메뉴 건너뛰기




Volumn 11, Issue 5, 1997, Pages 550-562

The six N-linked carbohydrates of the lutropin/choriogonadotropin receptor are not absolutely required for correct folding, cell surface expression, hormone binding, or signal transduction

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; CHORIONIC GONADOTROPIN; FOLLITROPIN RECEPTOR; LUTEINIZING HORMONE; TUNICAMYCIN;

EID: 0030948572     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.5.9927     Document Type: Article
Times cited : (76)

References (54)
  • 1
    • 0027158153 scopus 로고
    • The lutropin/choriogonadotropin (LH/CG) receptor-4 years later
    • Segaloff DL, Ascoli M 1993 The lutropin/choriogonadotropin (LH/CG) receptor-4 years later. Endocr Rev 14:324-347
    • (1993) Endocr Rev , vol.14 , pp. 324-347
    • Segaloff, D.L.1    Ascoli, M.2
  • 2
    • 0027458346 scopus 로고
    • High expression of the hormone binding active extracellular domain (1-294) of rat lutropin receptor in Escherichia coll
    • Chen W, Bahl OP 1993 High expression of the hormone binding active extracellular domain (1-294) of rat lutropin receptor in Escherichia coll. Mol Cell Endocrinol 91:35-41
    • (1993) Mol Cell Endocrinol , vol.91 , pp. 35-41
    • Chen, W.1    Bahl, O.P.2
  • 3
    • 0025646717 scopus 로고
    • Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity
    • Xie YB, Wang H, Segaloff DL 1990 Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity. J Biol Chem 265:21411-21414
    • (1990) J Biol Chem , vol.265 , pp. 21411-21414
    • Xie, Y.B.1    Wang, H.2    Segaloff, D.L.3
  • 4
    • 0028097211 scopus 로고
    • Hormone binding properties and glycosylation pattern of a recombinant form of the extracellular domain of the LH/CG receptor expressed in mammalian cells
    • Thomas DM, Segaloff DL 1994 Hormone binding properties and glycosylation pattern of a recombinant form of the extracellular domain of the LH/CG receptor expressed in mammalian cells. Endocrinology 135: 1902-1912
    • (1994) Endocrinology , vol.135 , pp. 1902-1912
    • Thomas, D.M.1    Segaloff, D.L.2
  • 5
    • 0025201419 scopus 로고
    • Intronic nature of the rat luteinizing hormone receptor gene defines a soluble receptor subspecies with hormone binding activity
    • Tsai-Morris CH, Buczko E, Wang W, Dufau ML 1990 Intronic nature of the rat luteinizing hormone receptor gene defines a soluble receptor subspecies with hormone binding activity. J Biol Chem 265: 19385-19388
    • (1990) J Biol Chem , vol.265 , pp. 19385-19388
    • Tsai-Morris, C.H.1    Buczko, E.2    Wang, W.3    Dufau, M.L.4
  • 6
    • 0025759135 scopus 로고
    • Exons 1-10 of the rat LH receptor encode a high affinity hormone binding site and exon 11 encodes G-protein modulation and a potential second hormone binding site
    • Ji I, Ji TH 1991 Exons 1-10 of the rat LH receptor encode a high affinity hormone binding site and exon 11 encodes G-protein modulation and a potential second hormone binding site. Endocrinology 128:2648-2650
    • (1991) Endocrinology , vol.128 , pp. 2648-2650
    • Ji, I.1    Ji, T.H.2
  • 7
    • 0025847496 scopus 로고
    • Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity
    • Braun T, Schofield PR, Sprengel R 1991 Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. EMBO J 10:1885-1890
    • (1991) EMBO J , vol.10 , pp. 1885-1890
    • Braun, T.1    Schofield, P.R.2    Sprengel, R.3
  • 9
    • 0028883286 scopus 로고
    • Identification of the sites of N-linked glycosylation on the follicle-stimulating hormone (FSH) receptor and assessment of their role in FSH receptor function
    • Davis D, Liu X, Segaloff DL 1995 Identification of the sites of N-linked glycosylation on the follicle-stimulating hormone (FSH) receptor and assessment of their role in FSH receptor function. Mol Endocrinol 9:159-170
    • (1995) Mol Endocrinol , vol.9 , pp. 159-170
    • Davis, D.1    Liu, X.2    Segaloff, D.L.3
  • 10
    • 0028157562 scopus 로고
    • A recombinant extracellular domain of the thyrotropin (TSH) receptor binds TSH in the absence of membranes
    • Seetharamaiah GS, Kurosky A, Desai RK, Dallas JS, Prabhakar BS 1994 A recombinant extracellular domain of the thyrotropin (TSH) receptor binds TSH in the absence of membranes. Endocrinology 134:549-554
    • (1994) Endocrinology , vol.134 , pp. 549-554
    • Seetharamaiah, G.S.1    Kurosky, A.2    Desai, R.K.3    Dallas, J.S.4    Prabhakar, B.S.5
  • 11
    • 0027300390 scopus 로고
    • High affinity binding of thyrotropin to the extracellular domain of its receptor transfected in chinese hamster ovary cells
    • Shi Y, Zou M, Parhar RS, Farid NR 1993 High affinity binding of thyrotropin to the extracellular domain of its receptor transfected in chinese hamster ovary cells. Thyroid 3:129-133
    • (1993) Thyroid , vol.3 , pp. 129-133
    • Shi, Y.1    Zou, M.2    Parhar, R.S.3    Farid, N.R.4
  • 12
    • 0026782387 scopus 로고
    • Expression of recombinant human follicle-stimulating hormone receptor: Species specific ligand binding, signal transduction, and identification of multiple ovarian messenger ribonucleic acid transcripts
    • Tilly JL, Aihara T, Nishimori K, Jia X-C, Billig H, Kowalski KI, Perlas EA, Hsueh AJW 1992 Expression of recombinant human follicle-stimulating hormone receptor: species specific ligand binding, signal transduction, and identification of multiple ovarian messenger ribonucleic acid transcripts. Endocrinology 131:799-806
    • (1992) Endocrinology , vol.131 , pp. 799-806
    • Tilly, J.L.1    Aihara, T.2    Nishimori, K.3    Jia, X.-C.4    Billig, H.5    Kowalski, K.I.6    Perlas, E.A.7    Hsueh, A.J.W.8
  • 13
    • 0025237466 scopus 로고
    • The testicular receptor for follicle stimulating hormone: Structure and functional expression of cloned cDNA
    • Sprengel R, Braun T, Nikolics K, Segaloff DL, Seeburg PH 1990 The testicular receptor for follicle stimulating hormone: structure and functional expression of cloned cDNA. Mol Endocrinol 4:525-530
    • (1990) Mol Endocrinol , vol.4 , pp. 525-530
    • Sprengel, R.1    Braun, T.2    Nikolics, K.3    Segaloff, D.L.4    Seeburg, P.H.5
  • 14
    • 0024581111 scopus 로고
    • The follicle-stimulating hormone (FSH) receptor in testis: Interaction with FSH, mechanism of signal transduction, and properties of the purified receptor
    • Reichert LE, Jr, Dattatreyamurty B 1989 The follicle-stimulating hormone (FSH) receptor in testis: interaction with FSH, mechanism of signal transduction, and properties of the purified receptor. Biol Reprod 40:13-26
    • (1989) Biol Reprod , vol.40 , pp. 13-26
    • Reichert Jr., L.E.1    Dattatreyamurty, B.2
  • 15
    • 0028245033 scopus 로고
    • Follitropin (FSH) and a phorbol ester stimulate the phosphorylation of the FSH receptor in intact cells
    • Quintana J, Hipkin RW, Sanchez-Yague J, Ascoli M 1994 Follitropin (FSH) and a phorbol ester stimulate the phosphorylation of the FSH receptor in intact cells. J Biol Chem 269:8772-8779
    • (1994) J Biol Chem , vol.269 , pp. 8772-8779
    • Quintana, J.1    Hipkin, R.W.2    Sanchez-Yague, J.3    Ascoli, M.4
  • 16
    • 0024503418 scopus 로고
    • Homologous desensitization of ovarian luteinizing hormone/human chorionic gonadotropin-responsive adenylyl cyclase is dependent upon GTP
    • Ekstrom RC, Hunzicker-Dunn M 1989 Homologous desensitization of ovarian luteinizing hormone/human chorionic gonadotropin-responsive adenylyl cyclase is dependent upon GTP. Endocrinology 124:956-963
    • (1989) Endocrinology , vol.124 , pp. 956-963
    • Ekstrom, R.C.1    Hunzicker-Dunn, M.2
  • 17
    • 0001897295 scopus 로고
    • The stimulation of adenylyl cyclase and cAMP-dependent protein kinases in luteinizing hormone actions
    • Ascoli M (ed) CRC Press, Boca Raton, FL
    • Hunzicker-Dunn M, Birnbaumer L 1985 The stimulation of adenylyl cyclase and cAMP-dependent protein kinases in luteinizing hormone actions. In: Ascoli M (ed) Luteinizing Hormone Action and Receptors. CRC Press, Boca Raton, FL, pp 57-134
    • (1985) Luteinizing Hormone Action and Receptors , pp. 57-134
    • Hunzicker-Dunn, M.1    Birnbaumer, L.2
  • 18
    • 0027405071 scopus 로고
    • Biochemical properties of the agonist-induced desensitization of the follicle-stimulating hormone and luteinizing hormone/ chorionic gonadotropin-responsive adenylyl cyclase in cells expressing the recombinant gonadotropin receptors
    • Sanchez-Yague J, Hipkin RW, Ascoli M 1993 Biochemical properties of the agonist-induced desensitization of the follicle-stimulating hormone and luteinizing hormone/ chorionic gonadotropin-responsive adenylyl cyclase in cells expressing the recombinant gonadotropin receptors. Endocrinology 132:1007-1016
    • (1993) Endocrinology , vol.132 , pp. 1007-1016
    • Sanchez-Yague, J.1    Hipkin, R.W.2    Ascoli, M.3
  • 20
  • 22
    • 0029666283 scopus 로고    scopus 로고
    • Involvement of Gs and Gi Proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C
    • Herrlich A, Kuhn B, Grosse R, Schmid A, Schultz G, Gudermann T 1996 Involvement of Gs and Gi Proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C. J Biol Chem 271:16764-16772
    • (1996) J Biol Chem , vol.271 , pp. 16764-16772
    • Herrlich, A.1    Kuhn, B.2    Grosse, R.3    Schmid, A.4    Schultz, G.5    Gudermann, T.6
  • 23
    • 0026446569 scopus 로고
    • Carbohydrate moiety of follitropin receptor is not required for high affinity hormone-binding or for functional coupling between receptor and guanine nucleotide-binding protein in bovine calf testis membranes
    • Dattatreyamurty B, Reichert Jr LE 1992 Carbohydrate moiety of follitropin receptor is not required for high affinity hormone-binding or for functional coupling between receptor and guanine nucleotide-binding protein in bovine calf testis membranes. Endocrinology 131:2437-2445
    • (1992) Endocrinology , vol.131 , pp. 2437-2445
    • Dattatreyamurty, B.1    Reichert Jr., L.E.2
  • 24
    • 0025333016 scopus 로고
    • N-linked oligosaccharides are not required for hormone binding of the lutropin receptor in a Leydig tumor cell line and rat granulosa cells
    • Ji I, Slaughter RG, Ji TH 1990 N-linked oligosaccharides are not required for hormone binding of the lutropin receptor in a Leydig tumor cell line and rat granulosa cells. Endocrinology 127:494-406
    • (1990) Endocrinology , vol.127 , pp. 494-1406
    • Ji, I.1    Slaughter, R.G.2    Ji, T.H.3
  • 25
    • 0000518608 scopus 로고
    • Deglycosylation of the human luteinizing hormone receptor does not affect ligand binding and signal transduction
    • Tapanainen JS, Bo M, Dunkel L, Billig H, Perlas EA, Boime I, Hsueh AJW 1993 Deglycosylation of the human luteinizing hormone receptor does not affect ligand binding and signal transduction. Endocrine J 1:219-225
    • (1993) Endocrine J , vol.1 , pp. 219-225
    • Tapanainen, J.S.1    Bo, M.2    Dunkel, L.3    Billig, H.4    Perlas, E.A.5    Boime, I.6    Hsueh, A.J.W.7
  • 26
    • 0024207479 scopus 로고
    • Effect of deglycosylation on the structure and hormone-binding activity of the lutropin receptor
    • Keinanen KP 1988 Effect of deglycosylation on the structure and hormone-binding activity of the lutropin receptor. Biochem J 256:719-724
    • (1988) Biochem J , vol.256 , pp. 719-724
    • Keinanen, K.P.1
  • 27
    • 0025877404 scopus 로고
    • Significance of the glycan moiety of the rat ovarian luteinizing hormone/chorionic gonadotropin (CG) receptor and human CG for receptor-hormone interaction
    • Petaja-Repo UE, Merz WE, Rajaniemi HJ 1991 Significance of the glycan moiety of the rat ovarian luteinizing hormone/chorionic gonadotropin (CG) receptor and human CG for receptor-hormone interaction. Endocrinology 128:1209-1217
    • (1991) Endocrinology , vol.128 , pp. 1209-1217
    • Petaja-Repo, U.E.1    Merz, W.E.2    Rajaniemi, H.J.3
  • 28
    • 0029094166 scopus 로고
    • Functional glycosylation sites of the rat luteinizing hormone receptor required for ligand binding
    • Zhang R, Cai H, Fatima N, Buczko E, Dufau ML 1995 Functional glycosylation sites of the rat luteinizing hormone receptor required for ligand binding. J Biol Chem 270:21722-21728
    • (1995) J Biol Chem , vol.270 , pp. 21722-21728
    • Zhang, R.1    Cai, H.2    Fatima, N.3    Buczko, E.4    Dufau, M.L.5
  • 29
    • 0024512863 scopus 로고
    • Phosphorylation and glycosylation of the luteinizing hormone receptor
    • Minegishi T, Delgado C, Dufau ML 1989 Phosphorylation and glycosylation of the luteinizing hormone receptor. Proc Natl Acad Sci USA 86:1470-1474
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1470-1474
    • Minegishi, T.1    Delgado, C.2    Dufau, M.L.3
  • 31
    • 0022003140 scopus 로고
    • Deglycosylation of asparagine-linked glycans by peptide: N-GlycosidaseF
    • Tarentino AL, Gomez CM, Plummer TH 1985 Deglycosylation of asparagine-linked glycans by peptide: N-GlycosidaseF. Biochemistry 24:4665-4671
    • (1985) Biochemistry , vol.24 , pp. 4665-4671
    • Tarentino, A.L.1    Gomez, C.M.2    Plummer, T.H.3
  • 32
    • 0025002788 scopus 로고
    • The orientation of the LH/CG receptor in rat luteal cells as revealed by site-specific antibodies
    • Rodriguez MC, Segaloff DL 1990 The orientation of the LH/CG receptor in rat luteal cells as revealed by site-specific antibodies. Endocrinology 127:674-681
    • (1990) Endocrinology , vol.127 , pp. 674-681
    • Rodriguez, M.C.1    Segaloff, D.L.2
  • 34
    • 0027093726 scopus 로고
    • Identification and characterization of an LH/CG receptor precursor in a human kidney cell line stably transfected with the rat luteal LH/CG receptor cDNA
    • Hipkin RW, Sanchez-Yague J, Ascoli M 1993 Identification and characterization of an LH/CG receptor precursor in a human kidney cell line stably transfected with the rat luteal LH/CG receptor cDNA. Mol Endocrinol 6:2210-2218
    • (1993) Mol Endocrinol , vol.6 , pp. 2210-2218
    • Hipkin, R.W.1    Sanchez-Yague, J.2    Ascoli, M.3
  • 35
    • 0020394235 scopus 로고
    • A new method for partial peptide mapping using N-chlorosuccinimide/urea and peptide silver staining in sodium dodecyl sulfate-polyacrylamide gels
    • Lischwe MA, Ochs D 1982 A new method for partial peptide mapping using N-chlorosuccinimide/urea and peptide silver staining in sodium dodecyl sulfate-polyacrylamide gels. Anal Biochem 127:453-457
    • (1982) Anal Biochem , vol.127 , pp. 453-457
    • Lischwe, M.A.1    Ochs, D.2
  • 36
    • 0021891884 scopus 로고
    • Assembly of asparagine-linked oligosaccharides
    • Kornfeld R, Kornfeld S 1985 Assembly of asparagine-linked oligosaccharides. Annu Rev Biochem 54: 631-664
    • (1985) Annu Rev Biochem , vol.54 , pp. 631-664
    • Kornfeld, R.1    Kornfeld, S.2
  • 37
    • 0019579733 scopus 로고
    • The role of the hydroxy amino acid in the triplet sequence Asn-Xaa-Thr(Ser) for the N-glycosylation step during glycoprotein biosynthesis
    • Bause E, Legler G 1981 The role of the hydroxy amino acid in the triplet sequence Asn-Xaa-Thr(Ser) for the N-glycosylation step during glycoprotein biosynthesis. Biochem J 195:639-644
    • (1981) Biochem J , vol.195 , pp. 639-644
    • Bause, E.1    Legler, G.2
  • 38
    • 0023941649 scopus 로고
    • The role of the asparagine-linked oligosaccharides of the a subunit in the secretion and assembly of human chorionic gonadotropin
    • Matzuk MM, Boime I 1988 The role of the asparagine-linked oligosaccharides of the a subunit in the secretion and assembly of human chorionic gonadotropin. J Cell Biol 106:1049-1-69
    • (1988) J Cell Biol , vol.106 , pp. 1049-1169
    • Matzuk, M.M.1    Boime, I.2
  • 39
    • 0019321485 scopus 로고
    • Inhibition of asparagine-linked glycosylation by incorporation of a threonine analog into nascent peptide chains
    • Hortin G, Boime I 1980 Inhibition of asparagine-linked glycosylation by incorporation of a threonine analog into nascent peptide chains. J Biol Chem 255:8007-8010
    • (1980) J Biol Chem , vol.255 , pp. 8007-8010
    • Hortin, G.1    Boime, I.2
  • 40
    • 0026344397 scopus 로고
    • Changes in binding activity of luteinizing hormone receptors by site directed mutagenesis of potential glycosylation sites
    • Zhang R, Tsai-Morris CH, Kitamura M, Buczko E, Dufau ML 1991 Changes in binding activity of luteinizing hormone receptors by site directed mutagenesis of potential glycosylation sites. Biochem Biophys Res Commun 181:804-808
    • (1991) Biochem Biophys Res Commun , vol.181 , pp. 804-808
    • Zhang, R.1    Tsai-Morris, C.H.2    Kitamura, M.3    Buczko, E.4    Dufau, M.L.5
  • 41
    • 0027434258 scopus 로고
    • Disruption of potential sites for N-linked glycosylation does not impair hormone binding to the lutropin/choriogonadotropin receptor if Asn 173 is left intact
    • Liu X, Davis D, Segaloff DL 1993 Disruption of potential sites for N-linked glycosylation does not impair hormone binding to the lutropin/choriogonadotropin receptor if Asn 173 is left intact. J Biol Chem 268:1513-1516
    • (1993) J Biol Chem , vol.268 , pp. 1513-1516
    • Liu, X.1    Davis, D.2    Segaloff, D.L.3
  • 42
    • 0026778801 scopus 로고
    • Truncation of the cytoplasmic tail of the lutropin/ choriogonadotropin receptor prevents agonist-induced uncoupling
    • Sanchez-Yague J, Rodriguez MC, Segaloff DL, Ascoli M 1992 Truncation of the cytoplasmic tail of the lutropin/ choriogonadotropin receptor prevents agonist-induced uncoupling. J Biol Chem 267:7217-7220
    • (1992) J Biol Chem , vol.267 , pp. 7217-7220
    • Sanchez-Yague, J.1    Rodriguez, M.C.2    Segaloff, D.L.3    Ascoli, M.4
  • 43
    • 0018721020 scopus 로고
    • Biological activities of the two major components of tunicamycin
    • Mahoney WC, Duksin D 1979 Biological activities of the two major components of tunicamycin. J Biol Chem 254:6572-6576
    • (1979) J Biol Chem , vol.254 , pp. 6572-6576
    • Mahoney, W.C.1    Duksin, D.2
  • 44
    • 0030043737 scopus 로고    scopus 로고
    • Deletions of portions of the extracellular loops of the lutropin/choriogonadotropin receptor decrease the binding affinity for oLH, but not hCG, by preventing the formation of mature cell surface receptor
    • Abell A, Liu X, Segaloff DL 1996 Deletions of portions of the extracellular loops of the lutropin/choriogonadotropin receptor decrease the binding affinity for oLH, but not hCG, by preventing the formation of mature cell surface receptor. J Biol Chem 271:4518-4527
    • (1996) J Biol Chem , vol.271 , pp. 4518-4527
    • Abell, A.1    Liu, X.2    Segaloff, D.L.3
  • 45
    • 0024379308 scopus 로고
    • A single amino acid substitution eliminates the stringent carbohydrate requirement for intracellular transport of a viral glycoprotein
    • Pitta AM, Rose JK, Machamer CE 1989 A single amino acid substitution eliminates the stringent carbohydrate requirement for intracellular transport of a viral glycoprotein. J Virol 63:3801-3809
    • (1989) J Virol , vol.63 , pp. 3801-3809
    • Pitta, A.M.1    Rose, J.K.2    Machamer, C.E.3
  • 46
    • 0028241866 scopus 로고
    • Post-translational requirements for functional factor V and factor VIII secretion in mammalian cells
    • Pittman DD, Tomkinson KN, Kaufman RJ 1994 Post-translational requirements for functional factor V and factor VIII secretion in mammalian cells. J Biol Chem 269:17329-17337
    • (1994) J Biol Chem , vol.269 , pp. 17329-17337
    • Pittman, D.D.1    Tomkinson, K.N.2    Kaufman, R.J.3
  • 47
    • 0028842897 scopus 로고
    • Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not the lutropin/choriogonadotropin receptor
    • Rozell TG, Wang H, Liu X, Segaloff DL 1995 Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not the lutropin/choriogonadotropin receptor. Mol Endocrinol 9:1727-1736
    • (1995) Mol Endocrinol , vol.9 , pp. 1727-1736
    • Rozell, T.G.1    Wang, H.2    Liu, X.3    Segaloff, D.L.4
  • 48
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR 1989 Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 49
    • 0024556150 scopus 로고
    • Engineering hybrid genes without the use of restriction enzymes: Gene splicing by overlap extension
    • Horton RM, Hunt HD, Ho SN, Pullen JK, Pease LR 1989 Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene 77:61-68
    • (1989) Gene , vol.77 , pp. 61-68
    • Horton, R.M.1    Hunt, H.D.2    Ho, S.N.3    Pullen, J.K.4    Pease, L.R.5
  • 51
    • 0022362533 scopus 로고
    • A simple and rapid method using polyethylenemine-treated filters for assay of solubilized LH/hCG receptors
    • Roche PC, Bergert ER, Ryan RJ 1985 A simple and rapid method using polyethylenemine-treated filters for assay of solubilized LH/hCG receptors. Endocrinology 117:790-792
    • (1985) Endocrinology , vol.117 , pp. 790-792
    • Roche, P.C.1    Bergert, E.R.2    Ryan, R.J.3
  • 52
    • 0019061918 scopus 로고
    • LIGAND: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ, Rodbard D 1980 LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220-239
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 53
    • 0026591515 scopus 로고
    • Effects of truncations of the cytoplasmic tail of the luteinizing hormone/chorionic gonadotropin receptor on receptor-mediated hormone internalization
    • Rodriguez MC, Xie Y-B, Wang H, Collison K, Segaloff DL 1992 Effects of truncations of the cytoplasmic tail of the luteinizing hormone/chorionic gonadotropin receptor on receptor-mediated hormone internalization. Mol Endocrinol 6:327-336
    • (1992) Mol Endocrinol , vol.6 , pp. 327-336
    • Rodriguez, M.C.1    Xie, Y.-B.2    Wang, H.3    Collison, K.4    Segaloff, D.L.5
  • 54
    • 0343053231 scopus 로고
    • Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells
    • Ascoli M, Puett D 1978 Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells. Proc Natl Acad Sci USA 75:99-102
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 99-102
    • Ascoli, M.1    Puett, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.