Directed evolution of protein enzymes using nonhomologous random recombination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 18, 2004, Pages 7011-7016

  Bittker, Joshua A ^a   Le, Brian V ^a   Liu, Jane M ^a   Liu, David R ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; CHORISMATE MUTASE; DNA; FUMARATE HYDRATASE;

ALPHA HELIX; ARTICLE; DIRECTED MOLECULAR EVOLUTION; GENE DELETION; GENE INSERTION; GENE REARRANGEMENT; GENETIC RECOMBINATION; METHANOCOCCUS JANNASCHII; NONHOMOLOGOUS RANDOM RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MOTIF; SEQUENCE ANALYSIS;

CHORISMATE MUTASE; DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS;

INSERTION SEQUENCES; METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS;

EID: 2342642643     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0402202101     Document Type: Article

References (28)

1. Santoro, S. W. & Schultz, P. G. (2002) Proc. Natl. Acad. Sci. USA 99, 4185-4190.
2. Wang, L., Brock, A., Herberich, B. & Schultz, P. G. (2001) Science 292, 498-500.
3. Crameri, A., Whitehorn, E. A., Tate, E. & Stemmer, W. P. (1996) Nat. Biotechnol. 14, 315-319.
4. Stemmer, W. P. (1994) Nature 370, 389-391.
5. Lim, W. A. & Sauer, R. T. (1989) Nature 339, 31-36.
6. Taylor, S. V., Walter, K. U., Kast, P. & Hilvert, D. (2001) Proc. Natl. Acad. Sci. USA 98, 10596-10601.
7. MacBeath, G., Kast, P. & Hilvert, D. (1998) Science 279, 1958-1961.
8. Kast, P., Grisostomi, C., Chen, I. A., Li, S., Krengel, U., Xue, Y. & Hilvert, D. (2000) J. Biol. Chem. 275, 36832-36838.
9. Bogarad, L. D. & Deem, M. W. (1999) Proc. Natl. Acad. Sci. USA 96, 2591-2595.
10. Babbitt, P. C. & Gerlt, J. A. (1997) J. Biol. Chem. 272, 30591-30594.
11. Hiraga, K. & Arnold, F. H. (2003) J. Mol. Biol. 330, 287-296.
12. O'Maille, P. E., Bakhtina, M. & Tsai, M. D. (2002) J. Mol. Biol. 321, 677-691.
13. Tsuji, T., Onimaru, M. & Yanagawa, H. (2001) Nucleic Acids Res. 29, e97.
14. Sieber, V., Martinez, C. A. & Arnold, F. H. (2001) Nat. Biotechnol. 19, 456-460.
15. Ostermeier, M., Shim, J. H. & Benkovic, S. J. (1999) Nat. Biotechnol. 17, 1205-1209.
16. Lutz, S., Ostermeier, M., Moore, G. L., Maranas, C. D. & Benkovic, S. J. (2001) Proc. Natl. Acad. Sci. USA 98, 11248-11253.
17. Kawarasaki, Y., Griswold, K. E., Stevenson, J. D., Selzer, T., Benkovic, S. J., Iverson, B. L. & Georgiou, G. (2003) Nucleic Acids Res. 31, e126.
18. Bittker, J. A., Le, B. V. & Liu, D. R. (2002) Nat. Biotechnol. 20, 1024-1029.
19. Kast, P., AsifUllah, M. & Hilvert, D. (1996) Tetrahedron Lett. 2691-2694.
20. Kast, P., Asif-Ullah, M., Jiang, N. & Hilvert, D. (1996) Proc. Natl. Acad. Sci. USA 93, 5043-5048.
21. Gamper, M., Hilvert, D. & Kast, P. (2000) Biochemistry 39, 14087-14094.
22. Schuler, G. D., Altschul, S. F. & Lipman, D. J. (1991) Proteins 9, 180-190.
23. Cload, S. T., Liu, D. R., Pastor, R. M. & Schultz, P. G. (1996) J. Am. Chem. Soc. 118, 1787-1788.
24. Weaver, T. & Banaszak, L. (1996) Biochemistry 35, 13955-13965.
25. MacBeath, G., Kast, P. & Hilvert, D. (1998) Biochemistry 37, 10062-10073.
26. Lee, A. Y., Karplus, P. A., Ganem, B. & Clardy, J. (1995) J. Am. Chem. Soc. 117, 3627-3628.
27. MacBeath, G., Kast, P. & Hilvert, D. (1998) Protein Sci. 7, 325-335.
28. Chen, S., Vincent, S., Wilson, D. B. & Ganem, B. (2003) Eur. J. Biochem. 270, 757-763.