-
1
-
-
0028863151
-
Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase
-
Andrake, M. D., and A. M. Skalka. 1995. Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase. J. Biol. Chem. 270:29299-29306.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29299-29306
-
-
Andrake, M.D.1
Skalka, A.M.2
-
2
-
-
0029087712
-
Analysis of human immunodeficiency virus type 1 integrase mutants
-
Ansari-Lari, M. A., L. A. Donehower, and R. Gibbs. 1995. Analysis of human immunodeficiency virus type 1 integrase mutants. Virology 211:332-335.
-
(1995)
Virology
, vol.211
, pp. 332-335
-
-
Ansari-Lari, M.A.1
Donehower, L.A.2
Gibbs, R.3
-
3
-
-
0035824646
-
Role of the nonspecific DNA-binding region and alpha helices within the core domain of retroviral integrase in selecting target DNA sites for integration
-
Appa, R. S., C.-G. Shin, P. Lee, and S. A. Chow. 2001. Role of the nonspecific DNA-binding region and alpha helices within the core domain of retroviral integrase in selecting target DNA sites for integration. J. Biol. Chem. 276:45848-45855.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45848-45855
-
-
Appa, R.S.1
Shin, C.-G.2
Lee, P.3
Chow, S.A.4
-
4
-
-
1242272071
-
A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: Characterization of a functional nuclear localization signal
-
Armon-Omer, A., A. Graesssmann, and A. Loyter. 2004. A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal. J. Mol. Biol. 336:1117-1128.
-
(2004)
J. Mol. Biol.
, vol.336
, pp. 1117-1128
-
-
Armon-Omer, A.1
Graesssmann, A.2
Loyter, A.3
-
5
-
-
0035947289
-
HIV-1 infection requires a functional integrase NLS
-
Bouyac-Bertoia, M., J. D. Dvorin, R. A. M. Fouchier, Y. Jenkins, B. E. Meyer, L. I. Wu, M. Emerman, and M. H. Malim. 2001. HIV-1 infection requires a functional integrase NLS. Mol. Cell 7:1025-1035.
-
(2001)
Mol. Cell
, vol.7
, pp. 1025-1035
-
-
Bouyac-Bertoia, M.1
Dvorin, J.D.2
Fouchier, R.A.M.3
Jenkins, Y.4
Meyer, B.E.5
Wu, L.I.6
Emerman, M.7
Malim, M.H.8
-
6
-
-
0032846188
-
Structure-based mutagenesis of the human immunodeficiency virus type 1 DNA attachment site: Effects on integration and cDNA synthesis
-
Brown, H. E. V., H. Chen, and A. Engelman. 1999. Structure-based mutagenesis of the human immunodeficiency virus type 1 DNA attachment site: effects on integration and cDNA synthesis. J. Virol. 73:9011-9020.
-
(1999)
J. Virol.
, vol.73
, pp. 9011-9020
-
-
Brown, H.E.V.1
Chen, H.2
Engelman, A.3
-
7
-
-
0029815034
-
Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease
-
Bukovsky, A., and H. Göttlinger. 1996. Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease. J. Virol. 70:6820-6825.
-
(1996)
J. Virol.
, vol.70
, pp. 6820-6825
-
-
Bukovsky, A.1
Göttlinger, H.2
-
8
-
-
0026655897
-
Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase
-
Burke, C. J., G. Sanyal, M. W. Bruner, J. A. Ryan, R. L. LaFemina, H. L. Robbins, A. S. Zeft, C. R. Middaugh, and M. G. Cordingley. 1992. Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase. J. Biol. Chem. 267:9639-9644.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 9639-9644
-
-
Burke, C.J.1
Sanyal, G.2
Bruner, M.W.3
Ryan, J.A.4
Lafemina, R.L.5
Robbins, H.L.6
Zeft, A.S.7
Middaugh, C.R.8
Cordingley, M.G.9
-
9
-
-
0027456715
-
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
-
Bushman, F. D., A. Engelman, I. Palmer, P. Wingfield, and R. Craigie. 1993. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc. Natl. Acad. Sci. USA 90:342S-3432.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
-
-
Bushman, F.D.1
Engelman, A.2
Palmer, I.3
Wingfield, P.4
Craigie, R.5
-
10
-
-
0030986376
-
Solution structure of the N-terminal zinc binding domain of HIV-1 integrase
-
Cai, M., R. Zheng, M. Caffrey, R. Craigie, G. M. Clore, and A. M. Gronenhorn. 1997. Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat. Struct. Biol. 4:567-577.
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 567-577
-
-
Cai, M.1
Zheng, R.2
Caffrey, M.3
Craigie, R.4
Clore, G.M.5
Gronenhorn, A.M.6
-
11
-
-
0029655459
-
Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication
-
Cannon, P. M., E. D. Byles, S. M. Kingsman, and A. J. Kingsman. 1996. Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication. J. Virol. 70:651-657.
-
(1996)
J. Virol.
, vol.70
, pp. 651-657
-
-
Cannon, P.M.1
Byles, E.D.2
Kingsman, S.M.3
Kingsman, A.J.4
-
12
-
-
0034812967
-
Asymmetric processing of human immunodeficiency virus type 1 cDNA in vivo: Implications for functional end coupling during the chemical steps of DNA transposition
-
Chen, H., and A. Engelman. 2001. Asymmetric processing of human immunodeficiency virus type 1 cDNA in vivo: implications for functional end coupling during the chemical steps of DNA transposition. Mol. Cell. Biol. 21:6758-6767.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6758-6767
-
-
Chen, H.1
Engelman, A.2
-
13
-
-
0033546149
-
Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome
-
Chen, H., S.-Q. Wei, and A. Engelman. 1999. Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome. J. Biol. Chem. 274:17358-17364.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17358-17364
-
-
Chen, H.1
Wei, S.-Q.2
Engelman, A.3
-
14
-
-
0034682511
-
Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding
-
Chen, J. C.-H., J. Krucinski, L. J. W. Miercke, J. S. Finer-Moore, A. H. Tang, A. D. Leavitt, and R. M. Stroud. 2000. Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding. Proc. Natl. Acad. Sci. USA 97:8233-8238.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8233-8238
-
-
Chen, J.C.-H.1
Krucinski, J.2
Miercke, L.J.W.3
Finer-Moore, J.S.4
Tang, A.H.5
Leavitt, A.D.6
Stroud, R.M.7
-
15
-
-
0346036088
-
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
-
Cherepanov, P., G. Maertens, P. Proost, B. Devreese, J. Van Beeumen, Y. Engelborghs, E. De Clercq, and Z. Debyser. 2003. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J. Biol. Chem. 278:372-381.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 372-381
-
-
Cherepanov, P.1
Maertens, G.2
Proost, P.3
Devreese, B.4
Van Beeumen, J.5
Engelborghs, Y.6
De Clercq, E.7
Debyser, Z.8
-
16
-
-
85158002042
-
Retroviral DNA integration
-
N. L. Craig, R. Craigie, M. Gellert, and A. M. Lambowitz (ed.). ASM Press, Washington, D.C.
-
Craigie, R. 2002. Retroviral DNA integration, p. 613-630. In N. L. Craig, R. Craigie, M. Gellert, and A. M. Lambowitz (ed.), Mobile DNA II. ASM Press, Washington, D.C.
-
(2002)
Mobile DNA II
, pp. 613-630
-
-
Craigie, R.1
-
18
-
-
0034329417
-
Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses
-
Depienne, C., P. Roques, C. Creminon, L. Fritsch, R. Casseron, D. Dormont, C. Dargemont, and S. Benichou. 2000. Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses. Exp. Cell Res. 260:387-395.
-
(2000)
Exp. Cell Res.
, vol.260
, pp. 387-395
-
-
Depienne, C.1
Roques, P.2
Creminon, C.3
Fritsch, L.4
Casseron, R.5
Dormont, D.6
Dargemont, C.7
Benichou, S.8
-
19
-
-
0242550989
-
Intracellular transport of human immunodeficiency virus type 1 integrase
-
Devroe, E., A. Engelman, and P. A. Silver. 2003. Intracellular transport of human immunodeficiency virus type 1 integrase. J. Cell Sci. 116:4401-4408.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 4401-4408
-
-
Devroe, E.1
Engelman, A.2
Silver, P.A.3
-
20
-
-
0034824775
-
Mapping DNA-binding sites of HIV-1 integrase by protein footprinting
-
Dirac, A. M. G., and J. Kjems. 2001. Mapping DNA-binding sites of HIV-1 integrase by protein footprinting. Eur. J. Biochem. 268:743-751.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 743-751
-
-
Dirac, A.M.G.1
Kjems, J.2
-
21
-
-
0026740842
-
Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 in protein in vitro
-
Drelich, M., R. Wilhelm, and J. Mous. 1992. Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro. Virology 188:459-468.
-
(1992)
Virology
, vol.188
, pp. 459-468
-
-
Drelich, M.1
Wilhelm, R.2
Mous, J.3
-
22
-
-
0036889124
-
Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import
-
Dvorin, J. D., P. Bell, G. G. Maul, M. Yamashita, M. Emerman, and M. H. Malim. 2002. Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import. J. Virol. 76:12087-12096.
-
(2002)
J. Virol.
, vol.76
, pp. 12087-12096
-
-
Dvorin, J.D.1
Bell, P.2
Maul, G.G.3
Yamashita, M.4
Emerman, M.5
Malim, M.H.6
-
23
-
-
0028584269
-
Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases
-
Dyda, F., A. B. Hickman, T. M. Jenkins, A. Engelman, R. Craigie, and D. R. Davies. 1994. Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science 266:1981-1986.
-
(1994)
Science
, vol.266
, pp. 1981-1986
-
-
Dyda, F.1
Hickman, A.B.2
Jenkins, T.M.3
Engelman, A.4
Craigie, R.5
Davies, D.R.6
-
24
-
-
0031260521
-
The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: A three-helix bundle stabilized by zinc
-
Eijkelenboom, A. P., F. M. van den Ent, A. Vos, J. F. Doreleijers, K. Hard, T. D. Tullius, R. H. Plasterk, R. Kaptein, and R. Boelens. 1997. The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc. Curr. Biol. 7:739-746.
-
(1997)
Curr. Biol.
, vol.7
, pp. 739-746
-
-
Eijkelenboom, A.P.1
Van Den Ent, F.M.2
Vos, A.3
Doreleijers, J.F.4
Hard, K.5
Tullius, T.D.6
Plasterk, R.H.7
Kaptein, R.8
Boelens, R.9
-
25
-
-
0029145047
-
The DNA-binding domain of HIV-1 integrase has an SH3-like fold
-
Egkelenboom, A. P. A. M., R. A. Puras Lutzke, R. Boelens, R. H. A. Plasterk, R. Kaptein, and K. Hard. 1995. The DNA-binding domain of HIV-1 integrase has an SH3-like fold. Nat. Struct. Biol. 2:807-810.
-
(1995)
Nat. Struct. Biol.
, vol.2
, pp. 807-810
-
-
Egkelenboom, A.P.A.M.1
Puras Lutzke, R.A.2
Boelens, R.3
Plasterk, R.H.A.4
Kaptein, R.5
Hard, K.6
-
26
-
-
0032617446
-
In vivo analysis of retroviral integrase structure and function
-
Engelman, A. 1999. In vivo analysis of retroviral integrase structure and function. Adv. Virus Res. 52:411-4126.
-
(1999)
Adv. Virus Res.
, vol.52
, pp. 411-4126
-
-
Engelman, A.1
-
27
-
-
0042164434
-
The roles of cellular factors in retroviral integration
-
Engelman, A. 2003. The roles of cellular factors in retroviral integration. Curr. Top. Microbiol. Immunol. 281:209-238.
-
(2003)
Curr. Top. Microbiol. Immunol.
, vol.281
, pp. 209-238
-
-
Engelman, A.1
-
28
-
-
0027179694
-
Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex
-
Engelman, A., F. D. Bushman, and R. Craigie. 1993. Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex. EMBO J. 12:3269-3275.
-
(1993)
EMBO J.
, vol.12
, pp. 3269-3275
-
-
Engelman, A.1
Bushman, F.D.2
Craigie, R.3
-
29
-
-
0026649557
-
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
-
Engelman, A., and R. Craigie. 1992. Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J. Virol. 66:6361-6369.
-
(1992)
J. Virol.
, vol.66
, pp. 6361-6369
-
-
Engelman, A.1
Craigie, R.2
-
30
-
-
0028915128
-
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
-
Engelman, A., G. Englund, J. M. Orenstein, M. A. Martin, and R. Craigie. 1995. Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J. Virol. 69:2729-2736.
-
(1995)
J. Virol.
, vol.69
, pp. 2729-2736
-
-
Engelman, A.1
Englund, G.2
Orenstein, J.M.3
Martin, M.A.4
Craigie, R.5
-
31
-
-
0028067324
-
The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding
-
Engelman, A., A. B. Hickman, and R. Craigie. 1994. The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. J. Virol. 68:5911-5917.
-
(1994)
J. Virol.
, vol.68
, pp. 5911-5917
-
-
Engelman, A.1
Hickman, A.B.2
Craigie, R.3
-
32
-
-
0032189652
-
Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction
-
Esposito, D., and R. Craigie. 1998. Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction. EMBO J. 17:5832-5843.
-
(1998)
EMBO J.
, vol.17
, pp. 5832-5843
-
-
Esposito, D.1
Craigie, R.2
-
33
-
-
0030792182
-
Complementation of integrase function in HIV-1 virions
-
Fletcher, T. M., III, M. A. Soares, S. McPhearson, H. Hui, M. Wiskerchen, M. A. Muesing, G. M. Shaw, A. D. Leavitt, J. D. Boeke, and B. H. Hahn. 1997. Complementation of integrase function in HIV-1 virions. EMBO J. 16:5123-5138.
-
(1997)
EMBO J.
, vol.16
, pp. 5123-5138
-
-
Fletcher III, T.M.1
Soares, M.A.2
McPhearson, S.3
Hui, H.4
Wiskerchen, M.5
Muesing, M.A.6
Shaw, G.M.7
Leavitt, A.D.8
Boeke, J.D.9
Hahn, B.H.10
-
34
-
-
0030987672
-
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway
-
Gallay, P., T. Hope, D. Chin, and D. Trono. 1997. HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway. Proc. Natl. Acad. Sci. USA 94:9825-9830.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9825-9830
-
-
Gallay, P.1
Hope, T.2
Chin, D.3
Trono, D.4
-
35
-
-
0035796559
-
Human immunodeficiency virus type 1 integrase: Arrangement of protein domains in active cDNA complexes
-
Gao, K., S. L. Butler, and F. Bushman. 2001. Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes. EMBO J. 20:3565-3576.
-
(2001)
EMBO J.
, vol.20
, pp. 3565-3576
-
-
Gao, K.1
Butler, S.L.2
Bushman, F.3
-
36
-
-
0030764902
-
The core domain of HIV-1 integrase recognizes key features of its DNA substrates
-
Gerton, J. L., and P. O. Brown. 1997. The core domain of HIV-1 integrase recognizes key features of its DNA substrates. J. Biol. Chem. 272:25809-25815.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25809-25815
-
-
Gerton, J.L.1
Brown, P.O.2
-
37
-
-
0031949592
-
Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions
-
Gerton, J. L., S. Ohgi, M. Olsen, J. DeRisi, and P. O. Brown. 1998. Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions. J. Virol. 72:5046-5055.
-
(1998)
J. Virol.
, vol.72
, pp. 5046-5055
-
-
Gerton, J.L.1
Ohgi, S.2
Olsen, M.3
DeRisi, J.4
Brown, P.O.5
-
38
-
-
0001469617
-
Retroviridae: The retroviruses and their replication
-
D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.). Lippincott Williams & Wilkins, Philadelphia, Pa.
-
Goff, S. P. 2001. Retroviridae: the retroviruses and their replication, p. 1871-1939. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, Pa.
-
(2001)
Fields Virology, 4th Ed.
, pp. 1871-1939
-
-
Goff, S.P.1
-
39
-
-
0034908087
-
Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection
-
Harper, A. L., L. M. Skinner, M. Sudol, and M. Katzman. 2001. Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection. J. Virol. 75:7756-7762.
-
(2001)
J. Virol.
, vol.75
, pp. 7756-7762
-
-
Harper, A.L.1
Skinner, L.M.2
Sudol, M.3
Katzman, M.4
-
40
-
-
2342648913
-
Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins
-
Hehl, E. A., P. Joshi, G. V. Kalpana, and V. R. Prasad. 2004. Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins. J. Virol. 78:5056-5067.
-
(2004)
J. Virol.
, vol.78
, pp. 5056-5067
-
-
Hehl, E.A.1
Joshi, P.2
Kalpana, G.V.3
Prasad, V.R.4
-
41
-
-
0030875813
-
Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking
-
Heuer, T. S., and P. O. Brown. 1997. Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking. Biochemistry 36:10655-10665.
-
(1997)
Biochemistry
, vol.36
, pp. 10655-10665
-
-
Heuer, T.S.1
Brown, P.O.2
-
42
-
-
6344219975
-
Evaluation of the functional involvement of human immunodeficiency virus type 1 integrase in nuclear import of viral cDNA during acute infection
-
Ikeda, T., H. Nishitsuji, X. Zhou, N. Nara, T. Ohashi, M. Kannagi, and T. Masuda. 2004. Evaluation of the functional involvement of human immunodeficiency virus type 1 integrase in nuclear import of viral cDNA during acute infection. J. Virol. 78:11563-11573.
-
(2004)
J. Virol.
, vol.78
, pp. 11563-11573
-
-
Ikeda, T.1
Nishitsuji, H.2
Zhou, X.3
Nara, N.4
Ohashi, T.5
Kannagi, M.6
Masuda, T.7
-
43
-
-
0029980485
-
A soluble active mutant of HIV-1 integrase: Involvement of both the core and the C-terminal domains in multimerization
-
Jenkins, T. M., A. Engelman, R. Ghirlando, and R. Craigie. 1996. A soluble active mutant of HIV-1 integrase: involvement of both the core and the C-terminal domains in multimerization. J. Biol. Chem. 271:7712-7718.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 7712-7718
-
-
Jenkins, T.M.1
Engelman, A.2
Ghirlando, R.3
Craigie, R.4
-
44
-
-
0030828521
-
Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking
-
Jenkins, T. M., D. Esposito, A. Engelman, and R. Craigie. 1997. Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking. EMBO J. 16:6849-6859.
-
(1997)
EMBO J.
, vol.16
, pp. 6849-6859
-
-
Jenkins, T.M.1
Esposito, D.2
Engelman, A.3
Craigie, R.4
-
45
-
-
0033526768
-
Isolation and characterization of an oligomerization-negative mutant of HIV-1 integrase
-
Kalpana, G. V., A. Reicin, G. S. W. Cheng, M. Sorin, S. Paik, and S. P. Goff. 1999. Isolation and characterization of an oligomerization-negative mutant of HIV-1 integrase. Virology 259:274-285.
-
(1999)
Virology
, vol.259
, pp. 274-285
-
-
Kalpana, G.V.1
Reicin, A.2
Cheng, G.S.W.3
Sorin, M.4
Paik, S.5
Goff, S.P.6
-
46
-
-
0024347717
-
Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: Evidence for differential gene expression
-
Kim, S. Y., R. Byrn, J. Groopman, and D. Baltimore. 1989. Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression. J. Virol. 63:3708-3713.
-
(1989)
J. Virol.
, vol.63
, pp. 3708-3713
-
-
Kim, S.Y.1
Byrn, R.2
Groopman, J.3
Baltimore, D.4
-
47
-
-
23244443593
-
-
Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, N. Mex.
-
Kuiken, C. L., B. Foley, E. O. Freed, B. Hahn, B. Korber, P. A. Marx, F. McCutchan, J. W. Mellors, and S. Wolinsky. 2002. HIV sequence compendium 2002, report no. LA-UR 03-3564. Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, N. Mex.
-
(2002)
HIV Sequence Compendium 2002, Report No. LA-UR 03-3564
-
-
Kuiken, C.L.1
Foley, B.2
Freed, E.O.3
Hahn, B.4
Korber, B.5
Marx, P.A.6
McCutchan, F.7
Mellors, J.W.8
Wolinsky, S.9
-
48
-
-
0031060369
-
Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases
-
Kukolj, G., K. Jones, and A. Skalka. 1997. Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases. J. Virol. 71:843-847.
-
(1997)
J. Virol.
, vol.71
, pp. 843-847
-
-
Kukolj, G.1
Jones, K.2
Skalka, A.3
-
49
-
-
0026719238
-
Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases
-
Kulkosky, J., K. S. Jones, R. A. Katz, J. P. Mack, and A. M. Skalka. 1992. Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Mol. Cell. Biol. 12:2331-2338.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2331-2338
-
-
Kulkosky, J.1
Jones, K.S.2
Katz, R.A.3
Mack, J.P.4
Skalka, A.M.5
-
50
-
-
0030030041
-
Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection
-
Leavitt, A. D., G. Robles, N. Alesandro, and H. E. Varmus. 1996. Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection. J. Virol. 70:721-728.
-
(1996)
J. Virol.
, vol.70
, pp. 721-728
-
-
Leavitt, A.D.1
Robles, G.2
Alesandro, N.3
Varmus, H.E.4
-
51
-
-
0027470432
-
Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro
-
Leavitt, A. D., L. Shiue, and H. E. Varmus. 1993. Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. J. Biol. Chem. 268:2113-2119.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2113-2119
-
-
Leavitt, A.D.1
Shiue, L.2
Varmus, H.E.3
-
53
-
-
0036838711
-
Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import
-
Limón, A., E. Devroe, R. Lu, H. Z. Ghory, P. A. Silver, and A. Engelman. 2002. Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import. J. Virol. 76:10598-10607.
-
(2002)
J. Virol.
, vol.76
, pp. 10598-10607
-
-
Limón, A.1
Devroe, E.2
Lu, R.3
Ghory, H.Z.4
Silver, P.A.5
Engelman, A.6
-
54
-
-
0036889161
-
Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap
-
Limón, A., N. Nakajima, R. Lu, H. Z. Ghory, and A. Engelman. 2002. Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap. J. Virol. 76:12078-12086.
-
(2002)
J. Virol.
, vol.76
, pp. 12078-12086
-
-
Limón, A.1
Nakajima, N.2
Lu, R.3
Ghory, H.Z.4
Engelman, A.5
-
55
-
-
4143092604
-
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
-
Llano, M., M. Vanegas, O. Fregoso, D. Saenz, S. Chung, M. Peretz, and E. M. Poeschla. 2004. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J. Virol. 78:9524-9537.
-
(2004)
J. Virol.
, vol.78
, pp. 9524-9537
-
-
Llano, M.1
Vanegas, M.2
Fregoso, O.3
Saenz, D.4
Chung, S.5
Peretz, M.6
Poeschla, E.M.7
-
56
-
-
0029116747
-
Solution structure of the DNA binding domain of HIV-1 integrase
-
Lodi, P. J., J. A. Ernst, J. Kuszewski, A. B. Hickman, A. Engelman, R. Craigie, G. M. Clore, and A. M. Gronenborn. 1995. Solution structure of the DNA binding domain of HIV-1 integrase. Biochemistry 34:9826-9833.
-
(1995)
Biochemistry
, vol.34
, pp. 9826-9833
-
-
Lodi, P.J.1
Ernst, J.A.2
Kuszewski, J.3
Hickman, A.B.4
Engelman, A.5
Craigie, R.6
Clore, G.M.7
Gronenborn, A.M.8
-
57
-
-
8644226108
-
Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a post-nuclear entry step of human immunodeficiency virus type 1 replication
-
Lu, R., A. Limón, E. Devroe, P. A. Silver, and A. Engelman. 2004. Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a post-nuclear entry step of human immunodeficiency virus type 1 replication. J. Virol. 78:12735-12746.
-
(2004)
J. Virol.
, vol.78
, pp. 12735-12746
-
-
Lu, R.1
Limón, A.2
Devroe, E.3
Silver, P.A.4
Engelman, A.5
-
58
-
-
13444269378
-
Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase
-
Lu, R., A. Limón, H. Z. Ghory, and A. Engelman. 2005. Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase. J. Virol. 79:2493-2505.
-
(2005)
J. Virol.
, vol.79
, pp. 2493-2505
-
-
Lu, R.1
Limón, A.2
Ghory, H.Z.3
Engelman, A.4
-
59
-
-
0347949575
-
Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages
-
Lu, R., N. Nakajima, W. Hofmann, M. Benkirane, K.-T. Jeang, J. Sodroski, and A. Engelman. 2004. Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages. J. Virol. 78:658-668.
-
(2004)
J. Virol.
, vol.78
, pp. 658-668
-
-
Lu, R.1
Nakajima, N.2
Hofmann, W.3
Benkirane, M.4
Jeang, K.-T.5
Sodroski, J.6
Engelman, A.7
-
60
-
-
4043112782
-
Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75
-
Maertens, G., P. Cherepanov, Z. Debyser, Y. Engelborghs, and A. Engelman. 2004. Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75. J. Biol. Chem. 279:33421-33429.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33421-33429
-
-
Maertens, G.1
Cherepanov, P.2
Debyser, Z.3
Engelborghs, Y.4
Engelman, A.5
-
61
-
-
0041856142
-
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
-
Maertens, G., P. Cherepanov, W. Pluymers, K. Busschots, E. De Clercq, Z. Debyser, and Y. Engelborghs. 2003. LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. J. Biol. Chem. 278:33528-33539.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33528-33539
-
-
Maertens, G.1
Cherepanov, P.2
Pluymers, W.3
Busschots, K.4
De Clercq, E.5
Debyser, Z.6
Engelborghs, Y.7
-
62
-
-
0026081040
-
Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis
-
Mumm, S. R., and D. P. Grandgenett. 1991. Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis. J. Virol. 65:1160-1167.
-
(1991)
J. Virol.
, vol.65
, pp. 1160-1167
-
-
Mumm, S.R.1
Grandgenett, D.P.2
-
63
-
-
0034863355
-
Human immunodeficiency virus type 1 replication in the absence of integrase-mediated DNA recombination: Definition of permissive and nonpermissive T-cell lines
-
Nakajima, N., R. Lu, and A. Engelman. 2001. Human immunodeficiency virus type 1 replication in the absence of integrase-mediated DNA recombination: definition of permissive and nonpermissive T-cell lines. J. Virol. 75:7944-7955.
-
(2001)
J. Virol.
, vol.75
, pp. 7944-7955
-
-
Nakajima, N.1
Lu, R.2
Engelman, A.3
-
64
-
-
0033912323
-
The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA
-
Petit, C., O. Schwartz, and F. Mammano. 2000. The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA. J. Virol. 74:7119-7126.
-
(2000)
J. Virol.
, vol.74
, pp. 7119-7126
-
-
Petit, C.1
Schwartz, O.2
Mammano, F.3
-
65
-
-
0033032198
-
Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase
-
Petit, C., O. Schwartz, and F. Mammano. 1999. Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase. J. Virol. 73:5079-5088.
-
(1999)
J. Virol.
, vol.73
, pp. 5079-5088
-
-
Petit, C.1
Schwartz, O.2
Mammano, F.3
-
66
-
-
0033526522
-
Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein
-
Pluymers, W., P. Cherepanov, D. Schols, E. De Clercq, and Z. Debyser. 1999. Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein. Virology 258:327-332.
-
(1999)
Virology
, vol.258
, pp. 327-332
-
-
Pluymers, W.1
Cherepanov, P.2
Schols, D.3
De Clercq, E.4
Debyser, Z.5
-
67
-
-
0038757649
-
Reversion of the lethal phenotype of an HIV-1 integrase mutant virus by overexpression of the same integrase mutant protein
-
Priet, S., J.-M. Navarro, G. Querat, and J. Sire. 2003. Reversion of the lethal phenotype of an HIV-1 integrase mutant virus by overexpression of the same integrase mutant protein. J. Biol. Chem. 278:20724-20730.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20724-20730
-
-
Priet, S.1
Navarro, J.-M.2
Querat, G.3
Sire, J.4
-
68
-
-
0001166515
-
Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: Critical residues for protein Oligomerization and DNA binding
-
Puras Lutzke, R. A., and R. H. A. Plasterk. 1998. Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein Oligomerization and DNA binding. J. Virol. 72:4841-4848.
-
(1998)
J. Virol.
, vol.72
, pp. 4841-4848
-
-
Puras Lutzke, R.A.1
Plasterk, R.H.A.2
-
69
-
-
0028034050
-
Characterization of the minimal DNA-binding domain of the HIV integrase protein
-
Puras Lutzke, R. A., C. Vink, and R. H. A. Plasterk. 1994. Characterization of the minimal DNA-binding domain of the HIV integrase protein. Nucleic Acids Res. 22:4125-4131.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4125-4131
-
-
Puras Lutzke, R.A.1
Vink, C.2
Plasterk, R.H.A.3
-
70
-
-
0029978462
-
Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation
-
Quillent, C., A. M. Borman, S. Paulous, C. Dauguet, and F. Clavel. 1996. Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation. Virology 219:29-36.
-
(1996)
Virology
, vol.219
, pp. 29-36
-
-
Quillent, C.1
Borman, A.M.2
Paulous, S.3
Dauguet, C.4
Clavel, F.5
-
71
-
-
0035343895
-
Comparative architecture of transposase and integrase complexes
-
Rice, P. A., and T. A. Baker. 2001. Comparative architecture of transposase and integrase complexes. Nat. Struct. Biol. 8:302-307.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 302-307
-
-
Rice, P.A.1
Baker, T.A.2
-
72
-
-
0030932575
-
Central core domain of retroviral integrase is responsible for target site selection
-
Shibagaki, Y., and S. A. Chow. 1997. Central core domain of retroviral integrase is responsible for target site selection. J. Biol. Chem. 272:8361-8369.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8361-8369
-
-
Shibagaki, Y.1
Chow, S.A.2
-
73
-
-
0036201681
-
Molecular biology of lentivirus-mediated gene transfer
-
Stevenson, M. 2002. Molecular biology of lentivirus-mediated gene transfer. Curr. Top. Microbiol. Immunol. 261:1-30.
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.261
, pp. 1-30
-
-
Stevenson, M.1
-
74
-
-
8644231282
-
Human cell proteins and human immunodeficiency virus DNA integration
-
Turlure, F., E. Devroe, P. A. Silver, and A. Engelman. 2004. Human cell proteins and human immunodeficiency virus DNA integration. Front. Biosci. 9:3187-3208.
-
(2004)
Front. Biosci.
, vol.9
, pp. 3187-3208
-
-
Turlure, F.1
Devroe, E.2
Silver, P.A.3
Engelman, A.4
-
75
-
-
0031965842
-
Mutational scan of the human immunodeficiency virus type 2 integrase protein
-
van den Ent, F. M. I., A. Vos, and R. H. A. Plasterk. 1998. Mutational scan of the human immunodeficiency virus type 2 integrase protein. J. Virol. 72:3916-3924.
-
(1998)
J. Virol.
, vol.72
, pp. 3916-3924
-
-
Van Den Ent, F.M.I.1
Vos, A.2
Plasterk, R.H.A.3
-
76
-
-
0026668776
-
Mutational analysis of the integrase protein of human immunodeficiency virus type 2
-
van Gent, D. C., A. A. M. O. Groeneger, and R. H. A. Plasterk. 1992. Mutational analysis of the integrase protein of human immunodeficiency virus type 2. Proc. Natl. Acad. Sci. USA 89:9598-9602.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9598-9602
-
-
Van Gent, D.C.1
Groeneger, A.A.M.O.2
Plasterk, R.H.A.3
-
77
-
-
0027246609
-
Complementation between HIV integrase proteins mutated in different domains
-
van Gent, D. C., C. Vink, A. A. M. O. Groeneger, and R. H. A. Plasterk. 1993. Complementation between HIV integrase proteins mutated in different domains. EMBO J. 12:3261-3267.
-
(1993)
EMBO J.
, vol.12
, pp. 3261-3267
-
-
Van Gent, D.C.1
Vink, C.2
Groeneger, A.A.M.O.3
Plasterk, R.H.A.4
-
78
-
-
0027210608
-
Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein
-
Vink, C., A. M. Oude Groeneger, and R. H. A. Plasterk. 1993. Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein. Nucleic Acids Res. 21:1419-1425.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 1419-1425
-
-
Vink, C.1
Oude Groeneger, A.M.2
Plasterk, R.H.A.3
-
79
-
-
0037126629
-
Structure of a two-domain fragment of HIV-1 integrase: Implications for domain organization in the intact protein
-
Wang, J.-Y., H. Ling, W. Yang, and R. Craigie. 2001. Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J. 20:7333-7343.
-
(2001)
EMBO J.
, vol.20
, pp. 7333-7343
-
-
Wang, J.-Y.1
Ling, H.2
Yang, W.3
Craigie, R.4
-
80
-
-
0028924020
-
Human immunodeficiency virus type 1 integrase: Effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
-
Wiskerchen, M., and M. A. Muesing. 1995. Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells. J. Virol. 69:376-386.
-
(1995)
J. Virol.
, vol.69
, pp. 376-386
-
-
Wiskerchen, M.1
Muesing, M.A.2
-
81
-
-
0026539155
-
Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein
-
Woerner, A. M., M. Klutch, J. G. Levin, and C. J. Marcus-Sekura. 1992. Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein. AIDS Res. Hum. Retrovir. 8:297-304.
-
(1992)
AIDS Res. Hum. Retrovir.
, vol.8
, pp. 297-304
-
-
Woerner, A.M.1
Klutch, M.2
Levin, J.G.3
Marcus-Sekura, C.J.4
-
82
-
-
0027205243
-
Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis
-
Woerner, A. M., and C. J. Marcus-Sekura. 1993. Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis. Nucleic Acids Res. 21:3507-3511.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3507-3511
-
-
Woerner, A.M.1
Marcus-Sekura, C.J.2
-
83
-
-
0037383126
-
Subcellular localization of feline immunodeficiency virus integrase and mapping of its karyophilic determinant
-
Woodward, C. L., Y. Wang, W. J. Dixon, H. Htun, and S. A. Chow. 2003. Subcellular localization of feline immunodeficiency virus integrase and mapping of its karyophilic determinant. J. Virol. 77:4516-4527.
-
(2003)
J. Virol.
, vol.77
, pp. 4516-4527
-
-
Woodward, C.L.1
Wang, Y.2
Dixon, W.J.3
Htun, H.4
Chow, S.A.5
-
84
-
-
0030851908
-
Functional RT and in incorporated into HIV-1 particles independently of the Gag/Pol precursor protein
-
Wu, X., H. Liu, H. Xiao, J. A. Conway, E. Hunter, and J. C. Kappes. 1997. Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein. EMBO J. 16:5113-5122.
-
(1997)
EMBO J.
, vol.16
, pp. 5113-5122
-
-
Wu, X.1
Liu, H.2
Xiao, H.3
Conway, J.A.4
Hunter, E.5
Kappes, J.C.6
-
85
-
-
1242297002
-
Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance
-
Yung, E., M. Sorin, E.-J. Wang, S. Perumal, D. Ott, and G. V. Kalpana. 2004. Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance. J. Virol. 78:2222-2231.
-
(2004)
J. Virol.
, vol.78
, pp. 2222-2231
-
-
Yung, E.1
Sorin, M.2
Wang, E.-J.3
Perumal, S.4
Ott, D.5
Kalpana, G.V.6
-
86
-
-
0030478950
-
Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity
-
Zheng, R., T. M. Jenkins, and R. Craigie. 1996. Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity. Proc. Natl. Acad. Sci. USA 93:13659-13664.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13659-13664
-
-
Zheng, R.1
Jenkins, T.M.2
Craigie, R.3
-
87
-
-
2342541832
-
Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase
-
Zhu, K., C. Dobard, and S. A. Chow. 2004. Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase. J. Virol. 78:5045-5055.
-
(2004)
J. Virol.
, vol.78
, pp. 5045-5055
-
-
Zhu, K.1
Dobard, C.2
Chow, S.A.3
|