메뉴 건너뛰기




Volumn 64, Issue 3, 2005, Pages 387-393

The production of very-long-chain PUFA biosynthesis in transgenic plants: Towards a sustainable source of fish oils

Author keywords

Desaturase; Elongase; PUFA; Sustainability; Transgenic plants

Indexed keywords

FISH OIL; POLYUNSATURATED FATTY ACID; VERY LONG CHAIN FATTY ACID;

EID: 23844535824     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/PNS2005447     Document Type: Conference Paper
Times cited : (49)

References (51)
  • 1
    • 10044222083 scopus 로고    scopus 로고
    • Biosynthesis of very long chain polyunsaturated fatty acids in transgenic oilseeds: Constraints on their accumulation
    • Abbadi A, Domergue F, Fahl A, Ott C, Bauer J, Napier JA, Welti R, Cirpus P & Heinz E (2004) Biosynthesis of very long chain polyunsaturated fatty acids in transgenic oilseeds: constraints on their accumulation. Plant Cell 16, 2734-2748.
    • (2004) Plant Cell , vol.16 , pp. 2734-2748
    • Abbadi, A.1    Domergue, F.2    Fahl, A.3    Ott, C.4    Bauer, J.5    Napier, J.A.6    Welti, R.7    Cirpus, P.8    Heinz, E.9
  • 5
    • 14744279098 scopus 로고    scopus 로고
    • Biosynthesis and compartmentalisation of triacyglycerol in higher plants
    • Beaudoin F & Napier JA (2004) Biosynthesis and compartmentalisation of triacyglycerol in higher plants. Topics in Current Genetics 6, 267-287.
    • (2004) Topics in Current Genetics , vol.6 , pp. 267-287
    • Beaudoin, F.1    Napier, J.A.2
  • 6
    • 0041952648 scopus 로고    scopus 로고
    • Epidermal anti-inflammatory properties of 5,11,14, 20:3: Effects on mouse ear edema, PGE2 levels in cultured keratinocytes, and PPAR activation
    • Berger A, Monnard I, Baur M, Charbonnet C, Safonova I & Jomard A (2002) Epidermal anti-inflammatory properties of 5,11,14, 20:3: Effects on mouse ear edema, PGE2 levels in cultured keratinocytes, and PPAR activation. Lipids in Health and Disease 1, 1-12.
    • (2002) Lipids in Health and Disease , vol.1 , pp. 1-12
    • Berger, A.1    Monnard, I.2    Baur, M.3    Charbonnet, C.4    Safonova, I.5    Jomard, A.6
  • 7
  • 8
    • 0041315728 scopus 로고    scopus 로고
    • Acyl carriers used as substrates by the desaturases and elongases involved in very long-chain polyunsaturated fatty acids biosynthesis reconstituted in yeast
    • Domergue F, Abbadi A, Ott C, Zank TK, Zahringer U & Heinz E (2003) Acyl carriers used as substrates by the desaturases and elongases involved in very long-chain polyunsaturated fatty acids biosynthesis reconstituted in yeast. Journal of Biological Chemistry 278, 35115-35126.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 35115-35126
    • Domergue, F.1    Abbadi, A.2    Ott, C.3    Zank, T.K.4    Zahringer, U.5    Heinz, E.6
  • 9
    • 0036040288 scopus 로고    scopus 로고
    • Cloning and functional characterization of Phaeodactylum tricornutum front-end desaturases involved in eicosapentaenoic acid biosynthesis
    • Domergue F, Lerchl J, Zahringer U & Heinz E (2002) Cloning and functional characterization of Phaeodactylum tricornutum front-end desaturases involved in eicosapentaenoic acid biosynthesis. European Journal of Biochemistry 269, 4105-4113.
    • (2002) European Journal of Biochemistry , vol.269 , pp. 4105-4113
    • Domergue, F.1    Lerchl, J.2    Zahringer, U.3    Heinz, E.4
  • 12
    • 0038050467 scopus 로고    scopus 로고
    • Genomics and metabolomics as markers for the interaction of diet and health: Lessons from lipids
    • German JB, Roberts MA & Watkins SM (2003) Genomics and metabolomics as markers for the interaction of diet and health: lessons from lipids. Journal of Nutrition 133, 2078S-2083S.
    • (2003) Journal of Nutrition , vol.133
    • German, J.B.1    Roberts, M.A.2    Watkins, S.M.3
  • 13
    • 0141516449 scopus 로고    scopus 로고
    • Role of long-chain polyunsaturated fatty acids in infant nutrition
    • Gil A, Ramirez M & Gil M (2003) Role of long-chain polyunsaturated fatty acids in infant nutrition. European Journal of Clinical Nutrition 57, Suppl. 1, S31-S34.
    • (2003) European Journal of Clinical Nutrition , vol.57 , Issue.SUPPL. 1
    • Gil, A.1    Ramirez, M.2    Gil, M.3
  • 14
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin e after myocardial infarction: Results of the GISSI-Prevenzione trial
    • Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • GISSI-Prevenzione Investigators (1999) Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354, 447-455.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 15
    • 0242442479 scopus 로고    scopus 로고
    • Diet, nutrition, and cancer prevention: The postgenomic era
    • Go VL, Butrum RR & Wong DA (2003) Diet, nutrition, and cancer prevention: the postgenomic era. Journal of Nutrition 133, 3830S-3836S.
    • (2003) Journal of Nutrition , vol.133
    • Go, V.L.1    Butrum, R.R.2    Wong, D.A.3
  • 16
    • 4444332519 scopus 로고    scopus 로고
    • The use of very long chain polyunsaturated fatty acids to ameliorate Metabolic Syndrome: Transgenic plants as an alternative sustainable source to fish oils
    • Graham IA, Cirpus P, Rein D & Napier JA (2004) The use of very long chain polyunsaturated fatty acids to ameliorate Metabolic Syndrome: transgenic plants as an alternative sustainable source to fish oils. Nutrition Bulletin 29, 228-233.
    • (2004) Nutrition Bulletin , vol.29 , pp. 228-233
    • Graham, I.A.1    Cirpus, P.2    Rein, D.3    Napier, J.A.4
  • 17
    • 2542643941 scopus 로고    scopus 로고
    • From alpha to omega-producing essential fatty acids in plants
    • Green AG (2004) From alpha to omega-producing essential fatty acids in plants. Nature Biotechnology 22, 680-682.
    • (2004) Nature Biotechnology , vol.22 , pp. 680-682
    • Green, A.G.1
  • 20
    • 0042786559 scopus 로고    scopus 로고
    • Genetics of macular dystrophies and implications for age-related macular degeneration
    • Klaver CC & Allikmets R (2003) Genetics of macular dystrophies and implications for age-related macular degeneration. Developments in Ophthalmology 37, 155-169.
    • (2003) Developments in Ophthalmology , vol.37 , pp. 155-169
    • Klaver, C.C.1    Allikmets, R.2
  • 23
    • 0035854452 scopus 로고    scopus 로고
    • Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes
    • Metz JG, Roessler P, Facciotti D, Levering C, Dittrich F, Lassner M et al. (2001) Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes. Science 293, 290-293.
    • (2001) Science , vol.293 , pp. 290-293
    • Metz, J.G.1    Roessler, P.2    Facciotti, D.3    Levering, C.4    Dittrich, F.5    Lassner, M.6
  • 24
    • 10044269845 scopus 로고    scopus 로고
    • Novel fatty acid elongases and their use for the reconstitution of docosahexaenoic acid biosynthesis
    • Meyer A, Kirsch H, Domergue F, Abbadi A, Sperling P, Bauer J et al. (2004) Novel fatty acid elongases and their use for the reconstitution of docosahexaenoic acid biosynthesis. Journal of Lipid Research 45, 1899-909.
    • (2004) Journal of Lipid Research , vol.45 , pp. 1899-1909
    • Meyer, A.1    Kirsch, H.2    Domergue, F.3    Abbadi, A.4    Sperling, P.5    Bauer, J.6
  • 25
    • 0032202154 scopus 로고    scopus 로고
    • Accumulation of very-long-chain fatty acids in membrane glycerolipids is associated with dramatic alterations in plant morphology
    • Millar AA, Wrischer M & Kunst L (1998) Accumulation of very-long-chain fatty acids in membrane glycerolipids is associated with dramatic alterations in plant morphology. Plant Cell 10, 1889-1902.
    • (1998) Plant Cell , vol.10 , pp. 1889-1902
    • Millar, A.A.1    Wrischer, M.2    Kunst, L.3
  • 26
    • 0033945077 scopus 로고    scopus 로고
    • Occurrence of a novel cannabimimetic molecule 2-sciadonoylglycerol (2-eicosa-5′,11′,14′-trienoylglycerol) in the umbrella pine Sciadopitys verticillata seeds
    • Nakane S, Tanaka T, Satouchi K, Kobayashi Y, Waku K & Sugiura T (2000) Occurrence of a novel cannabimimetic molecule 2-sciadonoylglycerol (2-eicosa-5′,11′,14′-trienoylglycerol) in the umbrella pine Sciadopitys verticillata seeds. Biological and Pharmaceutical Bulletin 23, 758-761.
    • (2000) Biological and Pharmaceutical Bulletin , vol.23 , pp. 758-761
    • Nakane, S.1    Tanaka, T.2    Satouchi, K.3    Kobayashi, Y.4    Waku, K.5    Sugiura, T.6
  • 27
    • 0036483897 scopus 로고    scopus 로고
    • Plumbing the depths of PUFA biosynthesis: A novel polyketide synthase-like pathway from marine organisms
    • Napier JA (2002) Plumbing the depths of PUFA biosynthesis: a novel polyketide synthase-like pathway from marine organisms. Trends in Plant Science 7, 51-54.
    • (2002) Trends in Plant Science , vol.7 , pp. 51-54
    • Napier, J.A.1
  • 29
    • 12344328374 scopus 로고    scopus 로고
    • Progress towards the production of polyunsaturated fatty acids in transgenic plants
    • Napier JA, Sayanova O, Qi B & Lazarus CM (2004) Progress towards the production of polyunsaturated fatty acids in transgenic plants. Lipids 39, 1067-1075.
    • (2004) Lipids , vol.39 , pp. 1067-1075
    • Napier, J.A.1    Sayanova, O.2    Qi, B.3    Lazarus, C.M.4
  • 30
    • 1542300237 scopus 로고    scopus 로고
    • The metabolic syndrome
    • Nugent AP (2004) The metabolic syndrome. Nutrition Bulletin 29, 36-43.
    • (2004) Nutrition Bulletin , vol.29 , pp. 36-43
    • Nugent, A.P.1
  • 31
    • 0038117772 scopus 로고    scopus 로고
    • Biotechnological approaches to modify rapeseed oil composition for applications in aquaculture
    • Opsahl-Ferstad H-G, Rudi H, Ruyter B & Refstie S (2003) Biotechnological approaches to modify rapeseed oil composition for applications in aquaculture. Plant Science 165, 349-357.
    • (2003) Plant Science , vol.165 , pp. 349-357
    • Opsahl-Ferstad, H.-G.1    Rudi, H.2    Ruyter, B.3    Refstie, S.4
  • 34
    • 10044262097 scopus 로고    scopus 로고
    • Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid, eicosapentaenoic acid (EPA), to docosahexaenoic acid (DHA)
    • Pereira SL, Leonard AE, Huang YS, Chuang LT & Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid, eicosapentaenoic acid (EPA), to docosahexaenoic acid (DHA). Biochemical Journal 384, 357-366.
    • (2004) Biochemical Journal , vol.384 , pp. 357-366
    • Pereira, S.L.1    Leonard, A.E.2    Huang, Y.S.3    Chuang, L.T.4    Mukerji, P.5
  • 35
    • 0037116606 scopus 로고    scopus 로고
    • Identification of a cDNA encoding a novel CJapanese source18-Δ9 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga, Isochrysis galbana
    • Qi B, Beaudoin F, Fraser T, Stobart AK, Napier JA & Lazarus CM (2002) Identification of a cDNA encoding a novel CJapanese source18-Δ9 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga, Isochrysis galbana. FEBS Letters 510, 159-165.
    • (2002) FEBS Letters , vol.510 , pp. 159-165
    • Qi, B.1    Beaudoin, F.2    Fraser, T.3    Stobart, A.K.4    Napier, J.A.5    Lazarus, C.M.6
  • 37
    • 0037321753 scopus 로고    scopus 로고
    • Biosynthesis of docosahexaenoic acid (DHA, 22:6-4. 7,10,13,16,19): Two distinct pathways
    • Qiu X (2003) Biosynthesis of docosahexaenoic acid (DHA, 22:6-4. 7,10,13,16,19): two distinct pathways. Prostaglandins, Leukotrienes, and Essential Fatty Acids 68, 181-186.
    • (2003) Prostaglandins, Leukotrienes, and Essential Fatty Acids , vol.68 , pp. 181-186
    • Qiu, X.1
  • 38
    • 0035943661 scopus 로고    scopus 로고
    • Identification of a Δ4 fatty acid desaturase from Thraustochytrium sp. involved in the biosynthesis of docosahexanoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea
    • Qiu X, Hong H & MacKenzie SL (2001) Identification of a Δ4 fatty acid desaturase from Thraustochytrium sp. involved in the biosynthesis of docosahexanoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea. Journal of Biological Chemistry 276, 31561-31566.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 31561-31566
    • Qiu, X.1    Hong, H.2    MacKenzie, S.L.3
  • 39
    • 0032791693 scopus 로고    scopus 로고
    • Development of farmed fish: A nutritionally necessary alternative to meat
    • Sargent JR & Tacon AG (1999) Development of farmed fish: a nutritionally necessary alternative to meat. Proceedings of the Nutrition Society 58, 377-383.
    • (1999) Proceedings of the Nutrition Society , vol.58 , pp. 377-383
    • Sargent, J.R.1    Tacon, A.G.2
  • 40
    • 0742324895 scopus 로고    scopus 로고
    • Eicosapentaenoic acid: Biosynthetic routes and the potential for synthesis in transgenic plants
    • Sayanova O & Napier JA (2004) Eicosapentaenoic acid: biosynthetic routes and the potential for synthesis in transgenic plants. Phytochemistry 65, 147-158.
    • (2004) Phytochemistry , vol.65 , pp. 147-158
    • Sayanova, O.1    Napier, J.A.2
  • 41
    • 0036955891 scopus 로고    scopus 로고
    • SNP alleles in human disease and evolution
    • Shastry BS (2002) SNP alleles in human disease and evolution. Journal of Human Genetics 47, 561-566.
    • (2002) Journal of Human Genetics , vol.47 , pp. 561-566
    • Shastry, B.S.1
  • 43
    • 0034221273 scopus 로고    scopus 로고
    • Human requirement for n-3 polyunsaturated fatty acids
    • Simopoulos AP (2000) Human requirement for n-3 polyunsaturated fatty acids. Poultry Science 79, 961-970.
    • (2000) Poultry Science , vol.79 , pp. 961-970
    • Simopoulos, A.P.1
  • 45
    • 0036338519 scopus 로고    scopus 로고
    • Metabolic engineering of fatty acid biosynthesis in plants
    • Thelen JJ & Ohlrogge JB (2002) Metabolic engineering of fatty acid biosynthesis in plants. Metabolic Engineering 4, 12-21.
    • (2002) Metabolic Engineering , vol.4 , pp. 12-21
    • Thelen, J.J.1    Ohlrogge, J.B.2
  • 46
    • 0032984786 scopus 로고    scopus 로고
    • Fatty acid metabolism in marine fish: Low activity of fatty acyl Δ5 desaturation in gilthead sea bream (Sparus aurata) cells
    • Tocher DR & Ghioni C (1999) Fatty acid metabolism in marine fish: low activity of fatty acyl Δ5 desaturation in gilthead sea bream (Sparus aurata) cells. Lipids 34, 433-440.
    • (1999) Lipids , vol.34 , pp. 433-440
    • Tocher, D.R.1    Ghioni, C.2
  • 47
  • 48
    • 0037645445 scopus 로고    scopus 로고
    • The role of omega-3 fatty acids in cardiovascular disease
    • von Schacky C (2003) The role of omega-3 fatty acids in cardiovascular disease. Current Atherosclerosis Reports 5, 139-145.
    • (2003) Current Atherosclerosis Reports , vol.5 , pp. 139-145
    • Von Schacky, C.1
  • 49
    • 0033561806 scopus 로고    scopus 로고
    • The Δ8-desaturase of Euglena gracilis: An alternate pathway for synthesis of 20-carbon polyunsaturated fatty acids
    • Wallis JG & Browse J (1999) The Δ8-desaturase of Euglena gracilis: an alternate pathway for synthesis of 20-carbon polyunsaturated fatty acids. Archives of Biochemistry and Biophysics 365, 307-316.
    • (1999) Archives of Biochemistry and Biophysics , vol.365 , pp. 307-316
    • Wallis, J.G.1    Browse, J.2
  • 50
    • 0036710533 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid synthesis: What will they think of next?
    • Wallis JG, Watts JL & Browse J (2002) Polyunsaturated fatty acid synthesis: what will they think of next? Trends in Biochemical Sciences 27, 467-470.
    • (2002) Trends in Biochemical Sciences , vol.27 , pp. 467-470
    • Wallis, J.G.1    Watts, J.L.2    Browse, J.3
  • 51
    • 0141541805 scopus 로고    scopus 로고
    • Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution
    • Zhao Z, Fu YX, Hewett-Emmett D & Boerwinkle E (2003) Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution. Gene 312, 207-213.
    • (2003) Gene , vol.312 , pp. 207-213
    • Zhao, Z.1    Fu, Y.X.2    Hewett-Emmett, D.3    Boerwinkle, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.