Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 284, Issue 2 47-2, 2003, Pages

  Singh, P ^a   Lu, X ^b   Cobb, S ^a   Miller, B T ^a   Tarasova, N ^d   Varro, A ^c   Owlia, A ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b Elim Biopharmaceuticals   (United States)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Confocal microscopy; Gly gastrin; In vitro growth effects; Progastrin preferring receptors

Indexed keywords

CHOLECYSTOKININ RECEPTOR; FLUORESCENT DYE; GASTRIN 17; GROWTH FACTOR; IODINE 125; PROGASTRIN; RECOMBINANT HORMONE; RECOMBINANT HUMAN PROGASTRIN[1-80]; UNCLASSIFIED DRUG; AMINO ACID; CHOLECYSTOKININ B RECEPTOR; COMPLEMENTARY DNA; GASTRIN; MESSENGER RNA; PROTEIN PRECURSOR; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HORMONE ACTION; HORMONE BINDING; IN VITRO STUDY; INTESTINE CELL; INTESTINE EPITHELIUM CELL; LARGE INTESTINE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; TRANSGENIC MOUSE; ANIMAL; BINDING COMPETITION; BIOSYNTHESIS; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; ESCHERICHIA COLI; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE MUCOSA; KINETICS; MASS SPECTROMETRY; METABOLISM; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STIMULATION;

AMINO ACIDS; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA, COMPLEMENTARY; EPITHELIAL CELLS; ESCHERICHIA COLI; FLUORESCENT DYES; GASTRINS; INTESTINAL MUCOSA; KINETICS; MASS SPECTROMETRY; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; PROTEIN PRECURSORS; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STIMULATION, CHEMICAL;

EID: 0037307028     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00351.2002     Document Type: Article

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