Plasticity of neuroendocrine-thymus interactions during aging

Experimental Gerontology

Volumn 32, Issue 4-5, 1997, Pages 415-429

  Fabris, N ^a,b   Mocchegiani, E ^b   Provinciali, M ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b INRCA   (Italy)

Author keywords

Aging; Melatonin; Neuroendocrine; Thymus; Zinc

Indexed keywords

GONADORELIN; GROWTH HORMONE; MELATONIN; ZINC;

AGING; CONFERENCE PAPER; ENZYME REACTIVATION; HORMONAL REGULATION; HUMAN; IMMUNOMODULATION; NEUROENDOCRINOLOGY; NEUROIMMUNOLOGY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; THYMUS; ZINC METABOLISM;

AGING; ANIMALS; HUMANS; IMMUNE SYSTEM; MELATONIN; NEUROSECRETORY SYSTEMS; THYMUS GLAND; ZINC;

ANIMALIA;

EID: 0030743791     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(96)00166-0     Document Type: Conference Paper

References (52)

1. BESEDOVSKY, H.O. and DEL REY, A. Immune-neuroendocrine circuits: Integrative role of cytokines. In: Frontiers in Neuro-endocrinology, vol. 13, Raven Press, New York, pp. 61-94, 1992.
2. BONOMO, A. and MATZINGER, P. Thymus epithelium induces tissues-specific tolerance. J. Exp. Med. 177, 1153-1155, 1993.
3. BULLOCH, K., MCEWEN, B.S., DIWA, A., RADOJCIC, T., HAUSMAN, J., and BAIRD, S. The role of calcitonin gene-related peptide in the mouse thymus revisited. Ann. NY Acad. Sci. 741, 129-136, 1994.
4. COHEN, J.J. Programmed cell death in the immune system. Adv. Immunol. 50, 55-85, 1991.
5. CUNANNE, S.C., Horrobin, D.F., Manku, M.S., and OKA, M. Alteration of tissue zinc distribution and biochemical analysis of serum following pinealectomy in the rat. Endocrinol. Rev. 6, 311-319, 1979.
6. DARDENNE, M. and SAVINO, W. Neuroendocrine circuits controlling the physiology of the thymic epithelium, Ann. NY Acad. Sci. 650, 85-91, 1992.
7. DARDENNE, M., BUKAIBA, N., GAGNERAULT, M.C., HOMO-DELARCHE, F., CHAPPUIS, P., LEMMONNIER, D., and SAVINO, W. Restoration of the thymus in aging mice by in vivo zinc supplementation. Clin. Immunol Immunopathol. 66, 127-135, 1993.
8. DARDENNE, M., PLEAU, J.M., NABAMA, B., LEFANCIER, P., DENIEN, M., CHOAY, J., and BACH, J.F Contribution of zinc and other metals to the biological activity of the serum thymic factor. Proc. Natl. Acad. Sci. USA 79, 5370-5375, 1982.
9. DAVILA, D.R., BRIEF, S., SIMON, J., HAMMER, R.E., BRINSTER, R.L., and KELLY, K.W. Role of growth hormone in regulating T-dependent immune events in aged, nude and transgenic rodents. J. Neurosci. Res. 18, 108-116, 1987.
10. FABRIS, N. and MOCCHEGIANI, E. Zinc, human diseases and aging. Review article. Aging Clin. Exp. Res. 7, 77-93, 1995.
11. FABRIS, N. and MOCCHEGIANI, E. Immunomodulating role of growth hormone. In: Growth Hormone II, Bercu, B.B., and Walker, R.F. (Editors), pp. 116-130, Springer Verlag, New York, 1994.
12. FABRIS, N. and PROVINCIALI M. Hormones. In: Natural Immunity, Nelson, D. (Editor), pp. 306-347, Academic Press, New York, 1989.
13. FABRIS, N. Biomarkers of aging in the neuroendocrine-immune domain. Time for a new theory of aging? Ann. NY Acad. Sci. 663, 335-348, 1992.
14. FABRIS, N. Neuroendocrine-thymus interactions. In: Immunopharmacology Reviews, Hadden, J., and Szentivanyi, A., (Editors), pp. 315-352, Plenum Press, New York, 1996.
15. FABRIS, N. Neuroendocrine/thymus interactions during development and aging. In: Hormones and Immunity. Bilateral Communication between the Endocrine and Immune Systems, Grossman, C. (Editor), pp. 265-299, Springer Verlag, New York, 1993.
16. FABRIS, N., MARKOVIC, B.M., SPECTOR, N.H., and JANKOVIC, B.D. Neuroimmunomodulation: The state of art. Ann. NY Acad. Sci USA 741, 1-372, 1994.
17. FABRIS, N., MOCCHEGIANI, E., AMADIO, L., ZANNOTTI, M., LICASTRO, F., and FRANCESCHI, C. Thymic hormone deficiency in normal aging and Down's syndrome: Is there a primary failure of the thymus? Lancet 1, 983-986, 1984.
18. FABRIS, N., MOCCHEGIANI, E., MARIOTTI, S., PACINI, F., and PINCHIERA, A. Thyroid function modulates thymus endocrine activity. J. Clin. Endocrinol. Metab. 62, 474-478, 1986a.
19. FABRIS, N., MOCCHEGIANI, E., MUZZIOLI, M., and PILONI, S. Recovery of age related decline of thymic endocrine activity and PHA response by lysine-arginine combination. Int. J. Immunopharmacol. 8, 677-685 1986b.
20. GEENEN, V., CORMANN-GOFFIN, N., MARTENS, H., VANDERSMISSEN, E., ROBERT, F., BENHIDA, A., LEGROS, J.J., MARTIAL, J., and FRANCHIMONT, P. Thymic neurohypophysial-related peptides and T cell selection. Regul. Pep. 45, 273-280, 1993.
21. GOFF, B.L., ROTH, J.A., ARP, L.H., and INCEFY, G.S. Growth hormone treatment stimulates thymulin production in aged dogs. Clin. Exp. Immunol. 65, 580-587, 1987.
22. GOLDSTEIN, A.L. Thymic Hormones and Lymphokines, Plenum Press, New York, 1984.
23. GREENSTEIN, B.D., FITZPATRICK, F.T., KENDALL, M.D., and WHEELER, M.J. Regeneration of the thymus in old male rats treated with a stable analogue of LHRH. J. Endocrinol. 112, 345-350, 1987.
24. HADDEN, J.W. Immunostimulants. Immunol. Today 14, 275-280, 1993.
25. IWATA, M., HANAOKA, S., and SATO, K. Rescue of thymocytes and T-cell hybridomas from glucocorticoids-induced apoptosis by stimulation via the T cell receptors/CD3 complex: A possible in vitro model for positive selection of the T cell repertoire. Eur. J. Immunol 21, 643-649, 1991.
26. KELLEY, K.W., BRIEF, S., WESTLY, H.J., NOVAKOFSKY, J., BECHITEL, P. J., SIMON, J., and WALKER, E.B. GH3 pituitary adenoma cells can reverse thymic aging in rats. Proc. Natl. Acad. Sci. USA 83, 5663-5667, 1986.
27. MADDEN, K.S. and FELTEN, D.L. Experimental basis for neural-immune interactions. Physiol. Rev. 75, 77-106, 1995.
28. MARCHIETTI, B., MORALE, M.C., BATTICANE, N., GALLO, F., FARINELLI, Z., and CIONI, M. Aging of the reproductive-neuroimmune axis. Ann. NY Acad. Sci. 621, 159-173, 1991.
29. MARTIN-CACAO, A., LOPEZ-GONZALES, M.A., CALVO, J.R. SEGURAAND, J.J., and GUERRERO, J.M. Melatonin binding sites in rat thymus during development. In: Melatonin and the Pineal Gland, Touitou, Y., Arendt, J., and Pevet, P. (Editors), pp. 379-382, Elsevier, Amsterdam, 1993.
30. MCCABE, M.J., JR., AIJIANG, S., and ORRENIUS, S. Chelation of intracellular zinc triggers apoptosis in mature thymocytes. Lab. Invest. 69, 101-110, 1993.
31. MCCANN, S.M., MILENKOVIC, L., GONZALES, M.C., LYSON, K., KARANTH, S., and RETTORI, V. Endocrine aspects of neuroimmunomodulation: Methods and Overview. In: Neurobiology of Cytokines - A Volume of Methods in Neurosciences, DeSouza, E.B. (Editors), pp. 187-201, Academic Press, Boca Raton, FL, 1993.
32. MIGLIORATI, G., NICOLETTI, F., D'ADAMIO, F., SPRECA, A. PAGLIACCI, C., and RICCARDI, C. Dexameth-asone induces apoptosis in mouse natural killer cells and cytotoxic T. lymphocytes. Immunology 81, 21-26, 1994.
33. MOCCHEGIANI, E. and FABRIS, N. Age-related thymus involution zinc reverses in vitro the thymulin secretion defect. Int. J. Immunopharmacol 17, 745-749, 1995.
34. MOCCHEGIANI, E., BUILIAN, D., SANTARELLI, L., TIBALDI, A., MUZZIOLI, M., PIERPAOLI W., and FABRIS, N. The immuno-reconstituting effect of melatonin of pineal grafting and its relation to zinc pool in aging mice. J. Neuroimmunol. 53, 189-201, 1994.
35. MOCCHEGIANI, E., SANTARELLI, L., MUZZIOLI, M., and FABRIS, N. Reversibility of the thymic involution and of age-related immune dysfunctions by zinc supplementation in old mice. Int. J. Immunopharmacol. 17, 703-718, 1995.
36. MORTON, D.J. Alteration of plasma cation levels in rats kept in costant light. J. Pineal. Res. 9, 95-101, 1990.
37. PIERI, C., MARRA, M., MORONI, F., RECCHIONI, R., and MARCHESELLI, F. MELATONIN: A peroxil radical scavenger more effective than vitamin E. Life Sci. 55, 271-276, 1994.
38. PIERPAOLI, W. and REGELSON, W. Pineal control of aging: Effect of melatonin and pineal grafting on aging mice. Proc. Natl. Acad. Sci. USA 91, 787-791, 1994.
39. PIERPAOLI, W. and YI, C.X. The involvement of pineal glanol and melatonin in immunity and aging. I. Thymus mediated, immunozeconstituting and antiviral activity of thyzotropin releasing hormone. J. Of Neuroimmunology 27, 99-109, 1990.
40. PRASAD, A.S., FITZGERALD, J.T., HESS, J.W., KAPLAN, J., PELEN, F., and DARDENNE, M. ZINC deficiency in elderly patients. Nutrition 9, 218-224, 1993.
41. PROVINCIALI, M., DI STEFANO, G., and FABRIS, N. Dose-dependent opposite effect of zinc on apoptosis in mouse thymocytes. Int. J. Immunopharmacol. 17, 735-744, 1995.
42. PROVINCIALI, M., DI STEFANO, G., BULIAN, D., TIBALDI, A., and FABRIS, N. Effect of melatonin and pineal grafting on thymocyte apoptosis in aging mice. MAD 90, 1-19, 1996.
43. REITER, R.J., TAN, D.X., POEGGELER, B., CHEN, L.D., and MENENDEZ-PELAEZ, A. MELATONIN, free radicals and cancer initiation. In: Advances in Pineal Research, Maestroni, G.J.M., Conti, A., and Reiter, R.R. (Editors), pp. 211-228, John Libbey, London, 1994.
44. ROTH, J.A., LAEBERLE, M.L., GRIER, D.L., HOPPER, J.G., SPIEGEL, H.E., and MACALLISTER, H.A. Improvement in clinical condition and thymic morphological features associated with growth treatment of immuno-deficient dwarf-dogs. Am. J. Vet. Res. 45, 1151-1155, 1984.
45. SAVINO, W. and DARDENNE, M. Thymic hormone-containing cells. IV. Immunohistologic evidence for the simultaneous presence of thymulin, thymopentin and thymosin α-1 in normal and pathological human thymuses. Eur. J. Immunol. 14, 987-992, 1984.
46. SEI, Y., YOSHIMOTO, K., MCINTYRE, SKOLNICK, P., and ARORA, P.K. Morphine-induced thymic hypoplasia is glucocorticoid dependent. J. Immunol. 146, 194-198, 1991.
47. SIMPSON, J.C., GRAY, E.S., MICHIE, W., and BECK, J.S. The influence of preoperative drug treatment on the extent of hyperplasia of the thymus in primary thyrotoxicosis. Clin. Exp. Immunol. 22, 249-253, 1975.
48. TOUITOU, Y., ARENDT, J, and PEVET, P. Melatonin and the Pineal Gland, pp. 379-382, Elsevier, Amsterdam, 1993.
49. TRAVAGLINI, P., MOCCHEGIANI, E., and TOGNI, E. Thymulin and zinc circulating level in patient with GH and PRL secreting pituitary adenomas. Int. J. Neurosci. 51, 269-271, 1990.
50. TRAVAGLINI, P., MORIONDO, P., TOGNI, E., VENEGONI, P., BOCCHICCHIO, D., FAGLIA, G., AMBROSO, G., PONTICELLI, C., MOCCHEGIANI, E., and FABRIS, N. Effect of oral zinc administration on prolactin and thymulin circulating level in uremic patients. J. Clin. Endocrinol. Metab. 68, 186-190, 1989.
51. WEIGENT, D.A. and BLALOCK, J.E. Association between the neuroendocrine and immune systems. Leukoc. Biol. 58, 137-150, 1995.
52. WILLIE, A.H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-557, 1980.