Guided docking approaches to structure-based design and screening

Current Topics in Medicinal Chemistry

Volumn 4, Issue 7, 2004, Pages 687-700

  Fradera, Xavier ^a   Mestres, Jordi ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE II; CYCLOOXYGENASE 2; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; DOCKING PROTEIN; ENDOTHIAPEPSIN; ESTROGEN; FK 506 BINDING PROTEIN; GELATINASE A; LIGAND; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROGESTERONE; PROTEIN TYROSINE KINASE INHIBITOR; PROTEINASE INHIBITOR; SERINE PROTEINASE; SIALIDASE; THERMOLYSIN; THROMBIN; THROMBIN INHIBITOR; TRYPSIN INHIBITOR; URACIL DNA GLYCOSYLTRANSFERASE; PROTEIN;

ALGORITHM; AUTOMATION; BINDING AFFINITY; BINDING SITE; COMBINATORIAL LIBRARY; DRUG DESIGN; DRUG SCREENING; ENTROPY; LIGAND BINDING; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; REVIEW; SOLVATION; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER AIDED DESIGN; STRUCTURE ACTIVITY RELATION;

BINDING SITES; COMPUTER-AIDED DESIGN; DRUG DESIGN; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2342514226     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026043451104     Document Type: Review

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