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Volumn 129, Issue 3, 2005, Pages 952-968

Gastrin suppresses growth of CCK2 receptor expressing colon cancer cells by inducing apoptosis in vitro and in vivo

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 7; CHOLECYSTOKININ B RECEPTOR; GASTRIN 17; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 5; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; OMEPRAZOLE; TRANSCRIPTION FACTOR AP 1;

EID: 24144455998     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2005.06.059     Document Type: Article
Times cited : (34)

References (51)
  • 1
    • 0029794029 scopus 로고    scopus 로고
    • Gastric endocrine cells: Gene expression, processing and targeting of the active products
    • G.J. Dockray, A. Varro, R. Dimaline Gastric endocrine cells gene expression, processing and targeting of the active products Physiol Rev 76 1996 767 798
    • (1996) Physiol Rev , vol.76 , pp. 767-798
    • Dockray, G.J.1    Varro, A.2    Dimaline, R.3
  • 2
    • 0035043906 scopus 로고    scopus 로고
    • Gastrin, CCK, signaling, and cancer
    • E. Rozengurt, J.H. Walsh Gastrin, CCK, signaling, and cancer Annu Rev Physiol 63 2001 49 76
    • (2001) Annu Rev Physiol , vol.63 , pp. 49-76
    • Rozengurt, E.1    Walsh, J.H.2
  • 3
    • 0031902369 scopus 로고    scopus 로고
    • Gastrin, gastrin receptors and colorectal carcinoma
    • G.S. Baldwin, A. Shulkes Gastrin, gastrin receptors and colorectal carcinoma Gut 42 1998 581 584
    • (1998) Gut , vol.42 , pp. 581-584
    • Baldwin, G.S.1    Shulkes, A.2
  • 4
    • 0028892972 scopus 로고
    • Binding of progastrin fragments to the 78 kDa gastrin binding protein
    • G.S. Baldwin Binding of progastrin fragments to the 78 kDa gastrin binding protein FEBS Lett 359 1995 97 100
    • (1995) FEBS Lett , vol.359 , pp. 97-100
    • Baldwin, G.S.1
  • 8
    • 0032980318 scopus 로고    scopus 로고
    • Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells
    • V.M. Stephan, M. Sawada, A. Todisco, C.J. Dickinson Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells Mol Med 5 1999 147 159
    • (1999) Mol Med , vol.5 , pp. 147-159
    • Stephan, V.M.1    Sawada, M.2    Todisco, A.3    Dickinson, C.J.4
  • 9
    • 0033561308 scopus 로고    scopus 로고
    • Over expression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation
    • T.J. Koh, G.J. Dockray, A. Varro, R.J. Cahill, C.A. Dangler, J.G. Fox, T.C. Wang Over expression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation J Clin Invest 103 1999 1119 1126
    • (1999) J Clin Invest , vol.103 , pp. 1119-1126
    • Koh, T.J.1    Dockray, G.J.2    Varro, A.3    Cahill, R.J.4    Dangler, C.A.5    Fox, J.G.6    Wang, T.C.7
  • 10
    • 0030020865 scopus 로고    scopus 로고
    • Gastrimmune raises antibodies that neutralize amidated and glycine-extended gastrin-17 and inhibit growth of colon cancer
    • S.A. Watson, D. Michaeli, S. Grimes, T.M. Morris, G. Robinson, A. Varro, T.A. Justin, J.D. Hardcastle Gastrimmune raises antibodies that neutralize amidated and glycine-extended gastrin-17 and inhibit growth of colon cancer Cancer Res 56 1996 880 885
    • (1996) Cancer Res , vol.56 , pp. 880-885
    • Watson, S.A.1    Michaeli, D.2    Grimes, S.3    Morris, T.M.4    Robinson, G.5    Varro, A.6    Justin, T.A.7    Hardcastle, J.D.8
  • 11
    • 0034789948 scopus 로고    scopus 로고
    • Glycine-extended gastrin promotes the invasiveness of human colon cancer cells
    • S. Kermorgant, T. Lehy Glycine-extended gastrin promotes the invasiveness of human colon cancer cells Biochem Biophys Res Commun 285 2001 136 141
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 136-141
    • Kermorgant, S.1    Lehy, T.2
  • 12
    • 3042736017 scopus 로고    scopus 로고
    • Glycine-extended gastrin induces matrix-metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type 1 collagen gel and Matrigel
    • M. Baba, K. Itoh, M. Tatsuta Glycine-extended gastrin induces matrix-metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type 1 collagen gel and Matrigel Int J Cancer 111 2004 23 31
    • (2004) Int J Cancer , vol.111 , pp. 23-31
    • Baba, M.1    Itoh, K.2    Tatsuta, M.3
  • 13
    • 3042676790 scopus 로고    scopus 로고
    • Gastrins, cholecystokinins and gastrointestinal cancer
    • A. Aly, A. Shulkes, G.S. Baldwin Gastrins, cholecystokinins and gastrointestinal cancer Biochem Biophys Acta 1704 2004 1 10
    • (2004) Biochem Biophys Acta , vol.1704 , pp. 1-10
    • Aly, A.1    Shulkes, A.2    Baldwin, G.S.3
  • 14
    • 0344925874 scopus 로고    scopus 로고
    • 1-80 reduces apoptosis of intestinal epithelial cells and up-regulates cytochrome c oxidase Vb levels and synthesis of ATP
    • 1-80 reduces apoptosis of intestinal epithelial cells and up-regulates cytochrome c oxidase Vb levels and synthesis of ATP Am J Physiol Gastrointest Liver Physiol 285 2003 G1097 G1110
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Wu, H.1    Owlia, A.2    Singh, P.3
  • 15
    • 0035173783 scopus 로고    scopus 로고
    • Plasma levels of progastrin but not amidated gastrin or glycine extended gastrin are elevated in patients with colorectal carcinoma
    • R.K. Siddheshwar, J.C. Gray, S.B. Kelly Plasma levels of progastrin but not amidated gastrin or glycine extended gastrin are elevated in patients with colorectal carcinoma Gut 48 2001 47 52
    • (2001) Gut , vol.48 , pp. 47-52
    • Siddheshwar, R.K.1    Gray, J.C.2    Kelly, S.B.3
  • 19
    • 0034793740 scopus 로고    scopus 로고
    • Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas
    • I. Rooman, J. Lardon, D. Flamez, F. Schuit, L. Bouwens Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas Gastroenterology 121 2001 940 949
    • (2001) Gastroenterology , vol.121 , pp. 940-949
    • Rooman, I.1    Lardon, J.2    Flamez, D.3    Schuit, F.4    Bouwens, L.5
  • 21
    • 0035863511 scopus 로고    scopus 로고
    • Min-/+ mouse model of familial adenomatous polyposis
    • Min-/+ mouse model of familial adenomatous polyposis Cancer Res 61 2001 625 631
    • (2001) Cancer Res , vol.61 , pp. 625-631
    • Watson, S.A.1    Smith, A.M.2
  • 22
    • 1542615086 scopus 로고    scopus 로고
    • An antiapoptotic role for gastrin and the gastrin/CCK-2 receptor in Barrett's esophagus
    • J.C. Harris, P.A. Clarke, A. Awan, J. Jankowski, S.A. Watson An antiapoptotic role for gastrin and the gastrin/CCK-2 receptor in Barrett's esophagus Cancer Res 64 2004 1915 1919
    • (2004) Cancer Res , vol.64 , pp. 1915-1919
    • Harris, J.C.1    Clarke, P.A.2    Awan, A.3    Jankowski, J.4    Watson, S.A.5
  • 23
    • 4444221159 scopus 로고    scopus 로고
    • Intracellular mechanisms mediating the anti-apoptotic action of gastin
    • S. Ramamoorthy, V. Stepan, A. Todisco Intracellular mechanisms mediating the anti-apoptotic action of gastin Biochem Biophys Res Commun 323 2004 44 48
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 44-48
    • Ramamoorthy, S.1    Stepan, V.2    Todisco, A.3
  • 25
    • 0036323006 scopus 로고    scopus 로고
    • Deletion of functional gastrin gene markedly increases colon carcinogenesis in response to azoxymethane in mice
    • S. Cobb, T. Wodd, L. Tessarollo, M. Velasco, R. Given, A. Varro, N. Tarasova, P. Singh Deletion of functional gastrin gene markedly increases colon carcinogenesis in response to azoxymethane in mice Gastroenterology 123 2002 516 530
    • (2002) Gastroenterology , vol.123 , pp. 516-530
    • Cobb, S.1    Wodd, T.2    Tessarollo, L.3    Velasco, M.4    Given, R.5    Varro, A.6    Tarasova, N.7    Singh, P.8
  • 28
    • 0346033449 scopus 로고    scopus 로고
    • Characterization of gastrin-induced cytostatic effect on cell proliferation in experimental malignant gliomas
    • F. Lefranc, N. Sadeghi, T. Metens, J. Brotchi, I. Salmon, R. Kiss Characterization of gastrin-induced cytostatic effect on cell proliferation in experimental malignant gliomas Neurosurgery 52 2003 881 890
    • (2003) Neurosurgery , vol.52 , pp. 881-890
    • Lefranc, F.1    Sadeghi, N.2    Metens, T.3    Brotchi, J.4    Salmon, I.5    Kiss, R.6
  • 29
    • 0035118918 scopus 로고    scopus 로고
    • Gastrin inhibits cholongiocarcinoma growth via increased apoptosis by activation of Ca2+-dependent protein kinase C-α
    • N. Kanno, S. Glaser, U. Chowdhury, J.L. Phinizy, L. Baiocchi, H. Francis, G. LeSage, G. Alpini Gastrin inhibits cholongiocarcinoma growth via increased apoptosis by activation of Ca2+-dependent protein kinase C-α J Hepatol 34 2001 284 291
    • (2001) J Hepatol , vol.34 , pp. 284-291
    • Kanno, N.1    Glaser, S.2    Chowdhury, U.3    Phinizy, J.L.4    Baiocchi, L.5    Francis, H.6    Lesage, G.7    Alpini, G.8
  • 31
    • 3042601107 scopus 로고    scopus 로고
    • Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons
    • T. Takadera, Y. Shiraishi, T. Ohyashiki Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons Neurochem Int 45 2004 713 719
    • (2004) Neurochem Int , vol.45 , pp. 713-719
    • Takadera, T.1    Shiraishi, Y.2    Ohyashiki, T.3
  • 32
    • 3042696851 scopus 로고    scopus 로고
    • Role of progastrins and gastrins and their receptors in GI and pancreatic cancer: Targets for treatment
    • W. Rengifo-Cam, P. Singh Role of progastrins and gastrins and their receptors in GI and pancreatic cancer targets for treatment Curr Pharm Des 10 2004 2345 2358
    • (2004) Curr Pharm des , vol.10 , pp. 2345-2358
    • Rengifo-Cam, W.1    Singh, P.2
  • 34
    • 0038787522 scopus 로고    scopus 로고
    • The putative apoptosis inhibitor IEX-1L is a mutant nonspliced variant of p22(PRG1/IEX-1) and is not expressed in vivo
    • H. Schäfer, A. Arlt, A. Trauzold, A. Hünermann-Jansen, W.E. Schmidt The putative apoptosis inhibitor IEX-1L is a mutant nonspliced variant of p22(PRG1/IEX-1) and is not expressed in vivo Biochem Biophys Res Commun 262 1999 139 145
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 139-145
    • Schäfer, H.1    Arlt, A.2    Trauzold, A.3    Hünermann-Jansen, A.4    Schmidt, W.E.5
  • 36
    • 0030430746 scopus 로고    scopus 로고
    • Pituitary adenylate-cyclase-activating polypeptide stimulates proto-oncogene expression and activates the AP-1 (c-Fos/c-Jun) transcription factor in AR4-2J pancreatic carcinoma cells
    • H. Schäfer, J. Zheng, F. Gundlach, R. Günther, E.G. Siegel, U.R. Fölsch, W.E. Schmidt Pituitary adenylate-cyclase-activating polypeptide stimulates proto-oncogene expression and activates the AP-1 (c-Fos/c-Jun) transcription factor in AR4-2J pancreatic carcinoma cells Eur J Biochem 242 1996 467 476
    • (1996) Eur J Biochem , vol.242 , pp. 467-476
    • Schäfer, H.1    Zheng, J.2    Gundlach, F.3    Günther, R.4    Siegel, E.G.5    Fölsch, U.R.6    Schmidt, W.E.7
  • 37
    • 0032475953 scopus 로고    scopus 로고
    • The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NF-κB
    • H. Schäfer, J. Diebel, A. Arlt, A. Trauzold, W.E. Schmidt The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NF-κB FEBS Lett 436 1998 139 143
    • (1998) FEBS Lett , vol.436 , pp. 139-143
    • Schäfer, H.1    Diebel, J.2    Arlt, A.3    Trauzold, A.4    Schmidt, W.E.5
  • 40
    • 0025980628 scopus 로고
    • Inhibition of cell proliferation by the cholecystokinin antagonist L-364-718
    • C.M. Thumwood, J. Hong, G.S. Baldwin Inhibition of cell proliferation by the cholecystokinin antagonist L-364-718 Exp Cell Res 192 1991 189 192
    • (1991) Exp Cell Res , vol.192 , pp. 189-192
    • Thumwood, C.M.1    Hong, J.2    Baldwin, G.S.3
  • 41
    • 1342267520 scopus 로고    scopus 로고
    • K-ras and B-raf gene mutations are not associated with gastrin- and CCK2 receptor mRNA expression in human colorectal tumour tissues
    • H.-J. Monstein, K. Fransén, J. Dimberg, P. Söderkvist K-ras and B-raf gene mutations are not associated with gastrin- and CCK2 receptor mRNA expression in human colorectal tumour tissues Eur J Clin Invest 34 2004 100 106
    • (2004) Eur J Clin Invest , vol.34 , pp. 100-106
    • Monstein, H.-J.1    Fransén, K.2    Dimberg, J.3    Söderkvist, P.4
  • 42
    • 0036967830 scopus 로고    scopus 로고
    • Effects of amidated gastrin and glycine-extended gastrin on cell proliferation and crypt fission in parenterally and orally fed rats
    • A.J. FitzGerald, M.A. Ghatei, N. Mandir, S.R. Bloom, L. Iversen, R.A. Goodlad Effects of amidated gastrin and glycine-extended gastrin on cell proliferation and crypt fission in parenterally and orally fed rats Digestion 66 2002 58 66
    • (2002) Digestion , vol.66 , pp. 58-66
    • Fitzgerald, A.J.1    Ghatei, M.A.2    Mandir, N.3    Bloom, S.R.4    Iversen, L.5    Goodlad, R.A.6
  • 43
    • 0030699228 scopus 로고    scopus 로고
    • CCK-B receptors produce similar signals but have opposite growth effects on CHO cells and Swiss 3T3 cells
    • K. Detjen, D. Yule, M.-J. Tseng, J.A. Williams, C.D. Logsdon CCK-B receptors produce similar signals but have opposite growth effects on CHO cells and Swiss 3T3 cells Am J Physiol 273 1997 C1449 C1457
    • (1997) Am J Physiol , vol.273
    • Detjen, K.1    Yule, D.2    Tseng, M.-J.3    Williams, J.A.4    Logsdon, C.D.5
  • 44
    • 0031047278 scopus 로고    scopus 로고
    • Transfected CCKA and CCKB receptors mediate growth inhibitory effects on human pancreatic cancer cell lines
    • K. Detjen, M. Fenrich, C.D. Logsdon Transfected CCKA and CCKB receptors mediate growth inhibitory effects on human pancreatic cancer cell lines Gastroenterology 112 1997 952 959
    • (1997) Gastroenterology , vol.112 , pp. 952-959
    • Detjen, K.1    Fenrich, M.2    Logsdon, C.D.3
  • 46
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-edged sword in tumorigenesis
    • R. Eferl, E.F. Wagner AP-1 a double-edged sword in tumorigenesis Nat Rev Cancer 3 2003 859 868
    • (2003) Nat Rev Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 47
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • E. Shaulian, M. Karin AP-1 in cell proliferation and survival Oncogene 20 2001 2390 2400
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 49
    • 2942702021 scopus 로고    scopus 로고
    • Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-κB activation by protein phosphatase 4-mediated NF-κB p65 Thr dephosphorylation
    • P.Y. Yeh, K.H. Yeh, S.E. Chuang, Y.C. Song, A.L. Cheng Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-κB activation by protein phosphatase 4-mediated NF-κB p65 Thr dephosphorylation J Biol Chem 279 2004 26143 26148
    • (2004) J Biol Chem , vol.279 , pp. 26143-26148
    • Yeh, P.Y.1    Yeh, K.H.2    Chuang, S.E.3    Song, Y.C.4    Cheng, A.L.5
  • 50
    • 0038237681 scopus 로고    scopus 로고
    • Gastrin activates nuclear factor-κB (NF-κB) through a protein kinase C dependent pathway involving NF-κB inducing kinase, inhibitor κb (IκB) kinase, and tumour necrosis factor receptor associated factor 6 (TRAF6) in MKN-28 cells transfected with gastrin receptor
    • M. Ogasa, Y. Miyazaki, S. Hiraoka, S. Kitamura, Y. Nagasawa, O. Kishida, T. Miyazaki, T. Kiyohara, Y. Shinomura, Y. Matsuzawa Gastrin activates nuclear factor-κB (NF-κB) through a protein kinase C dependent pathway involving NF-κB inducing kinase, inhibitor κB (IκB) kinase, and tumour necrosis factor receptor associated factor 6 (TRAF6) in MKN-28 cells transfected with gastrin receptor Gut 52 2003 813 819
    • (2003) Gut , vol.52 , pp. 813-819
    • Ogasa, M.1    Miyazaki, Y.2    Hiraoka, S.3    Kitamura, S.4    Nagasawa, Y.5    Kishida, O.6    Miyazaki, T.7    Kiyohara, T.8    Shinomura, Y.9    Matsuzawa, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.