메뉴 건너뛰기




Volumn 146, Issue 8, 2005, Pages 3221-3223

Learning new tricks from an old dog: The processing of the intracellular precursor of the Luteinizing Hormone Receptor (LHR) into the mature cell-surface LHR is a regulated process

Author keywords

[No Author keywords available]

Indexed keywords

GONADOTROPIN; LUTEINIZING HORMONE RECEPTOR;

EID: 23044505437     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-0590     Document Type: Short Survey
Times cited : (6)

References (41)
  • 3
    • 0027158153 scopus 로고
    • The lutropin/choriogonadotropin (LH/CG) receptor. . . 4 years later
    • Segaloff DL, Ascoli M 1993 The lutropin/choriogonadotropin (LH/CG) receptor. . . 4 years later. Endocr Rev 14:324-347
    • (1993) Endocr Rev , vol.14 , pp. 324-347
    • Segaloff, D.L.1    Ascoli, M.2
  • 4
    • 0036217072 scopus 로고    scopus 로고
    • The lutropin/choriogonadotropin receptor, a 2002 perspective
    • Ascoli M, Fanelli F, Segaloff DL 2002 The lutropin/choriogonadotropin receptor, a 2002 perspective. Endocr Rev 23:141-174
    • (2002) Endocr Rev , vol.23 , pp. 141-174
    • Ascoli, M.1    Fanelli, F.2    Segaloff, D.L.3
  • 6
    • 0032247323 scopus 로고    scopus 로고
    • The thyrotropin (TSH) hormone receptor: Interaction with TSH and autoantibodies
    • Rapoport B, Chazenbalk D, Jaume JC, McLachlan SM 1998 The thyrotropin (TSH) hormone receptor: interaction with TSH and autoantibodies. Endocr Rev 19:673-716
    • (1998) Endocr Rev , vol.19 , pp. 673-716
    • Rapoport, B.1    Chazenbalk, D.2    Jaume, J.C.3    McLachlan, S.M.4
  • 7
    • 1542316313 scopus 로고    scopus 로고
    • A molecular dissection of the glycoprotein hormone receptors
    • Vassart G, Pardo L, Costagliola S 2004 A molecular dissection of the glycoprotein hormone receptors. Trends Biochem Sci 29:119-126
    • (2004) Trends Biochem Sci , vol.29 , pp. 119-126
    • Vassart, G.1    Pardo, L.2    Costagliola, S.3
  • 8
    • 0033361906 scopus 로고    scopus 로고
    • Naturally occurring mutations of the luteinizing-hormone receptor: Lessons learned about reproductive physiology and G protein-coupled receptors
    • Latronico AC, Segaloff DL 1999 Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors. Am J Hum Genet 65:949-958
    • (1999) Am J Hum Genet , vol.65 , pp. 949-958
    • Latronico, A.C.1    Segaloff, D.L.2
  • 9
    • 0033711033 scopus 로고    scopus 로고
    • Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function
    • Themmen APN, Huhtaniemi IT 2000 Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function. Endocr Rev 21:551-583
    • (2000) Endocr Rev , vol.21 , pp. 551-583
    • Themmen, A.P.N.1    Huhtaniemi, I.T.2
  • 10
    • 0032506018 scopus 로고    scopus 로고
    • Impairing follicle-stimulating hormone (FSH) signaling in vivo: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
    • Dierich A, Sairam MR, Monaco L, Fimia GM, Gansmuller A, LeMeur M, Sassone-Corsi PS 1998 Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance. Proc Natl Acad Sci USA 95:13612-13617
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13612-13617
    • Dierich, A.1    Sairam, M.R.2    Monaco, L.3    Fimia, G.M.4    Gansmuller, A.5    LeMeur, M.6    Sassone-Corsi, P.S.7
  • 11
    • 0035133266 scopus 로고    scopus 로고
    • Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice
    • Zhang F-P, Poutanen M, Wilbertz J, Huhtaniemi I 2001 Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice. Mol Endocrinol 15:172-183
    • (2001) Mol Endocrinol , vol.15 , pp. 172-183
    • Zhang, F.-P.1    Poutanen, M.2    Wilbertz, J.3    Huhtaniemi, I.4
  • 12
    • 0035136888 scopus 로고    scopus 로고
    • Targeted disruption of luteinizing hormone/human chorionic gonadotropin receptor gene
    • Lei ZM, Mishra S, Zou W, Xu B, Foltz M, Li X, Rao CV 2001 Targeted disruption of luteinizing hormone/human chorionic gonadotropin receptor gene. Mol Endocrinol 15:184-200
    • (2001) Mol Endocrinol , vol.15 , pp. 184-200
    • Lei, Z.M.1    Mishra, S.2    Zou, W.3    Xu, B.4    Foltz, M.5    Li, X.6    Rao, C.V.7
  • 13
    • 12744280744 scopus 로고    scopus 로고
    • Structure of the human follicle-stimulating hormone in complex with its receptors
    • Fan QR, Hendricson WA 2005 Structure of the human follicle-stimulating hormone in complex with its receptors. Nature 433:269-277
    • (2005) Nature , vol.433 , pp. 269-277
    • Fan, Q.R.1    Hendricson, W.A.2
  • 14
    • 0035013450 scopus 로고    scopus 로고
    • An overview of the past, present, and future of non-gonadal LH/hCG actions in reproductive biology and medicine
    • Rao CV 2001 An overview of the past, present, and future of non-gonadal LH/hCG actions in reproductive biology and medicine. Semin Reprod Med 19:7-17
    • (2001) Semin Reprod Med , vol.19 , pp. 7-17
    • Rao, C.V.1
  • 15
    • 0002961243 scopus 로고    scopus 로고
    • The beginning of a new era in reproductive biology and medicine: Expression of low levels of functional luteinizing hormone hormone/human chorionic gonadotropin receptors in nongonadal tissues
    • RaoCV1996 The beginning of a new era in reproductive biology and medicine: expression of low levels of functional luteinizing hormone hormone/human chorionic gonadotropin receptors in nongonadal tissues. J Physiol Pharmacol 47:41-53
    • (1996) J Physiol Pharmacol , vol.47 , pp. 41-53
    • Rao, C.V.1
  • 16
    • 0037155001 scopus 로고    scopus 로고
    • Consequences of targeted inactivation of LH receptors
    • Rao CV, Lei ZM 2002 Consequences of targeted inactivation of LH receptors. Mol Cell Endocrinol 187:57-67
    • (2002) Mol Cell Endocrinol , vol.187 , pp. 57-67
    • Rao, C.V.1    Lei, Z.M.2
  • 17
    • 0035195939 scopus 로고    scopus 로고
    • Multiple novel roles of luteinizing hormone
    • Rao CV 2001 Multiple novel roles of luteinizing hormone. Fertil Steril 76:1097-1100
    • (2001) Fertil Steril , vol.76 , pp. 1097-1100
    • Rao, C.V.1
  • 18
    • 23044484256 scopus 로고    scopus 로고
    • Expression of the mature luteinizing hormone receptor in rodent urogenital and adrenal tissues is developmentally regulated at a posttranslational level
    • Apaja PM, Aatsinki JT, Rajaniemi HJ, Petäjä-Repo UE 2005 Expression of the mature luteinizing hormone receptor in rodent urogenital and adrenal tissues is developmentally regulated at a posttranslational level. Endocrinology 146:3224-3232
    • (2005) Endocrinology , vol.146 , pp. 3224-3232
    • Apaja, P.M.1    Aatsinki, J.T.2    Rajaniemi, H.J.3    Petäjä-Repo, U.E.4
  • 19
    • 1242272013 scopus 로고    scopus 로고
    • Constitutive and agonist-dependent self-association of the cell surface human lutropin receptor
    • Tao Y-X, Johnson NB, Segaloff DL 2004 Constitutive and agonist-dependent self-association of the cell surface human lutropin receptor. J Biol Chem 279:5904-5914
    • (2004) J Biol Chem , vol.279 , pp. 5904-5914
    • Tao, Y.-X.1    Johnson, N.B.2    Segaloff, D.L.3
  • 22
    • 0027093726 scopus 로고
    • Identification and characterization of a luteinizing hormone/chorionic gonadotropin (LH/CG) receptor precursor in a human kidney cell line stably transfected with the rat luteal LH/CG receptor complementary DNA
    • Hipkin RW, Sánchez-Yagüe J, Ascoli M 1992 Identification and characterization of a luteinizing hormone/chorionic gonadotropin (LH/CG) receptor precursor in a human kidney cell line stably transfected with the rat luteal LH/CG receptor complementary DNA. Mol Endocrinol 6:2210-2218
    • (1992) Mol Endocrinol , vol.6 , pp. 2210-2218
    • Hipkin, R.W.1    Sánchez-Yagüe, J.2    Ascoli, M.3
  • 23
    • 0345826101 scopus 로고    scopus 로고
    • Identification and Structural Characterization of the Neuronal Luteinizing Hormone Receptor Associated with Sensory Systems
    • Apaja PM, Harju KT, Aatsinki JT, Petaja-Repo UE, Rajaniemi HJ 2004 Identification and Structural Characterization of the Neuronal Luteinizing Hormone Receptor Associated with Sensory Systems. J Biol Chem 279:1899-1906
    • (2004) J Biol Chem , vol.279 , pp. 1899-1906
    • Apaja, P.M.1    Harju, K.T.2    Aatsinki, J.T.3    Petaja-Repo, U.E.4    Rajaniemi, H.J.5
  • 24
    • 0023258361 scopus 로고
    • Visualization of the rat ovarian lutropin receptor by ligand blotting
    • Keinanen KP, Kellokumpu S, Rajaniemi HJ 1987 Visualization of the rat ovarian lutropin receptor by ligand blotting. Mol Cell Endocrinol 49:33-38
    • (1987) Mol Cell Endocrinol , vol.49 , pp. 33-38
    • Keinanen, K.P.1    Kellokumpu, S.2    Rajaniemi, H.J.3
  • 25
    • 0023644957 scopus 로고
    • Purification and partial characterization of rat ovarian lutropin receptor
    • Keinanen KP, Kellokumpu S, Metsikko MK, Rajaniemi HJ 1987 Purification and partial characterization of rat ovarian lutropin receptor. J Biol Chem 262:7920-7926
    • (1987) J Biol Chem , vol.262 , pp. 7920-7926
    • Keinanen, K.P.1    Kellokumpu, S.2    Metsikko, M.K.3    Rajaniemi, H.J.4
  • 26
    • 0033645593 scopus 로고    scopus 로고
    • Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor
    • Min L, Ascoli M 2000 Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor. Mol Endocrinol 14:1797-1810
    • (2000) Mol Endocrinol , vol.14 , pp. 1797-1810
    • Min, L.1    Ascoli, M.2
  • 27
    • 0032512441 scopus 로고    scopus 로고
    • Transfected cells express mostly the intracellular precursor of the lutropin/choriogonadotropin receptor but this precursor binds choriogonadotropin with high affinity
    • Fabritz J, Ryan S, Ascoli M 1998 Transfected cells express mostly the intracellular precursor of the lutropin/choriogonadotropin receptor but this precursor binds choriogonadotropin with high affinity. Biochemistry 37:664-672
    • (1998) Biochemistry , vol.37 , pp. 664-672
    • Fabritz, J.1    Ryan, S.2    Ascoli, M.3
  • 28
    • 0030948572 scopus 로고    scopus 로고
    • The six N-linked carbohydrates of the lutropin/choriogonadotropin receptor are not absolutely required for correct folding, cell surface expression, hormone binding or signal transduction
    • Davis DP, Rozell TG, Liu X, Segaloff DL 1997 The six N-linked carbohydrates of the lutropin/choriogonadotropin receptor are not absolutely required for correct folding, cell surface expression, hormone binding or signal transduction. Mol Endocrinol 11:550-562
    • (1997) Mol Endocrinol , vol.11 , pp. 550-562
    • Davis, D.P.1    Rozell, T.G.2    Liu, X.3    Segaloff, D.L.4
  • 29
    • 0031046907 scopus 로고    scopus 로고
    • Post-translational processing in the Golgi plays a critical role in the trafficking of the luteinizing hormone/human chorionic gonadotropin receptor to the cell surface
    • Bradbury FA, Kawate N, Foster CM, Menon KMJ 1997 Post-translational processing in the Golgi plays a critical role in the trafficking of the luteinizing hormone/human chorionic gonadotropin receptor to the cell surface. J Biol Chem 272:5921-5926
    • (1997) J Biol Chem , vol.272 , pp. 5921-5926
    • Bradbury, F.A.1    Kawate, N.2    Foster, C.M.3    Menon, K.M.J.4
  • 30
    • 0028872763 scopus 로고
    • The lutropin/choriogonadotropin (LH/CG) receptor is palmitoylated at intracellular cysteine residues
    • Zhu H, Wang H, Ascoli M 1995 The lutropin/choriogonadotropin (LH/CG) receptor is palmitoylated at intracellular cysteine residues. Mol Endocrinol 9:141-150
    • (1995) Mol Endocrinol , vol.9 , pp. 141-150
    • Zhu, H.1    Wang, H.2    Ascoli, M.3
  • 31
    • 0032567352 scopus 로고    scopus 로고
    • Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/choriogonadotropin receptor
    • Min K-S, Liu X, Fabritz J, Jaquette J, Abell AN, AscoliM1998 Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/choriogonadotropin receptor. J Biol Chem 273:34911-34919
    • (1998) J Biol Chem , vol.273 , pp. 34911-34919
    • Min, K.-S.1    Liu, X.2    Fabritz, J.3    Jaquette, J.4    Abell, A.N.5    Ascoli, M.6
  • 32
    • 0034607465 scopus 로고    scopus 로고
    • p38JAB1 Binds to the intracellular precursor of the lutropin/ choriogonadotropin receptor and promotes its degradation
    • Li S, Liu X, Ascoli M 2000 p38JAB1 Binds to the intracellular precursor of the lutropin/choriogonadotropin receptor and promotes its degradation. J Biol Chem 275:13386-13393
    • (2000) J Biol Chem , vol.275 , pp. 13386-13393
    • Li, S.1    Liu, X.2    Ascoli, M.3
  • 33
    • 0031734361 scopus 로고    scopus 로고
    • Association of gonadotropin receptor precursors with the protein folding chaperone calnexin
    • Rozell TG, Davis DP, Chai Y, Segaloff DL 1998 Association of gonadotropin receptor precursors with the protein folding chaperone calnexin. Endocrinology 139:1588-1593
    • (1998) Endocrinology , vol.139 , pp. 1588-1593
    • Rozell, T.G.1    Davis, D.P.2    Chai, Y.3    Segaloff, D.L.4
  • 34
    • 0030043737 scopus 로고    scopus 로고
    • Deletions of portions of the extracellular loops of the lutropin/choriogonadotropin receptor decrease the binding affinity for ovine luteinizing hormone, but not for human choriogonadotropin, by preventing the formation of mature cell surface receptor
    • Abell A, Liu X, Segaloff DL 1996 Deletions of portions of the extracellular loops of the lutropin/choriogonadotropin receptor decrease the binding affinity for ovine luteinizing hormone, but not for human choriogonadotropin, by preventing the formation of mature cell surface receptor. J Biol Chem 271:4518-4527
    • (1996) J Biol Chem , vol.271 , pp. 4518-4527
    • Abell, A.1    Liu, X.2    Segaloff, D.L.3
  • 35
    • 1642268837 scopus 로고    scopus 로고
    • Regulation of luteinizing hormone/human chorionic gonadotropin receptor expression: A perspective
    • Menon KMJ, Munshi UM, Clouser CL, Nair AK 2004 Regulation of luteinizing hormone/human chorionic gonadotropin receptor expression: a perspective. Biol Reprod 70:861-866
    • (2004) Biol Reprod , vol.70 , pp. 861-866
    • Menon, K.M.J.1    Munshi, U.M.2    Clouser, C.L.3    Nair, A.K.4
  • 36
    • 0029742472 scopus 로고    scopus 로고
    • Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice
    • Kumar TR, Wang Y, Matzuk MM 1996 Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice. Endocrinology 137:4210-4216
    • (1996) Endocrinology , vol.137 , pp. 4210-4216
    • Kumar, T.R.1    Wang, Y.2    Matzuk, M.M.3
  • 37
    • 0030787593 scopus 로고    scopus 로고
    • Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin-a subunit promoter/SV40 T-antigen fusion gene
    • Kananen K, Rillianawati Paukku T, Markkula M, Rainio E-M, Huhtaniemi IT 1997 Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin-a subunit promoter/SV40 T-antigen fusion gene. Endocrinology 138:3521-3531
    • (1997) Endocrinology , vol.138 , pp. 3521-3531
    • Kananen, K.1    Rillianawati Paukku, T.2    Markkula, M.3    Rainio, E.-M.4    Huhtaniemi, I.T.5
  • 38
    • 0032230319 scopus 로고    scopus 로고
    • Direct luteinizing hormone action triggers adrenocortical tumorigenesis in castrated mice transgenic for the murine inhibin α-subunit promoter/simian virus 40 T-antigen fusion gene
    • Rilianawati, Paukku T, Kero J, Zhang F-P, Rahman N, Kananen K, Huhtaniemi I 1998 Direct luteinizing hormone action triggers adrenocortical tumorigenesis in castrated mice transgenic for the murine inhibin α-subunit promoter/simian virus 40 T-antigen fusion gene. Mol Cell Endocrinol 12:801-809
    • (1998) Mol Cell Endocrinol , vol.12 , pp. 801-809
    • Rilianawati1    Paukku, T.2    Kero, J.3    Zhang, F.-P.4    Rahman, N.5    Kananen, K.6    Huhtaniemi, I.7
  • 40
    • 0032734209 scopus 로고    scopus 로고
    • Leuprolide acetate therapy in luteinizing hormone-dependent Cushing's syndrome
    • Lacroix A, Hamet P, Boutin JM 1999 Leuprolide acetate therapy in luteinizing hormone-dependent Cushing's syndrome. New Engl J Med 341:1577-1581
    • (1999) New Engl J Med , vol.341 , pp. 1577-1581
    • Lacroix, A.1    Hamet, P.2    Boutin, J.M.3
  • 41
    • 0035118956 scopus 로고    scopus 로고
    • Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome
    • Lacroix A, N'Diaye N, Tremblay J, Hamet P 2001 Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome. Endocr Rev 22:75-110
    • (2001) Endocr Rev , vol.22 , pp. 75-110
    • Lacroix, A.1    N'Diaye, N.2    Tremblay, J.3    Hamet, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.