메뉴 건너뛰기




Volumn 2, Issue 10, 2003, Pages 1031-1043

G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; ANTISENSE OLIGONUCLEOTIDE; BROXURIDINE; COLORING AGENT; DNA; ENZYME INHIBITOR; GUANOSINE; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEOTIDE; OBLIMERSEN; OLIGONUCLEOTIDE; REACTIVE OXYGEN METABOLITE;

EID: 1042275580     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (51)

References (36)
  • 1
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124: 1-6, 1994. (Pubitemid 24054605)
    • (1994) Journal of Cell Biology , vol.124 , Issue.1-2 , pp. 1-6
    • Reed, J.C.1
  • 2
    • 0028958030 scopus 로고
    • Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
    • Reed, J. C. Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol. Oncol. Clin. N. Am., 9: 451-473, 1995.
    • (1995) Hematol. Oncol. Clin. N. Am. , vol.9 , pp. 451-473
    • Reed, J.C.1
  • 4
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenberry, D., Nunez, G., Milliman, C., Schreiber, R., and Krosmeyer, S. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature, 348: 334, 1990.
    • (1990) Nature , vol.348 , pp. 334
    • Hockenberry, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.4    Krosmeyer, S.5
  • 5
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membranes
    • Krajewski, S., Tanaka, S., and Takayama, S. Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membranes. Cancer Res., 53: 4701, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4701
    • Krajewski, S.1    Tanaka, S.2    Takayama, S.3
  • 7
    • 0029760303 scopus 로고    scopus 로고
    • Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types
    • Zhu, W., Cowie, A., and Wasfy, G. Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. EMBO J., 15: 4130, 1996.
    • (1996) EMBO J. , vol.15 , pp. 4130
    • Zhu, W.1    Cowie, A.2    Wasfy, G.3
  • 8
    • 0030779846 scopus 로고    scopus 로고
    • Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2
    • Schlesinger, P., Gross, A., and Yin, X. Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc. Natl. Acad. Sci. USA, 94: 11357, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11357
    • Schlesinger, P.1    Gross, A.2    Yin, X.3
  • 9
    • 0032587982 scopus 로고    scopus 로고
    • Bcl-x(L) prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
    • DOI 10.1016/S1097-2765(00)80307-X
    • Vander Heiden, M., Chandel, N., Schumacker, P., and Thompson, C. Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange. Mol. Cell, 3: 159-167, 1999. (Pubitemid 29292617)
    • (1999) Molecular Cell , vol.3 , Issue.2 , pp. 159-167
    • Vander, H.M.G.1    Chandel, N.S.2    Schumacker, P.T.3    Thompson, C.B.4
  • 10
    • 0027485461 scopus 로고
    • Bcl-2 functions in an antioxidant pathway to prevent apoptosis
    • DOI 10.1016/0092-8674(93)80066-N
    • Hockenberry, D., Oltvai, Z., Yin, X., Milliman, C., and Krosmeyer, S. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell, 75: 241-251, 1993. (Pubitemid 23320288)
    • (1993) Cell , vol.75 , Issue.2 , pp. 241-251
    • Hockenbery, D.M.1    Oltvai, Z.N.2    Yin, X.-M.3    Milliman, C.L.4    Korsmeyer, S.J.5
  • 13
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita, T. and Reed, R. C. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood, 81: 151-157, 1993. (Pubitemid 23013689)
    • (1993) Blood , vol.81 , Issue.1 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 14
    • 0027196091 scopus 로고
    • Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis
    • Walton, M. I., Whysong, D., O'Connor, P. M., Hockenberry, D., Korsmeyer S. J., and Kohn, K. W. Constitutive expression of human Bcl-2 modulates nitrogen mustard and campothecin induced apoptosis. Cancer Res., 53: 1853-1861, 1993. (Pubitemid 23127114)
    • (1993) Cancer Research , vol.53 , Issue.8 , pp. 1853-1861
    • Walton, M.I.1    Whysong, D.2    O'Connor, P.M.3    Hockenbery, D.4    Korsmeyer, S.J.5    Kohn, K.W.6
  • 15
    • 0027892521 scopus 로고
    • bcl-2 Protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
    • Kamesaki, S., Kamesaki, H., Jorgensen, T. J., Tanizawa, A., Pommier, Y., and Cossman, J. Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res., 53: 4251-4256, 1993. (Pubitemid 24146774)
    • (1993) Cancer Research , vol.53 , Issue.18 , pp. 4251-4256
    • Kamesaki, S.1    Kamesaki, H.2    Jorgensen, T.J.3    Tanizawa, A.4    Pommier, Y.5    Cossman, J.6
  • 17
    • 0029157380 scopus 로고
    • Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 protooncogene expression in human breast cancer cells
    • Teixeira, C., Reed, J. C., and Pratt, M. A. Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 protooncogene expression in human breast cancer cells. Cancer Res., 55: 3902-3907, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3902-3907
    • Teixeira, C.1    Reed, J.C.2    Pratt, M.A.3
  • 18
    • 0032422126 scopus 로고    scopus 로고
    • Estrogen withdrawal-induced human breast cancer tumour regression in nude mice is prevented by Bcl-2
    • DOI 10.1016/S0014-5793(98)01499-9, PII S0014579398014999
    • Pratt, M. A., Krajewski, S., Menard, M., Krajewski, M., Macleod, H., and Reed, J. C. Estrogen withdrawal-induced human breast cancer tumor regression in nude mice is prevented by Bcl-2. FEBS Lett., 440: 403-408, 1998. (Pubitemid 29052323)
    • (1998) FEBS Letters , vol.440 , Issue.3 , pp. 403-408
    • Pratt, M.A.C.1    Krajewski, S.2    Menard, M.3    Krajewska, M.4    Macleod, H.5    Reed, J.C.6
  • 19
    • 0032817236 scopus 로고    scopus 로고
    • A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells
    • DOI 10.1002/(SICI)1097-0215(19990909)82:6<846::AID
    • Dorai, T., Perlman, H., Walsh, K., Shabsigh, A., Golubof, E. T., Olsson, C. A., and Buttyan, R. A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells. Int. J. Cancer, 82: 846-852, 1999. (Pubitemid 29384336)
    • (1999) International Journal of Cancer , vol.82 , Issue.6 , pp. 846-852
    • Dorai, T.1    Perlman, H.2    Walsh, K.3    Shabsigh, A.4    Goluboff, E.T.5    Olsson, C.A.6    Buttyan, R.7
  • 22
    • 0027217846 scopus 로고
    • Investigations of antisense oligonucleotides targeted against bcl-2 RNAs
    • Kitada, S., Miyashita, T., Tanaka, S., and Reed, J. C. Investigations of antisense oligonucleotides targeted against bcl-2 RNAs. Antisense Res. Dev., 3: 157-169, 1993. (Pubitemid 23243676)
    • (1993) Antisense Research and Development , vol.3 , Issue.2 , pp. 157-169
    • Kitada, S.1    Miyashita, T.2    Tanaka, S.3    Reed, J.C.4
  • 23
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
    • Stein, C. A. and Cheng, Y. C. Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science, 261: 1004-1012, 1993. (Pubitemid 23300859)
    • (1993) Science , vol.261 , Issue.5124 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.-C.2
  • 24
    • 0000015743 scopus 로고    scopus 로고
    • The use of antisense oligonucleotides to validate gene function
    • Dias, N. and Stein, CA. The use of antisense oligonucleotides to validate gene function. Mol. Cancer Ther., 1: 347-355, 2001.
    • (2001) Mol. Cancer Ther. , vol.1 , pp. 347-355
    • Dias, N.1    Stein, C.A.2
  • 25
    • 0033748335 scopus 로고    scopus 로고
    • Effects of Bcl-2 modulation with G3139 antisense oligonucleotide on human breast cancer cells are independent of inherent Bcl-2 protein expression
    • Chi, K., Wallis, A. E., Lee, C. H., De Menezes, D. L., Sartor, J., Dragowska, W. H., and Mayer, L. D. Effects of Bcl-2 modulation with G3139 antisense oligonucleotide on human breast cancer cells are independent of inherent Bcl-2 protein expression. Breast Cancer Res. Treat., 63: 199-212, 2000.
    • (2000) Breast Cancer Res. Treat. , vol.63 , pp. 199-212
    • Chi, K.1    Wallis, A.E.2    Lee, C.H.3    De Menezes, D.L.4    Sartor, J.5    Dragowska, W.H.6    Mayer, L.D.7
  • 26
    • 15444340598 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer
    • Miyake, H., Hanada, N., Nakamura, H., Kagawa, S., Fujiwara, T., Hara, I., Eto, H., Gohji, K., Arakawa, S., Kamidono, S., and Saya, H. Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer. Oncogene, 16: 933-943, 1998. (Pubitemid 28102597)
    • (1998) Oncogene , vol.16 , Issue.7 , pp. 933-943
    • Miyake, H.1    Hanada, N.2    Nakamura, H.3    Kagawa, S.4    Fujiwara, T.5    Hara, I.6    Eto, H.7    Gohji, K.8    Arakawa, S.9    Kamidono, S.10    Saya, H.11
  • 27
    • 0034606686 scopus 로고    scopus 로고
    • Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides
    • Miyake, H., Tolcher, A., and Gleave, M. E. Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides. J. Natl. Cancer Inst., 92: 34-41, 2000. (Pubitemid 30082226)
    • (2000) Journal of the National Cancer Institute , vol.92 , Issue.1 , pp. 34-41
    • Miayake, H.1    Tolcher, A.2    Gleave, M.E.3
  • 28
    • 0028815149 scopus 로고
    • Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
    • Guvakova, M. A., Yakubov, L. A., Vlodavsky, I., Tonkinson, J. L., and Stein, C. A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J. Biol. Chem., 270: 2620-2627, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2620-2627
    • Guvakova, M.A.1    Yakubov, L.A.2    Vlodavsky, I.3    Tonkinson, J.L.4    Stein, C.A.5
  • 29
    • 0029919656 scopus 로고    scopus 로고
    • Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides
    • Khaled, Z., Benimetskaya, L., Zeltser, R., Khan, T., Sharma, H. W., Narayanan, R., and Stein, C. A. Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res., 24: 737-745, 1996.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 737-745
    • Khaled, Z.1    Benimetskaya, L.2    Zeltser, R.3    Khan, T.4    Sharma, H.W.5    Narayanan, R.6    Stein, C.A.7
  • 30
    • 0035213894 scopus 로고    scopus 로고
    • Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-α (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligodeoxynucleotides: Relationship to the decreased viability of T24 bladder and PC3 prostate cancer cells
    • Benimetskaya, L., Miller, P., Benimetsky, S., Maciaszek, A., Guga, P., Beaucage, S. L., Wilk, A., Grajkowski, A., Halperin, A. L., and Stein, C. A. Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-α (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligonucleotides: relationship to the decreased viability of T24 Bladder and PC3 prostate cancer cells. Mol. Pharmacol., 60: 1296-1307, 2001. (Pubitemid 33144901)
    • (2001) Molecular Pharmacology , vol.60 , Issue.6 , pp. 1296-1307
    • Benimetskaya, L.1    Miller, P.2    Benimetsky, S.3    Maciaszek, A.4    Guga, P.5    Beaucage, S.L.6    Wilk, A.7    Grajkowski, A.8    Halperin, A.L.9    Stein, C.A.10
  • 31
    • 0035800889 scopus 로고    scopus 로고
    • Methods of detection of vascular reactive species: Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite
    • Tarpey, M. M. and Fridovich, I. Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ. Res., 89: 224-236, 2001. (Pubitemid 34133992)
    • (2001) Circulation Research , vol.89 , Issue.3 , pp. 224-236
    • Tarpey, M.M.1    Fridovich, I.2
  • 32
    • 0030020154 scopus 로고    scopus 로고
    • Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1 treated rat liver and human oral mucosal cells
    • Yarborough, A., Zhang, Y. J., Hsu, T. M., and Santella, R. M. Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1 treated rat liver and human oral mucosal cells. Cancer Res., 56: 683-688, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 683-688
    • Yarborough, A.1    Zhang, Y.J.2    Hsu, T.M.3    Santella, R.M.4
  • 35
    • 0033539046 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol α expression during early S phase
    • DOI 10.1038/sj.onc.1202900
    • Simbulan-Rosenthal, C. M., Rosenthal, D. S., Luo, R., and Smulson, M. E. Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol a expression during early S phase, Oncogene. 18: 5015-5023, 1999. (Pubitemid 29443747)
    • (1999) Oncogene , vol.18 , Issue.36 , pp. 5015-5023
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.S.2    Luo, R.3    Smulson, M.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.