메뉴 건너뛰기




Volumn 67, Issue 6, 2005, Pages 2196-2209

Triglyceride accumulation in injured renal tubular cells: Alterations in both synthetic and catabolic pathways

Author keywords

Endotoxemia; Rhabdomyolysis; Triacylglycerol

Indexed keywords

ACYL COENZYME A; ANTIMYCIN A1; CARRIER PROTEIN; DIACYLGLYCEROL ACYLTRANSFERASE; FATTY ACID SYNTHASE; FATTY ACID TRANSPORTER; GLYCEROL; PHOSPHOLIPASE A2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ACYLTRANSFERASE; DGAT1 PROTEIN, MOUSE; DGAT2 PROTEIN, HUMAN; FATTY ACID; LACTATE DEHYDROGENASE; MESSENGER RNA; PHOSPHOLIPASE A; SLC27A4 PROTEIN, MOUSE; TRIACYLGLYCEROL LIPASE;

EID: 23044471901     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2005.00325.x     Document Type: Article
Times cited : (66)

References (36)
  • 1
    • 0036429189 scopus 로고    scopus 로고
    • Concerted elevation of acyl-coenzyme A: Diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin
    • MEEGALLA RL, BILLHEIMER JT, CHENG D: Concerted elevation of acyl-coenzyme A: diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin. Biochem Biophys Res Commun 298:317-323, 2002
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 317-323
    • Meegalla, R.L.1    Billheimer, J.T.2    Cheng, D.3
  • 2
    • 0023085357 scopus 로고
    • From dietary glucose to liver glycogen: The full circle round
    • McGARRY JD, KUWAJIMA M, NEWGARD CB, et al: From dietary glucose to liver glycogen: The full circle round. Annu Rev Nutr 7:51-73, 1987
    • (1987) Annu Rev Nutr , vol.7 , pp. 51-73
    • McGarry, J.D.1    Kuwajima, M.2    Newgard, C.B.3
  • 3
    • 0037205492 scopus 로고    scopus 로고
    • Disruption of mitochondrial beta-Oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse
    • JANSSEN U, STOFFEL W: Disruption of mitochondrial beta-Oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse. J Biol Chem 277:19579-19584, 2002
    • (2002) J Biol Chem , vol.277 , pp. 19579-19584
    • Janssen, U.1    Stoffel, W.2
  • 4
    • 0037453056 scopus 로고    scopus 로고
    • Triglyceride accumulation protects against fatty acid-induced lipotoxicity
    • LISTENBERGER LL, HAN X, LEWIS SE, et al: Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci USA 100:3077-3082, 2003
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3077-3082
    • Listenberger, L.L.1    Han, X.2    Lewis, S.E.3
  • 5
    • 0038509036 scopus 로고    scopus 로고
    • Lipotoxicity: When tissue overeat
    • SCHAEFFER JE: Lipotoxicity: When tissue overeat. Curr Opin Lipidology 14:281-287, 2003
    • (2003) Curr Opin Lipidology , vol.14 , pp. 281-287
    • Schaeffer, J.E.1
  • 6
    • 3042824524 scopus 로고    scopus 로고
    • Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
    • FELDSTEIN AE, WERNEBURG NW, CANBAY A, et al: Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology 40:185-194, 2004
    • (2004) Hepatology , vol.40 , pp. 185-194
    • Feldstein, A.E.1    Werneburg, N.W.2    Canbay, A.3
  • 7
    • 0021227520 scopus 로고
    • Lipid alterations induced by renal ischemia: Pathogenic factor in membrane damage
    • MATTHYS E, PATEL Y, KREISBERG J, et al: Lipid alterations induced by renal ischemia: Pathogenic factor in membrane damage. Kidney Int 26:153-161, 1984
    • (1984) Kidney Int , vol.26 , pp. 153-161
    • Matthys, E.1    Patel, Y.2    Kreisberg, J.3
  • 8
    • 0030842898 scopus 로고    scopus 로고
    • Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure
    • ZAGER RA, IWATA M, CONRAD DS, et al: Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure. Kidney Int 52:60-70, 1997
    • (1997) Kidney Int , vol.52 , pp. 60-70
    • Zager, R.A.1    Iwata, M.2    Conrad, D.S.3
  • 9
    • 0030299860 scopus 로고    scopus 로고
    • 2: A potentially important determinant of adenosine triphosphate levels during hypoxic-reoxygenation tubular injury
    • 2: A potentially important determinant of adenosine triphosphate levels during hypoxic-reoxygenation tubular injury. J Am Soc Nephrol 7:2327-2339, 1996
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2327-2339
    • Zager, R.A.1    Conrad, D.S.2    Burkhart, K.3
  • 10
    • 13144281703 scopus 로고    scopus 로고
    • Identification of a gene encoding an acyl CoA: Diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
    • CASES S, SMITH SJ, ZHENG YW, et al: Identification of a gene encoding an acyl CoA: diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis. Proc Nat Acad Sci USA 95:13018-13023, 1998
    • (1998) Proc Nat Acad Sci USA , vol.95 , pp. 13018-13023
    • Cases, S.1    Smith, S.J.2    Zheng, Y.W.3
  • 12
    • 0020806216 scopus 로고
    • Effect of unilateral ureteral obstruction on metabolism of renal lipids in the rat
    • TANNENBAUM J, PURKERSON ML, KLAHR S: Effect of unilateral ureteral obstruction on metabolism of renal lipids in the rat. Am J Physiol 245:F254-F262, 1983
    • (1983) Am J Physiol , vol.245
    • Tannenbaum, J.1    Purkerson, M.L.2    Klahr, S.3
  • 13
    • 85030732481 scopus 로고    scopus 로고
    • Renal tubular triglyceride accumulation following endotoxic, toxic, and ischemic injury
    • in press
    • ZAGER RA, JOHNSON ACM, HANSON SY: Renal tubular triglyceride accumulation following endotoxic, toxic, and ischemic injury. Kidney Int (in press)
    • Kidney Int
    • Zager, R.A.1    Johnson, A.C.M.2    Hanson, S.Y.3
  • 14
    • 77956857784 scopus 로고
    • Metabolism of triacylglycerols
    • edited by Vance DE, Vance JE, Amsterdam, Elsevier
    • BRINDLEY DN: Metabolism of triacylglycerols, in Biochemistry of Lipids, Lipoproteins, and Membranes, edited by Vance DE, Vance JE, Amsterdam, Elsevier 1991, pp 171-203
    • (1991) Biochemistry of Lipids, Lipoproteins, and Membranes , pp. 171-203
    • Brindley, D.N.1
  • 15
    • 0030175841 scopus 로고    scopus 로고
    • Biosynthesis of triacylglycerols
    • LEHNER R, KUKSIS A: Biosynthesis of triacylglycerols. Prog Lipid Res 35:169-201, 1996
    • (1996) Prog Lipid Res , vol.35 , pp. 169-201
    • Lehner, R.1    Kuksis, A.2
  • 16
    • 0034128280 scopus 로고    scopus 로고
    • Triglyceride synthesis: Insights from the cloning of diacylglyerol acyltransferase
    • FARESE RV JR., CASES S, SMITH SJ: Triglyceride synthesis: Insights from the cloning of diacylglyerol acyltransferase. Curr Opin Lipidol 11:229-234, 2000
    • (2000) Curr Opin Lipidol , vol.11 , pp. 229-234
    • Farese Jr., R.V.1    Cases, S.2    Smith, S.J.3
  • 17
    • 0028010818 scopus 로고
    • HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney
    • RYAN MJ, JOHNSON G, KIRK J, et al: HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int 45:48-57, 1994
    • (1994) Kidney Int , vol.45 , pp. 48-57
    • Ryan, M.J.1    Johnson, G.2    Kirk, J.3
  • 18
    • 0037222320 scopus 로고    scopus 로고
    • Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression
    • JOHNSON AC, YABU JM, HANSON S, et al: Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression. Am J Pathol 162:283-291, 2003
    • (2003) Am J Pathol , vol.162 , pp. 283-291
    • Johnson, A.C.1    Yabu, J.M.2    Hanson, S.3
  • 19
    • 0036966284 scopus 로고    scopus 로고
    • The mevalonate pathway during acute tubular injury: Selected determinants and consequences
    • ZAGER RA, SHAH VO, SHAH HV, et al: The mevalonate pathway during acute tubular injury: Selected determinants and consequences. Am J Pathol 161:681-692, 2002
    • (2002) Am J Pathol , vol.161 , pp. 681-692
    • Zager, R.A.1    Shah, V.O.2    Shah, H.V.3
  • 20
    • 0023158563 scopus 로고
    • Inorganic and organic phosphate measurements in the nanomolar range
    • VAN VELDHOVEN PP, MANNAERTS GP: Inorganic and organic phosphate measurements in the nanomolar range. Anal Biochem 161:45-48, 1987
    • (1987) Anal Biochem , vol.161 , pp. 45-48
    • Van Veldhoven, P.P.1    Mannaerts, G.P.2
  • 21
    • 3242685815 scopus 로고    scopus 로고
    • Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells
    • MENENDEZ JA, VELLON L, MEHMI I, et al: Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. Proc Natl Acad of Sci USA 101:10715-10720, 2004
    • (2004) Proc Natl Acad of Sci USA , vol.101 , pp. 10715-10720
    • Menendez, J.A.1    Vellon, L.2    Mehmi, I.3
  • 22
    • 1542319755 scopus 로고    scopus 로고
    • Identification and molecular characterization of the beta-ketoacyl-[acyl carrier protein] synthase component of the Arabidopsis mitochondrial fatty acid synthase
    • YASUNO R, VON WETTSTEIN-KNOWLES P, WADA H: Identification and molecular characterization of the beta-ketoacyl-[acyl carrier protein] synthase component of the Arabidopsis mitochondrial fatty acid synthase. J Biol Chem 279:8242-8251, 2004
    • (2004) J Biol Chem , vol.279 , pp. 8242-8251
    • Yasuno, R.1    Von Wettstein-Knowles, P.2    Wada, H.3
  • 23
    • 0030940841 scopus 로고    scopus 로고
    • Animal fatty acid synthase: Functional mapping and cloning and expression of the domain I constituent activities
    • CHIRALA SS, HUANG WY, JAYAKUMAR A, et al: Animal fatty acid synthase: Functional mapping and cloning and expression of the domain I constituent activities. Proc Natl Acad Sci USA 94:5588-5593, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5588-5593
    • Chirala, S.S.1    Huang, W.Y.2    Jayakumar, A.3
  • 24
    • 0029051666 scopus 로고
    • Human fatty acid synthase: Properties and molecular cloning
    • JAYAKUMAR A, TAI MH, HUANG WY, et al: Human fatty acid synthase: Properties and molecular cloning. Proc Natl Acad Sci USA 92:8695-8699, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8695-8699
    • Jayakumar, A.1    Tai, M.H.2    Huang, W.Y.3
  • 26
    • 1242317654 scopus 로고    scopus 로고
    • A current review of fatty acid transport proteins (SLC27)
    • STAHL A: A current review of fatty acid transport proteins (SLC27). Pflugers Archiv Eur J Physiol 447:722-727, 2004
    • (2004) Pflugers Archiv Eur J Physiol , vol.447 , pp. 722-727
    • Stahl, A.1
  • 28
    • 0032739599 scopus 로고    scopus 로고
    • Renal cortical ceramide patterns during ischemic and toxic injury: Assessments by HPLC-mass spectrometry
    • KALHORN T, ZAGER RA: Renal cortical ceramide patterns during ischemic and toxic injury: Assessments by HPLC-mass spectrometry. Am J Physiol 277:F723-733, 1999
    • (1999) Am J Physiol , vol.277
    • Kalhorn, T.1    Zager, R.A.2
  • 29
    • 0022343383 scopus 로고
    • Effects of mannitol on the postischemic kidney: Biochemical, functional, and morphologic assessments
    • ZAGER RA, MAHAN J, MEROLA AJ: Effects of mannitol on the postischemic kidney: Biochemical, functional, and morphologic assessments. Lab Invest 53:433-442, 1985
    • (1985) Lab Invest , vol.53 , pp. 433-442
    • Zager, R.A.1    Mahan, J.2    Merola, A.J.3
  • 30
    • 0031888839 scopus 로고    scopus 로고
    • Intracellular targets in heme protein-induced renal injury
    • NATH KA, GRANDE JP, CROATT AJ, et al: Intracellular targets in heme protein-induced renal injury. Kidney Int 53:100-111, 1998
    • (1998) Kidney Int , vol.53 , pp. 100-111
    • Nath, K.A.1    Grande, J.P.2    Croatt, A.J.3
  • 31
    • 1642294981 scopus 로고    scopus 로고
    • Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules
    • FELDKAMP T, KRIBBEN A, ROESER NF, et al: Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules. Am J Physiol 286:F749-F759, 2004
    • (2004) Am J Physiol , vol.286
    • Feldkamp, T.1    Kribben, A.2    Roeser, N.F.3
  • 32
    • 0031748928 scopus 로고    scopus 로고
    • 2 and myoglobin-induced proximal tubular cell attack
    • 2 and myoglobin-induced proximal tubular cell attack. Kidney Int 53:1661-1672, 1998
    • (1998) Kidney Int , vol.53 , pp. 1661-1672
    • Zager, R.A.1    Burkhart, K.M.2
  • 33
    • 0029047757 scopus 로고
    • Protein synthesis inhibition induces cytoresistance in cultured human proximal tubular (HK-2) cells
    • IWATA M, HERRINGTON J, ZAGER RA: Protein synthesis inhibition induces cytoresistance in cultured human proximal tubular (HK-2) cells. Am J Physiol 268:F1154-F1163, 1995
    • (1995) Am J Physiol , vol.268
    • Iwata, M.1    Herrington, J.2    Zager, R.A.3
  • 34
    • 0023605596 scopus 로고
    • Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules
    • WEINBERG JM, DAVIS JA, ABARZUA M, RAJAN T: Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules. J Clin Invest 80:1446-1454, 1987
    • (1987) J Clin Invest , vol.80 , pp. 1446-1454
    • Weinberg, J.M.1    Davis, J.A.2    Abarzua, M.3    Rajan, T.4
  • 35
    • 0029661827 scopus 로고    scopus 로고
    • 2-induced cytoprotection of proximal tubules: Potential determinants and specificity for ATP depletion-mediated injury
    • 2-induced cytoprotection of proximal tubules: potential determinants and specificity for ATP depletion-mediated injury. J Am Soc Nephrol 7:64-72, 1996
    • (1996) J Am Soc Nephrol , vol.7 , pp. 64-72
    • Zager, R.A.1    Burkhart, K.M.2    Conrad, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.