A-ring-substituted estrogen-3-O-sulfamates: Potent multitargeted anticancer agents

Journal of Medicinal Chemistry

Volumn 48, Issue 16, 2005, Pages 5243-5256

  Leese, Mathew P ^a   Hejaz, Hatem A M ^a   Mahon, Mary F ^b   Newman, Simon P ^c   Purohit, Atul ^c   Reed, Michael J ^a   Potter, Barry V L ^a  

^a UNIVERSITY OF BATH   (United Kingdom)

^b University of Bath Claverton Down   (United Kingdom)

^c ST MARY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYLESTRADIOL 3 O SULFAMATE; 2 ETHYLESTRONE 3 O SULFAMATE; 2 METHOXYESTRADIOL; 2 METHOXYESTRADIOL 3 O SULFAMATE; 2 METHOXYESTRONE 3 O SULFAMATE; 2 METHYLSULFANYLESTRADIOL 3 O SULFAMATE; 2 METHYLSULFANYLESTRONE 3 O SULFAMATE; ESTRADIOL DERIVATIVE; ESTROGEN DERIVATIVE; STERYL SULFATASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; TUMOR XENOGRAFT;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; ESTRADIOL; ESTRONE; FEMALE; HUMANS; MICE; MOLECULAR STRUCTURE; STERYL-SULFATASE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS; TRANSPLANTATION, HETEROLOGOUS;

EID: 23444441492     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050066a     Document Type: Article

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