-
1
-
-
0027220197
-
Conformational coupling in DNA polymerase fidelity
-
Johnson,K.A. (1993) Conformational coupling in DNA polymerase fidelity. Annu. Rev. Biochem., 62, 685-713.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 685-713
-
-
Johnson, K.A.1
-
2
-
-
0037566670
-
Structural insights into the origins of DNA polymerase fidelity
-
Beard,W.A. and Wilson,S.H. (2003) Structural insights into the origins of DNA polymerase fidelity. Structure (Camb.), 11, 489-496.
-
(2003)
Structure (Camb.)
, vol.11
, pp. 489-496
-
-
Beard, W.A.1
Wilson, S.H.2
-
3
-
-
0037447258
-
High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds
-
Delaney,J.C., Henderson,P.T., Helquist,S.A., Morales,J.C., Essigmann,J.M. and Kool,E.T. (2003) High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds. Proc. Natl Acad. Sci. USA, 100, 4469-4473.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4469-4473
-
-
Delaney, J.C.1
Henderson, P.T.2
Helquist, S.A.3
Morales, J.C.4
Essigmann, J.M.5
Kool, E.T.6
-
4
-
-
0037162648
-
A highly effective nonpolar isostere of deoxyguanosine: Synthesis, structure, stacking, and base pairing
-
O'Neill,B.M., Ratto,J.E., Good,K.L., Tahmassebi,D.C., Helquist,S.A., Morales,J.C. and Kool,E.T. (2002) A highly effective nonpolar isostere of deoxyguanosine: Synthesis, structure, stacking, and base pairing. J. Org. Chem., 67, 5869-5875.
-
(2002)
J. Org. Chem.
, vol.67
, pp. 5869-5875
-
-
O'Neill, B.M.1
Ratto, J.E.2
Good, K.L.3
Tahmassebi, D.C.4
Helquist, S.A.5
Morales, J.C.6
Kool, E.T.7
-
5
-
-
0035852996
-
Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex
-
Dzantiev,L., Alekseyev,Y.O., Morales,J.C., Kool,E.T. and Romano,L.J. (2001) Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex. Biochemistry, 40, 3215-3221.
-
(2001)
Biochemistry
, vol.40
, pp. 3215-3221
-
-
Dzantiev, L.1
Alekseyev, Y.O.2
Morales, J.C.3
Kool, E.T.4
Romano, L.J.5
-
6
-
-
0034678016
-
Mimicking the structure and function of DNA: Insights into DNA stability and replication
-
Kool,E.T., Morales,J.C. and Guckian,K.M. (2000) Mimicking the structure and function of DNA: Insights into DNA stability and replication. Angew Chem. Int. Ed. Engl., 39, 990-1009.
-
(2000)
Angew Chem. Int. Ed. Engl.
, vol.39
, pp. 990-1009
-
-
Kool, E.T.1
Morales, J.C.2
Guckian, K.M.3
-
7
-
-
0034646194
-
Importance of terminal base pair hydrogen-bonding in 3′-end proofreading by the Klenow fragment of DNA polymerase I
-
Morales,J.C. and Kool,E.T. (2000) Importance of terminal base pair hydrogen-bonding in 3′-end proofreading by the Klenow fragment of DNA polymerase I. Biochemistry, 39, 2626-2632.
-
(2000)
Biochemistry
, vol.39
, pp. 2626-2632
-
-
Morales, J.C.1
Kool, E.T.2
-
8
-
-
0037183526
-
A reexamination of the nucleotide incorporation fidelity of DNA polymerases
-
Showalter,A.K. and Tsai,M.D. (2002) A reexamination of the nucleotide incorporation fidelity of DNA polymerases. Biochemistry, 41, 10571-10576.
-
(2002)
Biochemistry
, vol.41
, pp. 10571-10576
-
-
Showalter, A.K.1
Tsai, M.D.2
-
9
-
-
8544278025
-
DNA polymerase fidelity: Kinetics, structure, and checkpoints
-
Joyce,C.M. and Benkovic,S.J. (2004) DNA polymerase fidelity: Kinetics, structure, and checkpoints. Biochemistry, 43, 14317-14324.
-
(2004)
Biochemistry
, vol.43
, pp. 14317-14324
-
-
Joyce, C.M.1
Benkovic, S.J.2
-
10
-
-
0035997351
-
Active site tightness and substrate fit in DNA replication
-
Kool,E.T. (2002) Active site tightness and substrate fit in DNA replication. Aram. Rev. Biochem., 71, 191-219.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 191-219
-
-
Kool, E.T.1
-
11
-
-
0031792598
-
Efficient replication between non-hydrogen-bonded nucleoside shape analogs
-
Morales,J.C. and Kool,E.T. (1998) Efficient replication between non-hydrogen-bonded nucleoside shape analogs. Nature Struct. Biol., 5, 950-954.
-
(1998)
Nature Struct. Biol.
, vol.5
, pp. 950-954
-
-
Morales, J.C.1
Kool, E.T.2
-
12
-
-
0036408261
-
DNA minor groove hydration probed with 4′-alkylated thymidines
-
Detmer,I., Summerer,D. and Marx,A. (2002) DNA minor groove hydration probed with 4′-alkylated thymidines. Chem. Commun. (Camb.), 22, 2314-2315.
-
(2002)
Chem. Commun. (Camb.)
, vol.22
, pp. 2314-2315
-
-
Detmer, I.1
Summerer, D.2
Marx, A.3
-
13
-
-
0037174355
-
Implications of active site constraints on varied DNA polymerase selectivity
-
Strerath,M., Cramer,J., Restle,T. and Marx,A. (2002) Implications of active site constraints on varied DNA polymerase selectivity. J. Am. Chem. Soc., 124, 11230-11231.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 11230-11231
-
-
Strerath, M.1
Cramer, J.2
Restle, T.3
Marx, A.4
-
14
-
-
0036902098
-
Varied DNA polymerase-substrate interactions in the nucleotide binding pocket
-
Strerath,M., Summerer,D. and Marx,A. (2002) Varied DNA polymerase-substrate interactions in the nucleotide binding pocket. Chembiochem, 3, 578-580.
-
(2002)
Chembiochem
, vol.3
, pp. 578-580
-
-
Strerath, M.1
Summerer, D.2
Marx, A.3
-
15
-
-
0347367314
-
Exploring the effects of active site constraints on HIV-1 reverse transcriptase DNA polymerase fidelity
-
Cramer,J., Strerath,M., Marx,A. and Restle,T. (2002) Exploring the effects of active site constraints on HIV-1 reverse transcriptase DNA polymerase fidelity. J. Biol. Chem., 277, 43593-43598.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43593-43598
-
-
Cramer, J.1
Strerath, M.2
Marx, A.3
Restle, T.4
-
16
-
-
0028206048
-
Function and structure relationships in DNA polymerases
-
Joyce,C.M. and Steitz,T.A. (1994) Function and structure relationships in DNA polymerases. Annu. Rev. Biochem., 63, 777-822.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 777-822
-
-
Joyce, C.M.1
Steitz, T.A.2
-
17
-
-
0031587827
-
Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69
-
Wang,J., Sattar,A.K., Wang,C.C., Karam,J.D., Konigsberg,W.H. and Steitz,T.A. (1997) Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Cell, 89, 1087-1099.
-
(1997)
Cell
, vol.89
, pp. 1087-1099
-
-
Wang, J.1
Sattar, A.K.2
Wang, C.C.3
Karam, J.D.4
Konigsberg, W.H.5
Steitz, T.A.6
-
18
-
-
0032518374
-
A mechanism for all polymerases
-
Steitz,T.A. (1998) A mechanism for all polymerases. Nature, 391, 231-232.
-
(1998)
Nature
, vol.391
, pp. 231-232
-
-
Steitz, T.A.1
-
19
-
-
0032005866
-
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes
-
Brautigam,C.A. and Steitz,T.A. (1998) Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes. Curr Opin. Struct. Biol., 8, 54-63.
-
(1998)
Curr. Opin. Struct. Biol.
, vol.8
, pp. 54-63
-
-
Brautigam, C.A.1
Steitz, T.A.2
-
20
-
-
0033581011
-
DNA polymerases: Structural diversity and common mechanisms
-
Steitz,T.A. (1999) DNA polymerases: Structural diversity and common mechanisms. J. Biol. Chem., 274, 17395-17398.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17395-17398
-
-
Steitz, T.A.1
-
21
-
-
0035826622
-
Insight into the catalytic mechanism of DNA polymerase beta: Structures of intermediate complexes
-
Arndt,J.W., Gong,W., Zhong,X., Showalter,A.K., Liu,J., Dunlap,C.A., Lin,Z., Paxson,C., Tsai,M.D. and Chan,M.K. (2001) Insight into the catalytic mechanism of DNA polymerase beta: Structures of intermediate complexes. Biochemistry, 40, 5368-5375.
-
(2001)
Biochemistry
, vol.40
, pp. 5368-5375
-
-
Arndt, J.W.1
Gong, W.2
Zhong, X.3
Showalter, A.K.4
Liu, J.5
Dunlap, C.A.6
Lin, Z.7
Paxson, C.8
Tsai, M.D.9
Chan, M.K.10
-
22
-
-
1542375156
-
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology
-
Garcia-Diaz,M., Bebenek,K., Krahn,J.M., Blanco,L., Kunkel,T.A. and Pedersen,L.C. (2004) A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol. Cell., 13, 561-572.
-
(2004)
Mol. Cell.
, vol.13
, pp. 561-572
-
-
Garcia-Diaz, M.1
Bebenek, K.2
Krahn, J.M.3
Blanco, L.4
Kunkel, T.A.5
Pedersen, L.C.6
-
23
-
-
0033622011
-
Terminal deoxynucleotidyl transferase. Catalysis of DNA (oligodeoxynucleotide) phosphorylation
-
Krayevsky,A.A., Victorova,L.S., Arzumanov,A.A. and Jasko,M.V. (2000) Terminal deoxynucleotidyl transferase. Catalysis of DNA (oligodeoxynucleotide) phosphorylation. Pharmacol. Ther., 85, 165-173.
-
(2000)
Pharmacol. Ther.
, vol.85
, pp. 165-173
-
-
Krayevsky, A.A.1
Victorova, L.S.2
Arzumanov, A.A.3
Jasko, M.V.4
-
24
-
-
0034159891
-
Terminal deoxynucleotidyl transferase catalyzes the reaction of DNA phosphorylation
-
Arzumanov,A.A., Victorova,L.S., Jasko,M.V., Yesipov,D.S. and Krayevsky,A.A. (2000) Terminal deoxynucleotidyl transferase catalyzes the reaction of DNA phosphorylation. Nucleic Acids Res., 28, 1276-1281.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1276-1281
-
-
Arzumanov, A.A.1
Victorova, L.S.2
Jasko, M.V.3
Yesipov, D.S.4
Krayevsky, A.A.5
-
25
-
-
0035997349
-
Eukaryotic DNA polymerases
-
Hubscher,U., Maga,G. and Spadari,S. (2002) Eukaryotic DNA polymerases. Annu. Rev. Biochem., 71, 133-163.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 133-163
-
-
Hubscher, U.1
Maga, G.2
Spadari, S.3
-
26
-
-
12544254854
-
DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A
-
Maga,G., Ramadan,K., Locatelli,G.A., Shevelev,I., Spadari,S. and Hubscher,U. (2005) DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A. J. Biol. Chem., 280, 1971-1981.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1971-1981
-
-
Maga, G.1
Ramadan, K.2
Locatelli, G.A.3
Shevelev, I.4
Spadari, S.5
Hubscher, U.6
-
27
-
-
0037732696
-
Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: A kinetic and thermodynamic study
-
Blanca,G., Shevelev,I., Ramadan,K., Villani,G., Spadari,S., Hubscher,U. and Maga,G. (2003) Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: A kinetic and thermodynamic study. Biochemistry, 42, 7467-7476.
-
(2003)
Biochemistry
, vol.42
, pp. 7467-7476
-
-
Blanca, G.1
Shevelev, I.2
Ramadan, K.3
Villani, G.4
Spadari, S.5
Hubscher, U.6
Maga, G.7
-
28
-
-
0344668821
-
Mutagenesis of human DNA polymerase lambda: Essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities
-
Shevelev,I., Blanca,G., Villani,G., Ramadan,K., Spadari,S., Hubscher,U. and Maga,G. (2003) Mutagenesis of human DNA polymerase lambda: Essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities. Nucleic Acids Res., 31, 6916-6925.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6916-6925
-
-
Shevelev, I.1
Blanca, G.2
Villani, G.3
Ramadan, K.4
Spadari, S.5
Hubscher, U.6
Maga, G.7
-
29
-
-
9444261887
-
The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1
-
Maga,G., Blanca,G., Shevelev,I., Frouin,I., Ramadan,K., Spadari,S., Villani,G. and Hubscher,U. (2004) The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1. FASEB J, 18, 1743-1745.
-
(2004)
FASEB J.
, vol.18
, pp. 1743-1745
-
-
Maga, G.1
Blanca, G.2
Shevelev, I.3
Frouin, I.4
Ramadan, K.5
Spadari, S.6
Villani, G.7
Hubscher, U.8
-
30
-
-
0025781295
-
Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus
-
Weiser,T., Gassmann,M., Thommes,P., Ferrari,E., Hafkemeyer,P. and Hubscher,U. (1991) Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. J. Biol. Chem., 266, 10420-10428.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 10420-10428
-
-
Weiser, T.1
Gassmann, M.2
Thommes, P.3
Ferrari, E.4
Hafkemeyer, P.5
Hubscher, U.6
-
31
-
-
0031578901
-
Resistance to nevirapine of HIV-1 reverse transcriptase mutants: Loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions
-
Maga,G., Amacker,M., Ruel,N., Hubscher,U. and Spadari,S. (1997) Resistance to nevirapine of HIV-1 reverse transcriptase mutants: Loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. J. Mol. Biol., 274, 738-747.
-
(1997)
J. Mol. Biol.
, vol.274
, pp. 738-747
-
-
Maga, G.1
Amacker, M.2
Ruel, N.3
Hubscher, U.4
Spadari, S.5
-
32
-
-
0040302434
-
The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product
-
Hubscher,U. and Kornberg,A. (1979) The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product. Proc. Natl Acad. Sci USA, 76, 6284-6288.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 6284-6288
-
-
Hubscher, U.1
Kornberg, A.2
-
33
-
-
2242420935
-
Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis
-
Maga,G., Villani,G., Ramadan,K., Shevelev,I., Le Gac,N.T., Blanco,L., Blanca,G., Spadari,S. and Hubscher,U. (2002) Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis. J. Biol. Chem., 277, 48434-48440.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48434-48440
-
-
Maga, G.1
Villani, G.2
Ramadan, K.3
Shevelev, I.4
Le Gac, N.T.5
Blanco, L.6
Blanca, G.7
Spadari, S.8
Hubscher, U.9
-
34
-
-
0029843045
-
A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
-
Pelletier,H., Sawaya,M.R., Wolfle,W., Wilson,S.H. and Kraut,J. (1996) A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta. Biochemistry, 35, 12762-12777.
-
(1996)
Biochemistry
, vol.35
, pp. 12762-12777
-
-
Pelletier, H.1
Sawaya, M.R.2
Wolfle, W.3
Wilson, S.H.4
Kraut, J.5
-
35
-
-
0029817866
-
Crystal structures of human DNA polymerase beta complexed with DNA: Implications for catalytic mechanism, processivity, and fidelity
-
Pelletier,H., Sawaya,M.R., Wolfle,W., Wilson,S.H. and Kraut,J. (1996) Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. Biochemistry, 35, 12742-12761.
-
(1996)
Biochemistry
, vol.35
, pp. 12742-12761
-
-
Pelletier, H.1
Sawaya, M.R.2
Wolfle, W.3
Wilson, S.H.4
Kraut, J.5
-
36
-
-
0028136070
-
Crystal structure of rat DNA polymerase beta: Evidence for a common polymerase mechanism
-
Sawaya,M.R., Pelletier,H., Kumar,A., Wilson,S.H. and Kraut,J. (1994) Crystal structure of rat DNA polymerase beta: Evidence for a common polymerase mechanism. Science, 264, 1930-1935.
-
(1994)
Science
, vol.264
, pp. 1930-1935
-
-
Sawaya, M.R.1
Pelletier, H.2
Kumar, A.3
Wilson, S.H.4
Kraut, J.5
-
37
-
-
11444264188
-
A closed conformation for the Polymerase lambda catalytic cycle
-
Garcia-Diaz,M., Bebenek,K., Krahn,J.M., Kunkel,T.A. and Pedersen,L.C. (2005) A closed conformation for the Polymerase lambda catalytic cycle. Nature Struct. Mol. Biol., 12, 97-98.
-
(2005)
Nature Struct. Mol. Biol.
, vol.12
, pp. 97-98
-
-
Garcia-Diaz, M.1
Bebenek, K.2
Krahn, J.M.3
Kunkel, T.A.4
Pedersen, L.C.5
-
38
-
-
4444337946
-
Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation
-
Blanca,G., Villani,G., Shevelev,I., Ramadan,K., Spadari,S., Hubscher,U. and Maga,G. (2004) Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation. Biochemistry, 43, 11605-11615.
-
(2004)
Biochemistry
, vol.43
, pp. 11605-11615
-
-
Blanca, G.1
Villani, G.2
Shevelev, I.3
Ramadan, K.4
Spadari, S.5
Hubscher, U.6
Maga, G.7
-
39
-
-
0036469941
-
Crystal structures of a template-independent DNA polymerase: Murine terminal deoxynucleotidyltransferase
-
Delarue,M., Boule,J.B., Lescar,J., Expert-Bezancon,N., Jourdan,N., Sukumar,N., Rougeon,F. and Papanicolaou,C. (2002) Crystal structures of a template-independent DNA polymerase: Murine terminal deoxynucleotidyltransferase. EMBO J., 21, 427-439.
-
(2002)
EMBO J.
, vol.21
, pp. 427-439
-
-
Delarue, M.1
Boule, J.B.2
Lescar, J.3
Expert-Bezancon, N.4
Jourdan, N.5
Sukumar, N.6
Rougeon, F.7
Papanicolaou, C.8
-
40
-
-
23944510372
-
New substrates of terminal deoxynucleotidyl transferase: Synthesis and biological evaluation
-
Khandazhinskaya,A.L., Jasko,M.V., Shirokova,E.A. and Kukhanova,M.K. (2002) New substrates of terminal deoxynucleotidyl transferase: synthesis and biological evaluation. Collection Symposium Series, 5, 344-347.
-
(2002)
Collection Symposium Series
, vol.5
, pp. 344-347
-
-
Khandazhinskaya, A.L.1
Jasko, M.V.2
Shirokova, E.A.3
Kukhanova, M.K.4
-
41
-
-
23944482104
-
New non-nucleoside substrates of terminal deoxynucleotidyl transferase: Synthesis and evaluation of dependence of substrate properties from the structure
-
in press
-
Khandazhinskaya,A.L., Kukhanova,M.K. and Jasko,M.V. (2005) New non-nucleoside substrates of terminal deoxynucleotidyl transferase: synthesis and evaluation of dependence of substrate properties from the structure. Bioorg. Khim., 31, in press.
-
(2005)
Bioorg. Khim.
, vol.31
-
-
Khandazhinskaya, A.L.1
Kukhanova, M.K.2
Jasko, M.V.3
|