Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex

Molecular and Cellular Biology

Volumn 20, Issue 18, 2000, Pages 6806-6815

  Niu, H ^a   Xia, J ^a   Lue, N F ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEASE; RNA DIRECTED DNA POLYMERASE; TELOMERASE;

ARTICLE; DNA SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; TELOMERE; YEAST;

BINDING SITES; CHROMATOGRAPHY, AFFINITY; DNA PRIMERS; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; RNA; RNA-DIRECTED DNA POLYMERASE; SACCHAROMYCES CEREVISIAE; TELOMERASE;

EID: 0033816358     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.18.6806-6815.2000     Document Type: Article

References (37)

1. Telomerases
2. Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytrica trifallax
3. Telomerase in yeast
4. The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex
5. Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation
6. Purification of Tetrahymenu telomerase and cloning of genes encoding the two protein components of the enzyme
7. The RNA component of human telomerase
8. Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates
9. Flexible positioning of the telomerase-associated nuclease leads to preferential elimination of nontelomeric DNA
10. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
11. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
12. Telomerase is processive
13. dGTP-dependent processivity and possible template switching of Euplotes telomerase
14. A mammalian telomerase-associated protein
15. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes
16. An in vitro assay for Saccharomyces telomerase requires EST1
17. Reverse transcriptase motifs in the catalytic subunit of telomerase
18. Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity
19. Identification and characterization of a telomerase activity from Schizosaccharomyces pombe
20. Negative regulation of yeast telomerase activity through an interaction with an upstream region of the DNA primer
21. Telomerase activity in germline and embryonic cells of Xenopus
22. Processing of nontelomeric 3' ends by telomerase: Default template alignment and endonucleolytic cleavage
23. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
24. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
25. Telomerase catalytic subunit homologs from fission yeast and human
26. TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family
27. The telomerase reverse transcriptase: Components and regulation
28. Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal non-processivity in vivo and in vitro
29. Functionally interacting telomerase RNAs in the yeast telomerase complex
30. Identification of a nonprocessive telomerase activity from mouse cells
31. The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes
32. Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiae
33. TLC1:Template RNA component of Saccharomyces cerevisiae telomerase
34. Association of the Est1 protein with telomerase activity in yeast
35. Basic mechanisms of transcription elongation and its regulation
36. Telomeres: Beginning to understand the end