메뉴 건너뛰기




Volumn 3, Issue 8, 2005, Pages 738-742

Folate and methylenetetrahydrofolate reductase polymorphisms: New nutritional and genetic risk factors for pancreatic cancer?

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DIHYDROFOLATE REDUCTASE; FOLIC ACID;

EID: 23644460155     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1542-3565(05)00489-1     Document Type: Editorial
Times cited : (5)

References (41)
  • 1
    • 0002115597 scopus 로고
    • Folate chemistry and metabolism
    • L.B. Bailey Marcel Dekker New York
    • B. Shane Folate chemistry and metabolism L.B. Bailey Folate in health and disease 1995 Marcel Dekker New York 1 22
    • (1995) Folate in Health and Disease , pp. 1-22
    • Shane, B.1
  • 2
    • 0242610825 scopus 로고    scopus 로고
    • Role of folate in colon cancer development and progression
    • Y.I. Kim Role of folate in colon cancer development and progression J Nutr 133 2003 3731S 3739S
    • (2003) J Nutr , vol.133
    • Kim, Y.I.1
  • 3
    • 2942574352 scopus 로고    scopus 로고
    • Folate and DNA methylation: A mechanistic link between folate deficiency and colorectal cancer?
    • Y.I. Kim Folate and DNA methylation a mechanistic link between folate deficiency and colorectal cancer? Cancer Epidemiol Biomarkers Prev 13 2004 511 519
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 511-519
    • Kim, Y.I.1
  • 4
    • 0033007272 scopus 로고    scopus 로고
    • Folate and carcinogenesis: Evidence, mechanisms, and implications
    • Y.I. Kim Folate and carcinogenesis evidence, mechanisms, and implications J Nutr Biochem 10 1999 66 88
    • (1999) J Nutr Biochem , vol.10 , pp. 66-88
    • Kim, Y.I.1
  • 5
    • 0036328028 scopus 로고    scopus 로고
    • Folate status: Effects on pathways of colorectal carcinogenesis
    • S.W. Choi, J.B. Mason Folate status effects on pathways of colorectal carcinogenesis J Nutr 132 2002 2413S 2418S
    • (2002) J Nutr , vol.132
    • Choi, S.W.1    Mason, J.B.2
  • 6
    • 0035313224 scopus 로고    scopus 로고
    • Biological and clinical implications of the MTHFR C677T polymorphism
    • P.M. Ueland, S. Hustad, J. Schneede Biological and clinical implications of the MTHFR C677T polymorphism Trends Pharmacol Sci 22 2001 195 201
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 195-201
    • Ueland, P.M.1    Hustad, S.2    Schneede, J.3
  • 7
    • 0242610822 scopus 로고    scopus 로고
    • Folate, methyl-related nutrients, alcohol, and the MTHFR 677C - >T polymorphism affect cancer risk: Intake recommendations
    • L.B. Bailey Folate, methyl-related nutrients, alcohol, and the MTHFR 677C - >T polymorphism affect cancer risk intake recommendations J Nutr 133 2003 3748S 3753S
    • (2003) J Nutr , vol.133
    • Bailey, L.B.1
  • 8
    • 0028487161 scopus 로고
    • Human methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
    • P. Goyette, J.S. Sumner, R. Milos Human methylenetetrahydrofolate reductase isolation of cDNA, mapping and mutation identification Nat Genet 7 1994 195 200
    • (1994) Nat Genet , vol.7 , pp. 195-200
    • Goyette, P.1    Sumner, J.S.2    Milos, R.3
  • 9
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • P. Frosst, H.J. Blom, R. Milos A candidate genetic risk factor for vascular disease a common mutation in methylenetetrahydrofolate reductase Nat Genet 10 1995 111 113
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 10
    • 0028844492 scopus 로고
    • Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida
    • N.M. van der Put, R.P. Steegers-Theunissen, P. Frosst Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida Lancet 346 1995 1070 1071
    • (1995) Lancet , vol.346 , pp. 1070-1071
    • Van Der Put, N.M.1    Steegers-Theunissen, R.P.2    Frosst, P.3
  • 11
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • P.F. Jacques, A.G. Bostom, R.R. Williams Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations Circulation 93 1996 7 9
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3
  • 12
    • 0032573077 scopus 로고    scopus 로고
    • A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • P.J. Bagley, J. Selhub A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells Proc Natl Acad Sci U S A 95 1998 13217 13220
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.2
  • 13
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • J. Ma, M.J. Stampfer, E. Giovannucci Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer Cancer Res 57 1997 1098 1102
    • (1997) Cancer Res , vol.57 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3
  • 14
    • 0037117501 scopus 로고    scopus 로고
    • A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    • S. Friso, S.W. Choi, D. Girelli A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status Proc Natl Acad Sci U S A 99 2002 5606 5611
    • (2002) Proc Natl Acad Sci U S a , vol.99 , pp. 5606-5611
    • Friso, S.1    Choi, S.W.2    Girelli, D.3
  • 15
    • 0032895522 scopus 로고    scopus 로고
    • The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia
    • B.D. Guenther, C.A. Sheppard, P. Tran The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia Nat Struct Biol 6 1999 359 365
    • (1999) Nat Struct Biol , vol.6 , pp. 359-365
    • Guenther, B.D.1    Sheppard, C.A.2    Tran, P.3
  • 16
    • 0035909980 scopus 로고    scopus 로고
    • Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase
    • K. Yamada, Z. Chen, R. Rozen Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase Proc Natl Acad Sci U S A 98 2001 14853 14858
    • (2001) Proc Natl Acad Sci U S a , vol.98 , pp. 14853-14858
    • Yamada, K.1    Chen, Z.2    Rozen, R.3
  • 17
    • 0031971515 scopus 로고    scopus 로고
    • A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
    • N.M. van der Put, F. Gabreels, E.M. Stevens A second common mutation in the methylenetetrahydrofolate reductase gene an additional risk factor for neural-tube defects? Am J Hum Genet 62 1998 1044 1051
    • (1998) Am J Hum Genet , vol.62 , pp. 1044-1051
    • Van Der Put, N.M.1    Gabreels, F.2    Stevens, E.M.3
  • 18
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • I. Weisberg, P. Tran, B. Christensen A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity Mol Genet Metab 64 1998 169 172
    • (1998) Mol Genet Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3
  • 19
    • 0037377977 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: A HuGE minireview
    • K. Robien, C.M. Ulrich 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk a HuGE minireview Am J Epidemiol 157 2003 571 582
    • (2003) Am J Epidemiol , vol.157 , pp. 571-582
    • Robien, K.1    Ulrich, C.M.2
  • 20
    • 0032865186 scopus 로고    scopus 로고
    • A common mutation A1298C in human methylenetetrahydrofolate reductase gene: Association with plasma total homocysteine and folate concentrations
    • G. Friedman, N. Goldschmidt, Y. Friedlander A common mutation A1298C in human methylenetetrahydrofolate reductase gene association with plasma total homocysteine and folate concentrations J Nutr 129 1999 1656 1661
    • (1999) J Nutr , vol.129 , pp. 1656-1661
    • Friedman, G.1    Goldschmidt, N.2    Friedlander, Y.3
  • 21
    • 0034808335 scopus 로고    scopus 로고
    • A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk
    • K.J. Lievers, G.H. Boers, P. Verhoef A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk J Mol Med 79 2001 522 528
    • (2001) J Mol Med , vol.79 , pp. 522-528
    • Lievers, K.J.1    Boers, G.H.2    Verhoef, P.3
  • 22
    • 0036265638 scopus 로고    scopus 로고
    • Pharmacogenetics and folate metabolism: A promising direction
    • C.M. Ulrich, K. Robien, R. Sparks Pharmacogenetics and folate metabolism a promising direction Pharmacogenomics 3 2002 299 313
    • (2002) Pharmacogenomics , vol.3 , pp. 299-313
    • Ulrich, C.M.1    Robien, K.2    Sparks, R.3
  • 23
    • 0036016321 scopus 로고    scopus 로고
    • Linkage disequilibrium between the 677C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer
    • J. Chen, J. Ma, M.J. Stampfer Linkage disequilibrium between the 677C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer Pharmacogenetics 12 2002 339 342
    • (2002) Pharmacogenetics , vol.12 , pp. 339-342
    • Chen, J.1    Ma, J.2    Stampfer, M.J.3
  • 24
    • 0033527788 scopus 로고    scopus 로고
    • Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects (NTD)
    • K. Stegmann, A. Ziegler, E.T. Ngo Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects (NTD) Am J Med Genet 87 1999 23 29
    • (1999) Am J Med Genet , vol.87 , pp. 23-29
    • Stegmann, K.1    Ziegler, A.2    Ngo, E.T.3
  • 25
    • 0033794925 scopus 로고    scopus 로고
    • Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: An examination of C677T and A1298C mutations
    • P.A. Isotalo, G.A. Wells, J.G. Donnelly Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms an examination of C677T and A1298C mutations Am J Hum Genet 67 2000 986 990
    • (2000) Am J Hum Genet , vol.67 , pp. 986-990
    • Isotalo, P.A.1    Wells, G.A.2    Donnelly, J.G.3
  • 26
    • 0033869675 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: A paradigm of gene-nutrient interactions in carcinogenesis
    • Y.I. Kim Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk a paradigm of gene-nutrient interactions in carcinogenesis Nutr Rev 58 2000 205 209
    • (2000) Nutr Rev , vol.58 , pp. 205-209
    • Kim, Y.I.1
  • 27
    • 1442300286 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: A HuGE review
    • L. Sharp, J. Little Polymorphisms in genes involved in folate metabolism and colorectal neoplasia a HuGE review Am J Epidemiol 159 2004 423 443
    • (2004) Am J Epidemiol , vol.159 , pp. 423-443
    • Sharp, L.1    Little, J.2
  • 28
    • 0242317843 scopus 로고    scopus 로고
    • Nutritional links to plausible mechanisms underlying pancreatic cancer: A conference report
    • R.J. Hine, S. Srivastava, J.A. Milner Nutritional links to plausible mechanisms underlying pancreatic cancer a conference report Pancreas 27 2003 356 366
    • (2003) Pancreas , vol.27 , pp. 356-366
    • Hine, R.J.1    Srivastava, S.2    Milner, J.A.3
  • 30
    • 0036328451 scopus 로고    scopus 로고
    • Abnormal methyl metabolism in pancreatic toxicity and diabetes
    • D.S. Longnecker Abnormal methyl metabolism in pancreatic toxicity and diabetes J Nutr 132 2002 2373S 2376S
    • (2002) J Nutr , vol.132
    • Longnecker, D.S.1
  • 32
    • 0033577229 scopus 로고    scopus 로고
    • Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers
    • R.Z. Stolzenberg-Solomon, D. Albanes, F.J. Nieto Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers J Natl Cancer Inst 91 1999 535 541
    • (1999) J Natl Cancer Inst , vol.91 , pp. 535-541
    • Stolzenberg-Solomon, R.Z.1    Albanes, D.2    Nieto, F.J.3
  • 33
    • 0035313096 scopus 로고    scopus 로고
    • Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers
    • R.Z. Stolzenberg-Solomon, P. Pietinen, M.J. Barrett Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers Am J Epidemiol 153 2001 680 687
    • (2001) Am J Epidemiol , vol.153 , pp. 680-687
    • Stolzenberg-Solomon, R.Z.1    Pietinen, P.2    Barrett, M.J.3
  • 34
    • 0032545017 scopus 로고    scopus 로고
    • Dietary and nutritional factors and pancreatic cancer: A case-control study based on direct interviews
    • D.T. Silverman, C.A. Swanson, G. Gridley Dietary and nutritional factors and pancreatic cancer a case-control study based on direct interviews J Natl Cancer Inst 90 1998 1710 1719
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1710-1719
    • Silverman, D.T.1    Swanson, C.A.2    Gridley, G.3
  • 35
    • 3442898179 scopus 로고    scopus 로고
    • A prospective study of folate intake and the risk of pancreatic cancer in men and women
    • H.G. Skinner, D.S. Michaud, E.L. Giovannucci A prospective study of folate intake and the risk of pancreatic cancer in men and women Am J Epidemiol 160 2004 248 258
    • (2004) Am J Epidemiol , vol.160 , pp. 248-258
    • Skinner, H.G.1    Michaud, D.S.2    Giovannucci, E.L.3
  • 36
    • 23644452635 scopus 로고    scopus 로고
    • Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer
    • L. Wang, X. Miao, W. Tan Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer Clin Gastroenterol Hepatol 3 2005 743 751
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 743-751
    • Wang, L.1    Miao, X.2    Tan, W.3
  • 37
    • 23644457453 scopus 로고    scopus 로고
    • Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes
    • H. Matsubayashi, H.G. Skinner, C. Iacobuzio-Donahue Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes Clin Gastroenterol Hepatol 3 2005 752 760
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 752-760
    • Matsubayashi, H.1    Skinner, H.G.2    Iacobuzio-Donahue, C.3
  • 38
    • 1042292043 scopus 로고    scopus 로고
    • Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate
    • K.J. Sohn, R. Croxford, Z. Yates Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate J Natl Cancer Inst 96 2004 134 144
    • (2004) J Natl Cancer Inst , vol.96 , pp. 134-144
    • Sohn, K.J.1    Croxford, R.2    Yates, Z.3
  • 39
    • 16344368456 scopus 로고    scopus 로고
    • Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo
    • J. Stankova, J. Shang, R. Rozen Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo Clin Cancer Res 11 2005 2047 2052
    • (2005) Clin Cancer Res , vol.11 , pp. 2047-2052
    • Stankova, J.1    Shang, J.2    Rozen, R.3
  • 40
    • 0029848516 scopus 로고    scopus 로고
    • How safe are folic acid supplements?
    • N.R. Campbell How safe are folic acid supplements? Arch Intern Med 156 1996 1638 1644
    • (1996) Arch Intern Med , vol.156 , pp. 1638-1644
    • Campbell, N.R.1
  • 41
    • 16544370325 scopus 로고    scopus 로고
    • Will mandatory folic acid fortification prevent or promote cancer?
    • Y.I. Kim Will mandatory folic acid fortification prevent or promote cancer? Am J Clin Nutr 80 2004 1123 1128
    • (2004) Am J Clin Nutr , vol.80 , pp. 1123-1128
    • Kim, Y.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.