Clinical significance of serum gastrin levels in patients with colorectal cancer

International Journal of Biological Markers

Volumn 19, Issue 1, 2004, Pages 46-51

  Tocchi, Adriano ^a,c   Mazzoni, G ^a   Puma, F ^b   Miccini, M ^a   Daddi, G ^b   Bettelli, E ^a   Cassini, D ^a   Brozzetti, S ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c NONE   (Italy)

Author keywords

Carcinomembryonic antigen; Colorectal cancer; Gastrin

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; GASTRIN;

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL EXAMINATION; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FOLLOW UP; GASTRIN BLOOD LEVEL; GROUPS BY AGE; GROUPS BY SEX; HUMAN; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PROGNOSIS; RADIOIMMUNOASSAY; RADIOLOGICAL PROCEDURES; TUMOR DIFFERENTIATION;

EID: 1942486911     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.5301/JBM.2008.2259     Document Type: Article

References (24)

1. Scotté M, Hoebeke Y, Coquerel A, et al. Gastrinemie préet post-opératoire au cours du cancer colorectal. Résultats préliminaires d'une étude prospective. Gastroenterol Clin Biol 1992; 16: 475-6.
2. Seitz JF, Giovannini M, Delpero JR, et al. Elévation de la gastrinémie chez les patients porteurs d'un cancer colorectal. Gastroenterol Clin Biol 1988; 12: A33.
3. Vanderstraeten EF, De Vos MM, Versieck JM, Elewaut AP. Serum gastrin levels and colorectal neoplasia. Dis Colon Rectum 1995; 38: 172-6.
4. Smith JP, Wood JG, Solomn TE. Elevated gastrin levels in patients with colon cancer or adenomatous polyps. Dig Dis Sci 1989; 34: 171-4.
5. Seitz JF, Giovannini M, Gouvernet J, et al. Elevated serum gastrin levels in patients with colorectal neoplasia. Dis Colon Rectum 1988; 31: 716-7.
6. Winsett OE, Towsend CM, Glass EJ, Thompson JC. Gastrin stimulates growth of colon cancer. Surgery 1986; 99: 302-7.
7. Guo YS, Baijal M, Jin GF, Thompson JC, Towsend CM, Singh P. Growth promoting effects of gastrin on mouse colon cancer cell in vitro: absence of autocrine effects. In Vitro Cell Dev Biol 1990; 26: 871-7.
8. Kusik G, McNeil NO, Johnson LR. Stimulation of growth of a colon cancer cell line by gastrin. Am J Physiol 1986; 251: G597-601.
9. Nemeth J, Taylor B, Pauwels S, Varro A, Dockray GJ. Identification of progastrin derived peptide in colorectal carcinoma extracts. Gut 1993; 34: 90-5.
10. Baldwin GS, Zhang QZ. Measurement of gastrin and transforming growth factor alfa-messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction. Cancer Res 1992; 52: 2261-7.
11. Watson SA, Durrant LG, Wencyk PM, Watson AL, Morris DL. Intracellular gastrin in human gastrointestinal tumor cells. J Natl Cancer Inst 1991; 83: 866-71.
12. Carrol ER, Matkowskyj KA, Chakrabarti TJ, Benya RV. Aberrant expression of gastrin-releasing pepticle and its receptor by well-differentiated colon cancers in humans. Am J Physiol 1999; 259: G655-65.
13. Upp JR, Singh P, Townsend CM, Thompson JC. Clinical significance of gastrin receptors in human colon cancers. Cancer Res 1989; 49: 488-92.
14. Kikendall JW, Glass AR, Sobin LH, Bowen PE. Serum gastrin is not higher in subjects with colonic neoplasia. Am J Gastroenterol 1992; 87: 1394-7.
15. Karlin DA, McBath M, Jones RD, Elwyn KE, Romsdahl MM. Hypergastrinemia and colorectal carcinogenesis in the rat. Cancer Lett 1985; 29: 73-8.
16. McGregor DB, Joes RD, Karlin DA, Romsdahl MM. Trophic effects of gastrin on colorectal neoplasm in the rat. Ann Surg 1982; 195; 219-23.
17. Beuchamp RD, Towsend CM, Singh P, Glass EJ, Thompson JC. Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice. Ann Surg 1985; 202: 303-9.
18. Singh P, Velasco M, Given R, Varro A, Wang TC. Progastrin expression predisposes mice to colon carcinoma and adenomas in response to chemical carcinogen. Gastroenterology 2000; 119: 162-71.
19. Murakami H, Masui H. Hormonal control of human colon carcinoma cell growth in serum-free medium. Proc Natl Acad Sci 1980; 77: 3464-8.
20. Sirinek KR, Levine BA, Moyer M. Pentagastrin stimulates in vitro growth of normal and malignant human colon epithelial cells. Am J Surg 1985; 149: 35-9.
21. Singh P, Rae-Venter B, Towsend CM, Thompson JC. Gastrin receptors in normal and malignant gastrointestinal mucosa: age-associated changes. Am J Physiol 1985; 249: G761-9.
22. Watson SA, Durrant LG, Crosbie JD, Morris DL. The in vitro growth response of primary human colorectal and gastric cancer cells to gastrin. Int J Cancer 1989; 43: 692-6.
23. Baldwin GS, Casey A, Mantamadiotis T, McBride K, Sizeland AM, Thumwood CM. PC cloning and sequence of gastrin mRNA from carcinoma cell lines. Biochem Biophys Res Commun 1990; 170: 691-7.
24. Singh P, Owlia A, Varro A, Dai B, Rajaraman S, Wood T. Gastrin gene expression is required for the proliferation and tumorigenicity of human colon cancer cells. Cancer Res 1996; 56: 4111-5.