Dual inhibitory effects of furonaphthoquinone compound on enzyme activity and lipopolysaccharide-induced expression of cyclooxygenase-2 in macrophages

Biochemical and Biophysical Research Communications

Volumn 336, Issue 1, 2005, Pages 93-99

  Ki, Young Ahn ^a   Byung, Hak Kim ^a   Yong, Rok Lee ^b   Hwang, Dong Hyuck ^a   Eun, Yong Chung ^a   Kyung, Rak Min ^a   Kim, Youngsoo ^a  

^a Chungbuk National University   (South Korea)

^b Yeungnam University   (South Korea)

Author keywords

Cyclooxygenase 2; Furonaphthoquinone compound; Nuclear factor B; Prostaglandin E2

Indexed keywords

2 METHYL 2 (2 METHYLPROPENYL) 2,3 DIHYDRONAPHTHO[2,3 B]FURAN 4,9 DIONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FURONAPHTHOQUINONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; NAPHTHOQUINONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DNA BINDING; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; BASE SEQUENCE; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DNA PRIMERS; DOWN-REGULATION; FURANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NAPHTHOQUINONES; NF-KAPPA B; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 24344483118     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.059     Document Type: Article

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