The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity

Journal of Steroid Biochemistry and Molecular Biology

Volumn 64, Issue 5-6, 1998, Pages 269-275

  Purohit, A ^a   Vernon, K A ^a   Wagenaar Hummelinck, A E ^a   Woo, L W L ^b   Hejaz, H A M ^b   Potter, B V L ^b   Reed, M J ^a  

^a ST MARY S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BATH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; ESTROGEN; STERYL SULFATASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST TUMOR; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DEVELOPMENT; DRUG EFFECT; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; MICROSOME; UTERUS GROWTH;

ANIMALS; ARYLSULFATASES; BREAST NEOPLASMS; ENZYME INHIBITORS; ESTRONE; FEMALE; MICROSOMES; MOLECULAR STRUCTURE; ORGAN SIZE; OVARIECTOMY; PLACENTA; RATS; RATS, INBRED STRAINS; STERYL-SULFATASE; UTERUS;

EID: 0031947952     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(97)00196-9     Document Type: Article

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