Gender differences in genetic damage induced by the tobacco-specific nitrosamine NNK and the influence of the Thr241Met polymorphism in the XRCC3 gene

Environmental and Molecular Mutagenesis

Volumn 46, Issue 1, 2005, Pages 22-29

  Hill, Courtney E ^a   Affatato, Alessandra A ^a   Wolfe, Kevin J ^a   Lopez, Mirtha S ^a   Hallberg, Csilla K ^a   Canistro, Donatella ^a   Abdel Rahman, Sherif Z ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

DNA repair; Mutagen sensitivity; NNK; Polymorphism; Smoking; XRCC3

Indexed keywords

CARCINOGEN; METHIONINE; NITROSAMINE; NITROSAMINE 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; THREONINE; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; ASSAY; CANCER MORTALITY; CANCER RISK; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FEMALE; GENDER; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTOXICITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; LUNG ADENOCARCINOMA; MALE; MUTAGEN SENSITIVITY ASSAY; PERIPHERAL LYMPHOCYTE; SMOKING; TOBACCO; XRCC3 GENE;

ADULT; AMINO ACID SUBSTITUTION; CELLS, CULTURED; CHROMOSOME ABERRATIONS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; GENE FREQUENCY; GENOTYPE; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; MUTAGENS; NITROSAMINES; POLYMORPHISM, GENETIC; SEX FACTORS; SMOKING; TOBACCO;

NICOTIANA TABACUM;

EID: 22944460624     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20128     Document Type: Article

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