
Dano, K.6
Brunner, N.7
-
24
-
-
0028937232
-
Conformational studies on plasminogen activator inhibitor (PAI-I) in active, latent, substrate, and cleaved forms
-
Sancho E, Declerck PJ, Price NC, Kelly SM and Booth NA (1995) Conformational studies on plasminogen activator inhibitor (PAI-I) in active, latent, substrate, and cleaved forms. Biochemistry 34: 1064-1069
-
(1995)
Biochemistry
, vol.34
, pp. 1064-1069
-
-
Sancho, E.1
Declerck, P.J.2
Price, N.C.3
Kelly, S.M.4
Booth, N.A.5
-
25
-
-
0028081298
-
Inactive urokinase and increased levels of inhibitor type I in colorectal cancer liver metastasis
-
Sier CFM, Vloedgraven HJM, Ganesh S, Griffion G, Quax PHA, Verheijen JH, Dooijewaard G, Welvaart K, van de Velde CJH, Lamers CBHW and Verspaget H (1994) Inactive urokinase and increased levels of inhibitor type I in colorectal cancer liver metastasis. Gastroenterology 10: 1449-1456
-
(1994)
Gastroenterology
, vol.10
, pp. 1449-1456
-
-
Sier, C.F.M.1
Vloedgraven, H.J.M.2
Ganesh, S.3
Griffion, G.4
Quax, P.H.A.5
Verheijen, J.H.6
Dooijewaard, G.7
Welvaart, K.8
Van De Velde, C.J.H.9
Lamers, C.B.H.W.A.10
Verspaget, H.11
-
26
-
-
0028821827
-
Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model
-
Soff GA, Sanderowitz J, Gately S, Verrusio E, Weiss I, Brem S and Kwaan HC (1995) Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model. J Clin Invest 96: 2593-2600
-
(1995)
J Clin Invest
, vol.96
, pp. 2593-2600
-
-
Soff, G.A.1
Sanderowitz, J.2
Gately, S.3
Verrusio, E.4
Weiss, I.5
Brem, S.6
Kwaan, H.C.7
-
27
-
-
0029745109
-
The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin
-
Stefansson S and Lawrence DA (1996) The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin. Nature 383: 441-443
-
(1996)
Nature
, vol.383
, pp. 441-443
-
-
Stefansson, S.1
Lawrence, D.A.2
-
28
-
-
0033559607
-
The plasminogen-plasminogen activator (PA) system in neuroblastoma: Role of PA inhibitor-1 in metastasis
-
Sugiura Y, Ma L, Sun B, Shimada H. Laug WE, Seeger RC and DeClerck Y (1999) The plasminogen-plasminogen activator (PA) system in neuroblastoma: role of PA inhibitor-1 in metastasis. Cancer Res 59: 1327-1336
-
(1999)
Cancer Res
, vol.59
, pp. 1327-1336
-
-
Sugiura, Y.1
Ma, L.2
Sun, B.3
Shimada, H.4
Laug, W.E.5
Seeger, R.C.6
DeClerck, Y.7
-
29
-
-
0033580955
-
Accelerated conversion of human plasminogen activator inhibitor-1 to its latent form by antibody binding
-
Verhamme I, Kvassman J, Day D, Debrock S, Vleufels N, Declerck PJ and Shore JD (1999) Accelerated conversion of human plasminogen activator inhibitor-1 to its latent form by antibody binding. J Biol Chem 274: 17511-17517
-
(1999)
J Biol Chem
, vol.274
, pp. 17511-17517
-
-
Verhamme, I.1
Kvassman, J.2
Day, D.3
Debrock, S.4
Vleufels, N.5
Declerck, P.J.6
Shore, J.D.7
-
30
-
-
0031791204
-
Evaluation of the mechanism of inactivation of plasminogen activator-1 by monoclonal antibodies using a stable variant
-
Vleugels N, Gils A, Mannaerts S, Knockaert I and Declerck PJ (1998) Evaluation of the mechanism of inactivation of plasminogen activator-1 by monoclonal antibodies using a stable variant. Fibrinolysis Protelysis 12: 277-282
-
(1998)
Fibrinolysis Proteolysis
, vol.12
, pp. 277-282
-
-
Vleugels, N.1
Gils, A.2
Mannaerts, S.3
Knockaert, I.4
Declerck, P.J.5
-
31
-
-
0030757506
-
Plasmin and plasminogen activator inhibitor type I promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin
-
Waltz DA, Natkin LR, Fujita RM, Wei Y and Chapman HA (1997) Plasmin and plasminogen activator inhibitor type I promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin. J Clin Invest 100: 58-67
-
(1997)
J Clin Invest
, vol.100
, pp. 58-67
-
-
Waltz, D.A.1
Natkin, L.R.2
Fujita, R.M.3
Wei, Y.4
Chapman, H.A.5
-
32
-
-
0028569183
-
Identification of the urokinase receptor as an adhesion receptor for vitronectin
-
Wei Y, Waltz DA, Rao N, Drummond RJ, Rosenberg S and Chapman HA (1994) Identification of the urokinase receptor as an adhesion receptor for vitronectin. J Biol Chem 269: 32380-32388
-
(1994)
J Biol Chem
, vol.269
, pp. 32380-32388
-
-
Wei, Y.1
Waltz, D.A.2
Rao, N.3
Drummond, R.J.4
Rosenberg, S.5
Chapman, H.A.6
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