Carcinogen-induced colon tumors in mice are chromosomally stable and are characterized by low-level microsatellite instability

Oncogene

Volumn 23, Issue 21, 2004, Pages 3813-3821

  Guda, Kishore ^a   Upender, Madhvi B ^b   Belinsky, Glenn ^a   Flynn, Christopher ^a   Nakanishi, Masako ^a   Marino, Jillian N ^a   Ried, Thomas ^b   Rosenberg, Daniel W ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Azoxymethane; Chromosomal instability; Colon tumorigenesis; Mice; Microsatellite instability; Spectral karyotyping

Indexed keywords

APC PROTEIN; AZOXYMETHANE; BETA CATENIN; CARCINOGEN; K RAS PROTEIN; SODIUM CHLORIDE; WNT PROTEIN; CATNB PROTEIN, MOUSE; CYTOSKELETON PROTEIN; MICROSATELLITE DNA; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CARCINOMA IN SITU; CELL CULTURE; CHROMOSOME 2; CHROMOSOME ABERRATION; CHROMOSOME LOSS; COLON CANCER; COLON TUMOR; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; GENE FREQUENCY; GENE MUTATION; MALE; MICROSATELLITE INSTABILITY; MOLECULAR GENETICS; MOUSE; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPECTRAL KARYOTYPING; STATISTICAL SIGNIFICANCE; TUMOR CELL LINE; Y CHROMOSOME; ANEUPLOIDY; ANIMAL; CHEMICALLY INDUCED DISORDER; GENETICS; GENOMIC INSTABILITY; PATHOLOGY;

ANIMALIA; MURINAE;

ANEUPLOIDY; ANIMALS; AZOXYMETHANE; BETA CATENIN; COLONIC NEOPLASMS; CYTOSKELETAL PROTEINS; GENOMIC INSTABILITY; MALE; MICE; MICROSATELLITE REPEATS; TRANS-ACTIVATORS;

EID: 2342505129     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207489     Document Type: Article

References (48)

1. Brink M, de Goeij AF, Weijenberg MP, Roemen GM, Lentjes MH, Pachen MM, Smits KM, de Bruine AP, Goldbohm RA and van den Brandt PA. (2003). Carcinogenesis, 24, 703-710.
2. Calvert PM and Frucht H. (2002). Ann. Intern. Med., 137, 603-612.
3. Chan TL, Curtis LC, Leung SY, Farrington SM, Ho JW, Chan AS, Lam PW, Tse CW, Dunlop MG, Wyllie AH and Yuen ST. (2001). Oncogene, 20, 4871-4876.
4. Corpet DE and Pierre F. (2003). Cancer Epidemiol. Biomarkers Prev., 12, 391-400.
5. De Filippo C, Caderni G, Bazzicalupo M, Briani C, Giannini A, Fazi M and Dolara P. (1998). Br. J. Cancer, 77, 2148-2151.
6. Dong M, Guda K, Nambiar PR, Rezaie A, Belinsky GS, Lambeau G, Giardina C and Rosenberg DW. (2003). Carcinogenesis, 24, 307-315.
7. Eshleman JR, Casey G, Kochera ME, Sedwick WD, Swinler SE, Veigl ML, Willson JK, Schwartz S and Markowitz SD. (1998). Oncogene, 17, 719-725.
8. Fearnhead NS, Britton MP and Bodmer WF. (2001). Hum. Mol. Genet., 10, 721-733.
9. Fearon ER and Vogelstein B. (1990). Cell, 61, 759-767.
10. Georgiades IB, Curtis LJ, Morris RM, Bird CC and Wyllie AH. (1999). Oncogene, 18, 7933-7940.
11. Goel A, Arnold CN, Niedzwiecki D, Chang DK, Ricciardiello L, Carethers JM, Dowell JM, Wasserman L, Compton C, Mayer RJ, Bertagnolli MM and Boland CR. (2003). Cancer Res., 63, 1608-1614.
12. Guda K, Giardina C, Nambiar P, Cui H and Rosenberg DW. (2001). Mol. Carcinog., 31, 204-213.
13. Haag JD, Brasic GM, Shepel LA, Newton MA, Grubbs CJ, Lubet RA, Kelloff GJ and Gould MN. (1999). Mol. Carcinog., 24, 47-56.
14. Hermsen M, Postma C, Baak J, Weiss M, Rapallo A, Sciutto A, Roemen G, Arenas JW, Williams R, Giaretti W, De Goeij A and Meijer G. (2002). Gastroenterology, 123, 1109-1119.
15. Hoglund M, Gisselsson D, Hansen GB, Sall T, Mitelman F and Nilbert M. (2002). Cancer Res., 62, 5939-5946.
16. Iino H, Jass JR, Simms LA, Young J, Leggett B, Ajioka Y and Watanabe H. (1999). J. Clin. Pathol., 52, 5-9.
17. Jass JR. (2003). J. Pathol., 199, 267-269 author reply 269-70.
18. Jass JR, Biden KG, Cummings MC, Simms LA, Walsh M, Schoch E, Meltzer SJ, Wright C, Searle J, Young J and Leggett BA. (1999). J. Clin. Pathol., 52, 455-460.
19. Jass JR, Walsh MD, Barker M, Simms LA, Young J and Leggett BA. (2002). Eur. J. Cancer, 38, 858-866.
20. Kambara T, Matsubara N, Nakagawa H, Notohara K, Nagasaka T, Yoshino T, Isozaki H, Sharp GB, Shimizu K, Jass J and Tanaka N. (2001). Cancer Res., 61, 7743-7746.
21. Kislitsin D, Lerner A, Rennert G and Lev Z. (2002). Dig. Dis. Sci., 47, 1073-1079.
22. Kohonen-Corish MR, Daniel JJ, te Riele H, Buffinton GD and Dahlstrom JE. (2002). Cancer Res., 62, 2092-2097.
23. Kolligs FT, Bommer G and Goke B. (2002). Digestion, 66, 131-144.
24. Lengauer C, Kinzler KW and Vogelstein B. (1997). Nature, 386, 623-627.
25. Lindblom A. (2001). Curr. Opin. Oncol., 13, 63-69.
26. Liyanage M, Coleman A, du Manoir S, Veldman T, McCormack S, Dickson RB, Barlow C, Wynshaw-Boris A, Janz S, Wienberg J, Ferguson-Smith MA, Schrock E and Ried T. (1996). Nat. Genet., 14, 312-315.
27. Lothe RA, Peltomaki P, Meling GI, Aaltonen LA, Nystrom-Lahti M, Pylkkanen L, Heimdal K, Andersen TI, Moller P and Rognum TO et al. (1993). Cancer Res., 53, 5849-5852.
28. Luceri C, De Filippo C, Caderni G, Gambacciani L, Salvadori M, Giannini A and Dolara P. (2000). Carcinogenesis, 21, 1753-1756.
29. Nambiar PR, Giardina C, Guda K, Aizu W, Raja R and Rosenberg DW. (2002). Cancer Res., 62, 3667-3674.
30. Nambiar PR, Girnun G, Lillo NA, Guda K, Whiteley HE and Rosenberg DW. (2003). Int. J. Oncol., 22, 145-150.
31. Neufeld KL and White RL. (1997). Proc. Natl. Acad. Sci. USA, 94, 3034-3039.
32. Olschwang S, Hamelin R, Laurent-Puig P, Thuille B, De Rycke Y, Li YJ, Muzeau F, Girodet J, Salmon RJ and Thomas G. (1997). Proc. Natl. Acad. Sci. USA, 94, 12122-12127.
33. Rajagopalan H, Nowak MA, Vogelstein B and Lengauer C. (2003). Nat. Rev. Cancer, 3, 695-701.
34. Ried T, Heselmeyer-Haddad K, Blegen H, Schrock E and Auer G. (1999). Genes Chromosomes Cancer, 25, 195-204.
35. Ried T, Knutzen R, Steinbeck R, Blegen H, Schrock E, Heselmeyer K, du Manoir S and Auer G. (1996). Genes Chromosomes Cancer, 15, 234-245.
36. Sheng H, Shao J, Williams CS, Pereira MA, Taketo MM, Oshima M, Reynolds AB, Washington MK, DuBois RN and Beauchamp RD. (1998). Carcinogenesis, 19, 543-549.
37. Sohn KJ, Choi M, Song J, Chan S, Medline A, Gallinger S and Kim YI. (2003). Carcinogenesis, 24, 217-224.
38. Takahashi M, Mutoh M, Kawamori T, Sugimura T and Wakabayashi K. (2000a). Carcinogenesis, 21, 1319-1327.
39. Takahashi M, Nakatsugi S, Sugimura T and Wakabayashi K. (2000b). Carcinogenesis, 21, 1117-1120.
40. Thibodeau SN, Bren G and Schaid D. (1993). Science, 260, 816-819.
41. Tomlinson I, Halford S, Aaltonen L, Hawkins N and Ward R. (2002). J. Pathol., 197, 6-13.
42. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM and Bos JL. (1988). N. Engl. J. Med., 319, 525-532.
43. Walchle C, Diwan BA, Shiao YH and Calvert RJ. (1999). Toxicol. Appl. Pharmacol., 157, 9-15.
44. Wang QS, Papanikolaou A, Sabourin CL and Rosenberg DW. (1998). Carcinogenesis, 19, 2001-2006.
45. Weaver Z, Montagna C, Xu X, Howard T, Gadina M, Brodie SG, Deng CX and Ried T. (2002). Oncogene, 21, 5097-5107.
46. Whitehall VL, Walsh MD, Young J, Leggett BA and Jass JR. (2001). Cancer Res., 61, 827-830.
47. Wong MH, Hermiston ML, Syder AJ and Gordon JI. (1996). Proc. Natl. Acad. Sci. USA, 93, 9588-9593.
48. Young J, Simms LA, Biden KG, Wynter C, Whitehall V, Karamatic R, George J, Goldblatt J, Walpole I, Robin SA, Borten MM, Stitz R, Searle J, McKeone D, Fraser L, Purdie DR, Podger K, Price R, Buttenshaw R, Walsh MD, Barker M, Leggett BA and Jass JR. (2001). Am. J. Pathol., 159, 2107-2116.