메뉴 건너뛰기




Volumn 59, Issue 20, 1999, Pages 5307-5314

Urokinase receptor interacts with α(v)β5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; INTEGRIN; PROTEIN KINASE C; UROKINASE; UROKINASE RECEPTOR; VITRONECTIN RECEPTOR;

EID: 0032698213     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (157)

References (58)
  • 1
    • 0030769477 scopus 로고    scopus 로고
    • General mechanism of metastasis
    • Phila.
    • Woodhouse, E. C., Chuaqui, R. F., and Liotta, L. A. General mechanism of metastasis. Cancer (Phila.), 80: 1529-1537, 1997.
    • (1997) Cancer , vol.80 , pp. 1529-1537
    • Woodhouse, E.C.1    Chuaqui, R.F.2    Liotta, L.A.3
  • 2
    • 0027994264 scopus 로고
    • The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion
    • Dano, K., Behrendt, N., Brunner, N., Ellis, V., Ploug, M., and Pyke, C. The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion. Fibrinolysis, 8: 189-203, 1994.
    • (1994) Fibrinolysis , vol.8 , pp. 189-203
    • Dano, K.1    Behrendt, N.2    Brunner, N.3    Ellis, V.4    Ploug, M.5    Pyke, C.6
  • 4
    • 0029682495 scopus 로고    scopus 로고
    • Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: Cellular blue nevi invade but not progress to malignant melanoma in uPA-deficient animals
    • Shapiro, R. L., Duquette, J. G., Roses, D. F., Nunes, I., Harris, M. N., Kamino, H., Wilson, E. L., and Rifkin, D. B. Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but not progress to malignant melanoma in uPA-deficient animals. Cancer Res., 56: 3597-3604, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3597-3604
    • Shapiro, R.L.1    Duquette, J.G.2    Roses, D.F.3    Nunes, I.4    Harris, M.N.5    Kamino, H.6    Wilson, E.L.7    Rifkin, D.B.8
  • 5
    • 2042503759 scopus 로고
    • Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line
    • Kirchheimer, J. C., Woita, J., Christ, J., and Binder, R. R. Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line. Proc. Natl. Acad. Sci. USA, 86: 5424-5428, 1989.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5424-5428
    • Kirchheimer, J.C.1    Woita, J.2    Christ, J.3    Binder, R.R.4
  • 6
    • 0028331139 scopus 로고
    • The urokinase receptor is required for human monocyte chemotaxis in vitro
    • Gyetko, M. R., Todd, R. F., III, Wilkinson, C. C., and Sitrin, R. G. The urokinase receptor is required for human monocyte chemotaxis in vitro. J. Clin. Invest., 93: 1380-1387, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1380-1387
    • Gyetko, M.R.1    Todd R.F. III2    Wilkinson, C.C.3    Sitrin, R.G.4
  • 7
    • 0027174189 scopus 로고
    • Cytokines induce urokinase-dependent adhesion of human myeloid cells: A regulatory role for plasminogen activator inhibitors
    • Waltz, D. A., Sailor, L. Z., and Chapman, H. A. Cytokines induce urokinase-dependent adhesion of human myeloid cells: a regulatory role for plasminogen activator inhibitors. J. Clin. Invest., 91: 1541-1552, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1541-1552
    • Waltz, D.A.1    Sailor, L.Z.2    Chapman, H.A.3
  • 8
    • 0001149917 scopus 로고
    • Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes
    • Stoppelli, M. P., Corti, A., Soffientini, A., Cassani, G., Blasi, F., and Assoian, R. K. Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes. Proc. Natl. Acad. Sci. USA, 832: 4939-4943, 1985.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.832 , pp. 4939-4943
    • Stoppelli, M.P.1    Corti, A.2    Soffientini, A.3    Cassani, G.4    Blasi, F.5    Assoian, R.K.6
  • 9
    • 0028569183 scopus 로고
    • Identification of the urokinase receptor as an adhesion receptor for vitronectin
    • Wei, Y., Waltz, D. A., Rao, N., Drummend, R. J., Rosenberg, S., and Chapman, H. A Identification of the urokinase receptor as an adhesion receptor for vitronectin. J. Biol. Chem., 269: 32380-32388, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32380-32388
    • Wei, Y.1    Waltz, D.A.2    Rao, N.3    Drummend, R.J.4    Rosenberg, S.5    Chapman, H.A.6
  • 10
    • 0028305433 scopus 로고
    • Induction of cell migration by pro-urokinase binding to its receptor: Possible mechanism for signal transduction in human epithelial cells
    • Busso, N., Masur, S. K., Lazega, D., Waxman, S., and Ossowski, L. Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells. J. Cell. Biol., 126: 259-270, 1994.
    • (1994) J. Cell. Biol. , vol.126 , pp. 259-270
    • Busso, N.1    Masur, S.K.2    Lazega, D.3    Waxman, S.4    Ossowski, L.5
  • 11
    • 0031684740 scopus 로고    scopus 로고
    • Urokinase-dependent angiogenesis in vitro and diacylglycerol production are blocked by antisense oligonucleotides against the urokinase receptor
    • Fibbi, G., Caldini, R., Chevanne, M., Pucci, M., Schiavone, N., Morbidelli, L., Parenti, A., Granger, H. J., Del Rosso, M., Ziche, M. Urokinase-dependent angiogenesis in vitro and diacylglycerol production are blocked by antisense oligonucleotides against the urokinase receptor. Lab. Invest., 78: 1109-1119, 1998.
    • (1998) Lab. Invest. , vol.78 , pp. 1109-1119
    • Fibbi, G.1    Caldini, R.2    Chevanne, M.3    Pucci, M.4    Schiavone, N.5    Morbidelli, L.6    Parenti, A.7    Granger, H.J.8    Del Rosso, M.9    Ziche, M.10
  • 12
    • 0029923744 scopus 로고    scopus 로고
    • Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect
    • Resnati, M., Guttinger, M., Valcamonica, S., Sidenius, N., Blasi, F., and Fazioli, F. Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect. EMBO J., 15, 1572-1582, 1996.
    • (1996) EMBO J. , vol.15 , pp. 1572-1582
    • Resnati, M.1    Guttinger, M.2    Valcamonica, S.3    Sidenius, N.4    Blasi, F.5    Fazioli, F.6
  • 14
    • 0028944244 scopus 로고
    • The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae
    • Stahl, H., and Mueller, B. A. The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae. J. Cell Biol., 129: 335-344, 1995.
    • (1995) J. Cell Biol. , vol.129 , pp. 335-344
    • Stahl, H.1    Mueller, B.A.2
  • 19
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes, R. O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell, 69: 11-25, 1992.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 20
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark, E. A., and Brugge, J. S. Integrins and signal transduction pathways: the road taken. Science (Washington DC), 268: 233-239, 1995.
    • (1995) Science Washington DC , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 22
    • 0030661566 scopus 로고    scopus 로고
    • Integrins, oncogenes and anchorage-independence
    • Schwartz, M. A. Integrins, oncogenes and anchorage-independence. J. Cell Biol., 139: 575-578, 1997.
    • (1997) J. Cell Biol. , vol.139 , pp. 575-578
    • Schwartz, M.A.1
  • 23
    • 0026644051 scopus 로고
    • Integrins and their accessory adhesion molecules in mammary carcinomas: Loss of polarization in poorly differentiated tumors
    • Pignatelli, M., Cardillo, M. R., Hanby, A., and Stamp, G. W. H. Integrins and their accessory adhesion molecules in mammary carcinomas: loss of polarization in poorly differentiated tumors. Hum. Pathol., 23: 1159-1166, 1992.
    • (1992) Hum. Pathol. , vol.23 , pp. 1159-1166
    • Pignatelli, M.1    Cardillo, M.R.2    Hanby, A.3    Stamp, G.W.H.4
  • 24
    • 0032540943 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells
    • Tang, H., Kerins, D. M., Hao, Q., Inagami, T., and Vaughan, D. E. The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells. J. Biol. Chem., 273: 18268-18272, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18268-18272
    • Tang, H.1    Kerins, D.M.2    Hao, Q.3    Inagami, T.4    Vaughan, D.E.5
  • 25
    • 0030916129 scopus 로고    scopus 로고
    • 3 integrins of fibrosarcoma cells: Dependence on extracellular matrix components
    • 3 integrins of fibrosarcoma cells: dependence on extracellular matrix components. Cancer Res., 57: 1682-1689, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1682-1689
    • Xue, W.1    Mizukami, I.2    Todd R.F. III3    Petty, H.R.4
  • 26
    • 0030842795 scopus 로고    scopus 로고
    • Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration
    • Chapman, H. A. Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration. Curr. Opin. Cell Biol., 9: 714-724, 1997.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 714-724
    • Chapman, H.A.1
  • 27
    • 0030759096 scopus 로고    scopus 로고
    • UPA, uPAR, PAI-1: Key intersection of proteolytic, adhesive and chemotactic highways?
    • Blasi, F. uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways? Trends Immunol. Today, 18: 415-417, 1997.
    • (1997) Trends Immunol. Today , vol.18 , pp. 415-417
    • Blasi, F.1
  • 28
    • 0029816265 scopus 로고    scopus 로고
    • Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
    • Deng, G., Curriden, S. A., Wang, S., Rosenberg, S., and Loskutoff, D. J. Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J. Cell Biol., 134:1563-1571, 1996.
    • (1996) J. Cell Biol. , vol.134 , pp. 1563-1571
    • Deng, G.1    Curriden, S.A.2    Wang, S.3    Rosenberg, S.4    Loskutoff, D.J.5
  • 34
    • 0029759727 scopus 로고    scopus 로고
    • 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation
    • 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. J. Cell Biol., 134: 1323-1332, 1996.
    • (1996) J. Cell Biol. , vol.134 , pp. 1323-1332
    • Lewis, J.M.1    Cheresh, D.A.2    Schwartz, M.A.3
  • 35
    • 0028090482 scopus 로고
    • Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies
    • Carriero, M. V., Franco, P., Del Vecchio, S., Massa, O., Botti, G., D'Aiuto, G., Stoppelli, M. P., and Salvatore, M. Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies. Cancer Res., 54: 5445-5454, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 5445-5454
    • Carriero, M.V.1    Franco, P.2    Del Vecchio, S.3    Massa, O.4    Botti, G.5    D'Aiuto, G.6    Stoppelli, M.P.7    Salvatore, M.8
  • 38
    • 0025895086 scopus 로고
    • 5 contribute to cell attachment to vitroneclin but differentially distribute on the cell surface
    • 5 contribute to cell attachment to vitroneclin but differentially distribute on the cell surface. J. Cell Biol., 113: 919-929, 1991.
    • (1991) J. Cell Biol. , vol.113 , pp. 919-929
    • Wayner, E.A.1    Orlando, R.A.2    Cheresh, D.A.3
  • 39
    • 0024376477 scopus 로고
    • A novel integrin β subunit is associated with the vitronectin receptor α subunit (αv) in a human osteosarcoma cell line and is a substrate for protein kinase C
    • Freed, E., Gailit, J., Van Der Geer, P., Ruoslahti, E., and Hunter, T. A novel integrin β subunit is associated with the vitronectin receptor α subunit (αv) in a human osteosarcoma cell line and is a substrate for protein kinase C. EMBO J., 8: 2955-2965, 1989.
    • (1989) EMBO J. , vol.8 , pp. 2955-2965
    • Freed, E.1    Gailit, J.2    Van Der Geer, P.3    Ruoslahti, E.4    Hunter, T.5
  • 42
    • 0025052018 scopus 로고
    • Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis
    • Roldan, A., Cubellis, M. V., Masucci, M. T., Beherendt, N., Lund, L. R., Dano, K., Appella, E., and Blasi, F. Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J., 9: 467-474, 1990.
    • (1990) EMBO J. , vol.9 , pp. 467-474
    • Roldan, A.1    Cubellis, M.V.2    Masucci, M.T.3    Beherendt, N.4    Lund, L.R.5    Dano, K.6    Appella, E.7    Blasi, F.8
  • 44
    • 0027772194 scopus 로고
    • Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization
    • Zutter, M. M., Krigman, H. R., and Santoro, S. A. Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization. Am. J. Pathol., 142: 1439-1448, 1993.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1439-1448
    • Zutter, M.M.1    Krigman, H.R.2    Santoro, S.A.3
  • 48
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver, V. M., Petersen, O. W., Wang, F., Larabell, C. A., Briand, P., Damasky, C., and Bissell, M. J. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol., 137: 231-245, 1997.
    • (1997) J. Cell Biol. , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damasky, C.6    Bissell, M.J.7
  • 50
    • 0029130811 scopus 로고
    • In vitro regulation of human breast cancer cell adhesion and invasion via integrin receptors to the extracellular matrix
    • Gui, G. P. H., Puddefoot, J. R., Vinson, G. P., Wells, C. A., and Carpenter, R. In vitro regulation of human breast cancer cell adhesion and invasion via integrin receptors to the extracellular matrix. Br. J. Surg., 82: 1192-1196, 1995.
    • (1995) Br. J. Surg. , vol.82 , pp. 1192-1196
    • Gui, G.P.H.1    Puddefoot, J.R.2    Vinson, G.P.3    Wells, C.A.4    Carpenter, R.5
  • 51
    • 0030068772 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator reversibly dissociates from complement receptor type 3 (aMb2. CD11b/CD18) during neutrophil polarization
    • Kindzelskii, A. L., Laska, Z. O., Todd, R. F., III, and Petty, H. R. Urokinase-type plasminogen activator reversibly dissociates from complement receptor type 3 (aMb2. CD11b/CD18) during neutrophil polarization. J. Immunol., 157: 297-309, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 297-309
    • Kindzelskii, A.L.1    Laska, Z.O.2    Todd R.F. III3    Petty, H.R.4
  • 52
    • 0010712792 scopus 로고    scopus 로고
    • Disruption of angiogenesis by PEX, a non catalytic metalloproteinase fragment with integrin binding activity
    • Brooks, P. C., Silletti, S., Von Schalscha, T. L., Friedlander, M., and Cheresh, D. A. Disruption of angiogenesis by PEX, a non catalytic metalloproteinase fragment with integrin binding activity. Cell, 92: 391-400, 1998.
    • (1998) Cell , vol.92 , pp. 391-400
    • Brooks, P.C.1    Silletti, S.2    Von Schalscha, T.L.3    Friedlander, M.4    Cheresh, D.A.5
  • 54
    • 0027172158 scopus 로고
    • Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: Comparison with urokinase levels
    • Del Vecchio, S., Stoppelli, M. P., Carriero, M. V., Fonti, R., Massa, O., Li, P. Y., Botti, G., Cerra, M., D'Aiuto, G., Esposito, G., and Salvatore, M. Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: comparison with urokinase levels. Cancer Res., 53: 3198-3206, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3198-3206
    • Del Vecchio, S.1    Stoppelli, M.P.2    Carriero, M.V.3    Fonti, R.4    Massa, O.5    Li, P.Y.6    Botti, G.7    Cerra, M.8    D'Aiuto, G.9    Esposito, G.10    Salvatore, M.11
  • 55
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • Andreasen, P. A., Kjoller, L., Christensen, L., and Duffy, M. J. The urokinase-type plasminogen activator system in cancer metastasis: a review. Int. J. Cancer, 72: 1-22, 1997.
    • (1997) Int. J. Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjoller, L.2    Christensen, L.3    Duffy, M.J.4
  • 56
    • 0028049194 scopus 로고
    • Urokinase-type plasminogen activator and its receptor: New targets for anti-metastatic therapy?
    • Fazioli, F., and Blasi, F. Urokinase-type plasminogen activator and its receptor: new targets for anti-metastatic therapy? Trends Pharmacol. Sci., 15: 25-29, 1994.
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 25-29
    • Fazioli, F.1    Blasi, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.