Phenotypic screening for pharmaceuticals using tissue constructs

Current Pharmaceutical Biotechnology

Volumn 5, Issue 2, 2004, Pages 181-189

  Wakatsuki, T ^a   Fee, J A ^a   Elson, E L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

High throughput screening; Phenotypic screening; Tissue constructs; Tissue mechanics

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; BREFELDIN A; COLCHICINE; CYCLOPEPTIDE; CYTOCHALASIN D; DARODIPINE; DRUG RECEPTOR; DYSTROPHIN; EXOL; GREEN FLUORESCENT PROTEIN; HYDROLASE INHIBITOR; ISOPRENALINE; KINESIN; LATRUNCULIN B; MONASTROL; NOCODAZOLE; PACLITAXEL; PROTEIN INHIBITOR; PROTEIN KINASE INHIBITOR; RHO KINASE; UNCLASSIFIED DRUG; VASOPRESSIN; VINBLASTINE; Y 27662;

ACTION POTENTIAL; BLOOD PRESSURE REGULATION; CELL ACTIVITY; CELL FUNCTION; CELL SPECIFICITY; CELL STRUCTURE; CELL TYPE; CONNECTIVE TISSUE; DRUG ACTIVITY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RESPONSE; DRUG SCREENING; DUCHENNE MUSCULAR DYSTROPHY; EXTRACELLULAR MATRIX; FIBROBLAST; FLUORESCENCE ANALYSIS; FLUORESCENCE CORRELATION SPECTROSCOPY; HEART MUSCLE; HEART MUSCLE CELL; MOLECULAR MODEL; MUSCLE CONTRACTION; NONHUMAN; PHENOTYPE; REVIEW; SAMPLING; SKELETAL MUSCLE; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; TIME; TISSUE ENGINEERING; TISSUE STRUCTURE; VASCULAR SMOOTH MUSCLE; VOLUMETRY; WOUND HEALING;

ANIMALS; CELL LINE; CONNECTIVE TISSUE CELLS; DRUG EVALUATION, PRECLINICAL; DRUGS, INVESTIGATIONAL; EXTRACELLULAR MATRIX; GENETIC MARKERS; HUMANS; MUSCLE, SKELETAL; MYOCYTES, CARDIAC; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; TISSUE ENGINEERING;

EID: 2342527098     PISSN: 13892010     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389201043376940     Document Type: Review

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