-
1
-
-
0035884710
-
Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure
-
JOHNSON RW, KREIS H, OBERBAUER R, et al: Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation 72:777-786, 2001
-
(2001)
Transplantation
, vol.72
, pp. 777-786
-
-
Johnson, R.W.1
Kreis, H.2
Oberbauer, R.3
-
2
-
-
0038299000
-
Sirolimus: Its discovery, biological properties, and mechanism of action
-
SEHGAL SN: Sirolimus: Its discovery, biological properties, and mechanism of action. Transplant Proc 35:S7-S14, 2003
-
(2003)
Transplant Proc
, vol.35
-
-
Sehgal, S.N.1
-
3
-
-
0032054816
-
The mRNA 5′ cap-binding protein eIF4E and control of cell growth
-
SONENBERG N, GINGRAS AC: The mRNA 5′ cap-binding protein eIF4E and control of cell growth. Curr Opin Cell Biol 10:268-275, 1998
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 268-275
-
-
Sonenberg, N.1
Gingras, A.C.2
-
4
-
-
0034644525
-
TOR, a central controller of cell growth
-
SCHMELZLE T, HALL MN: TOR, a central controller of cell growth. Cell 103:253-262, 2000
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
5
-
-
0032485937
-
Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability
-
HASHEMOLHOSSEINI S, NAGAMINE Y, MORLEY SJ, et al: Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability. J Biol Chem 273:14424-14429, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 14424-14429
-
-
Hashemolhosseini, S.1
Nagamine, Y.2
Morley, S.J.3
-
6
-
-
0037207525
-
Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin
-
DECKER T, HIPP S, RINGSHAUSEN I, et al: Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. Blood 101:278-285, 2003
-
(2003)
Blood
, vol.101
, pp. 278-285
-
-
Decker, T.1
Hipp, S.2
Ringshausen, I.3
-
7
-
-
0031594842
-
The upregulation of p27Kip1 by rapamycin results in G1 arrest in exponentially growing T-cell lines
-
KAWAMATA S, SAKAIDA H, HORI T, et al: The upregulation of p27Kip1 by rapamycin results in G1 arrest in exponentially growing T-cell lines. Blood 91:561-569, 1998
-
(1998)
Blood
, vol.91
, pp. 561-569
-
-
Kawamata, S.1
Sakaida, H.2
Hori, T.3
-
8
-
-
0036130039
-
The impact of delayed graft function on the long-term outcome of renal transplantation
-
GEDDES CC, WOO YM, JARDINE AG: The impact of delayed graft function on the long-term outcome of renal transplantation. J Nephrol 15:17-21, 2002
-
(2002)
J Nephrol
, vol.15
, pp. 17-21
-
-
Geddes, C.C.1
Woo, Y.M.2
Jardine, A.G.3
-
9
-
-
0037378763
-
Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use
-
SMITH KD, WRENSHALL LE, NICOSIA RF, et al: Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use. J Am Soc Nephrol 14:1037-1045, 2003
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1037-1045
-
-
Smith, K.D.1
Wrenshall, L.E.2
Nicosia, R.F.3
-
10
-
-
0038666511
-
Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation
-
MCTAGGART RA, GOTTLIEB D, BROOKS J, et al: Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. Am J Transplant 3:416-423, 2003
-
(2003)
Am J Transplant
, vol.3
, pp. 416-423
-
-
Mctaggart, R.A.1
Gottlieb, D.2
Brooks, J.3
-
11
-
-
0038666506
-
Sirolimus delays renal allograft recovery
-
DAVIS C: Sirolimus delays renal allograft recovery. Am J Transplant 3:363-365, 2003
-
(2003)
Am J Transplant
, vol.3
, pp. 363-365
-
-
Davis, C.1
-
12
-
-
0030723151
-
Acute renal failure: Growth factors, cell therapy, and gene therapy
-
HUMES HD, MACKAY SM, FUNKE AJ, et al: Acute renal failure: Growth factors, cell therapy, and gene therapy. Proc Assoc Am Physicians 109:547-557, 1997
-
(1997)
Proc Assoc Am Physicians
, vol.109
, pp. 547-557
-
-
Humes, H.D.1
Mackay, S.M.2
Funke, A.J.3
-
13
-
-
0028273536
-
Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells
-
WITZGALL R, BROWN D, SCHWARZ C, BONVENTRE JV: Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 93:2175-2188, 1994
-
(1994)
J Clin Invest
, vol.93
, pp. 2175-2188
-
-
Witzgall, R.1
Brown, D.2
Schwarz, C.3
Bonventre, J.V.4
-
14
-
-
0037324549
-
Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo
-
TANG S, LEUNG JC, ABE K, et al: Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo. J Clin Invest 111:515-527, 2003
-
(2003)
J Clin Invest
, vol.111
, pp. 515-527
-
-
Tang, S.1
Leung, J.C.2
Abe, K.3
-
15
-
-
0021357180
-
Tissue culture of human kidney epithelial cells of proximal tubule origin
-
DETRISAC CJ, SENS MA, GARVIN AJ, et al: Tissue culture of human kidney epithelial cells of proximal tubule origin. Kidney Int 25:383-390, 1984
-
(1984)
Kidney Int
, vol.25
, pp. 383-390
-
-
Detrisac, C.J.1
Sens, M.A.2
Garvin, A.J.3
-
16
-
-
0142244215
-
Beta4 integrin and laminin 5 are aberrantly expressed in polycystic kidney disease: Role in increased cell adhesion and migration
-
JOLY D, MOREL V, HUMMEL A, et al: Beta4 integrin and laminin 5 are aberrantly expressed in polycystic kidney disease: Role in increased cell adhesion and migration. Am J Pathol 163:1791-1800, 2003
-
(2003)
Am J Pathol
, vol.163
, pp. 1791-1800
-
-
Joly, D.1
Morel, V.2
Hummel, A.3
-
17
-
-
0035132656
-
Flow cytometric immunodissection of the human distal tubule and cortical collecting duct system
-
HELBERT MF, DAUWE SE, DE BROE ME: Flow cytometric immunodissection of the human distal tubule and cortical collecting duct system. Kidney Int 59:554-564, 2001
-
(2001)
Kidney Int
, vol.59
, pp. 554-564
-
-
Helbert, M.F.1
Dauwe, S.E.2
De Broe, M.E.3
-
19
-
-
3342933376
-
Downregulation of the cellular adhesion molecule Thy-1 (CD90) by cytomegalovirus infection of human fibroblasts
-
LEIS M, MARSCHALL M, STAMMINGER T: Downregulation of the cellular adhesion molecule Thy-1 (CD90) by cytomegalovirus infection of human fibroblasts. J Gen Virol 85:1995-2000, 2004
-
(2004)
J Gen Virol
, vol.85
, pp. 1995-2000
-
-
Leis, M.1
Marschall, M.2
Stamminger, T.3
-
20
-
-
0028983892
-
Elevated D-glucose concentrations modulate TGF-beta 1 synthesis by human cultured renal proximal tubular cells. The permissive role of platelet-derived growth factor
-
PHILLIPS AO, STEADMAN R, TOPLEY N, WILLIAMS JD: Elevated D-glucose concentrations modulate TGF-beta 1 synthesis by human cultured renal proximal tubular cells. The permissive role of platelet-derived growth factor. Am J Pathol 147:362-374, 1995
-
(1995)
Am J Pathol
, vol.147
, pp. 362-374
-
-
Phillips, A.O.1
Steadman, R.2
Topley, N.3
Williams, J.D.4
-
21
-
-
0021717125
-
Inhibitory effect of 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole on a protein kinase
-
ZANDOMENI R, WEINMANN R: Inhibitory effect of 5,6-dichloro-1-beta-D- ribofuranosylbenzimidazole on a protein kinase. J Biol Chem 259:14804-14811, 1984
-
(1984)
J Biol Chem
, vol.259
, pp. 14804-14811
-
-
Zandomeni, R.1
Weinmann, R.2
-
22
-
-
0032618597
-
Regulation of mammalian ribosomal gene transcription by RNA polymerase I
-
GRUMMT I: Regulation of mammalian ribosomal gene transcription by RNA polymerase I. Prog Nucleic Acid Res Mol Biol; 62:109-154, 1999
-
(1999)
Prog Nucleic Acid Res Mol Biol
, vol.62
, pp. 109-154
-
-
Grummt, I.1
-
24
-
-
0038607932
-
Regulation of the cyclin D3 promoter by E2F1
-
MA Y, YUAN J, HUANG M, et al: Regulation of the cyclin D3 promoter by E2F1. J Biol Chem 278:16770-16776, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 16770-16776
-
-
Ma, Y.1
Yuan, J.2
Huang, M.3
-
25
-
-
0036278326
-
Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex
-
BERGAMETTI F, SITTERLIN D, TRANSY C: Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex. J Virol 76:6495-6501, 2002
-
(2002)
J Virol
, vol.76
, pp. 6495-6501
-
-
Bergametti, F.1
Sitterlin, D.2
Transy, C.3
-
26
-
-
0027382336
-
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
-
HELIN K, HARLOW E, FATTAEY A: Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol Cell Biol 13:6501-6508, 1993
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6501-6508
-
-
Helin, K.1
Harlow, E.2
Fattaey, A.3
-
27
-
-
0034789534
-
Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells
-
LIEBERTHAL W, FUHRO R, ANDRY CC, et al: Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells. Am J Physiol Renal Physiol 281:F693-706, 2001
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Lieberthal, W.1
Fuhro, R.2
Andry, C.C.3
-
28
-
-
0034004155
-
Cell cycle regulatory proteins in renal disease: Role in hypertrophy, proliferation, and apoptosis
-
SHANKLAND SJ, WOLF G: Cell cycle regulatory proteins in renal disease: Role in hypertrophy, proliferation, and apoptosis. Am J Physiol Renal Physiol 278:F515-529, 2000
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Shankland, S.J.1
Wolf, G.2
-
29
-
-
0030470754
-
The role of phosphoinositide 3-kinase in insulin signalling
-
SHEPHERD PR, NAVE BT, O'RAHILLY S: The role of phosphoinositide 3-kinase in insulin signalling. J Mol Endocrinol 17:175-184, 1996
-
(1996)
J Mol Endocrinol
, vol.17
, pp. 175-184
-
-
Shepherd, P.R.1
Nave, B.T.2
O'Rahilly, S.3
-
30
-
-
0029968940
-
Functional analysis of the human cyclin D2 and cyclin D3 promoters
-
BROOKS AR, SHIFFMAN D, CHAN CS, et al: Functional analysis of the human cyclin D2 and cyclin D3 promoters. J Biol Chem 271:9090-9099, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 9090-9099
-
-
Brooks, A.R.1
Shiffman, D.2
Chan, C.S.3
-
31
-
-
0027336002
-
p70s6k function is essential for G1 progression
-
LANE HA, FERNANDEZ A, LAMB NJ, THOMAS G: p70s6k function is essential for G1 progression. Nature 363:170-172, 1993
-
(1993)
Nature
, vol.363
, pp. 170-172
-
-
Lane, H.A.1
Fernandez, A.2
Lamb, N.J.3
Thomas, G.4
-
32
-
-
0039700194
-
p70 S6 kinase-mediated protein synthesis is a critical step for vascular endothelial cell proliferation
-
VINALS F, CHAMBARD JC, POUYSSEGUR J: p70 S6 kinase-mediated protein synthesis is a critical step for vascular endothelial cell proliferation. J Biol Chem 274:26776-26782, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 26776-26782
-
-
Vinals, F.1
Chambard, J.C.2
Pouyssegur, J.3
-
33
-
-
0028876806
-
Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells
-
MARX SO, JAYARAMAN T, GO LO, MARKS AR: Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells. Circ Res 76:412-417, 1995
-
(1995)
Circ Res
, vol.76
, pp. 412-417
-
-
Marx, S.O.1
Jayaraman, T.2
Go, L.O.3
Marks, A.R.4
-
34
-
-
0037830758
-
Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression
-
NELSEN CJ, RICKHEIM DG, TUCKER MM, et al: Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression. J Biol Chem 278:25853-25858, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 25853-25858
-
-
Nelsen, C.J.1
Rickheim, D.G.2
Tucker, M.M.3
-
35
-
-
0033178702
-
Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K path way in human pancreatic cancer cells
-
GREWE M, GANSAUGE F, SCHMID RM, et al: Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K path way in human pancreatic cancer cells. Cancer Res 59:3581-3587, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 3581-3587
-
-
Grewe, M.1
Gansauge, F.2
Schmid, R.M.3
-
36
-
-
0037457348
-
Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN
-
MISAWA A, HOSOI H, TSUCHIYA K, SUGIMOTO T: Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN. Int J Cancer 104:233-237, 2003
-
(2003)
Int J Cancer
, vol.104
, pp. 233-237
-
-
Misawa, A.1
Hosoi, H.2
Tsuchiya, K.3
Sugimoto, T.4
-
37
-
-
0032491579
-
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway
-
MUISE-HELMERICKS RC, GRIMES HL, BELLACOSA A, et al: Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. J Biol Chem 273:29864-29872, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 29864-29872
-
-
Muise-Helmericks, R.C.1
Grimes, H.L.2
Bellacosa, A.3
-
38
-
-
0034682805
-
Stem cell factor/c-kit upregulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia
-
FENG LX, RAVINDRANATH N, DYM M: Stem cell factor/c-kit upregulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia. J Biol Chem 275:25572-25576, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 25572-25576
-
-
Feng, L.X.1
Ravindranath, N.2
Dym, M.3
-
39
-
-
0027441885
-
IL-2-dependent induction of G1 cyclins in primary T cells is not blocked by rapamycin or cyclosporin A
-
TURNER JM: IL-2-dependent induction of G1 cyclins in primary T cells is not blocked by rapamycin or cyclosporin A. Int immunol 5:1199-1209, 1993
-
(1993)
Int Immunol
, vol.5
, pp. 1199-1209
-
-
Turner, J.M.1
-
40
-
-
0037108682
-
Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors
-
KENERSON HL, AICHER LD, TRUE LD, YEUNG RS: Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. Cancer Res 62:5645-5650, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 5645-5650
-
-
Kenerson, H.L.1
Aicher, L.D.2
True, L.D.3
Yeung, R.S.4
-
41
-
-
0033711708
-
Regulation of G1 cyclin-dependent kinases in the mammalian cell cycle
-
EKHOLM SV, REED SI: Regulation of G1 cyclin-dependent kinases in the mammalian cell cycle. Curr Opin Cell Biol 12:676-684, 2000
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 676-684
-
-
Ekholm, S.V.1
Reed, S.I.2
-
42
-
-
0027336491
-
Mammalian G1 cyclins
-
SHERR CJ: Mammalian G1 cyclins. Cell 73:1059-1065, 1993
-
(1993)
Cell
, vol.73
, pp. 1059-1065
-
-
Sherr, C.J.1
-
43
-
-
0035196663
-
The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae
-
ALBIG AR, DECKER CJ: The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae. Mol Biol Cell 12:3428-3438, 2001
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3428-3438
-
-
Albig, A.R.1
Decker, C.J.2
-
44
-
-
0030974986
-
Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3′ untranslated region
-
BANHOLZER R, NAIR AP, HIRSCH HH, et al: Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3′ untranslated region. Mol Cell Biol 17:3254-3260, 1997
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3254-3260
-
-
Banholzer, R.1
Nair, A.P.2
Hirsch, H.H.3
-
45
-
-
0037097743
-
Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway
-
GHOSH P, BUCHHOLZ MA, YANO S, et al: Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. Blood 99:4517-4524, 2002
-
(2002)
Blood
, vol.99
, pp. 4517-4524
-
-
Ghosh, P.1
Buchholz, M.A.2
Yano, S.3
-
46
-
-
0028788194
-
AU-rich elements: Characterization and importance in mRNA degradation
-
CHEN CY, SHYU AB: AU-rich elements: Characterization and importance in mRNA degradation. Trends Biochem Sci 20:465-470, 1995
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 465-470
-
-
Chen, C.Y.1
Shyu, A.B.2
-
47
-
-
0030915898
-
Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k
-
JEFFERIES HB, FUMAGALLI S, DENNIS PB, et al: Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k. EMBO J 16:3693-3704, 1997
-
(1997)
EMBO J
, vol.16
, pp. 3693-3704
-
-
Jefferies, H.B.1
Fumagalli, S.2
Dennis, P.B.3
-
48
-
-
0025726295
-
The high cost of delayed graft function in cadaveric renal transplantation
-
ROSENTHAL JT, DANOVITCH GM, WILKINSON A, ETTENGER RB: The high cost of delayed graft function in cadaveric renal transplantation. Transplantation 51:1115-1118, 1991
-
(1991)
Transplantation
, vol.51
, pp. 1115-1118
-
-
Rosenthal, J.T.1
Danovitch, G.M.2
Wilkinson, A.3
Ettenger, R.B.4
-
49
-
-
0032572746
-
Delayed graft function does not reduce the survival of renal transplant allografts
-
MARCEN R, OROFINO L, PASCUAL J, et al: Delayed graft function does not reduce the survival of renal transplant allografts. Transplantation 66:461-466, 1998
-
(1998)
Transplantation
, vol.66
, pp. 461-466
-
-
Marcen, R.1
Orofino, L.2
Pascual, J.3
-
50
-
-
0032911110
-
Early graft function and patient survival following cadaveric renal transplantation
-
Woo YM, JARDINE AG, CLARK AF, et al: Early graft function and patient survival following cadaveric renal transplantation. Kidney Int 55:692-699, 1999
-
(1999)
Kidney Int
, vol.55
, pp. 692-699
-
-
Woo, Y.M.1
Jardine, A.G.2
Clark, A.F.3
-
51
-
-
0033852745
-
Delayed graft function influences renal function, but not survival
-
BOOM H, MALLAT MJ, DE FIJTER JW, et al: Delayed graft function influences renal function, but not survival. Kidney Int 58:859-866, 2000
-
(2000)
Kidney Int
, vol.58
, pp. 859-866
-
-
Boom, H.1
Mallat, M.J.2
De Fijter, J.W.3
-
52
-
-
0034102411
-
Time dependency of factors affecting renal allograft survival
-
PROMMOOL S, JHANGRI GS, COCKFIELD SM, HALLORAN PF: Time dependency of factors affecting renal allograft survival. J Am Soc Nephrol 11:565-573, 2000
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 565-573
-
-
Prommool, S.1
Jhangri, G.S.2
Cockfield, S.M.3
Halloran, P.F.4
-
53
-
-
0027639210
-
The nephrotoxicity of FK506 as compared with cyclosporine
-
MCCAULEY J: The nephrotoxicity of FK506 as compared with cyclosporine. Curr Opin Nephrol Hypertens 2:662-669, 1993
-
(1993)
Curr Opin Nephrol Hypertens
, vol.2
, pp. 662-669
-
-
Mccauley, J.1
-
54
-
-
33746530366
-
Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study
-
The Rapamune US Study Group
-
KAHAN BD: Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study. The Rapamune US Study Group. Lancet 356:194-202, 2000
-
(2000)
Lancet
, vol.356
, pp. 194-202
-
-
Kahan, B.D.1
|