Effectiveness and limitations of β-blocker therapy in congenital long- QT syndrome

Circulation

Volumn 101, Issue 6, 2000, Pages 616-623

  Moss, Arthur J ^a,h   Zareba, Wojciech ^a   Hall, W Jackson ^a   Schwartz, Peter J ⁱ   Crampton, Richard S ^b   Benhorin, Jesaia ^e   Vincent, G Michael ^d   Locati, Emanuela H ^g   Priori, Silvia G ^c   Napolitano, Carlo ^c   Medina, Aharon ^e   Zhang, Li ^d   Robinson, Jennifer L ^a   Timothy, Katherine ^d   Towbin, Jeffrey A ^f   Andrews, Mark L ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^c IRCCS   (Italy)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^f BAYLOR COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF PERUGIA   (Italy)

^h UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

ⁱ NONE

Author keywords

Arrhythmia; Death, sudden; Heart arrest; Long QT syndrome; Syncope

Indexed keywords

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL; NADOLOL; PROPRANOLOL;

ADOLESCENT; ADULT; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CHILD; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HEART ARREST; HUMAN; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; PRIORITY JOURNAL; RISK FACTOR; SUDDEN DEATH; SURVIVAL; SYNCOPE; TREATMENT OUTCOME;

EID: 17044446589     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.6.616     Document Type: Article

References (9)

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3. Schwartz PJ, Locati E. Idiopathic long QT syndrome: pathogenic mechanisms and therapy. Eur Heart J. 1985;6(suppl D): 103-114.
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6. Moss AJ, McDonald J. Unilateral cervicothoracic sympathetic ganglionectomy for the treatment of long QT interval syndrome. N Engl J Med. 1970;285:903-904.
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8. Groh WJ, Silka MJ, Oliver RP, Halperin BD, McAnulty JH, Kron J. Use of implantable cardioverter-defibrillator in the congenital long QT syndrome. Am J Cardiol. 1996;78:703-706.
9. Cox DR. Regression models and life-tables. J R Slat Soc [B]. 1972;34: 187-220.