IQ (2-amino-3-methylimidazo[4,5-f]quinoline)-induced aberrant crypt foci and colorectal tumour development in rats fed two different carbohydrate diets

European Journal of Cancer Prevention

Volumn 10, Issue 6, 2001, Pages 501-506

  Molck A M ^a   Meyer, O ^a   Kristiansen, E ^a   Thorup, I ^a  

^a DANISH VETERINARY AND FOOD ADMINISTRATION   (Denmark)

Author keywords

Aberrant crypt foci; Colorectal tumour; IQ; Rats; Refined carbohydrates; Sucrose

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; CARBOHYDRATE; CARCINOGEN; SUGAR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CARBOHYDRATE DIET; CHEMICAL CARCINOGENESIS; COLON TUMOR; COLORECTAL TUMOR; CORRELATION FUNCTION; CRYPT CELL; FEEDING; LIVER TUMOR; MALE; NONHUMAN; ONSET AGE; PRIORITY JOURNAL; RAT; SKIN TUMOR; SUGAR INTAKE;

ADMINISTRATION, ORAL; ANIMALS; CARCINOGENS; COLORECTAL NEOPLASMS; DIETARY SUCROSE; DISEASE MODELS, ANIMAL; FOOD, FORMULATED; LIVER NEOPLASMS; MALE; PRECANCEROUS CONDITIONS; QUINOLINES; RANDOM ALLOCATION; RATS; RATS, INBRED F344; SKIN NEOPLASMS;

EID: 0035680038     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008469-200112000-00004     Document Type: Article

References (36)

1. Role of aberrant crypt foci in understanding the pathogenesis of colon cancer
2. Aberrant crypt foci system to study cancer preventive agents in the colon
3. Aberrant crypts, putative precancerous lesions, in the study of the role of diet in the aetiology of colon cancer
4. Review. Sugar consumption and cancers of the digestive tract
5. Effect of dietary carbohydrates on the growth of dysplastic crypt foci in the colon of rats treated with 1,2-dimethyl-hydrazine
6. Dietary carbohydrates modify azoxymethane-induced intestinal carcinogenesis in rats
7. Dietary sucrose and starch affect dysplastic characteristics in carcinogen-induced aberrant crypt foci in rat colon
8. Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: Low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo
9. Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats
10. Occurrence, identification and bacterial mutagenicity of heterocyclic amines in cooked food
11. Butyrate and markers of neoplastic change in the colon
12. Effect of dietary oxidized cholesterol on azoxymethane-induced colonic preneoplasia in mice
13. Influence of different diets on development of DMH-induced aberrant crypt foci and colon tumor incidence in Wistar rats
14. Refined carbohydrate enhancement of aberrant crypt foci (ACF) in rat colon induced by the food-borne carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)
15. Protection of conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: A study of inhibitory mechanisms
16. Effects of repeated boluses of sucrose on proliferation and on AOM-induced aberrant crypt foci in rat colon
17. The influence of minerals and protein on the nephrocalcinosis potential for rats of semisynthetic diet
18. Carcinogenicity in mice and rats of heterocyclic amines in cooked foods
19. Carcinogenicities of heterocyclic amines in cooked food
20. Aberrant crypts: Putative preneoplastic foci in human colonic mucosa
21. Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline, a food mutagen
22. Classification of aberrant crypt foci and microadenomas in human colon
23. Identification and quantification of aberrant crypt foci and microadenomas in the human colon
24. Summation of initiation activities of low doses of the non-hepatocarcinogen 1,2-dimethylhydrazine in the liver after carbon tetrachloride administration
25. Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: A possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors
26. Cooking procedures and food mutagens: A literature review
27. Sucrose enhancement of the early steps of colon carcinogenesis in mice
28. Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process
29. Evidence for ras gene mutation in 2-amino-3-methyl-imidazo[4,5-f]quinoline-induced colonic aberrant crypts in the rat
30. Demonstration of carcinogenicity in F344 rats of 2-amino-3-methyl-imidazo[4,5-f]quinoline from broiled sardine, fried beef and beef extract
31. Effect of potato starch, corn starch and sucrose on aberrant crypt foci in rats exposed to azoxymethane
32. Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods
33. Dietary protein and chronic toxicity of 1,2-demethylhydrazine fed to mice
34. Effects of delays in the cell cycle on the induction of preneoplastic and neoplastic lesions in the rat liver by 1,2-dimethylhydrazine
35. Dietary fibers stimulate colonic cell proliferation by different mechanisms at different sites