DoMCoSAR: A novel approach for establishing the docking mode that is consistent with the structure - Activity relationship. Application to HIV-1 protease inhibitors and VEGF receptor tyrosine kinase inhibitors

Journal of Medicinal Chemistry

Volumn 43, Issue 16, 2000, Pages 3020-3032

  Vieth, M ^a   Cummins, D J ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; INDOLE DERIVATIVE; L 689502; OXOINDOLE; PROTEIN TYROSINE KINASE INHIBITOR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

ARTICLE; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND BINDING; MODEL; NONHUMAN; PROTEINASE INHIBITION; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION;

CRYSTALLOGRAPHY, X-RAY; HIV PROTEASE INHIBITORS; HIV-1; INDOLES; LIGANDS; MODELS, MOLECULAR; MORPHOLINES; PEPTIDES; PROTEIN BINDING; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034632804     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990609e     Document Type: Article

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