Taxol, vincristine or nocodazole induces lethality in G1-checkpoint-defective human astrocytoma U373MG cells by triggering hyperploid progression

Carcinogenesis

Volumn 20, Issue 7, 1999, Pages 1161-1168

  Hong, Frank D ^a   Chen, Jun ^b   Donovan, Scott ^c   Schneider, Nancy ^c   Nisen, Perry D ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ABBOTT LABORATORIES   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; HYDROXYUREA; NOCODAZOLE; PACLITAXEL; PROTEIN P27; PROTEIN P53; RETINOBLASTOMA PROTEIN; VINCRISTINE;

ARTICLE; ASTROCYTOMA; CELL CYCLE G1 PHASE; CELL DEATH; CELL DIVISION; CHROMOSOME NUMBER; CONTROLLED STUDY; CYTOLYSIS; DRUG MECHANISM; GENE FUNCTION; HUMAN; HUMAN CELL; POLYPLOIDY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ASTROCYTOMA; CELL CYCLE; CELL CYCLE PROTEINS; CELL DEATH; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; HYDROXYUREA; KARYOTYPING; MICROTUBULE-ASSOCIATED PROTEINS; NOCODAZOLE; PACLITAXEL; PHOSPHORYLATION; POLYPLOIDY; RETINOBLASTOMA PROTEIN; THYMIDINE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; VINCRISTINE;

EID: 0032804225     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.7.1161     Document Type: Article

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