Effects of sucrose and cornstarch on 2-amino-3-methylimidazo[4,5-f] quinoline (IQ)-induced colon and liver carcinogenesis in F344 rats

Cancer Letters

Volumn 209, Issue 1, 2004, Pages 17-24

  Lindecrona, Rikke Hvid ^a   Dragsted, Lars Ove ^a   Poulsen, Morten ^a   Vogel, Ulla ^c   Autrup, Herman ^b   Mølck, Anne Marie ^a  

^a DANISH VETERINARY AND FOOD ADMINISTRATION   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

Author keywords

Aberrant crypt foci; Colon cancer; Liver cancer; Starch; Sucrose

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; MESSENGER RNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; STARCH; SUCROSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; COLON CARCINOGENESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CRYPT CELL; DIETARY INTAKE; DNA ADDUCT; DNA REPAIR; ENZYME LOCALIZATION; GENE EXPRESSION; LIVER; LIVER CARCINOGENESIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STATISTICAL ANALYSIS;

ANIMALS; BODY WEIGHT; CARBOHYDRATES; CARCINOGENS; CELL DIVISION; COLON; DNA ADDUCTS; DNA REPAIR; GLUTATHIONE TRANSFERASE; LIVER; LIVER NEOPLASMS; MALE; ORGAN SIZE; PLACENTA; QUINOLINES; RATS; RATS, INBRED F344; STARCH; SUCROSE;

ANIMALIA;

EID: 2442457010     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2003.12.008     Document Type: Article

References (28)

1. Terry P., Giovannucci E., Michels K.B., Bergkvist L., Hansen H., Holmberg L., Wolk A. Fruit, vegetables, dietary fiber and risk of colorectal cancer. J. Natl Cancer Inst. 93:2001;525-533
2. Potter J.D., Slattery M.L., Bostick R.M., Gapstur S.M. Colon cancer: a review of the epidemiology. Epidemiol. Rev. 15:1993;499-545
3. Burley V.J. Sugar consumption and cancers of the digestive tract. Eur. J. Cancer Prev. 6:1997;422-434
4. Hill M.J., Caygill C.P.J. Sugar intake and the risk of colorectal cancer. Eur. J. Cancer Prev. 8:1999;465-468
5. Slattery M.L., Benson J., Berry T.D., Duncan D., Edwards S.L., Caan B.J., Potter J.D. Dietary sugar and colon cancer. Cancer Epidemiol. Biomarkers Prev. 6:1997;677-685
6. Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J. Nutr. 131:2001;3109S-3120S
7. Luceri C., Caderni G., Lancioni L., Aiolli S., Dolara P., Mastrandrea V., et al. Effects of repeated boluses of sucrose on proliferation and on AOM-induced aberrant crypt foci in rat colon. Nutr. Cancer. 25:1996;187-196
8. Kristiansen E., Meyer O., Thorup I. Refined carbohydrate enhancement of aberrant crypt foci (ACF) in rat colon induced by the food-borne carcinogen 2-amino-3-methyl-imidazo[4, 5-f]quinoline (IQ). Cancer Lett. 105:1996;147-151
9. Mølck A.-M., Meyer O., Kristiansen E., Thorup I. IQ (2-amino-3-methyl-imidazo[4, 5-f]quinoline)-induced aberrant crypt foci and colorectal tumour development in rats fed two different carbohydrate diets. Eur. J. Cancer Prev. 10:2001;501-506
10. Poulsen M., Mølck A.-M., Thorup I., Breinholt V., Meyer O. The influence of simple sugars and starch given during pre- or post-initiation on aberrant crypt foci in rat colon. Cancer Lett. 167:2001;135-143
11. Caderni G., Luceri C., Spagnesi M.T., Giannini A., Biggeri A., Dolara P. Dietary carbohydrates modify azoxymethane-induced intestinal carcinogenesis in rats. J. Nutr. 124:1994;517-523
12. Kristiansen E., Meyer O., Thorup I. Influence of different diets on development of DMH-induced aberrant crypt foci and colon tumor incidence in Wistar rats. Nutr. Cancer. 23:1995;151-159
13. Bird R.P., McLellan E.A., Bruce W.R. Aberrant crypts, putative precancerous lesions, in the study of the role of diet in the aetiology of colon cancer. Cancer Surv. 8:1989;189-200
14. Thorup I. Histomorphological and immunohistochemical characterization of colonic aberrant crypt foci in rats: relationship to growth factor expression. Carcinogenesis. 18:1997;465-472
15. Dragsted L.O., Daneshvar B., Vogel U., Autrup H.N., Wallin H., Risom L., et al. A sucrose-rich diet induces mutations in the rat colon. Cancer Res. 62:2002;4339-4345
16. Sakata T. Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for the trophic effects of fermentable fibre, gut microbes and luminal trophic factors. Br. J. Nutr. 58:1987;95-103
17. Zhang J., Lupton J.R. Dietary fibers stimulate colonic cell proliferation by different mechanisms at different sites. Nutr. Cancer. 22:1994;267-276
18. Johnson I.T. Butyrate and markers of neoplastic change in the colon. Eur. J. Cancer Prev. 4:1995;365-371
19. Breinholt V.M., Svendsen G.W., Daneshvar B., Vinggaard A.M., Poulsen M., Mølck A.-M., Dragsted L.O. Effects of dietary antioxidants and 2-amino-3-methyl-imidazo[4, 5-f]quinoline (IQ) on preneoplastic lesions and on oxidative damage, hormonal status, and detoxification capacity in the rat. Food Chem. Toxicol. 41:2003;1315-1323
20. Mohr U. International Agency for Research on Cancer (IARC) Scientific publication no. 122. International classification of rodent tumours. Part I: The rat. 1997;56-64 International Agency for Research on Cancer, France
21. Møller P., Hansen M., Autrup H., Bomholt J., Vogel U., Mølck A.-M., et al. Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of Big Blue™ rats. Mutat. Res. 527:2003;91-97
22. Peters L.P., Teel R.W. Effect of high sucrose diet on cytochrome P450 1A and heterocyclic amine mutagenesis. Anticancer Res. 23:2003;399-403
23. Caderni G., Femia A.P., Giannini A., Favuzza A., Luceri C., Salvadori M., Dolara P. Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res. 63:2003;2388-2392
24. Thorup I., Meyer O., Kristiansen E. Effect of potato starch, cornstarch and sucrose on aberrant crypt foci in rats exposed to azoxymethane. Anticancer Res. 15:1995;2101-2106
25. Caderni G., Bianchini F., Mancina A., Spagnesi M.T., Dolara P. Effect of dietary carbohydrates on the growth of dysplastic crypt foci in the colon of rats treated with 1, 2-dimethylhydrazine. Cancer Res. 51:1991;3721-3725
26. Corpet D.E., Stamp D., Medline A., Minkin S., Archer M.C., Bruce W.R. Promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat. Cancer Res. 50:1990;6955-6958
27. Wolowski I., Rechkemmer G., Pool-Zobel B.L. Protective role of probiotics and prebiotics in colon cancer. Am. J. Clin. Nutr. 73:2001;451S-455S
28. Foster-Powell K., Holt S., Brand-Miller C. International table of glycemic index and glycemic load values. Am. J. Clin. Nutr. 76:(2002):2002;5-56