Effect of DNA polymerase β loop variants on discrimination of O 6-methyldeoxyguanosine modification present in the nucleotide versus template substrate

Biochemistry

Volumn 44, Issue 30, 2005, Pages 10378-10387

  Hamid, Subarna ^a   Eckert, Kristin A ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINO ACIDS; BIOASSAY; BIOCHEMISTRY; ENZYMES; SUBSTRATES; SYNTHESIS (CHEMICAL);

ANTIMUTATOR TENDENCY; BIOCHEMICAL ASSAYS; DNA POLYMERASE; TEMPLATE TRANSLESION SYNTHESIS;

DNA;

3' AZIDO 3' DEOXYTHYMIDINE TRIPHOSPHATE; 6 O METHYLDEOXYGUANOSINE; DEOXYGUANOSINE DERIVATIVE; DEOXYGUANOSINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA; METHYLNITROSOUREA; NUCLEOTIDE; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL ANALYSIS; DNA TEMPLATE; EXCISION REPAIR; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN VARIANT; STEADY STATE; SYNTHESIS; WILD TYPE;

ALKYLATING AGENTS; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; BASE SEQUENCE; DEOXYCYTOSINE NUCLEOTIDES; DEOXYGUANOSINE; DNA DAMAGE; DNA POLYMERASE BETA; DNA PRIMERS; GLUTAMIC ACID; LYSINE; METHIONINE; METHYLNITROSOUREA; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RATS; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC; THYMINE NUCLEOTIDES;

EID: 23044445843     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047444i     Document Type: Article

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