Polyelectrolyte-protein complexes

Current Opinion in Colloid and Interface Science

Volumn 10, Issue 1-2, 2005, Pages 52-78

  Cooper, C L ^a   Dubin, P L ^a   Kayitmazer, A B ^a   Turksen, S ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; COLLOIDS; COMPLEXATION; COMPUTER SIMULATION; MATHEMATICAL MODELS; PROTEINS;

BIOCHEMICAL INTERESTS; PAROCHIAL INTERACTIONS; POLYELECTROLYTE-PROTEIN COMPLEXES; SEMI-SYNTHETIC SYSTEMS;

POLYELECTROLYTES;

POLYELECTROLYTE; SILICON DIOXIDE;

AFFINITY CHROMATOGRAPHY; ANISOTROPY; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; BIOSENSOR; BLEACHING; CALORIMETRY; CAPILLARY ELECTROPHORESIS; CATALYST; CIRCULAR DICHROISM; COACERVATION; COMPLEX FORMATION; CRYSTAL; DIFFERENTIAL SCANNING CALORIMETRY; ELECTRON MICROSCOPY; ELECTROPHORESIS; ENZYME IMMOBILIZATION; FLOW KINETICS; FLUORESCENCE; GEL PERMEATION CHROMATOGRAPHY; HYDROGEL; HYDROPHOBICITY; INFRARED SPECTROSCOPY; ISOTHERMAL TITRATION CALORIMETRY; LIGHT SCATTERING; MICROENCAPSULATION; MICROSCOPY; MONTE CARLO METHOD; NEUTRON; PH; POTENTIOMETRY; PROTEIN INTERACTION; QUANTUM THEORY; RADIATION SCATTERING; REFLECTOMETRY; REVIEW; SEPARATION TECHNIQUE; SURFACE PLASMON RESONANCE; TITRIMETRY; TURBIDIMETRY;

EID: 23744467411     PISSN: 13590294     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cocis.2005.05.007     Document Type: Review

References (117)

1. H. Morawetz, and W.L. Hughes Jr. Interaction of proteins with synthetic polyelectrolytes: I. Complexing of bovine serum albumin J Phys Chem 56 1952 64 69
2. M. Sternber, and D. Hershber Separation of proteins with polyacrylic acids Biochim Biophys Acta 342 1974 195 206
3. H. Morawetz, and H. Sage The effect of poly(acrylic acid) on the tryptic digestion of hemoglobin Arch Biochem Biophys 56 1955 103 109
4. N.I. Larionova, L.Y. Unksova, V.A. Mironov, I.Y. Sakharov, N.F. Kazanskaya, and I.V. Berezin Study of the complex-formation between soluble carboxymethyl ethers of polysaccharides and proteins Vysokomol Soedin, Ser A 23 1981 1823 1829
5. J.L. Xia, and P.L. Dubin Protein-polyelectrolyte complexes P.L. Dubin Bock Davis Schulz Theis Macromolecular Complexes in Chemistry and Biology 1994 Springer-Verlag Berlin Heidelberg 247 271
6. C. Tribet Complexation between amphiphilic polyelectrolytes and proteins: from necklaces to gels T. Radeva Physical Chemistry of Polyelectrolytes 2001 Marcel Dekker Inc. New York A perceptive and thorough review that goes considerably beyond the limitations of its title.
7. V.B. Tolstoguzov Protein-polysaccharide interactions Food Sci Technol (NY) 80 1997 171 198
8. J.L. Doublier, C. Garnier, D. Renard, and C. Sanchez Protein- polysaccharide interactions Curr Opin Colloid Interface Sci 5 2000 202 214
9. S.L. Turgeon, M. Beaulieu, C. Schmitt, and C. Sanchez Protein-polysaccharide interactions: phase-ordering kinetics, thermodynamic and structural aspects Curr Opin Colloid Interface Sci 8 2003 401 414
10. E. Dickinson Stability and rheological implications of electrostatic milk protein-polysaccharide interactions Trends Food Sci Technol 9 1998 347 354
11. T. Matsudo, K. Ogawa, and E. Kokufuta Complex formation of protein with different water-soluble synthetic polymers Biomacromolecules 4 2003 1794 1799
12. E. Kokufuta Complexation of proteins with polyelectrolytes in a salt-free system and biochemical characteristics of the resulting complexes P.L. Dubin J. Bock R.M. Davies D.N. Schulz C. Thies Macromolecular Complexes in Chemistry and Biology 1994 Springer-Verlag Berlin Heidelberg 301 325
13. V.A. Kabanov, V.B. Skobeleva, V.B. Rogacheva, and A.B. Zezin Sorption of proteins by slightly cross-linked polyelectrolyte hydrogels: kinetics and mechanism J Phys Chem, B 108 2004 1485 1490
14. S. Rosenfeldt, A. Wittemann, M. Ballauff, E. Breininger, J. Bolze, and N. Dingenouts Interaction of proteins with spherical polyelectrolyte brushes in solution as studied by small-angle X-ray scattering Phys Rev E Stat Nonlin Soft Matter Phys 70 2004 061403-1 061403-10
15. M.M.O. Eleya, and S.L. Turgeon The effects of pH on the rheology of b-lactoglobulin/k-carrageenan mixed gels Food Hydrocoll 14 2000 245 251
16. C. Gergely, S. Bahi, B. Szalontai, H. Flores, P. Schaaf, and J.C. Voegel Human serum albumin self-assembly on weak polyelectrolyte multilayer films structurally modified by pH changes Langmuir 20 2004 5575 5582
17. M.K. Ram, P. Bertoncello, H. Ding, S. Paddeu, and C. Nicolini Cholesterol biosensors prepared by layer-by-layer technique Biosens Bioelectron 16 2001 849 856
18. C. Czeslik, R. Jansen, M. Ballauff, A. Wittemann, C.A. Royer, E. Gratton, and T. Hazlett Mechanism of protein binding to spherical polyelectrolyte brushes studied in situ using two-photon excitation fluorescence fluctuation spectroscopy Phys Rev E 69 2004
19. T. Pihlajamaa, H. Lankinen, J. Ylostalo, L. Valmu, J. Jaalinoja, and F. Zaucke Characterization of recombinant amino-terminal NC4 domain of human collagen IX - interaction with glycosaminoglycans and cartilage oligomeric matrix protein J Biol Chem 279 2004 24265 24273 The heparin binding ability of the N-terminal NC4 domain of collagen IX was attributed to its high isoelectronic point and its location within the collagen fibril. This insightful article discusses the application of several techniques including surface plasmon resonance, circular dichroism, electron microscopy, and MALDI-TOF mass spectrometry to elucidate the nature of interaction between collagen IX and heparin and its possible role in maintaining the integrity of the extracellular matrix.
20. D.J. Burgess Complex coacervation: microcapsule formation P.L. Dubin Bock Davis Schulz Thies Macromolecular Complexes in Chemistry and Biology 1994 Springer-Verlag Berlin 285 300 A valuable early review on protein- polyelectrolyte complex coacervation and microencapsulation with an application on albumin/acacia system. The albumin/acacia coacervate system was found to be stable with respect to aging, temperature, pH, ionic strength, and dilution with crosslinking agent.
21. Y. Lvov, K. Ariga, I. Ichinose, and T. Kunitake Assembly of multicomponent protein films by means of electrostatic layer-by-layer adsorption J Am Chem Soc 117 1995 6117 6123 A heavily cited, detailed study on assembly of multiple proteins embedded in polyelectrolyte multilayers. It provides protein multilayer architectures according to their specific biological activities.
22. F. Caruso, and H. Mohwald Protein multilayer formation on colloids through a stepwise self-assembly technique J Am Chem Soc 121 1999 6039 6046 An outstanding paper showing that layer-by-layer self assembly technique can be used to coat colloidal particles with polyelectrolyte-protein multilayers. Results indicate protein-polyelectrolyte multilayer assembly proceeds in a manner similar to that on planar surfaces. Experimental techniques applicable to protein-polyelectrolyte multilayers on spherical surfaces are described.
23. V. Ducel, J. Richard, P. Saulnier, Y. Popineau, and F. Boury Evidence and characterization of complex coacervates containing plant proteins: application to the microencapsulation of oil droplets Colloids Surf, A Physicochem Eng Asp 232 2004 239 247
24. G. Mekhloufi, C. Sanchez, D. Renard, S. Guillemin, and J. Hardy pH-induced structural transitions during complexation and coacervation of beta-lactoglobulin and acacia gum Langmuir 21 2005 386 394
25. M. Houska, and E. Brynda Interactions of proteins with polyelectrolytes at solid/liquid interfaces: sequential adsorption of albumin and heparin J. Colloid Interface Sci. 188 1997 243 250 Applications of diffusing wave spectroscopy (DWS) and laser scanning confocal microscopy (LSCM) to coacervates. One can find both theoretical and experimental information on both of these techniques, which are recently getting more attention in protein-polyelectrolyte systems.
26. K. Anikin, C. Röcker, A. Wittemann, J. Wiedenmann, M. Ballauff, and U. Nienhaus Polyelectrolyte-mediated protein adsorption: fluorescent protein binding to individual polyelectrolyte nanospheres J Phys Chem B, Lett 109 2005 5418 5420
27. C. Czeslik Factors ruling protein adsorption Z Phys Chem-Int J Res Phys Chem Chem Phys 218 2004 771 801
28. S. Rosenfeldt, A. Wittemann, M. Ballauff, E. Breininger, J. Bolze, and N. Dingenouts Interaction of proteins with spherical polyelectrolyte brushes in solution as studied by small-angle x-ray scattering Phys Rev E 70 2004
29. Y.F. Wang, and P.L. Dubin Protein binding on polyelectrolyte-treated glass - effect of structure of adsorbed polyelectrolyte J Chromatogr A 808 1998 61 70
30. E. Seyrek, P.L. Dubin, C. Tribet, and E.A. Gamble Ionic strength dependence of protein-polyelectrolyte interactions Biomacromolecules 4 2003 273 282
31. H.B. Bohidar, P.L. Dubin, P.R. Majhi, C. Tribet, and W. Jaeger Effects of protein-polyelectrolyte affinity and polyelectrolyte molecular weight on dynamic properties of bovine serum albumin-poly(diallyldimethylammonium chloride) coacervates Biomacromolecules 6 2005 1573 1585 Dynamics of BSA-PDADMAC coacervates prepared at different pH and I were investigated with dynamic light scattering and rheology experiments. The authors have proposed two models to explain the nanostructure and dynamics of coacervates; namely, a dispersion of microphases and a semidilute matrix of polymer-protein complexes.
32. J.L. Xia, H.W. Zhang, D.R. Rigsbee, P.L. Dubin, and T. Shaikh Structural elucidation of soluble polyelectrolyte-micelle complexes - intrapolymer vs. interpolymer association Macromolecules 26 1993 2759 2766
33. A. Tsuboi, T. Izumi, M. Hirata, J.L. Xia, P.L. Dubin, and E. Kokufuta Complexation of proteins with a strong polyanion in an aqueous salt-free system Langmuir 12 1996 6295 6303
34. L. Richert, P. Lavalle, D. Vautier, B. Senger, J.F. Stoltz, P. Schaaf, and P. Schaaf Cell interactions with polyelectrolyte multilayer films Biomacromolecules 3 2002 1170 1178 Small angle X-ray scattering (SAXS) is used to study the interaction of proteins with spherical polyelectrolyte brushes. The major finding is the entry of the protein into the brush layer.
35. J.L. Xia, P.L. Dubin, E. Kokufuta, H. Havel, and B.B. Muhoberac Light scattering, CD, and ligand binding studies of ferrihemoglobin-polyelectrolyte complexes Biopolymers 50 1999 153 161
36. D.J. Burgess, K.K. Kwok, and P.T. Megremis Characterization of albumin-acacia complex coacervation J Pharm Pharmacol 43 1991 232 236
37. F. Weinbreck, H.S. Rollema, R.H. Tromp, and C.G. de Kruif Diffusivity of whey protein and gum arabic in their coacervates Langmuir 20 2004 6389 6395
38. L.E. Bromberg Interactions among proteins and hydrophobically modified polyelectrolytes J Pharm Pharmacol 53 2001 541 547
39. H.L. Jiang, and K.J. Zhu Polyanion/gelatin complexes as pH-sensitive gels for controlled protein J Appl Polym Sci 80 2001 1416 1425
40. M. van de Weert, M.B. Andersen, and S. Frokjaer Complex coacervation of lysozyme and heparin: complex characterization and protein stability Pharm Res 21 2004 2354 2359
41. A. Wittemann, and M. Ballauff Secondary structure analysis of proteins embedded in spherical polyelectrolyte brushes by FT-IR spectroscopy Anal Chem 76 2004 2813 2819
42. M. Muller, T. Rieser, P.L. Dubin, and K. Lunkwitz Selective interaction between proteins and the outermost surface of polyelectrolyte multilayers: influence of the polyanion type, pH and salt Macromol Rapid Commun 22 2001 390 395
43. P. Schwinte, J.C. Voegel, C. Picart, Y. Haikel, P. Schaaf, and B. Szalontai Stabilizing effects of various polyelectrolyte multilayer films on the structure of adsorbed/embedded fibrinogen molecules: an ATR-FTIR study J Phys Chem, B 105 2001 11906 11916 A very useful article that compares embedded and terminally adsorbed proteins in multilayers. Structural changes of fibrinogen at both room and elevated temperatures were studied as a consequence of protein location in the polyelectrolyte multilayers. The application of optical waveguide lightmode spectroscopy (OWLS) to multilayer assemblies is described.
44. A. Teramoto, Y. Takagi, A. Hachimori, and K. Abe Interaction of albumin with polysaccharides containing ionic groups Polym Adv Technol 10 1999 681 686
45. J. Gong, P. Yao, H.W. Duan, M. Jiang, S.H. Gu, and L. Chunyu Structural transformation of cytochrome c and apo cytochrome c induced by sulfonated polystyrene Biomacromolecules 4 2003 1293 1300
46. K.W., Mattison, Ph.D. Thesis, Purdue Univ., Indianapolis, IN, 1999.
47. Y.P. Wen, and P.L. Dubin Potentiometric studies of the interaction of bovine serum albumin and poly(dimethyldiallylammonium chloride) Macromolecules 30 1997 7856 7861
48. O.N. Ivinova, V.A. Izumrudov, V.I. Muronetz, I.Y. Galaev, and B. Mattiasson Influence of complexing polyanions on the thermostability of basic proteins Macromol Biosci 3 2003 210 215
49. M. Girard, S.L. Turgeon, and S.F. Gauthier Thermodynamic parameters of beta-lactoglobulin-pectin complexes assessed by isothermal titration calorimetry J Agric Food Chem 51 2003 4450 4455 Isothermal titration calorimetry was used to determine the thermodynamic parameters of lactoglobulin/pectin complexes. Soluble complex formation was found to be enthalpically driven while coacervate formation was driven by enthalpic and entropic factors.
50. A.K. Andrianov, A. Marin, and B.E. Roberts Polyphosphazene polyelectrolytes: a link between the formation of noncovalent complexes with antigenic proteins and immunostimulating activity Biomacromolecules 6 2005 1375 1379
51. Y.F. Wang, J.Y. Gao, and P.L. Dubin Protein separation via polyelectrolyte coacervation: selectivity and efficiency Biotechnol Prog 12 1996 356 362
52. P.J. Hogg, C.M. Jackson, and D.J. Winzor Use of quantitative affinity-chromatography for characterizing high-affinity interactions - binding of heparin to antithrombin-Iii Anal Biochem 192 1991 303 311
53. J.Y. Gao, P.L. Dubin, and B.B. Muhoberac Measurement of the binding of proteins to polyelectrolytes by frontal analysis continuous capillary electrophoresis Anal Chem 69 1997 2945 2951 Introduces FACCE for measuring polyelectrolyte-protein binding isotherms, and obtaining thereby binding constants and binding site size.
54. M. Girard, S.L. Turgeon, and S.F. Gauthier Quantification of the interactions between beta-lactoglobulin and pectin through capillary electrophoresis analysis J Agric Food Chem 51 2003 6043 6049
55. J.D. San Antonio, and A.D. Lander Affinity coelectrophoresis of proteoglycan-protein complexes Methods Mol Biol (Clifton NJ) 171 2001 401 414
56. M.E. Herndon, C.S. Stipp, and A.D. Lander Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: assessment of selectivity, heterogeneity and the participation of core proteins in binding Glycobiology 9 1999 143 155 Differences in relative binding affinities, measured by affinity coelectrophoresis (ACE) for heparan sulfate and heparin that could not be explained solely by charge content. Stronger binding was observed for cognates than for non-cognates, although exogenous heparin bound more strongly to the proteins than did their cognate GAGs.
57. G. Ladam, P. Schaaf, F.J.G. Cuisinier, G. Decher, and J.C. Voegel Protein adsorption onto auto-assembled polyelectrolyte films Langmuir 17 2001 878 882 Surface plasmon resonance (SPR) was used to study the adsorption kinetics of several proteins in TAPPEM systems. A useful description of SPR for protein-polyelectrolyte systems.
58. C. Czeslik, G. Jackler, R. Steitz, and H.H. von Grunberg Protein binding to like-charged polyelectrolyte brushes by counterion evaporation J Phys Chem, B 108 2004 13395 13402 The major finding is that protein adsorption onto planar brushes is very similar to corresponding behavior of the more commonly studied spherical brushes.
59. L. Szyk, P. Schaaf, C. Gergely, J.C. Voegel, and B. Tinland Lateral mobility of proteins adsorbed on or embedded in polyelectrolyte multilayers Langmuir 17 2001 6248 6253 Expert interpretation of results from multiple techniques illuminates without speculation the challenging subject of protein diffusivity in multilayers. The diffusion constant of the protein was measured by fluorescent photobleaching recovery, which can be a very useful tool in protein-polyelectrolyte complexation research.
60. A.M. Yu, and F. Caruso Thin films of polyelectrolyte-encapsulated catalase microcrystals for biosensing Anal Chem 75 2003 3031 3037
61. M. Hernaiz, J. Liu, R.D. Rosenberg, and R.J. Linhardt Enzymatic modification of heparan sulfate on a biochip promotes its interaction with antithrombin III Biochem Biophys Biol Res Commun 276 2000 292 297 An entrée into the literature on glycosaminoglycans from one of the most productive chemists in this field.
62. F. Caruso, K. Niikura, D.N. Furlong, and Y. Okahata Assembly of alternating polyelectrolyte and protein multilayer films for immunosensing Langmuir 13 1997 3427 3433 Surface plasmon resonance (SPR) and the quartz crystal microbalance (QCM) were used to monitor assembly of multilayers films prepared for immunosensing. The article may be useful for researchers interested in application of these techniques to protein-polyelectrolyte multilayers.
63. R. Borrega, C. Tribet, and R. Audebert Reversible gelation in hydrophobic polyelectrolyte/protein mixtures: an example of cross-links between soft and hard colloids Macromolecules 32 1999 7798 7806
64. F. Weinbreck, and R.H.W. Wientjes Rheological properties of whey protein/gum arabic coacervates J Rheol 48 2004 1215 1228
65. T. Selzer, S. Albeck, and G. Schreiber Rational design of faster associating and tighter binding protein complexes Nat Struct Biol 7 2000 537 541 One of a series of papers that demonstrates to biochemists the potential of Delphi.
66. J.Y. Gao, and P.L. Dubin Binding of proteins to copolymers of varying hydrophobicity Biopolymers 49 1999 185 193
67. D. Takahashi, Y. Kubota, K. Kokai, T. Izumi, M. Hirata, and E. Kokufuta Effects of surface charge distribution of proteins in their complexation with polyelectrolytes in an aqueous salt-free system Langmuir 16 2000 3133 3140
68. M. Skepoe, and P. Linse Complexation, phase separation, and redissolution in polyelectrolyte-macroion solutions Macromolecules 36 2003 508 519
69. M. Jonsson, and P. Linse Polyelectrolyte-macroion complexation: II. Effect of chain flexibility J Chem Phys 115 2001 10975 10985
70. T. Wallin, and P. Linse Monte Carlo simulations of polyelectrolytes at charged micelles: 1. Effects of chain flexibility Langmuir 12 1996 305 314 A seminal paper with evocative MC snapshots, providing a physical sense of possible structures on the nm scale of the association of charged spheres with oppositely charged polyelectrolytes. Generically useful notwithstanding the apparent emphasis on surfactant binding.
71. S. Stoll, and P. Chodanowski Polyelectrolyte adsorption on an oppositely charged spherical particle. Chain rigidity effects Macromolecules 35 2002 9556 9562
72. G.S. Manning Simple model for the binding of a polyelectrolyte to an oppositely charged curved surface J Phys Chem, B 107 2003 11485 11490
73. A.B. Kayitmazer, E. Seyrek, P.L. Dubin, and B.A. Staggemeier Influence of chain stiffness on the interaction of polyelectrolytes with oppositely charged micelles and proteins J Phys Chem, B 107 2003 8158 8165
74. T. Hattori, S. Bat-Aldar, R. Kato, H. Bohidar, and P.L. Dubin Characterization of polyanion-protein complexes by frontal analysis continuous capillary electrophoresis and small angle neutron scattering: effect of polyanion flexibility Anal. Biochem. 342 2005 229 236
75. A.B. Kayitmazer, D. Shaw, and P.L. Dubin The role of polyelectrolyte persistence length in the binding of oppositely charged micelles, dendrimers and protein to chitosan and poly(diallydimethylammonium chloride) Macromolecules 38 2005 5198 5204
76. T. Hattori, K. Kimura, E. Seyrek, and P.L. Dubin Binding of bovine serum albumin to heparin determined by turbidimetric titration and frontal analysis continuous capillary electrophoresis Anal Biochem 295 2001 158 167
77. K.R. Grymonpre, B.A. Staggemeier, P.L. Dubin, and K.W. Mattison Identification by integrated computer modeling and light scattering studies of an electrostatic serum albumin-hyaluronic acid binding site Biomacromolecules 2 2001 422 429
78. W. Rocchia, E. Alexov, and B. Honig Extending the applicability of the nonlinear Poisson-Boltzmann equation: multiple dielectric constants and multivalent ions J Phys Chem, B 105 2001 6507 6514
79. D. Takahashi, Y. Kubota, K. Kokai, T. Izumi, M. Hirata, and E. Kokufuta Effects of surface charge distribution of proteins in their complexation with polyelectrolytes in an aqueous salt-free system Langmuir 16 2000 3133 3140
80. W.J. Wu, B. Vrhovski, and A.S. Weiss Glycosaminoglycans mediate the coacervation of human tropoelastin through dominant charge interactions involving lysine side chains J Biol Chem 274 1999 21719 21724
81. V.A. Kabanov Physicochemical basis and the prospects of using soluble interpolyelectrolyte complexes Polym Sci USSR 36 1994 143 156
82. X.H. Feng, P.L. Dubin, H.W. Zhang, G.F. Kirton, P. Bahadur, and J. Parotte Critical conditions for binding of dimethyldodecylamine oxide micelles to polyanions of variable charge density Macromolecules 34 2001 6373 6379
83. C. Cooper, A. Goulding, A.B. Kayitmazer, and P.L. Dubin Charge pattern recognition in interaction between polyelectrolytes and oppositely charged colloids 230th ACS National Meeting, Polymer Division Preprints 2005
84. S. Ulrich, A. Laguecir, and S. Stoll Complex formation between a nanoparticle and a weak polyelectrolyte chain: Monte Carlo simulations J Nanopart Res 6 2004 595 603
85. K. Meyer-Hansen, H.A. Schols, G.A. De Ruiter, and A.G.J. Voragen Investigation of the non-esterified galacturonic acid distribution in pectin with endopolygalacturonase Carbohydr Res 318 1999 135 145
86. R.J. Darling, U. Kuchibhotla, and J.M. Beals Understanding the role of electrostatics in erythropoietin receptor/ligand system Gordon research conference on reversible associations in structural and molecular biology, Ventura, CA 2004 Nothing to do with polyelectrolytes, but raises doubts about the conventional view that long-range electrostatics in inter-macromolecular association under physiological conditions must be non-specific and non-selective.
87. G.S.V. Kuschert, F. Coulin, C.A. Power, A.E.I. Proudfoot, R.E. Hubbard, and A.J. Hoogewerf Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses Biochemistry 38 1999 12959 12968 This thorough investigation provided a greater understanding of chemokine-GAG (heparin and heparan sulfate) interaction on endothelial cell surfaces to stimulate the immune response. The chemokine RANTES (regulated on secretion normal T-cell expressed) bound immobilized heparin with the highest affinity and also was the most selective for various GAGs in competitive binding assays.
88. M. Rusnati, D. Coltrini, P. Oreste, G. Zoppetti, A. Albini, and D. Noonan Interaction of HIV-1 tat protein with heparin - role of the backbone structure, sulfation, and size J Biol Chem 272 1997 11313 11320 A study of GAG structure-function relationships. Biological assay and affinity chromatography indicate the role of heparin/heparan sulfate in inhibition of the HIV virus. The importance of heparin sulfation is illustrated by the reduced ability of selectively desulfated heparins to compete with unmodified heparins for Tat binding.
89. T. Sakamoto, E. Bonnin, and J.F. Thibault A new approach for studying interaction of the polygalacturonase-inhibiting proteins with pectins Biochim Biophys Acta-Gen Subj 1621 2003 280 284 One of few pectin cognate systems reported in the literature. The binding of polygalacturonase inhibiting proteins (PGIPs) to polygalacturonic acid (PGA) was found to increase when the degree of methylation or acetylation of PGA was decreased, indicative of electrostatic protein-PGA interaction.
90. A.V. Dobrynin, and M. Rubinstein Effect of short-range interactions on polyelectrolyte adsorption at charged surfaces J Phys Chem, B 107 2003 8260 8269
91. F. von Goeler, and M. Muthukumar Adsorption of polyelectrolytes onto curved surfaces J Chem Phys 100 1994 7796 7803
92. M. Muthukumar Pattern recognition by polyelectrolytes J Chem Phys 103 1995 4723 4731 A theory for binding between a negatively charged polyelectrolyte and a flat surface with a random distribution of positive charges. Binding was found to depend on charge densities and molecular weight of the polymer; charge density and size of the pattern, and the Debye length.
93. M. Ellis, C.Y. Kong, and M. Muthukumar Polyelectrolyte adsorption on heterogeneously charged surfaces J Chem Phys 112 2000 8723 8729 A Monte Carlo study of adsorption of a uniformly charged polyelectrolyte onto heterogeneously charged flat surfaces. Binding between similarly charged polyelectrolyte and surface was found to arise from spatial heterogeneity of surface charges.
94. R. de Vries, F. Weinbreck, and C.G. de Kruif Theory of polyelectrolyte adsorption on heterogeneously charges surfaces applied to soluble polyelectrolyte-protein complexes J Chem Phys 118 2003 4649 4659
95. F. Carlsson, P. Linse, and M. Malmsten Monte Carlo simulations of polyelectrolyte-protein complexation J Phys Chem, B 105 2001 9040 9049 A Monte Carlo study of complexation between a polyanion and a lysozyme. It was observed that the polyelectrolyte can bind to protein of the same charge sign only if short-range interactions are included. On the other hand, a maximum in the number of adsorbed polymer segments reaches a maximum when only electrostatic interactions are considered.
96. R. de Vries Monte Carlo simulations of flexible polyanions complexing with whey proteins at their isoelectric point J Chem Phys 120 2004 3475 3481
97. C. Schmitt, C. Sanchez, S. Desobry-Banon, and J. Hardy Structure and technofunctional properties of protein-polysaccharide complexes: a review Crit Rev Food Sci Nutr 38 1998 689 753
98. C.G. de Kruif, F. Weinbreck, and R. de Vries Complex coacervation of proteins and anionic polysaccharides Curr Opin Colloid Interface Sci 9 2004 340 349
99. Y. Wang, K. Kimura, Q. Huang, P.L. Dubin, and W. Jaeger Effects of salt on polyelectrolyte-micelle coacervation Macromolecules 32 1999 7128 7134
100. K. Kaibara, T. Okazaki, H.B. Bohidar, and P.L. Dubin pH-induced coacervation in complexes of bovine serum albumin and cationic polyelectrolytes Biomacromolecules 1 2000 100 107 Macromolecular assemblies of complexes between bovine serum albumin and poly(diallydimethylammonium chloride) (PDADMAC) were investigated at a pH range from 4 to 10 by turbidity, light scattering and phase contrast spectroscopy. It was found that temperature had no effect on neither on the pH of the onset of complexation (pHc) or on the point of initial coacervation (pHf). pHc was unaffected by an increase in protein: polyelectrolyte ratio, while pHf decreased.
101. F. Weinbreck, R.H. Tromp, and C.G. de Kruif Composition and structure of whey protein/gum arabic coacervates Biomacromolecules 5 2004 1437 1445
102. G. Decher Fuzzy nanoassemblies: toward layered polymeric multicomposites Science 277 1997 1232 1237 A milestone in polyelectrolyte multilayers that is heavily cited by protein-polyelectrolyte multilayer researchers. The layer-by-layer technique was introduced and possible applications including protein-polyelectrolyte multilayers were discussed.
103. L.E. Bromberg, and E.S. Ron Temperature-responsive gels and thermogelling polymer matrixes for protein and peptide delivery Adv Drug Deliv Rev 31 1998 197 221 A comprehensive review of temperature-responsive permanently cross-linked polyelectrolyte gels and their design for protein and drug delivery. Several studies of proteins loaded onto pH-sensitive polyelectrolyte hydrogels.
104. N.A. Peppas, and W. Leobandung Stimuli-sensitive hydrogels: ideal carriers for chronobiology and chronotherapy J Biomater Sci, Polym Ed 15 2004 125 144 A good review of hydrogels and factors affecting their swelling properties. An brief overview of stimuli-sensitive hydrogel systems used in protein/drug delivery is also given.
105. K. Ogawa, and E. Kokufuta Enzymatic formation of pH gradients within polyelectrolyte gels with immobilized urease Langmuir 18 2002 5661 5667
106. M.T. am Ende, D. Hariharan, and N.A. Peppas Factors influencing drug and protein transport and release from ionic hydrogels React Polym 25 1995 127 137
107. M. Leonard, M.R. De Boisseson, P. Hubert, F. Dalencon, and E. Dellacherie Hydrophobically modified alginate hydrogels as protein carriers with specific controlled release properties J Control Release 98 2004 395 405
108. Y. Ogawa, K. Ogawa, B. Wang, and E. Kokufuta A biochemo-mechanical system consisting of polyampholyte gels with coimmobilized glucose oxidase and urease Langmuir 17 2001 2670 2674
109. F. Caruso, H. Fiedler, and K. Haage Assembly of beta-glucosidase multilayers on spherical colloidal particles and their use as active catalysts Colloids Surf, A Physicochem Eng Asp 169 2000 287 293
110. T.D. Gibson, B.L.J. Pierce, J.N. Hulbert, and S. Gillespie Improvements in the stability characteristics of biosensors using protein-polyelectrolyte complexes Sens Actuators B, Chem 33 1996 13 18
111. N.A. Chaniotakis Enzyme stabilization strategies based on electrolytes and polyelectrolytes for biosensor applications Anal Bioanal Chem 378 2004 89 95
112. V.A. Izumrudov, I.Y. Galaev, and B. Mattiasson Polycomplexes-potential for bioseparation Bioseparation 7 1998 207 220
113. M.B. Dainiak, V.I. Muronetz, V.A. Izumrudov, I.Y. Galaev, and B. Mattiasson Production of Fab fragments of monoclonal antibodies using polyelectrolyte complexes Anal Biochem 277 2000 58 66
114. F. Weinbreck, M. Minor, and C.G. de Kruif Microencapsulation of oils using whey protein/gum arabic coacervates J Microencapsul 21 2004 667 679 Influence of pH, biopolymer concentration, and droplet size on microencapsulation of oils prepared using whey protein/gum arabic complex coacervates was studied by particle size and electrophoretic mobility measurements. The coacervate was most viscous and encapsulation was found to be optimized at the pH where the zeta potential of the complex was close to zero.
115. T.D. Gibson Protein stabilization using additives based on multiple electrostatic interactions Dev Biol Stand 87 1996 207 217 [new approaches to stabilisation of vaccines potency]
116. M. Mizusaki, Y. Morishima, and P.L. Dubin Interaction of pyrene-labeled hydrophobically modified polyelectrolytes with oppositely charged mixed micelles studied by fluorescence quenching J Phys Chem, B 102 1998 1908 1915
117. T. Sato, K.W. Mattison, P.L. Dubin, M. Kamachi, and Y. Morishima Effect of protein aggregation on the binding of lysozyme to pyrene-labeled polyanions Langmuir 14 1998 5430 5437