Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats

Life Sciences

Volumn 65, Issue 2, 1999, Pages PL27-PL32

  Matsuda, Hisashi ^a   Li, Yuhao ^a   Yoshikawa, Masayuki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Capsaicin sensitive sensory nerve; Ethanol induced gastrio lesion; Momordin Ic; Nitric oxide; Prostaglandin; Sulfhydryl

Indexed keywords

ALCOHOL; CAPSAICIN; INDOMETACIN; MOMORDIN; N ETHYLMALEIMIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG INDUCED DISEASE; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; FRUIT; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SENSORY NERVE; STOMACH MUCOSA LESION; STOMACH PROTECTION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA; BASSIA SCOPARIA; KOCHIA; SCOPARIA;

EID: 0033522839     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0024-3205(99)00241-6     Document Type: Article

References (21)

1. H. Matsuda, Y. LI, T. Murakami, J. Yamahara, and M. Yoshikawa, Bioorg. Med. Chem. 7 (1999), in press.
2. H. Matsuda, Y. LI, T. Murakami, N. Matsumura, J. Yamahara, and M. Yoshikawa, Chem. Pharm. Bull. 46, 1399-1403 (1998).
3. H. Matsuda, Y. Li, T. Murakami, J. Yamahara, and M. Yoshikawa, Life Sci. 63, PL245-250 (1998).
4. D. Salvemini, S.L. Settle, J.L. Masferrer, K. Seibert, M.G. Currie, and P. Needleman, Br. J. Pharmacol. 114, 1171-1178 (1995).
5. B.J.R. Whittle, J. Lopez-Belmomte, and S. Moncada, Br. J. Pharmacol. 99, 607-611 (1990).
6. I. Szelenyi and K. Brune, Dig. Dis. Sci. 31, 1207-1210 (1986).
7. M. Yoshikawa, H. Shimada, T. Morikawa, S. Yoshizumi, N. Matsumura, T. Murakami, H. Matsuda, K. Hori, and J. Yamahara, Chem. Pharm. Bull. 45, 1300-1305 (1997).
8. M.D. Barrachina, V. Martínez, L. Wang, J.Y. Wei, Y. Taché, Proc. Natl. Acad. Sci. USA, 94, 10455-10460 (1997).
9. P. Holzer and W. Sametz, Gastroenterology 91, 975-981 (1986).
10. P. Holzer, Neuroscience 24, 739-768 (1988).
11. A. Robert, Gastroenterology 77, 761-767 (1979).
12. T.K. Chaudhury and A. Robert, Dig. Dis. Sci. 25, 830-836 (1980).
13. J.F. Brown, A.C. Keates, P.J. Hanson, and B.J.R. Whittle, Am. J. Physiol. 265, G418-G422 (1993).
14. B.J.R. Whittle and J. Lopez-Belmomte, J. Physiol. Pharmacol. 44, 91-107 (1993).
15. L. Sautebin, A. Ialenti, A. Ianaro, and M. Di Rosa, Br. J. Pharmacol. 114, 323-328 (1995).
16. M. Di Rosa, A. Ialenti, A. Ianaro, L. Sautebin, Prostaglandins Leukot. Essent. Fatty Acids 54, 229-238 (1996).
17. B.M. Peskar, M. Respondek, K.M. Müller, and B.A. Peskar, Eur. J. Pharmacol. 198, 113-114 (1991).
18. S. Szabo, J.S. Trier, and P.W. Frankel, Science 214, 200-202 (1981).
19. N. Lambrecht, M. Burchert, M. Respondek, K.M. Müller, and B.M. Peskar, Gastroenterology 104, 1371-1380 (1993).
20. N. Lambrecht, M. Trautmann, R. Korolkiewicz, M. Liszkay, and B.M. Peskar, Gut 34, 329-337 (1993).
21. D. LI, H.E. Raybould, E. Quintero, and P.H. Guth, Am. J. Physiol. 261, G657-G661 (1991).