Specific anti-viral effects of RNA interference on replication and expression of hepatitis B virus in mice

Chinese Medical Journal

Volumn 118, Issue 16, 2005, Pages 1351-1356

  Wu, Ying ^a   Huang, Ai Long ^a   Tang, Ni ^a   Zhang, Bing Qiang ^a   Lu, Nian Fang ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Gene therapy; Hepatitis B virus; RNA interference

Indexed keywords

GREEN FLUORESCENT PROTEIN; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; MESSENGER RNA; PLASMID DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; BASE PAIRING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE SEQUENCE; GENE TARGETING; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; HEPATITIS B; HEPATITIS B VIRUS; IMMUNOHISTOCHEMISTRY; INJECTION; LIVER HISTOLOGY; MALE; MOUSE; MUTANT; NONHUMAN; PLASMID; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA VECTOR; TAIL; TRANSCRIPTION REGULATION; VEIN; VIRUS DETECTION; VIRUS REPLICATION;

ANIMALS; HEPATITIS B; HEPATITIS B CORE ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; MALE; MICE; MICE, INBRED BALB C; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA, VIRAL; VIRUS REPLICATION;

EID: 24044507587     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Sprinzl MF, Oberwinkler H, Schaller H, et al. Transfer of Hepatitis B Virus Genome by Adenovirus vectors into Cultured Cells and Mice: crossing the species barrier. J Virol 2001;75:5108-5118.
2. Lau DT, Everhart DE, Kleiner Y, et al. Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa. Gastroenterology 1997;113:1660-1667.
3. Niederau CT, Heintges S, Lange G, et al. Long-term follow-up of HbeAg-positive patients treated with interferon alpha for chronic hepatitis B. N Engl J Med 1996;334:1422-1427.
4. Zuckerman AJ, Lavanchy D. Treatment options for chronic hepatitis. Antivirals look promising. BMJ 1999; 319:799-800.
5. Zoulim F. Therapy of chronic hepatitis B virus infection: inhibition of the viral polymerase and other antiviral strategies. Antivir Res 1999;44:1-30.
6. Hammond SM, Bernstein E, Beach D, et al. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 2000;404:293-296.
7. Fire A. RNA-triggered gene silencing. Trends Genet 1999;15:358-363.
8. Sharp PA. RNA interference. Genes Dev 2001;15:485-490.
9. Hammond SM, Caudy AA, Hannon GJ. Post-transcriptional gene silencing by double-stranded RNA. Nat Rev Genet 2001;2:1110-1119.
10. Tuschl T. RNA interference and small interfering RNAs. Chem Biochem 2001;2:239-245.
11. Sayda ME, Jens H, Winfried L, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411:494-498.
12. Tang N, Huang AL, Zhang BQ, et al. Potent and specific inhibition of hepatitis B virus antigen expression by RNA interference. Natl Med J Chin (Chin) 2003; 83:1309-1312.
13. Yang PL, Althage A, Chung J, et al. Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection. Proc Natl Acad Sci U S A 2002;99:13825-13830.
14. Tang N, Huang AL, Zhang BQ, et al. Construction recombinant eukaryotic expression plasmid containing 1.3-fold-overlength genome of HBV and its expression in HepG2 cells. Chin J Hepat(Chin) 2003;1:464-466.
15. Zhang GF, Budker V, Wolff JA. High levels of Foreign Gene Expression in Hepatocytes after Tail Vein Injections of Naked Plasmid DNA. Hum Gene Ther 1999;10:1735-1737.
16. Suzuki T, Takehara T, Ohkawa K, et al. Intravenous injection of naked plasmid DNA encoding hepatitis B virus (HBV) produces HBV and induces humoral immune response in mice. Biochem Biophys Res Commun 2003;300:784-788.
17. Lewis DL, Hagstrom JE, Loomis AG, et al. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 2002;32:107-108.
18. McCAffrey AP, Nakai H, Huang Z, et al. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol 2003;21:639-644.
19. Moolla N, Kew M, Arbuthnot P. Regulatory elements of hepatitis B virus transcription. J Viral Hepat 2002;9:323-332.
20. Birnbaum F, Nassal M. Hepatitis B virus nucleocapsid assembly: primary structure requirements in the core protein. J Virol 1990;64:3319-3330.
21. Bertrand JR, Pottier M, Vekris A, et al. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun 2002;296:1000-1004.
22. Randall G, Grakoui A, Rice CM. Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proc Natl Acad Sci U S A 2003;100:235-240.
23. Yokota T, Sakamoto N, Enomoto N, et al. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO Rep 2003;4:602-608.
24. Wilson JA, Jayasena S, Khvorova A, et al. RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells. Proc Natl Acad Sci U S A 2003;100:2783-2788.
25. Kapadia SB, Brideua-Andersen A, Chisari FV. Interference of hepatitis C virus RNA replication by short interfering RNAs. Proc Natl Acad Sci U S A 2003;100:2014-2018.
26. Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002;20:500-505.
27. Ying C, De CE, Neyts J. Selective inhibition of hepatitis B virus replication by RNA interference. Biochem Biophys Res Commun 2003;309:482-484.
28. Klein C, Bock CT, Wedemeyer H, et al. Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA. Gastroenterology 2003;125:9-18.
29. Hamasaki K, Nakao K, Matsumoto K, et al. Short interfering RNA-directed inhibition of hepatitis B virus replication. FEBS Letters 2003;543:51-54.
30. Shlomai A, Shaul Y. Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology 2003;37:764-770.
31. Yan G, Huang AL, Tang N, et al. Inhibition of survivin expression in liver cancer cells by shRNA. Chin J Hepat (Chin) 2003;11:712-715.