-
1
-
-
0028040019
-
Bcl-2 and the regulation of programmed cell death
-
Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124: 1-6, 1994. (Pubitemid 24054605)
-
(1994)
Journal of Cell Biology
, vol.124
, Issue.1-2
, pp. 1-6
-
-
Reed, J.C.1
-
2
-
-
0028958030
-
Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
-
Reed, J. C. Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol. Oncol. Clin. N. Am., 9: 451-473, 1995.
-
(1995)
Hematol. Oncol. Clin. N. Am.
, vol.9
, pp. 451-473
-
-
Reed, J.C.1
-
3
-
-
0032504581
-
Bcl-2 family proteins and mitochondria
-
DOI 10.1016/S0005-2728(98)00108-X, PII S000527289800108X
-
Reed, J. C., Jurgensmeier, J. M., and Matsuyama, S. Bcl-2 family proteins and mitochondria. Biochim. Biophys. Acta, 1366: 127-137, 1998. (Pubitemid 28467027)
-
(1998)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1366
, Issue.1-2
, pp. 127-137
-
-
Reed, J.C.1
Jurgensmeier, J.M.2
Matsuyama, S.3
-
4
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenberry, D., Nunez, G., Milliman, C., Schreiber, R., and Krosmeyer, S. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature, 348: 334, 1990.
-
(1990)
Nature
, vol.348
, pp. 334
-
-
Hockenberry, D.1
Nunez, G.2
Milliman, C.3
Schreiber, R.4
Krosmeyer, S.5
-
5
-
-
0027362667
-
Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membranes
-
Krajewski, S., Tanaka, S., and Takayama, S. Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membranes. Cancer Res., 53: 4701, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4701
-
-
Krajewski, S.1
Tanaka, S.2
Takayama, S.3
-
6
-
-
0028157171
-
Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells
-
De Jong, D., Prins, F., and Mason, D. Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells. Cancer Res., 54: 256-260, 1994. (Pubitemid 24042119)
-
(1994)
Cancer Research
, vol.54
, Issue.1
, pp. 256-260
-
-
De Jong, D.1
Prins, F.A.2
Mason, D.Y.3
Reed, J.C.4
Van Ommen, G.B.5
Kluin, P.M.6
-
7
-
-
0029760303
-
Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types
-
Zhu, W., Cowie, A., and Wasfy, G. Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. EMBO J., 15: 4130, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 4130
-
-
Zhu, W.1
Cowie, A.2
Wasfy, G.3
-
8
-
-
0030779846
-
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2
-
Schlesinger, P., Gross, A., and Yin, X. Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc. Natl. Acad. Sci. USA, 94: 11357, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11357
-
-
Schlesinger, P.1
Gross, A.2
Yin, X.3
-
9
-
-
0032587982
-
Bcl-x(L) prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
-
DOI 10.1016/S1097-2765(00)80307-X
-
Vander Heiden, M., Chandel, N., Schumacker, P., and Thompson, C. Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange. Mol. Cell, 3: 159-167, 1999. (Pubitemid 29292617)
-
(1999)
Molecular Cell
, vol.3
, Issue.2
, pp. 159-167
-
-
Vander, H.M.G.1
Chandel, N.S.2
Schumacker, P.T.3
Thompson, C.B.4
-
10
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
DOI 10.1016/0092-8674(93)80066-N
-
Hockenberry, D., Oltvai, Z., Yin, X., Milliman, C., and Krosmeyer, S. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell, 75: 241-251, 1993. (Pubitemid 23320288)
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.-M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
11
-
-
0027318190
-
bcl-2 inhibits death of central neural cells induced by multiple agents
-
Zhong, L., Sarafian, T., Kane, D., Charles, A., Mah, S., Edwards, R., and Bredesen, D. Bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. Natl. Acad. Sci. USA, 90: 4533-4537, 1993. (Pubitemid 23148939)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.10
, pp. 4533-4537
-
-
Zhong, L.-T.1
Sarafian, T.2
Kane, D.J.3
Charles, A.C.4
Mah, S.P.5
Edwards, R.H.6
Bredesen, D.E.7
-
12
-
-
0027717968
-
Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
-
Kane, D., Sarafian, T., Anton, R., Hahn, H., Gralla, E., Valentine, J., Ord, T., and Bredesen, D. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science, 262: 1274-1277, 1993. (Pubitemid 24036095)
-
(1993)
Science
, vol.262
, Issue.5137
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
Hahn, H.4
Gralla, E.B.5
Valentine, J.S.6
Ord, T.7
Bredesen, D.E.8
-
13
-
-
0027389763
-
Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
-
Miyashita, T. and Reed, R. C. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood, 81: 151-157, 1993. (Pubitemid 23013689)
-
(1993)
Blood
, vol.81
, Issue.1
, pp. 151-157
-
-
Miyashita, T.1
Reed, J.C.2
-
14
-
-
0027196091
-
Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis
-
Walton, M. I., Whysong, D., O'Connor, P. M., Hockenberry, D., Korsmeyer S. J., and Kohn, K. W. Constitutive expression of human Bcl-2 modulates nitrogen mustard and campothecin induced apoptosis. Cancer Res., 53: 1853-1861, 1993. (Pubitemid 23127114)
-
(1993)
Cancer Research
, vol.53
, Issue.8
, pp. 1853-1861
-
-
Walton, M.I.1
Whysong, D.2
O'Connor, P.M.3
Hockenbery, D.4
Korsmeyer, S.J.5
Kohn, K.W.6
-
15
-
-
0027892521
-
bcl-2 Protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
-
Kamesaki, S., Kamesaki, H., Jorgensen, T. J., Tanizawa, A., Pommier, Y., and Cossman, J. Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res., 53: 4251-4256, 1993. (Pubitemid 24146774)
-
(1993)
Cancer Research
, vol.53
, Issue.18
, pp. 4251-4256
-
-
Kamesaki, S.1
Kamesaki, H.2
Jorgensen, T.J.3
Tanizawa, A.4
Pommier, Y.5
Cossman, J.6
-
16
-
-
0028029834
-
High levels of p26BCL-2 oncoprotein retard taxol-induced apoptosis in human pre-B leukemia cells
-
Tang, C., Willingham, M. C., Reed, J. C., Miyashita, T., Ray, S., Ponnathpur, V., Huang, Y., Mahoney, M. E., Bullock, G., and Bhalla, K. High levels of p26BCL-2 oncoprotein retard taxol-induced apoptosis in human pre-B leukemia cells. Leukemia, 8: 1960-1969, 1994.
-
(1994)
Leukemia
, vol.8
, pp. 1960-1969
-
-
Tang, C.1
Willingham, M.C.2
Reed, J.C.3
Miyashita, T.4
Ray, S.5
Ponnathpur, V.6
Huang, Y.7
Mahoney, M.E.8
Bullock, G.9
Bhalla, K.10
-
17
-
-
0029157380
-
Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 protooncogene expression in human breast cancer cells
-
Teixeira, C., Reed, J. C., and Pratt, M. A. Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 protooncogene expression in human breast cancer cells. Cancer Res., 55: 3902-3907, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 3902-3907
-
-
Teixeira, C.1
Reed, J.C.2
Pratt, M.A.3
-
18
-
-
0032422126
-
Estrogen withdrawal-induced human breast cancer tumour regression in nude mice is prevented by Bcl-2
-
DOI 10.1016/S0014-5793(98)01499-9, PII S0014579398014999
-
Pratt, M. A., Krajewski, S., Menard, M., Krajewski, M., Macleod, H., and Reed, J. C. Estrogen withdrawal-induced human breast cancer tumor regression in nude mice is prevented by Bcl-2. FEBS Lett., 440: 403-408, 1998. (Pubitemid 29052323)
-
(1998)
FEBS Letters
, vol.440
, Issue.3
, pp. 403-408
-
-
Pratt, M.A.C.1
Krajewski, S.2
Menard, M.3
Krajewska, M.4
Macleod, H.5
Reed, J.C.6
-
19
-
-
0032817236
-
A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells
-
DOI 10.1002/(SICI)1097-0215(19990909)82:6<846::AID
-
Dorai, T., Perlman, H., Walsh, K., Shabsigh, A., Golubof, E. T., Olsson, C. A., and Buttyan, R. A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells. Int. J. Cancer, 82: 846-852, 1999. (Pubitemid 29384336)
-
(1999)
International Journal of Cancer
, vol.82
, Issue.6
, pp. 846-852
-
-
Dorai, T.1
Perlman, H.2
Walsh, K.3
Shabsigh, A.4
Goluboff, E.T.5
Olsson, C.A.6
Buttyan, R.7
-
20
-
-
0031907428
-
bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
DOI 10.1038/nm0298-232
-
Jansen, B., Schalgbauer-Wadl, H., Brown, B. D., Bryan, R. N., van Elsas, A., Muller, M., Wolff, K., Eichler, H.G., and Pehamberger, H. Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat. Med., 4: 232-234, 1998. (Pubitemid 28137379)
-
(1998)
Nature Medicine
, vol.4
, Issue.2
, pp. 232-234
-
-
Jansen, B.1
Schlagbauer-Wadl, H.2
Brown, B.D.3
Bryan, R.N.4
Van Elsas, A.5
Muller, M.6
Wolff, K.7
Eichler, H.-G.8
Pehamberger, H.9
-
21
-
-
0034684471
-
Chemosensitization of malignant melanoma by BCL2 antisense therapy
-
Jansen, B., Wacheck, V., Heere-Ress, E., Schalgbauer-Wadl, H., Hoeller, C., Lucas, T., Hoermann, M., Hollenstein, U., Wolff, K., and Pehamberger, H. Chemosensitization of malignant melanoma by BCL2 antisense therapy. Lancet, 356: 1728-1733, 2000.
-
(2000)
Lancet
, vol.356
, pp. 1728-1733
-
-
Jansen, B.1
Wacheck, V.2
Heere-Ress, E.3
Schalgbauer-Wadl, H.4
Hoeller, C.5
Lucas, T.6
Hoermann, M.7
Hollenstein, U.8
Wolff, K.9
Pehamberger, H.10
-
22
-
-
0027217846
-
Investigations of antisense oligonucleotides targeted against bcl-2 RNAs
-
Kitada, S., Miyashita, T., Tanaka, S., and Reed, J. C. Investigations of antisense oligonucleotides targeted against bcl-2 RNAs. Antisense Res. Dev., 3: 157-169, 1993. (Pubitemid 23243676)
-
(1993)
Antisense Research and Development
, vol.3
, Issue.2
, pp. 157-169
-
-
Kitada, S.1
Miyashita, T.2
Tanaka, S.3
Reed, J.C.4
-
23
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
Stein, C. A. and Cheng, Y. C. Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science, 261: 1004-1012, 1993. (Pubitemid 23300859)
-
(1993)
Science
, vol.261
, Issue.5124
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.-C.2
-
24
-
-
0000015743
-
The use of antisense oligonucleotides to validate gene function
-
Dias, N. and Stein, CA. The use of antisense oligonucleotides to validate gene function. Mol. Cancer Ther., 1: 347-355, 2001.
-
(2001)
Mol. Cancer Ther.
, vol.1
, pp. 347-355
-
-
Dias, N.1
Stein, C.A.2
-
25
-
-
0033748335
-
Effects of Bcl-2 modulation with G3139 antisense oligonucleotide on human breast cancer cells are independent of inherent Bcl-2 protein expression
-
Chi, K., Wallis, A. E., Lee, C. H., De Menezes, D. L., Sartor, J., Dragowska, W. H., and Mayer, L. D. Effects of Bcl-2 modulation with G3139 antisense oligonucleotide on human breast cancer cells are independent of inherent Bcl-2 protein expression. Breast Cancer Res. Treat., 63: 199-212, 2000.
-
(2000)
Breast Cancer Res. Treat.
, vol.63
, pp. 199-212
-
-
Chi, K.1
Wallis, A.E.2
Lee, C.H.3
De Menezes, D.L.4
Sartor, J.5
Dragowska, W.H.6
Mayer, L.D.7
-
26
-
-
15444340598
-
Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer
-
Miyake, H., Hanada, N., Nakamura, H., Kagawa, S., Fujiwara, T., Hara, I., Eto, H., Gohji, K., Arakawa, S., Kamidono, S., and Saya, H. Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer. Oncogene, 16: 933-943, 1998. (Pubitemid 28102597)
-
(1998)
Oncogene
, vol.16
, Issue.7
, pp. 933-943
-
-
Miyake, H.1
Hanada, N.2
Nakamura, H.3
Kagawa, S.4
Fujiwara, T.5
Hara, I.6
Eto, H.7
Gohji, K.8
Arakawa, S.9
Kamidono, S.10
Saya, H.11
-
27
-
-
0034606686
-
Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides
-
Miyake, H., Tolcher, A., and Gleave, M. E. Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides. J. Natl. Cancer Inst., 92: 34-41, 2000. (Pubitemid 30082226)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.1
, pp. 34-41
-
-
Miayake, H.1
Tolcher, A.2
Gleave, M.E.3
-
28
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
Guvakova, M. A., Yakubov, L. A., Vlodavsky, I., Tonkinson, J. L., and Stein, C. A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J. Biol. Chem., 270: 2620-2627, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
29
-
-
0029919656
-
Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides
-
Khaled, Z., Benimetskaya, L., Zeltser, R., Khan, T., Sharma, H. W., Narayanan, R., and Stein, C. A. Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res., 24: 737-745, 1996.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 737-745
-
-
Khaled, Z.1
Benimetskaya, L.2
Zeltser, R.3
Khan, T.4
Sharma, H.W.5
Narayanan, R.6
Stein, C.A.7
-
30
-
-
0035213894
-
Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-α (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligodeoxynucleotides: Relationship to the decreased viability of T24 bladder and PC3 prostate cancer cells
-
Benimetskaya, L., Miller, P., Benimetsky, S., Maciaszek, A., Guga, P., Beaucage, S. L., Wilk, A., Grajkowski, A., Halperin, A. L., and Stein, C. A. Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-α (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligonucleotides: relationship to the decreased viability of T24 Bladder and PC3 prostate cancer cells. Mol. Pharmacol., 60: 1296-1307, 2001. (Pubitemid 33144901)
-
(2001)
Molecular Pharmacology
, vol.60
, Issue.6
, pp. 1296-1307
-
-
Benimetskaya, L.1
Miller, P.2
Benimetsky, S.3
Maciaszek, A.4
Guga, P.5
Beaucage, S.L.6
Wilk, A.7
Grajkowski, A.8
Halperin, A.L.9
Stein, C.A.10
-
31
-
-
0035800889
-
Methods of detection of vascular reactive species: Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite
-
Tarpey, M. M. and Fridovich, I. Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ. Res., 89: 224-236, 2001. (Pubitemid 34133992)
-
(2001)
Circulation Research
, vol.89
, Issue.3
, pp. 224-236
-
-
Tarpey, M.M.1
Fridovich, I.2
-
32
-
-
0030020154
-
Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1 treated rat liver and human oral mucosal cells
-
Yarborough, A., Zhang, Y. J., Hsu, T. M., and Santella, R. M. Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1 treated rat liver and human oral mucosal cells. Cancer Res., 56: 683-688, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 683-688
-
-
Yarborough, A.1
Zhang, Y.J.2
Hsu, T.M.3
Santella, R.M.4
-
33
-
-
0034623990
-
A redox signaling mechanism for density-dependent inhibition of cell growth
-
DOI 10.1074/jbc.M007319200
-
Pani, G., Colavitti, R., Bedogni, B., Anzevino, R., Borrelo, S., and Galeotti, T. A redox signaling mechanism for density-dependent inhibition of cell growth. J. Biol. Chem., 275: 38891-38899, 2000. (Pubitemid 32010745)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.49
, pp. 38891-38899
-
-
Pani, G.1
Colavitti, R.2
Bedogni, B.3
Anzevino, R.4
Borrello, S.5
Galeotti, T.6
-
34
-
-
0024475427
-
1-S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb
-
1-S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb . Science, 245: 180-183, 1989.
-
(1989)
Science
, vol.245
, pp. 180-183
-
-
Gewirtz, A.M.1
Anfossi, G.2
Venturelli, D.3
Valpreda, S.4
Sims, R.5
Calabretta, B.6
-
35
-
-
0033539046
-
Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol α expression during early S phase
-
DOI 10.1038/sj.onc.1202900
-
Simbulan-Rosenthal, C. M., Rosenthal, D. S., Luo, R., and Smulson, M. E. Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol a expression during early S phase, Oncogene. 18: 5015-5023, 1999. (Pubitemid 29443747)
-
(1999)
Oncogene
, vol.18
, Issue.36
, pp. 5015-5023
-
-
Simbulan-Rosenthal, C.M.1
Rosenthal, D.S.2
Luo, R.3
Smulson, M.E.4
-
36
-
-
0034142182
-
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
-
Hartman, G., Weeratna, R. D., Ballas, Z. K., Payette, P., Blackwell, S., Suparto, I., Rasmussen, W. L., Waldschmidt, M., Sajuthi, D., Purcell, R. H., Davis, H. L., and Kreig, A. M. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo . J. Immunol., 164: 1617-1624, 2000. (Pubitemid 30067282)
-
(2000)
Journal of Immunology
, vol.164
, Issue.3
, pp. 1617-1624
-
-
Hartmann, G.1
Weeratna, R.D.2
Ballas, Z.K.3
Payette, P.4
Blackwell, S.5
Suparto, I.6
Rasmussen, W.L.7
Waldschmidt, M.8
Sajuthi, D.9
Purcell, R.H.10
Davis, H.L.11
Krieg, A.M.12
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