Refined carbohydrate enhancement of aberrant crypt foci (ACF) in rat colon induced by the food-borne carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)

Cancer Letters

Volumn 105, Issue 2, 1996, Pages 147-151

  Kristiansen, Eva ^a   Meyer, Otto ^a   Thorup, Inger ^a  

^a National Food Agency of Denmark   (Denmark)

Author keywords

2 Amino 3 methyl imidazo 4,5 f quinoline (IQ); Aberrant crypt foci; Colon; Rats; Refined carbohydrates

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; CARBOHYDRATE; CARCINOGEN; DEXTRIN; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; COLON CARCINOGENESIS; CONTROLLED STUDY; INTESTINE CRYPT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030564981     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04281-4     Document Type: Article

References (30)

1. [1] Bird, R.P. (1995) Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett., 93, 55-71.
2. [2] Bird, R.P., McLellan, E.A. and Bruce, W.R. (1989) Aberrant crypts, putative precancerous lesions, in the study of the role of diet in the aetiology of colon cancer. Cancer Surv., 8, 189-200.
3. [3] Pretlow, T.P., Barrow, B.J., Ashton, W.S., O'Riordan, M.A., Pretlow, T.G., Jurcisek, J.A. and Stellate, T.A. (1991) Aberrant crypts: putative preneoplastic foci in human colonic mucosa. Cancer Res., 51, 1564-1567.
4. [4] Roncucci, L., Stamp, D., Medline, A., Cullen, J.B. and Bruce, W.R, (1991) Identification and quantification of aberrant crypt foci and microadenomas in the human colon. Hum. Pathol., 22, 287-294.
5. [5] Roncucci, L., Medline, A. and Bruce, W.R. (1991) Classification of aberrant crypt foci and microadenomas in human colon. Cancer Epidemiol. Biomarkers Prev., 1, 57-60.
6. [6] Felton, J.S. and Knize, M.G. (1991) Occurrence, identification and bacterial mutagenicity of heterocyclic amines in cooked food. Mutat. Res., 259, 205-217.
7. [7] Kristiansen, E., Meyer, O. and Thorup, I. (1996) The ability of two cooked food mutagens to induce aberrant crypt foci in mice. Eur. J. Cancer Prev., in press.
8. [8] Kristiansen, E., Thorup, I. and Meyer, O. (1995) Influence of different diets on development of DMH-nduced aberrant crypt foci and colon tumor incidence in Wistar rats. Nutr. Cancer, 23, 151-159.
9. [9] Caderni, G., Bianchini, F., Mancina, A., Spagnesi, M.T. and Dolara, P. (1991) Effect of dietary carbohydrates on the growth of dysplastic crypt foci in the colon of rats treated with 1,2-dimethylhydrazine. Cancer Res., 51, 3721-3725.
10. [10] Stamp, D., Zhang, X.-M., Medline, A., Bruce, W.R. and Archer, M.C. (1993) Sucrose enhancement of the early steps of colon carcinogenesis in mice. Carcinogenesis, 14, 777-779.
11. [11] Meyer, O., Blom, L. and Søndergaard, D. (1982) The influence of minerals and protein on the nephrocalcinosis potential for rats of semisynthetic diets. Lab. Anim., 16, 271-273.
12. [12] Takayama, S., Nakatsuru, Y., Masuda, M., Ohgaki, H., Sato, S. and Sugimura, T. (1984) Demonstration of carcinogenicity in F-344 rats of 2-amino-3-methyl-imidazo[4,5-f]quinoline from broiled sardine, fried beef and beef extract. Gann, 75, 467-470.
13. [13] Tudek, B., Bird, R.P. and Bruce, W.R. (1989) Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods. Cancer Res., 49, 1236-1240.
14. [14] Tachino, N., Hayashi, R., Liew, C., Bailey, G. and Dashwood, R.H. (1995) Evidence for ras gene mutation in 2-amino-3-methylimidazo[4,5-f]quinoline-induced colonic aberrant crypts in the rat. Mol. Carcinogenesis, 12, 187-192.
15. [15] Liew, C., Schut, H.A.J., Chin, S.F., Pariza, M.W. and Dashwood, R.H. (1995) Protection of conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms. Carcinogenesis, 16, 3037-3043.
16. [16] Thorup, I., Meyer, O. and Kristiansen, E. (1995) Effect of potato starch, cornstarch and sucrose on aberrant crypt foci in rats exposed to azoxymethane. Anticancer Res., 15, 2101-2106.
17. [17] La Vecchia, C., Franceschi, S., Dolara, P., Bidoli, E. and Barbone, F. (1993) Refined-sugar intake and the risk of colorectal cancer in humans. Int. J. Cancer, 55, 386-389.
18. [18] Bristol, J.B., Emmett, P.M., Heaton, K.W. and Williamson, R.C.N. (1985) Sugar, fat, and the risk of colorectal cancer. Br. Med. J., 291, 1467-1470.
19. [19] Macquart-Moulin, G., Riboli, E., Cornée, J., Kaaks, R. and Berthezène, P. (1987) Colorectal polyps and diet: a case-control study in Marseilles. Int. J. Cancer, 40, 179-188.
20. [20] Tuyns, A.J., Haelterman, M. and Kaaks, R. (1987) Colorectal cancer and the intake of nutrients: oligosaccharides are a risk factor, fats are not. A case-control study in Belgium. Nutr. Cancer, 10, 181-196.
21. [21] Tuyns, A.J., Kaaks, R. and Haelterman, M. (1988) Colorectal cancer and the consumption of foods: a case-control study in Belgium. Nutr. Cancer, 11, 189-204.
22. [22] Guo, D., Schut, H.A.J., Davis, C.D., Snyderwine, E.G., Bailey, G.S, and Dashwood, R.H. (1995) Protection by chlorophyllin and indole-3-carbinol against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced DNA adducts and colonic aberrant crypts in the F344 rat. Carcinogenesis, 16, 2931-2937.
23. [23] Guo, D., Horio, D.T., Grove, J.S. and Dashwood, R.H. (1995) Inhibition by chlorophyllin of 2-amino-3-methyl-imidazo[4,5-f]quinoline-induced tumorigenesis in the male F344 rat. Cancer Lett., 95, 161-165.
24. [24] Pereira, M.A., Barnes, L.H., Rassman, V.L., Kelloff, G.V. and Steele, V.E. (1994) Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents. Carcinogenesis 15, 1049-1054.
25. [25] Nelson, R.L. (1992) Chlorophyllin, an antimutagen, acts as a tumor promoter in the rat-dimethylhydrazine colon carcinogenesis model. Anticancer Res., 12, 737-740.
26. [26] Pence, B.C., Buddingh, F. and Yang, S.P. (1986) Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol. J. Natl. Cancer Inst., 77, 269-276.
27. [27] Davis, C.D., Schut, H.A., Adamson, R.H., Thorgeirsson, U.P., Thorgeirsson, S.S. and Snyderwine, E.G. (1993) Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rats, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo. Carcinogenesis, 14, 61-65.
28. [28] Rumney, C.J., Rowland, I.R. and O'Neill, I.K. (1993) Conversion of IQ to 7-OHIQ by gut microflora. Nutr. Cancer, 19, 67-76.
29. [29] Weisburger, J.H., Rivenson, A., Reinhardt, J., Aliaga, C., Braley, J., Dolan, L.M., Williams, G.M., Zang, E., Kingston, D.G.I., Bashir, M., Shu, Y.Z., Wilkins, T.D. and Van Tassell, R.L. (1994) Genotoxicity and carcinogenicity in rats and mice of 2-amino-3,6-dihydro-3-methyl-7H-imidazolo[4,5-f]quinolin-7-one: an intestinal bacterial metabolite of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline. J. Natl. Cancer Inst., 86, 25-30.
30. [30] Kajikawa, A., Umemoto, A., Hamada, K., Tanaka, M., Kinouchi, T., Ohnishi, Y. and Monden, Y. (1995) Mucosa-preferential DNA adduct formation by 2-amino-3-methyl-imidazo[4,5-f]quinoline in the rat colonic wall. Cancer Res., 55, 2769-2773.