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Volumn 16, Issue 4, 2005, Pages 1038-1044

Oligonucleotides conjugated to short lysine chains

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DICHROISM; ESTERS; MASS SPECTROMETRY; NANOCATALYSTS; PEPTIDES; SYNTHESIS (CHEMICAL);

EID: 22644446801     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc049729d     Document Type: Article
Times cited : (17)

References (64)
  • 1
    • 0041582974 scopus 로고
    • Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
    • Zamecnik, P. C., and Stephenson, M. L. (1978) Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. U.S.A. 75, 280-284.
    • (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 280-284
    • Zamecnik, P.C.1    Stephenson, M.L.2
  • 2
    • 0034722899 scopus 로고    scopus 로고
    • Potential roles of antisense technology in cancer chemotherapy
    • Crooke, S. T. (2000) Potential roles of antisense technology in cancer chemotherapy. Oncogene 19, 6651-6659.
    • (2000) Oncogene , vol.19 , pp. 6651-6659
    • Crooke, S.T.1
  • 3
    • 0032700656 scopus 로고    scopus 로고
    • Molecular mechanisms of action of antisense drugs
    • Crooke, S. T. (1999) Molecular mechanisms of action of antisense drugs. Biochim. Biophys. Acta 1489, 31-44.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 31-44
    • Crooke, S.T.1
  • 4
    • 0037373763 scopus 로고    scopus 로고
    • Structural modifications of antisense oligonucleotides
    • Urban, E., and Noe, C. R. (2003) Structural modifications of antisense oligonucleotides. Farmaco. 58, 243-258.
    • (2003) Farmaco , vol.58 , pp. 243-258
    • Urban, E.1    Noe, C.R.2
  • 5
    • 0030727765 scopus 로고    scopus 로고
    • The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically modified DNA: RNA duplexes
    • Freier, S. M., and Altmann, K. H. (1997) The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically modified DNA: RNA duplexes. Nucleic Acids Res. 25, 4429-4443.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4429-4443
    • Freier, S.M.1    Altmann, K.H.2
  • 6
    • 0032697942 scopus 로고    scopus 로고
    • A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
    • Levin, A. A. (1999) A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim. Biophys. Acta 1489, 69-84.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 69-84
    • Levin, A.A.1
  • 7
    • 0034945407 scopus 로고    scopus 로고
    • Technology evaluation: Fomivirsen, Isis Pharmaceuticals Inc/CIBA vision
    • Orr, R. M. (2001) Technology evaluation: fomivirsen, Isis Pharmaceuticals Inc/CIBA vision. Curr. Opin. Mol. Ther. 3, 288-294.
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , pp. 288-294
    • Orr, R.M.1
  • 8
    • 0035845318 scopus 로고    scopus 로고
    • Antisense therapy in oncology: New hope for an old idea?
    • Tamm, I., Dorken, B., and Hartmann, G. (2001) Antisense therapy in oncology: new hope for an old idea? Lancet 358, 489-497.
    • (2001) Lancet , vol.358 , pp. 489-497
    • Tamm, I.1    Dorken, B.2    Hartmann, G.3
  • 10
    • 3543128235 scopus 로고    scopus 로고
    • Lessons learnt from Genasense's failure
    • Frantz, S. (2004) Lessons learnt from Genasense's failure. Nat Rev Drug Discovery 3, 542-543.
    • (2004) Nat Rev Drug Discovery , vol.3 , pp. 542-543
    • Frantz, S.1
  • 12
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams, J. M., and Cory, S. (1998) The Bcl-2 protein family: arbiters of cell survival. Science. 281, 1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 15
    • 0036850631 scopus 로고    scopus 로고
    • Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides
    • Dias, N., and Stein, C. A. (2002) Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides. Eur. J. Pharm. Biopharm. 54, 263-269.
    • (2002) Eur. J. Pharm. Biopharm. , vol.54 , pp. 263-269
    • Dias, N.1    Stein, C.A.2
  • 16
    • 2442478364 scopus 로고    scopus 로고
    • Antisense RNA down-regulation of bcl-2 expression in DU145 prostate cancer cells does not diminish the cytostatic effects of G3139 (Oblimersen)
    • Raffo, A., Lai, J. C., Stein, C. A., Miller, P., Scaringe, S., Khvorova, A., and Benimetskaya, L. (2004) Antisense RNA down-regulation of bcl-2 expression in DU145 prostate cancer cells does not diminish the cytostatic effects of G3139 (Oblimersen). Clin Cancer Res. 10, 3195-3206.
    • (2004) Clin Cancer Res. , vol.10 , pp. 3195-3206
    • Raffo, A.1    Lai, J.C.2    Stein, C.A.3    Miller, P.4    Scaringe, S.5    Khvorova, A.6    Benimetskaya, L.7
  • 17
    • 1042275580 scopus 로고    scopus 로고
    • G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner
    • Lai, J. C., Benimetskaya, L., Santella, R. M., Wang, Q., Miller, P. S., and Stein, C. A. (2003) G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner. Mol Cancer Ther. 2, 1031-1043.
    • (2003) Mol Cancer Ther. , vol.2 , pp. 1031-1043
    • Lai, J.C.1    Benimetskaya, L.2    Santella, R.M.3    Wang, Q.4    Miller, P.S.5    Stein, C.A.6
  • 18
    • 0032750621 scopus 로고    scopus 로고
    • 2′-carbohydrate modifications in antisense oligonucleotide therapy: Importance of conformation, configuration and conjugation
    • Manoharan, M. (1999) 2′-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation. Biochim. Biophys. Acta 1489, 117-130.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 117-130
    • Manoharan, M.1
  • 20
    • 0025825242 scopus 로고
    • 2′-O-methyl, 2′-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro UT snRNP-dependent mRNA processing event
    • Gotten, M., Oberhauser, B., Brunar, H., Holzner, A., Issakides, G., Noe, C. R., Schaffner, G., Wagner, E., and Birnstiel, M. L. (1991) 2′-O-methyl, 2′-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro UT snRNP-dependent mRNA processing event. Nucleic Acids Res. 19, 2629-2635.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 2629-2635
    • Gotten, M.1    Oberhauser, B.2    Brunar, H.3    Holzner, A.4    Issakides, G.5    Noe, C.R.6    Schaffner, G.7    Wagner, E.8    Birnstiel, M.L.9
  • 21
    • 0032103713 scopus 로고    scopus 로고
    • Investigations on the influence of 2′-O-alkyl modifications on the base pairing properties of oligonucleotides
    • Werner, D., Brunar, H., and Noe, C. R. (1998) Investigations on the influence of 2′-O-alkyl modifications on the base pairing properties of oligonucleotides. Pharm. Acta Helv. 73, 3-10.
    • (1998) Pharm. Acta Helv. , vol.73 , pp. 3-10
    • Werner, D.1    Brunar, H.2    Noe, C.R.3
  • 22
    • 0031019342 scopus 로고    scopus 로고
    • Binding affinity and specificity of Escherichia coli RNase H1: Impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids
    • Lima, W. F., and Crooke, S. T. (1997) Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids. Biochemistry. 36, 390-398.
    • (1997) Biochemistry , vol.36 , pp. 390-398
    • Lima, W.F.1    Crooke, S.T.2
  • 24
    • 0033588131 scopus 로고    scopus 로고
    • N-(Z-Cyanoethoxycarbonyloxy)succinimide: A New Reagent for Protection of Amino Groups in Oligoriucleotides
    • Manoharan, M., Prakash, T. P., Barber-Peortt, I., Bhat, B., Vasquez, G., Ross, B. S., and Cook P. D. (1999) N-(Z-Cyanoethoxycarbonyloxy)succinimide: A New Reagent for Protection of Amino Groups in Oligoriucleotides. J. Org. Chem. 64, 6468-6472.
    • (1999) J. Org. Chem. , vol.64 , pp. 6468-6472
    • Manoharan, M.1    Prakash, T.P.2    Barber-Peortt, I.3    Bhat, B.4    Vasquez, G.5    Ross, B.S.6    Cook, P.D.7
  • 25
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: The case for an RNase H-independent structural type
    • Summerton, J. (1999) Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim. Biophys. Acta 1489, 141-158.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 141-158
    • Summerton, J.1
  • 26
    • 0035113736 scopus 로고    scopus 로고
    • Locked nucleic acid (LNA): Fine-tuning the recognition of DNA and RNA
    • Braasch, D. A., and Corey, D. R. (2001) Locked nucleic acid (LNA): fine-tuning the recognition of DNA and RNA. Chem. Biol. 8, 1-7.
    • (2001) Chem. Biol. , vol.8 , pp. 1-7
    • Braasch, D.A.1    Corey, D.R.2
  • 27
    • 0036924811 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in cells, by oligonucleotides incorporating locked nucleic acids: Effect of mRNA target sequence and chimera design
    • Braasch, D. A, Liu, Y., and Corey, D. R. (2002) Antisense inhibition of gene expression in cells, by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design. Nucleic Acids Res. 30, 5160-5167.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 5160-5167
    • Braasch, D.A.1    Liu, Y.2    Corey, D.R.3
  • 28
    • 0033799686 scopus 로고    scopus 로고
    • Preparation and applications of peptide-oligonucleotide conjugates
    • Tung, C.-H., and Stein, S. (2000) Preparation and Applications of Peptide-Oligonucleotide Conjugates, Bioconjugate Chem. 11, 605-618.
    • (2000) Bioconjugate Chem. , vol.11 , pp. 605-618
    • Tung, C.-H.1    Stein, S.2
  • 29
    • 0032213115 scopus 로고    scopus 로고
    • Tailored hydrophobic cavities in oligonucleotide-steroid conjugates
    • Letsinger, R. L., and Chaturvedi, S. (1998) Tailored hydrophobic cavities in oligonucleotide-steroid conjugates. Bioconjugate Chem. 9, 826-830.
    • (1998) Bioconjugate Chem. , vol.9 , pp. 826-830
    • Letsinger, R.L.1    Chaturvedi, S.2
  • 30
    • 0025333845 scopus 로고
    • Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates
    • Shea, R. G., Marsters, J. C., and Bischofberger, N. (1990) Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates. Nucleic Acids Res. 18, 3777-3783.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3777-3783
    • Shea, R.G.1    Marsters, J.C.2    Bischofberger, N.3
  • 31
    • 0031284780 scopus 로고    scopus 로고
    • Preparation of vitamin B6-peptide and vitamin B6-peptide-oligonucleotide conjugates
    • Stein, S., and Zhu, T. (1997) Preparation of vitamin B6-peptide and vitamin B6-peptide-oligonucleotide conjugates. Methods Enzymol. 280, 51-58.
    • (1997) Methods Enzymol. , vol.280 , pp. 51-58
    • Stein, S.1    Zhu, T.2
  • 33
    • 0031984072 scopus 로고    scopus 로고
    • Trojan peptides: The penetratin system for intracellular delivery
    • Derossi, D., Chassaing, G., and Prochiantz, A. (1998) Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol. 8, 84-87.
    • (1998) Trends Cell Biol. , vol.8 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3
  • 34
    • 0029079310 scopus 로고
    • Vector-mediated delivery of a polyamide (\"peptide\") nucleic acid analog through the blood-brain barrier in vivo
    • Pardridge, W. M., Boado, R. J., and Kang, Y.-S. (1995) Vector-mediated delivery of a polyamide (\"peptide\") nucleic acid analog through the blood-brain barrier in vivo. Proc. Natl. Acad. Sci. USA. 92, 5592-5596.
    • (1995) Proc. Natl. Acad. Sci. USA. , vol.92 , pp. 5592-5596
    • Pardridge, W.M.1    Boado, R.J.2    Kang, Y.-S.3
  • 35
    • 0032859928 scopus 로고    scopus 로고
    • A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA
    • Branden, L. J., Mohamed, A. J., and Smith, C. I. E. (1999) A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat. Biotechnol. 17, 784-787.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 784-787
    • Branden, L.J.1    Mohamed, A.J.2    Smith, C.I.E.3
  • 36
    • 0036009643 scopus 로고    scopus 로고
    • Protamine-fragment peptides fused to an SV40 nuclear localization signal deliver oligonucleotides that produce antisense effects in prostate and bladder carcinoma cells
    • Benimetskaya, L., Guzzo-Pernell, N., Liu, S. T., Lai, J. C., Miller, P., and Stein, C. A. (2002) Protamine-fragment peptides fused to an SV40 nuclear localization signal deliver oligonucleotides that produce antisense effects in prostate and bladder carcinoma cells. Bioconjugate Chem. 13, 177-187.
    • (2002) Bioconjugate Chem. , vol.13 , pp. 177-187
    • Benimetskaya, L.1    Guzzo-Pernell, N.2    Liu, S.T.3    Lai, J.C.4    Miller, P.5    Stein, C.A.6
  • 37
    • 0036298282 scopus 로고    scopus 로고
    • Conjugates of antisense oligonucleotides with the tat and antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions
    • Astriab-Fisher, A., Sergueev, D., Fisher, M., Shaw, B. R., and Juliano, R. L. (2002) Conjugates of Antisense Oligonucleotides with the Tat and Antennapedia Cell-Penetrating Peptides: Effects on Cellular Uptake, Binding to Target Sequences, and Biologic Actions. Pharm. Res. 19, 744-754.
    • (2002) Pharm. Res. , vol.19 , pp. 744-754
    • Astriab-Fisher, A.1    Sergueev, D.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 38
    • 0037151062 scopus 로고    scopus 로고
    • Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis
    • Fisher, A. A., Ye, D., Sergueev, D. S., Fisher, M. H., Shaw, B. R., and Juliano, R. L. (2002) Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. J. Biol. Chem. 277, 22980-22984.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22980-22984
    • Fisher, A.A.1    Ye, D.2    Sergueev, D.S.3    Fisher, M.H.4    Shaw, B.R.5    Juliano, R.L.6
  • 39
    • 0025398291 scopus 로고
    • Biological activity of oligonucleotide-poly(L-lysine) conjugates: Mechanism of cell uptake
    • Leonetti, J. P., Degols, G., and Lebleu, B. (1990) Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake. Bioconjugate Chem. 1, 149-153.
    • (1990) Bioconjugate Chem. , vol.1 , pp. 149-153
    • Leonetti, J.P.1    Degols, G.2    Lebleu, B.3
  • 40
    • 0027034899 scopus 로고
    • Poly(L-lysine)-conjugated oligonucleotides promote sequence-specific inhibition of acute HIV-1 infection
    • Degols, G., Leonetti, J. P., Benkirane, M., Devaux, C., and Lebleu, B. (1992) Poly(L-lysine)-conjugated oligonucleotides promote sequence-specific inhibition of acute HIV-1 infection. Antisense Res. Dev. 2, 293-301.
    • (1992) Antisense Res. Dev. , vol.2 , pp. 293-301
    • Degols, G.1    Leonetti, J.P.2    Benkirane, M.3    Devaux, C.4    Lebleu, B.5
  • 41
    • 0027417416 scopus 로고
    • Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation
    • Clarenc, J. P., Degols, G., Leonetti, J. P., Milhaud, P., and Lebleu, B. (1993) Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation. Anti-Cancer Drug Des. 8, 81-94.
    • (1993) Anti-Cancer Drug Des. , vol.8 , pp. 81-94
    • Clarenc, J.P.1    Degols, G.2    Leonetti, J.P.3    Milhaud, P.4    Lebleu, B.5
  • 42
    • 0031044157 scopus 로고    scopus 로고
    • Folic acid-polylysine carrier improves efficacy of c-myc antisense oligodeoxynucleotides on human melanoma (M14) cells
    • Ginobbi, P., Geiser, T. A., Ombres, D., and Citro, G. (1997) Folic acid-polylysine carrier improves efficacy of c-myc antisense oligodeoxynucleotides on human melanoma (M14) cells. Anticancer Res. 17, 29-35.
    • (1997) Anticancer Res. , vol.17 , pp. 29-35
    • Ginobbi, P.1    Geiser, T.A.2    Ombres, D.3    Citro, G.4
  • 44
    • 0025755183 scopus 로고
    • Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence
    • Eritja, R., Pons, A., Escarceller, M., Giralt, E., and Albericio, F. (1991) Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence. Tetrahedron 47, 4113-4120.
    • (1991) Tetrahedron , vol.47 , pp. 4113-4120
    • Eritja, R.1    Pons, A.2    Escarceller, M.3    Giralt, E.4    Albericio, F.5
  • 45
    • 0028114851 scopus 로고
    • Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide
    • Bongartz, J. P., Aubertin, A. M., Milhaud, P. G., and Lebleu, B. (1994) Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide. Nucleic Acids Res. 22, 4681-4688.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4681-4688
    • Bongartz, J.P.1    Aubertin, A.M.2    Milhaud, P.G.3    Lebleu, B.4
  • 46
    • 0029136053 scopus 로고
    • Strand invasion by oligonucleotide-nuclease conjugates
    • Corey, D. R., Munoz-Medellin, D., and Huang, A. (1995) Strand invasion by oligonucleotide-nuclease conjugates. Bioconjugate Chem. 6, 93-100.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 93-100
    • Corey, D.R.1    Munoz-Medellin, D.2    Huang, A.3
  • 47
    • 0023664582 scopus 로고
    • Preparation of base-modified nucleosides suitable for non-radioactive label attachment and their incorporation into synthetic oligodeoxyribonucleotides
    • Haralambidis, J., Chai, M., and Tregear, G. W. (1987) Preparation of base-modified nucleosides suitable for non-radioactive label attachment and their incorporation into synthetic oligodeoxyribonucleotides. Nucleic Acids Res. 15, 4857-4876.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 4857-4876
    • Haralambidis, J.1    Chai, M.2    Tregear, G.W.3
  • 48
    • 7444234872 scopus 로고    scopus 로고
    • A method for solid-phase synthesis of oligonucleotide 5́-peptide-conjugates using acid-labile alpha-amino protections
    • Zaramella, S., Yeheskiely, E., and Stromberg, R. (2004) A method for solid-phase synthesis of oligonucleotide 5́-peptide-conjugates using acid-labile alpha-amino protections. J. Am. Chem. Soc. 126, 14029-14035.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 14029-14035
    • Zaramella, S.1    Yeheskiely, E.2    Stromberg, R.3
  • 50
    • 0030734127 scopus 로고    scopus 로고
    • 2′- and 3′-cholesterol-conjugated adenosine and cytosine nucleoside building blocks: Synthesis of lipidic nucleic acids
    • Manoharan, M., Inamati, G., Tivel, K. L., Conklin, B., Ross, B. S., and Cook, P. D. (1997) 2′- and 3′-cholesterol-conjugated adenosine and cytosine nucleoside building blocks: synthesis of lipidic nucleic acids. Nucleosides Nucleotides 16, 1141-1143.
    • (1997) Nucleosides Nucleotides , vol.16 , pp. 1141-1143
    • Manoharan, M.1    Inamati, G.2    Tivel, K.L.3    Conklin, B.4    Ross, B.S.5    Cook, P.D.6
  • 51
    • 0035951283 scopus 로고    scopus 로고
    • Synthesis of 2′-modified oligodeoxynucleotides via on-column conjugation
    • Hwang, J.-T., and Greenberg, M. M. (2001) Synthesis of 2′-Modified Oligodeoxynucleotides via On-Column Conjugation. J. Org. Chem. 66, 363-369.
    • (2001) J. Org. Chem. , vol.66 , pp. 363-369
    • Hwang, J.-T.1    Greenberg, M.M.2
  • 52
    • 6344248738 scopus 로고    scopus 로고
    • Oligonucleotides with 2′-O-carboxymethyl group: Synthesis and 2′-conjugation via amide bond formation on solid phase
    • Kachalova, A., Zubin, E., Stetsenko, D., Gait, M., and Oretskaya, T. (2004) Oligonucleotides with 2′-O-carboxymethyl group: synthesis and 2′-conjugation via amide bond formation on solid phase. Org. Biomol. Chem. 2, 2793-2797.
    • (2004) Org. Biomol. Chem. , vol.2 , pp. 2793-2797
    • Kachalova, A.1    Zubin, E.2    Stetsenko, D.3    Gait, M.4    Oretskaya, T.5
  • 53
    • 1342327656 scopus 로고    scopus 로고
    • A novel concept for ligand attachment to oligonucleotides via a 2′-succinyl linker
    • Winkler, J., Urban, E., Losert, D., Wacheck, V., Pehamberger, H., and Noe, C. R. (2004) A novel concept for ligand attachment to oligonucleotides via a 2′-succinyl linker. Nucleic Acids Res. 32, 710-718.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 710-718
    • Winkler, J.1    Urban, E.2    Losert, D.3    Wacheck, V.4    Pehamberger, H.5    Noe, C.R.6
  • 54
    • 0025758730 scopus 로고
    • Internucleotide phosphite sulfurization with tetraethylthiuram disulfide. Phosphorothioate oligonucleotide synthesis via phosphoramidite chemistry
    • Vu, H., and Hirschbein, B. L. (1991) Internucleotide phosphite sulfurization with tetraethylthiuram disulfide. Phosphorothioate oligonucleotide synthesis via phosphoramidite chemistry. Tetrahedron Lett. 32, 3005-3008.
    • (1991) Tetrahedron Lett. , vol.32 , pp. 3005-3008
    • Vu, H.1    Hirschbein, B.L.2
  • 55
    • 0027240210 scopus 로고
    • Matrix-assisted laser desorption ionization time-of-flight mass spectrometry: A powerful tool for the mass and sequence analysis of natural and modified oligonucleotides
    • Pieles, U., Zurcher, W., Schar, M., and Moser, H. E. (1993) Matrix-assisted laser desorption ionization time-of-flight mass spectrometry: a powerful tool for the mass and sequence analysis of natural and modified oligonucleotides. Nucleic Acids Res. 21, 3191-3196.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 3191-3196
    • Pieles, U.1    Zurcher, W.2    Schar, M.3    Moser, H.E.4
  • 58
    • 0029159058 scopus 로고
    • Preparation and characterization of antisense oligonucleotide-peptide hybrids containing viral fusion peptides
    • Soukchareun, S., Tregear, G. W., and Haralambidis, J. (1995) Preparation and characterization of antisense oligonucleotide-peptide hybrids containing viral fusion peptides. Bioconjugate Chem. 6, 43-53.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 43-53
    • Soukchareun, S.1    Tregear, G.W.2    Haralambidis, J.3
  • 59
    • 0033229989 scopus 로고    scopus 로고
    • Synthesis and binding properties of oligonucleotides carrying nuclear localization sequences
    • de La Torre, B. G., Albericio, F., Saison-Behmoaras, E., Bachi, A., and Eritja, R. (1999) Synthesis and binding properties of oligonucleotides carrying nuclear localization sequences. Bioconjugate Chem. 10, 1005-1012.
    • (1999) Bioconjugate Chem. , vol.10 , pp. 1005-1012
    • De La Torre, B.G.1    Albericio, F.2    Saison-Behmoaras, E.3    Bachi, A.4    Eritja, R.5
  • 60
    • 33748811528 scopus 로고    scopus 로고
    • Investigations on solid-phase peptide synthesis in N-to-C direction (inverse synthesis)
    • Henkel, B., Zhang, L., and Bayer, E. (1997) Investigations on solid-phase peptide synthesis in N-to-C direction (inverse synthesis). Liebigs Annalen / Recueil. 2161-2168.
    • (1997) Liebigs Annalen / Recueil. , pp. 2161-2168
    • Henkel, B.1    Zhang, L.2    Bayer, E.3
  • 61
    • 0036579872 scopus 로고    scopus 로고
    • N-to-C solid-phase peptide and peptide trifluoromethylketone synthesis using amino acid tert-butyl esters
    • Gutheil, W. G., and Xu, Q. (2002) N-to-C solid-phase peptide and peptide trifluoromethylketone synthesis using amino acid tert-butyl esters. Chem. Pharm. Bull. 50, 688-691.
    • (2002) Chem. Pharm. Bull. , vol.50 , pp. 688-691
    • Gutheil, W.G.1    Xu, Q.2
  • 62
    • 7444234872 scopus 로고    scopus 로고
    • A method for solid-phase synthesis of oligonucleotide 5′-peptide-conjugates using acid-labile alpha-ammo protections
    • Zaramella, S., Yeheskiely, E., and Stromberg, R. (2004) A method for solid-phase synthesis of oligonucleotide 5′-peptide-conjugates using acid-labile alpha-ammo protections. J. Am. Chem. Soc. 126, 14029-14035.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 14029-14035
    • Zaramella, S.1    Yeheskiely, E.2    Stromberg, R.3
  • 63
    • 0030769388 scopus 로고    scopus 로고
    • CD, absorption and thermodynamic analysis of repeating dinucleotide DNA, RNA and hybrid duplexes [d/r(AC)]12.[d/r(GT/U)] 12 and the influence of phosphorothioate substitution
    • Clark, C. L., Cecil, P. K, Singh, D., and Gray, D. M. (1997) CD, absorption and thermodynamic analysis of repeating dinucleotide DNA, RNA and hybrid duplexes [d/r(AC)]12.[d/r(GT/U)] 12 and the influence of phosphorothioate substitution. Nucleic Acids Res. 25, 4098-4105.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4098-4105
    • Clark, C.L.1    Cecil, P.K.2    Singh, D.3    Gray, D.M.4
  • 64
    • 0014592230 scopus 로고
    • Computed circular dichroism spectra for the evaluation of protein conformation
    • Greenfield, N. J., and Fasman, G. D. (1969) Computed circular dichroism spectra for the evaluation of protein conformation. Biochemistry. 8, 4108-4116.
    • (1969) Biochemistry , vol.8 , pp. 4108-4116
    • Greenfield, N.J.1    Fasman, G.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.