Hydrophobic interactions in the hinge domain of DNA polymerase β are important but not sufficient for maintaining fidelity of DNA synthesis

Biochemistry

Volumn 39, Issue 37, 2000, Pages 11399-11407

  Opresko, Patricia L ^a,b   Shiman, Ross ^c   Eckert, Kristin A ^a  

^a PENN STATE CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA DIRECTED DNA POLYMERASE BETA;

ARTICLE; CATALYSIS; DNA SYNTHESIS; ENZYME PURIFICATION; ENZYME STRUCTURE; GENE MUTATION; HYDROPHOBICITY; KINETICS; NONHUMAN; PRIORITY JOURNAL; STEADY STATE;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CATALYSIS; DNA MUTATIONAL ANALYSIS; DNA POLYMERASE BETA; DNA PRIMERS; DNA REPLICATION; FRAMESHIFT MUTATION; KINETICS; LEUCINE; MOLECULAR SEQUENCE DATA; PHENYLALANINE; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE DELETION; SIMPLEXVIRUS; THYMIDINE KINASE; TRYPTOPHAN; TYROSINE; VIRAL PROTEINS;

EID: 0034687093     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000698t     Document Type: Article

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