-
1
-
-
1642588228
-
Pancreatic cancer
-
D. Li, K. Xie, R. Wolff Pancreatic cancer Lancet 363 2004 1049 1057
-
(2004)
Lancet
, vol.363
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
-
4
-
-
0033970043
-
Folate and carcinogenesis: An integrated scheme
-
S.W. Choi, J.B. Mason Folate and carcinogenesis an integrated scheme J Nutr 130 2000 129 132
-
(2000)
J Nutr
, vol.130
, pp. 129-132
-
-
Choi, S.W.1
Mason, J.B.2
-
5
-
-
0032713838
-
Folic acid deficiency and cancer: Mechanisms of DNA instability
-
S.J. Duthie Folic acid deficiency and cancer mechanisms of DNA instability Br Med Bull 55 1999 578 592
-
(1999)
Br Med Bull
, vol.55
, pp. 578-592
-
-
Duthie, S.J.1
-
6
-
-
3442898179
-
A prospective study of folate intake and the risk of pancreatic cancer in man and women
-
H.G. Skinner, D.S. Michaud, E.L. Giovannucci A prospective study of folate intake and the risk of pancreatic cancer in man and women Am J Epidemiol 160 2004 248 258
-
(2004)
Am J Epidemiol
, vol.160
, pp. 248-258
-
-
Skinner, H.G.1
Michaud, D.S.2
Giovannucci, E.L.3
-
7
-
-
0035313096
-
Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers
-
R.Z. Stolzenberg-Solomon, P. Pietinen, M.J. Barrett Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers Am J Epidemiol 153 2001 680 687
-
(2001)
Am J Epidemiol
, vol.153
, pp. 680-687
-
-
Stolzenberg-Solomon, R.Z.1
Pietinen, P.2
Barrett, M.J.3
-
8
-
-
0033577229
-
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers
-
R.Z. Stolzenberg-Solomon, D. Albanes, F.J. Nieto Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers J Natl Cancer Inst 91 1999 535 541
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 535-541
-
-
Stolzenberg-Solomon, R.Z.1
Albanes, D.2
Nieto, F.J.3
-
9
-
-
0036328451
-
Abnormal methyl metabolism in pancreatic toxicity and diabetes
-
D.S. Longnecker Abnormal methyl metabolism in pancreatic toxicity and diabetes J Nutr 132 2002 2373S 2376S
-
(2002)
J Nutr
, vol.132
-
-
Longnecker, D.S.1
-
10
-
-
0027201593
-
Pancreatic one-carbon metabolism in early folate deficiency in rats
-
M. Balaghi, D.W. Horne, S.C. Woodward Pancreatic one-carbon metabolism in early folate deficiency in rats Am J Clin Nutr 58 1993 198 203
-
(1993)
Am J Clin Nutr
, vol.58
, pp. 198-203
-
-
Balaghi, M.1
Horne, D.W.2
Woodward, S.C.3
-
11
-
-
0026736179
-
Methyl group metabolism in the pancreas of folate-deficiency rats
-
M. Balaghi, C. Wagner Methyl group metabolism in the pancreas of folate-deficiency rats J Nutr 122 1992 1391 1396
-
(1992)
J Nutr
, vol.122
, pp. 1391-1396
-
-
Balaghi, M.1
Wagner, C.2
-
12
-
-
0034075153
-
Hypermethylation of multiple genes in pancreatic adenocarcinoma
-
T. Ueki, M. Toyota, T. Sohn Hypermethylation of multiple genes in pancreatic adenocarcinoma Cancer Res 60 2000 1835 1839
-
(2000)
Cancer Res
, vol.60
, pp. 1835-1839
-
-
Ueki, T.1
Toyota, M.2
Sohn, T.3
-
13
-
-
0035577825
-
Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma
-
T. Ueki, M. Toyota, H. Skinner Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma Cancer Res 61 2001 8540 8546
-
(2001)
Cancer Res
, vol.61
, pp. 8540-8546
-
-
Ueki, T.1
Toyota, M.2
Skinner, H.3
-
14
-
-
0042674172
-
Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma
-
N. Sato, A. Maitra, N. Fukushima Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma Cancer Res 63 2003 4158 4166
-
(2003)
Cancer Res
, vol.63
, pp. 4158-4166
-
-
Sato, N.1
Maitra, A.2
Fukushima, N.3
-
15
-
-
1542636969
-
Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling
-
N. Sato, N. Fukushima, H. Matsubayashi Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling Oncogene 23 2004 1531 1538
-
(2004)
Oncogene
, vol.23
, pp. 1531-1538
-
-
Sato, N.1
Fukushima, N.2
Matsubayashi, H.3
-
16
-
-
0033869675
-
Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: A paradigm of gene-nutrient interactions in carcinogenesis
-
Y.I. Kim Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk a paradigm of gene-nutrient interactions in carcinogenesis Nutr Rev 58 2000 205 209
-
(2000)
Nutr Rev
, vol.58
, pp. 205-209
-
-
Kim, Y.I.1
-
17
-
-
0142212221
-
Association between low dietary folate intake and suboptimal cellular DNA repair capacity
-
Q. Wei, H. Shen, L.-E. Wang Association between low dietary folate intake and suboptimal cellular DNA repair capacity Cancer Epidemiol Biomarkers Prev 12 2003 963 969
-
(2003)
Cancer Epidemiol Biomarkers Prev
, vol.12
, pp. 963-969
-
-
Wei, Q.1
Shen, H.2
Wang, L.-E.3
-
18
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
P. Frosst, H.J. Blom, R. Milos A candidate genetic risk factor for vascular disease a common mutation in methylenetetrahydrofolate reductase Nat Genet 10 1995 111 113
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
-
19
-
-
0031687887
-
A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
-
I. Weisberg, P. Tran, B. Christensen A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity Mol Genet Metab 64 1998 169 172
-
(1998)
Mol Genet Metab
, vol.64
, pp. 169-172
-
-
Weisberg, I.1
Tran, P.2
Christensen, B.3
-
20
-
-
0033846460
-
Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene
-
L.L. Stren, J.B. Mason, J. Selhub Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene Cancer Epidemiol Biomarkers Prev 9 2000 849 853
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 849-853
-
-
Stren, L.L.1
Mason, J.B.2
Selhub, J.3
-
21
-
-
2942700001
-
5,10-methylenetetrahydrofolate reductase (MTHFR) 677C→T and 1298A→C mutations are associated with DNA hypomethylation
-
R. Castro, I. Rivera, P. Ravasco 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C→T and 1298A→C mutations are associated with DNA hypomethylation J Med Genet 41 2004 454 458
-
(2004)
J Med Genet
, vol.41
, pp. 454-458
-
-
Castro, R.1
Rivera, I.2
Ravasco, P.3
-
22
-
-
0037117501
-
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
-
S. Friso, S.-W. Choi, D. Girelli A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status Proc Natl Acad Sci U S A 99 2002 5605 5611
-
(2002)
Proc Natl Acad Sci U S a
, vol.99
, pp. 5605-5611
-
-
Friso, S.1
Choi, S.-W.2
Girelli, D.3
-
23
-
-
4444363632
-
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo
-
S. Narayanan, J. McConnell, J. Little Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo Cancer Epidemiol Biomarkers Prev 13 2004 1436 1443
-
(2004)
Cancer Epidemiol Biomarkers Prev
, vol.13
, pp. 1436-1443
-
-
Narayanan, S.1
McConnell, J.2
Little, J.3
-
24
-
-
0035870245
-
Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population
-
C. Song, D. Xing, W. Tan Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population Cancer Res 61 2001 3272 3275
-
(2001)
Cancer Res
, vol.61
, pp. 3272-3275
-
-
Song, C.1
Xing, D.2
Tan, W.3
-
25
-
-
0036846722
-
Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population
-
X. Miao, D. Xing, W. Tan Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population Cancer Epidemiol Biomarkers Prev 11 2002 1454 1458
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 1454-1458
-
-
Miao, X.1
Xing, D.2
Tan, W.3
-
26
-
-
0035922101
-
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: A case-control study
-
H.B. Shen, Y.C. Xu, Y.X. Zheng Polymorphisms of 5,10- methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population a case-control study Int J Cancer 95 2001 332 336
-
(2001)
Int J Cancer
, vol.95
, pp. 332-336
-
-
Shen, H.B.1
Xu, Y.C.2
Zheng, Y.X.3
-
28
-
-
0029122937
-
Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5'-terminal regulatory region of the human gene for thymidylate synthase
-
N. Horie, H. Aiba, K. Oguro Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5'-terminal regulatory region of the human gene for thymidylate synthase Cell Struct Funct 20 1995 191 197
-
(1995)
Cell Struct Funct
, vol.20
, pp. 191-197
-
-
Horie, N.1
Aiba, H.2
Oguro, K.3
-
29
-
-
0035750549
-
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
-
S.T. Pullarkat, J. Stoehlmacher, V. Ghaderi Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy Pharmacogenomics J 1 2001 65 70
-
(2001)
Pharmacogenomics J
, vol.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
-
30
-
-
0037567591
-
A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity
-
M.V. Mandola, J. Stoehlmacher, S. Muller-Weeks A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity Cancer Res 63 2003 2898 2904
-
(2003)
Cancer Res
, vol.63
, pp. 2898-2904
-
-
Mandola, M.V.1
Stoehlmacher, J.2
Muller-Weeks, S.3
-
31
-
-
0141507954
-
Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene
-
K. Kawakami, G. Watanabe Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene Cancer Res 63 2003 6004 6007
-
(2003)
Cancer Res
, vol.63
, pp. 6004-6007
-
-
Kawakami, K.1
Watanabe, G.2
-
32
-
-
0142150084
-
Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer
-
J. Chen, D.J. Hunter, M.J. Stampfer Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer Cancer Epidemiol Biomarkers Prev 12 2003 958 962
-
(2003)
Cancer Epidemiol Biomarkers Prev
, vol.12
, pp. 958-962
-
-
Chen, J.1
Hunter, D.J.2
Stampfer, M.J.3
-
33
-
-
0037096858
-
Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas
-
C.M. Ulrich, J. Bigler, R. Bostick Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas Cancer Res 62 2002 3361 3364
-
(2002)
Cancer Res
, vol.62
, pp. 3361-3364
-
-
Ulrich, C.M.1
Bigler, J.2
Bostick, R.3
-
34
-
-
0037093272
-
Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia
-
C.F. Skibola, M.T. Smith, A. Hubbard Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia Blood 99 2002 3786 3791
-
(2002)
Blood
, vol.99
, pp. 3786-3791
-
-
Skibola, C.F.1
Smith, M.T.2
Hubbard, A.3
-
35
-
-
0037946769
-
Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma
-
A. Hishida, K. Matsuo, N. Hamajima Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma Haematologica 88 2003 159 166
-
(2003)
Haematologica
, vol.88
, pp. 159-166
-
-
Hishida, A.1
Matsuo, K.2
Hamajima, N.3
-
36
-
-
0036201835
-
Gene-environment interaction and etiology of cancer: What does it mean and how we measure it?
-
P. Brennan Gene-environment interaction and etiology of cancer what does it mean and how we measure it? Carcinogenesis 23 2002 381 387
-
(2002)
Carcinogenesis
, vol.23
, pp. 381-387
-
-
Brennan, P.1
-
37
-
-
0028783605
-
Alcohol and pancreatic cancer in blacks and whites in the United States
-
D.T. Silverman, L.M. Brown, R.N. Hoover Alcohol and pancreatic cancer in blacks and whites in the United States Cancer Res 55 1995 4899 4905
-
(1995)
Cancer Res
, vol.55
, pp. 4899-4905
-
-
Silverman, D.T.1
Brown, L.M.2
Hoover, R.N.3
-
38
-
-
0027939185
-
Local and systemic effects of cigarette smoking on folate and vitamin B-12
-
C.J. Piyathilake, M. Macaluso, R.J. Hine Local and systemic effects of cigarette smoking on folate and vitamin B-12 Am J Clin Nutr 60 1994 559 566
-
(1994)
Am J Clin Nutr
, vol.60
, pp. 559-566
-
-
Piyathilake, C.J.1
MacAluso, M.2
Hine, R.J.3
-
39
-
-
0034074390
-
Microbially produced acetaldehyde from ethanol may increase the risk of colon cancer via folate deficiency
-
N. Homann, J. Tillonen, M. Salaspuro Microbially produced acetaldehyde from ethanol may increase the risk of colon cancer via folate deficiency Int J Cancer 86 2000 169 173
-
(2000)
Int J Cancer
, vol.86
, pp. 169-173
-
-
Homann, N.1
Tillonen, J.2
Salaspuro, M.3
-
40
-
-
0029855024
-
Methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer
-
J. Chen, E. Giovannucci, K. Kelsey Methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer Cancer Res 56 1996 4862 4864
-
(1996)
Cancer Res
, vol.56
, pp. 4862-4864
-
-
Chen, J.1
Giovannucci, E.2
Kelsey, K.3
-
41
-
-
0030615085
-
Methylenetetrahydrofolate reductase polymorphism, dietary interaction, and risk of colorectal cancer
-
J. Ma, M.J. Stampfer, E. Giovannucci Methylenetetrahydrofolate reductase polymorphism, dietary interaction, and risk of colorectal cancer Cancer Res 57 1997 1098 1102
-
(1997)
Cancer Res
, vol.57
, pp. 1098-1102
-
-
Ma, J.1
Stampfer, M.J.2
Giovannucci, E.3
-
42
-
-
0022901191
-
The serum and red cell folate levels in pregnant women in Beijing
-
A. Zhang, X.-Q. Ge The serum and red cell folate levels in pregnant women in Beijing Chin Med J 99 1986 899 902
-
(1986)
Chin Med J
, vol.99
, pp. 899-902
-
-
Zhang, A.1
Ge, X.-Q.2
-
43
-
-
0033745130
-
Anemia and deficiencies of folate and vitamin B-6 are common and vary with season in Chinese women of childbearing age
-
A.G. Ronnenberg, M.B. Goldman, I.W. Aitken Anemia and deficiencies of folate and vitamin B-6 are common and vary with season in Chinese women of childbearing age J Nutr 130 2000 2703 2710
-
(2000)
J Nutr
, vol.130
, pp. 2703-2710
-
-
Ronnenberg, A.G.1
Goldman, M.B.2
Aitken, I.W.3
-
44
-
-
0242661097
-
Geographical, seasonal and gender differences in folate status among Chinese adults
-
L. Hao, J. Ma, M.J. Stampfer Geographical, seasonal and gender differences in folate status among Chinese adults J Nutr 133 2003 3630 3635
-
(2003)
J Nutr
, vol.133
, pp. 3630-3635
-
-
Hao, L.1
Ma, J.2
Stampfer, M.J.3
-
45
-
-
0033868044
-
Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia
-
C.J. Piyathilake, M. Macaluso, G. Johanning Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia Anticancer Res 20 2000 1751 1758
-
(2000)
Anticancer Res
, vol.20
, pp. 1751-1758
-
-
Piyathilake, C.J.1
MacAluso, M.2
Johanning, G.3
-
46
-
-
0031431662
-
Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility
-
M. Esteller, A. Garcia, J.M. Martinez-Palones Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility Carcinogenesis 18 1997 2307 2311
-
(1997)
Carcinogenesis
, vol.18
, pp. 2307-2311
-
-
Esteller, M.1
Garcia, A.2
Martinez-Palones, J.M.3
-
47
-
-
0033695123
-
Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women
-
R. Gershoni-Baruch, E. Dagan, D. Israeli Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women Eur J Cancer 36 2000 2313 2316
-
(2000)
Eur J Cancer
, vol.36
, pp. 2313-2316
-
-
Gershoni-Baruch, R.1
Dagan, E.2
Israeli, D.3
-
48
-
-
0033607241
-
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
-
C.F. Skibola, M.T. Smith, E. Kane Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults Proc Natl Acad Sci U S A 96 1999 2810 12815
-
(1999)
Proc Natl Acad Sci U S a
, vol.96
, pp. 2810-12815
-
-
Skibola, C.F.1
Smith, M.T.2
Kane, E.3
-
49
-
-
0035957379
-
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia
-
J.L. Wielems, R.N. Smith, G.M. Taylor Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia Proc Natl Acad Sci U S A 98 2001 4004 4009
-
(2001)
Proc Natl Acad Sci U S a
, vol.98
, pp. 4004-4009
-
-
Wielems, J.L.1
Smith, R.N.2
Taylor, G.M.3
-
50
-
-
2942608990
-
Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphomastic leukemia and non-Hodgkin's lymphoma in adults
-
D. Gemmati, A. Ongaro, G.L. Scapoli Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphomastic leukemia and non-Hodgkin's lymphoma in adults Cancer Epidemiol Biomarkers Prev 13 2004 787 794
-
(2004)
Cancer Epidemiol Biomarkers Prev
, vol.13
, pp. 787-794
-
-
Gemmati, D.1
Ongaro, A.2
Scapoli, G.L.3
-
51
-
-
9644294470
-
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and reduced risk of malignant lymphoma
-
K. Matsuo, N. Hamajima, R. Suzuki Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and reduced risk of malignant lymphoma Am J Hematol 77 2004 351 357
-
(2004)
Am J Hematol
, vol.77
, pp. 351-357
-
-
Matsuo, K.1
Hamajima, N.2
Suzuki, R.3
-
52
-
-
0038481232
-
Tobacco smoke exposure and decreased serum and red blood cell folate levels: Data from the third National Health and Nutrition Examination Survey
-
D.M. Mannino, J. Mulinare, E.S. Ford Tobacco smoke exposure and decreased serum and red blood cell folate levels data from the third National Health and Nutrition Examination Survey Nicotine Tob Res 5 2003 357 362
-
(2003)
Nicotine Tob Res
, vol.5
, pp. 357-362
-
-
Mannino, D.M.1
Mulinare, J.2
Ford, E.S.3
|