Lipids modulate ligand binding to sulphonylurea receptors

British Journal of Pharmacology

Volumn 145, Issue 7, 2005, Pages 907-915

  Klein, Alexander ^a   Lichtenberg, Jochen ^a   Stephan, Damian ^a   Quast, Ulrich ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b Department of Pharmacology   (Germany)

Author keywords

Glibenclamide; Inhibition of ligand binding to SUR by lipids; Interaction of lipids with SUR; Lipids; Oleoyl CoA; P1075; Sulphonylurea receptors (SURs)

Indexed keywords

2 CYANO 1 (1,1 DIMETHYLPROPYL) 3 (3 PYRIDYL)GUANIDINE; DIOLEYLGLYCEROL SUCCINYLNITROLOACETIC ACID; FATTY ACID DERIVATIVE; GLIBENCLAMIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; MALONYL COENZYME A; OLEIC ACID; OLEOYL COENZYME A; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLYLYSINE; RADIOLIGAND; RECEPTOR SUBTYPE; SULFONYLUREA; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR 1; SULFONYLUREA RECEPTOR 2A; SULFONYLUREA RECEPTOR 2B; UNCLASSIFIED DRUG;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ACYL COENZYME A; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GLYBURIDE; GUANIDINES; HUMANS; LYSINE; OLEIC ACIDS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POLYLYSINE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRIDINES; RECEPTORS, DRUG; SUCCINATES; TRANSFECTION;

EID: 23744467972     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706252     Document Type: Article

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