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Volumn 64, Issue 11, 1996, Pages 4456-4462

Cellular basis of decreased immune responses to pneumococcal vaccines in aged mice

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCUS VACCINE;

EID: 0029909142     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.11.4456-4462.1996     Document Type: Article
Times cited : (48)

References (62)
  • 1
    • 0025923467 scopus 로고
    • Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon. but not IL-2 by activated murine T cells
    • Araneo, B. A., T. Dowell, M. Diegel, and R. A. Dames. 1991. Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon. but not IL-2 by activated murine T cells. Blood 78:688-699.
    • (1991) Blood , vol.78 , pp. 688-699
    • Araneo, B.A.1    Dowell, T.2    Diegel, M.3    Dames, R.A.4
  • 2
    • 0001372661 scopus 로고
    • Pneumococcal bacteremia with especial reference to bacteremic pneumococcal pneumonia
    • Austrian, R., and J. Gold. 1964. Pneumococcal bacteremia with especial reference to bacteremic pneumococcal pneumonia. Ann. Intern. Med. 60:759-776.
    • (1964) Ann. Intern. Med. , vol.60 , pp. 759-776
    • Austrian, R.1    Gold, J.2
  • 3
    • 0026762857 scopus 로고
    • T cell regulation of the antibody response to bacterial polysaccharide antigens: An examination of some general characteristics and their implications
    • Baker, P. J. 1992. T cell regulation of the antibody response to bacterial polysaccharide antigens: an examination of some general characteristics and their implications. J. Infect. Dis. 165:S44-S48.
    • (1992) J. Infect. Dis. , vol.165
    • Baker, P.J.1
  • 5
    • 0022307664 scopus 로고
    • Human immune response to polysaccharide antigens: An analysis of bacterial vaccines in infants
    • Barett, D. J. 1985. Human immune response to polysaccharide antigens: an analysis of bacterial vaccines in infants. Adv. Pediatr. 32:139-158.
    • (1985) Adv. Pediatr. , vol.32 , pp. 139-158
    • Barett, D.J.1
  • 6
    • 0002847199 scopus 로고
    • Thymus independent antigens
    • E. C. Snow (ed.), Academic Press, New York
    • Bondada, S., and M. Garg. 1994. Thymus independent antigens, p. 343-370. In E. C. Snow (ed.), Handbook of B and T lymphocytes. Academic Press, New York.
    • (1994) Handbook of B and T Lymphocytes , pp. 343-370
    • Bondada, S.1    Garg, M.2
  • 7
    • 0020617087 scopus 로고
    • Activation of type III pneumococcal polysaccharide specific suppressor T cells in cyclophosphamide treated mice: Requirements for recognition of antigen and I-J determinants on antigen coupled to syngenic spleen cells
    • Braley-Mullen, H. 1983. Activation of type III pneumococcal polysaccharide specific suppressor T cells in cyclophosphamide treated mice: requirements for recognition of antigen and I-J determinants on antigen coupled to syngenic spleen cells. J. Immunol. 131:2190-2195.
    • (1983) J. Immunol. , vol.131 , pp. 2190-2195
    • Braley-Mullen, H.1
  • 8
    • 0025333508 scopus 로고
    • Distinct populations of antigen-presenting cells are required for activation of suppressor and contrasuppressor T cells by type III pneumococcal polysaccharide
    • Braley-Mullen, H. 1990. Distinct populations of antigen-presenting cells are required for activation of suppressor and contrasuppressor T cells by type III pneumococcal polysaccharide. Cell. Immunol. 128:528-541.
    • (1990) Cell. Immunol. , vol.128 , pp. 528-541
    • Braley-Mullen, H.1
  • 9
    • 0025992253 scopus 로고
    • Pneumococcal vaccine - Past, present, and future
    • Broome, C. V., and R. F. Breiman. 1991. Pneumococcal vaccine - past, present, and future. N. Engl. J. Med. 325:1506-1508.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1506-1508
    • Broome, C.V.1    Breiman, R.F.2
  • 10
    • 0003168669 scopus 로고
    • Immunization practices advisory committee (ACIP). Pneumococcal polysaccharide vaccine
    • Centers for Disease Control. 1989. Immunization practices advisory committee (ACIP). Pneumococcal polysaccharide vaccine. Morbid. Mortal. Weekly Rep. 38:64-76.
    • (1989) Morbid. Mortal. Weekly Rep. , vol.38 , pp. 64-76
  • 11
    • 10244252617 scopus 로고
    • Dissociation of the requirements for la and IL-1 during antigen presentation and oxidative mitogenesis
    • S. Reichard and M. Kozima (ed.), Alan R. Liss Inc., New York
    • Cohen, D. A., L. A. Smith, B. Subbarao, E. C. Snow, and A. M. Kaplan. 1985. Dissociation of the requirements for la and IL-1 during antigen presentation and oxidative mitogenesis, p. 177-191. In S. Reichard and M. Kozima (ed.), Macrophage biology. Alan R. Liss Inc., New York.
    • (1985) Macrophage Biology , pp. 177-191
    • Cohen, D.A.1    Smith, L.A.2    Subbarao, B.3    Snow, E.C.4    Kaplan, A.M.5
  • 12
    • 0000474770 scopus 로고
    • Prevention and reversal of some age associated changes in immunologic responses by supplemental dehdroepiandrosterone sulfate therapy
    • Daynes, R. A., and B. A. Araneo. 1992. Prevention and reversal of some age associated changes in immunologic responses by supplemental dehdroepiandrosterone sulfate therapy. Aging Immunol. Infect. Dis. 3:135-153.
    • (1992) Aging Immunol. Infect. Dis. , vol.3 , pp. 135-153
    • Daynes, R.A.1    Araneo, B.A.2
  • 13
    • 0025318862 scopus 로고
    • Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function
    • Daynes, R. A., B. A. Araneo, T. A. Dowell, K. Huang, and D. Dudley. 1990. Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function. J. Exp. Med. 171:979-996.
    • (1990) J. Exp. Med. , vol.171 , pp. 979-996
    • Daynes, R.A.1    Araneo, B.A.2    Dowell, T.A.3    Huang, K.4    Dudley, D.5
  • 14
    • 0027162602 scopus 로고
    • Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative
    • Daynes, R. A., B. A. Araneo, W. B. Ershler, C. Maloney, G. Z. Li, and S. Y. Ryu. 1993. Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative. J. Immunol. 150:5219-5230.
    • (1993) J. Immunol. , vol.150 , pp. 5219-5230
    • Daynes, R.A.1    Araneo, B.A.2    Ershler, W.B.3    Maloney, C.4    Li, G.Z.5    Ryu, S.Y.6
  • 15
    • 0020681409 scopus 로고
    • A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens
    • Endres, R. O., E. Kushnir, J. W. Kappler, P. Marrack, and S. C. Kinsky. 1983. A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens. J. Immunol. 130:781.
    • (1983) J. Immunol. , vol.130 , pp. 781
    • Endres, R.O.1    Kushnir, E.2    Kappler, J.W.3    Marrack, P.4    Kinsky, S.C.5
  • 16
    • 0027194911 scopus 로고
    • Reversal of age-associated decline in immune response to Pnu-Imune vaccine by supplementation with the steroid hormone dehydroepiandrosterone
    • Garg, M., and S. Bondada. 1993. Reversal of age-associated decline in immune response to Pnu-Imune vaccine by supplementation with the steroid hormone dehydroepiandrosterone. Infect. Immun. 61:2238-2241.
    • (1993) Infect. Immun. , vol.61 , pp. 2238-2241
    • Garg, M.1    Bondada, S.2
  • 17
    • 0028204374 scopus 로고
    • Cellular basis of differential responsiveness of lymph nodes and spleen to 23-valent Pnu-Imune vaccine
    • Garg, M., A. M. Kaplan, and S. Bondada. 1994. Cellular basis of differential responsiveness of lymph nodes and spleen to 23-valent Pnu-Imune vaccine. J. Immunol. 152:1589-1596.
    • (1994) J. Immunol. , vol.152 , pp. 1589-1596
    • Garg, M.1    Kaplan, A.M.2    Bondada, S.3
  • 18
    • 0026773798 scopus 로고
    • Immune responses of systemic and mucosal lymphoid organs to Pnu-Imune vaccine as a function of age and the efficacy of monophosphoryl lipid A as an adjuvant
    • Garg, M., and B. Subbarao. 1992. Immune responses of systemic and mucosal lymphoid organs to Pnu-Imune vaccine as a function of age and the efficacy of monophosphoryl lipid A as an adjuvant. Infect. Immun. 60:2329-2336.
    • (1992) Infect. Immun. , vol.60 , pp. 2329-2336
    • Garg, M.1    Subbarao, B.2
  • 19
    • 0025248038 scopus 로고
    • Th1 and Th2 clones differ in their response to a tolerogenic signal
    • Gilbert, K. M., K. D. Hoang, and W. O. Weigle. 1990. Th1 and Th2 clones differ in their response to a tolerogenic signal. J. Immunol. 144:2063-2071.
    • (1990) J. Immunol. , vol.144 , pp. 2063-2071
    • Gilbert, K.M.1    Hoang, K.D.2    Weigle, W.O.3
  • 20
    • 0024578839 scopus 로고
    • Aspects of pneumococcal infection including bacterial virulence, host response and vaccination
    • Gillespie, S. H. 1989. Aspects of pneumococcal infection including bacterial virulence, host response and vaccination. J. Med. Microbiol. 28:237-248.
    • (1989) J. Med. Microbiol. , vol.28 , pp. 237-248
    • Gillespie, S.H.1
  • 21
    • 0017167094 scopus 로고
    • Immunological studies of aging II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice
    • Goidl, E. A., J. B. Innes, and M. E. Weksler. 1976. Immunological studies of aging II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice. J. Exp. Med. 144:1037-1048.
    • (1976) J. Exp. Med. , vol.144 , pp. 1037-1048
    • Goidl, E.A.1    Innes, J.B.2    Weksler, M.E.3
  • 22
    • 0025315253 scopus 로고
    • Primary antibody responses to thymus-independent antigens in the lungs and hilar lymph nodes of mice
    • Goud, S. N., A. M. Kaplan, and B. Subbarao. 1990. Primary antibody responses to thymus-independent antigens in the lungs and hilar lymph nodes of mice. Infect. Immun. 58:2035-2041.
    • (1990) Infect. Immun. , vol.58 , pp. 2035-2041
    • Goud, S.N.1    Kaplan, A.M.2    Subbarao, B.3
  • 23
    • 0025167734 scopus 로고
    • Antibody responses to thymic independent antigens in the peripheral and mesenteric lymph nodes of mice
    • Goud, S. N., A. M. Kaplan, and B. Subbarao. 1990. Antibody responses to thymic independent antigens in the peripheral and mesenteric lymph nodes of mice. Reg. Immunol. 3:1-7.
    • (1990) Reg. Immunol. , vol.3 , pp. 1-7
    • Goud, S.N.1    Kaplan, A.M.2    Subbarao, B.3
  • 24
    • 0026440899 scopus 로고
    • Priming of peripheral lymph node B cells with TNP-Ficoll: Role of lymphokines in B cell differentiation
    • Goud, S. N., A. M. Kaplan, and B. Subbarao. 1992. Priming of peripheral lymph node B cells with TNP-Ficoll: role of lymphokines in B cell differentiation. Cell. Immunol. 144:407-416.
    • (1992) Cell. Immunol. , vol.144 , pp. 407-416
    • Goud, S.N.1    Kaplan, A.M.2    Subbarao, B.3
  • 25
    • 0023889594 scopus 로고
    • Differential responses of B-cells from the spleen and lymph node to TNP-Ficoll
    • Goud, S. N., N. Muthusamy, and B. Subbarao. 1988. Differential responses of B-cells from the spleen and lymph node to TNP-Ficoll. J. Immunol. 140:2925-2930.
    • (1988) J. Immunol. , vol.140 , pp. 2925-2930
    • Goud, S.N.1    Muthusamy, N.2    Subbarao, B.3
  • 26
    • 0021843808 scopus 로고
    • Influence of age on the production and regulation of interleukin-1 in mice
    • Inamizu, T., M. P. Chang, and T. Makinodan. 1985. Influence of age on the production and regulation of interleukin-1 in mice. Cell. Immunol. 55:447-455.
    • (1985) Cell. Immunol. , vol.55 , pp. 447-455
    • Inamizu, T.1    Chang, M.P.2    Makinodan, T.3
  • 27
    • 0023813224 scopus 로고
    • The clonotype repertoire of B cell subpopulations
    • Klinman, N. R., and P.-J. Linton. 1988. The clonotype repertoire of B cell subpopulations. Adv. Immunol. 42:1-93.
    • (1988) Adv. Immunol. , vol.42 , pp. 1-93
    • Klinman, N.R.1    Linton, P.-J.2
  • 28
    • 0020051596 scopus 로고
    • Cause of death in very old people
    • Kohn, R. P. 1982. Cause of death in very old people. JAMA 247:2793-2797.
    • (1982) JAMA , vol.247 , pp. 2793-2797
    • Kohn, R.P.1
  • 29
    • 1842304486 scopus 로고
    • B-lymphocyte responses to trinitrophenyl-conjugated Ficoll: Requirement for T lymphocytes and 1a-bearing adherent cells
    • Letvin, N. L., B. Benacerraf, and R. L. Germain. 1981. B-lymphocyte responses to trinitrophenyl-conjugated Ficoll: requirement for T lymphocytes and 1a-bearing adherent cells. Proc. Natl. Acad. Sci. USA 78:5113.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 5113
    • Letvin, N.L.1    Benacerraf, B.2    Germain, R.L.3
  • 31
    • 0016235979 scopus 로고
    • Separation of mouse spleen cells by passage through columns of Sephadex G-10
    • Ly, I. A., and R. I. Mishell. 1974. Separation of mouse spleen cells by passage through columns of Sephadex G-10. J. Immunol. Methods 5:239.
    • (1974) J. Immunol. Methods , vol.5 , pp. 239
    • Ly, I.A.1    Mishell, R.I.2
  • 32
    • 0024536869 scopus 로고
    • Kinetics in peritoneal cell populations following acute inflammation
    • Melnicoff, M. J., P. K. Horan, and P. S. Morahan. 1989. Kinetics in peritoneal cell populations following acute inflammation. Cell. Immunol. 118:178-191.
    • (1989) Cell. Immunol. , vol.118 , pp. 178-191
    • Melnicoff, M.J.1    Horan, P.K.2    Morahan, P.S.3
  • 33
    • 0028268894 scopus 로고
    • Aging and immune function: Cellular and biochemical analyses
    • Miller, R. A. 1994. Aging and immune function: cellular and biochemical analyses. Exp. Gerontol. 29:21-35.
    • (1994) Exp. Gerontol. , vol.29 , pp. 21-35
    • Miller, R.A.1
  • 34
    • 0020624716 scopus 로고
    • T cell dependence and factor reconstitution of in vitro antibody responses to TNP-B. abortus and TNP-Ficoll: Restoration of depleted response with chrormitographed fractions of a T cell-derived factor
    • Mond, J. J., J. Farrar, W. E. Paul, J. Fuller-Farrar, M. Schaefer, and M. Howard. 1983. T cell dependence and factor reconstitution of in vitro antibody responses to TNP-B. abortus and TNP-Ficoll: restoration of depleted response with chrormitographed fractions of a T cell-derived factor. J. Immunol. 131:633.
    • (1983) J. Immunol. , vol.131 , pp. 633
    • Mond, J.J.1    Farrar, J.2    Paul, W.E.3    Fuller-Farrar, J.4    Schaefer, M.5    Howard, M.6
  • 36
    • 0019512039 scopus 로고
    • Primary in vitro antibody response by purified murine B lymphocytes in serum-free defined medium
    • Mosier, D. E. 1981. Primary in vitro antibody response by purified murine B lymphocytes in serum-free defined medium. J. Immunol. 127:1490-1494.
    • (1981) J. Immunol. , vol.127 , pp. 1490-1494
    • Mosier, D.E.1
  • 37
    • 0024598411 scopus 로고
    • A specific defect in the proliferative capacity of B cells from old mice stimulated with autoreactive T cells
    • Nagarkatti, P. S., A. Seth, M. Nagarkatti, N. Muthusamy, B. Rychlik, and B. Subbarao. 1989. A specific defect in the proliferative capacity of B cells from old mice stimulated with autoreactive T cells. Cell. Immunol. 120:102-113.
    • (1989) Cell. Immunol. , vol.120 , pp. 102-113
    • Nagarkatti, P.S.1    Seth, A.2    Nagarkatti, M.3    Muthusamy, N.4    Rychlik, B.5    Subbarao, B.6
  • 38
    • 0026760182 scopus 로고
    • The crisis in antibiotic resistance
    • Neu, H. C. 1992. The crisis in antibiotic resistance. Science 257:1064-1073.
    • (1992) Science , vol.257 , pp. 1064-1073
    • Neu, H.C.1
  • 40
    • 0025346495 scopus 로고
    • Diminished calcium signal generation in subsets of T lymphocytes that predominate in old mice
    • Philosophe, B., and R. A. Miller. 1990. Diminished calcium signal generation in subsets of T lymphocytes that predominate in old mice. J. Gerontol. 45:B87-B93.
    • (1990) J. Gerontol. , vol.45
    • Philosophe, B.1    Miller, R.A.2
  • 41
    • 0021336856 scopus 로고
    • A reappraisal of "T-independent" antigens. I. Effect of lymphokines on the response of single adult hapten-specific B lymphocytes
    • Pike, B. L., and G. J. V. Nossal. 1984. A reappraisal of "T-independent" antigens. I. Effect of lymphokines on the response of single adult hapten-specific B lymphocytes. J. Immunol. 132:1687.
    • (1984) J. Immunol. , vol.132 , pp. 1687
    • Pike, B.L.1    Nossal, G.J.V.2
  • 42
    • 0023934179 scopus 로고
    • Frequencies of IL-2- and IL-4-secreting T cells in naive and antigen-stimulated lymphocyte populations
    • Powers, G. D., A. K. Abbas, and R. A, Miller. 1988. Frequencies of IL-2- and IL-4-secreting T cells in naive and antigen-stimulated lymphocyte populations. J. Immunol. 140:3352-3357.
    • (1988) J. Immunol. , vol.140 , pp. 3352-3357
    • Powers, G.D.1    Abbas, A.K.2    Miller, R.A.3
  • 43
    • 0002275822 scopus 로고
    • Modulation of humoral and cell mediated immune responses by a structurally established nontoxic lipid A
    • A. Szentivanji and H. Friedman (ed.), Plenum Press, New York
    • Ribi, E., J. L. Cantrell, K. Takayama, H. O. Ribi, K. R. Myers, and N. Qureshi. 1986. Modulation of humoral and cell mediated immune responses by a structurally established nontoxic lipid A, p. 407-420. In A. Szentivanji and H. Friedman (ed.), Immunobiology and immunopharmacology of bacterial endotoxins. Plenum Press, New York.
    • (1986) Immunobiology and Immunopharmacology of Bacterial Endotoxins , pp. 407-420
    • Ribi, E.1    Cantrell, J.L.2    Takayama, K.3    Ribi, H.O.4    Myers, K.R.5    Qureshi, N.6
  • 44
    • 0023638874 scopus 로고
    • Immune response of elderly adults to pneumococcus: Variation by age, sex, and functional impairment
    • Roghmann, K. J., P. A. Tabloski, D. W. Bentley, and G. Schiffman. 1987. Immune response of elderly adults to pneumococcus: variation by age, sex, and functional impairment. J. Gerontol. 42:265-270.
    • (1987) J. Gerontol. , vol.42 , pp. 265-270
    • Roghmann, K.J.1    Tabloski, P.A.2    Bentley, D.W.3    Schiffman, G.4
  • 45
    • 0026709728 scopus 로고
    • Synthesis of a conjugate vaccine composed of pneumococcal type 14 capsular polysaccharide bound to pertussis toxin
    • Schneerson, R., L. Levi, J. B. Robbing, D. M. Bryla, G. Schiffman, and T. Lagegard. 1992. Synthesis of a conjugate vaccine composed of pneumococcal type 14 capsular polysaccharide bound to pertussis toxin. Infect. Immun. 60:3528-3532.
    • (1992) Infect. Immun. , vol.60 , pp. 3528-3532
    • Schneerson, R.1    Levi, L.2    Robbing, J.B.3    Bryla, D.M.4    Schiffman, G.5    Lagegard, T.6
  • 46
    • 0020697050 scopus 로고
    • Infectious disease in elderly
    • Schneider, E. L. 1983. Infectious disease in elderly. Am. Int. Med. 98:395.
    • (1983) Am. Int. Med. , vol.98 , pp. 395
    • Schneider, E.L.1
  • 47
    • 0025355495 scopus 로고
    • Macrophages but not B cells from aged mice are defective in stimulating autoreactive T cells in vitro
    • Seth, A., M. Nagarkatti, P. S. Nagarkatti, B. Subbarao, and V. Udhayakumar. 1990. Macrophages but not B cells from aged mice are defective in stimulating autoreactive T cells in vitro. Mech. Ageing Dev. 52:107-124.
    • (1990) Mech. Ageing Dev. , vol.52 , pp. 107-124
    • Seth, A.1    Nagarkatti, M.2    Nagarkatti, P.S.3    Subbarao, B.4    Udhayakumar, V.5
  • 49
    • 0021751887 scopus 로고
    • Streptococcus pneumoniae infections and bacteremia in patients with acquired immune deficiency syndrome, with a report of pneumococcal vaccine failure
    • Simberkoff, M. S., E. L. Sadr, G. Schiffman, and J. J. Rahal. 1984. Streptococcus pneumoniae infections and bacteremia in patients with acquired immune deficiency syndrome, with a report of pneumococcal vaccine failure. Am. Rev, Respir. Dis. 130:1174-1176.
    • (1984) Am. Rev, Respir. Dis. , vol.130 , pp. 1174-1176
    • Simberkoff, M.S.1    Sadr, E.L.2    Schiffman, G.3    Rahal, J.J.4
  • 51
    • 0023215419 scopus 로고
    • Functions of accessory cells in B cell responses to thymus-independent antigens
    • Sinha, A. A., C. Guidos, K.-C. Lee, and E. Diener. 1987. Functions of accessory cells in B cell responses to thymus-independent antigens. J. Immunol. 138:4143-4149.
    • (1987) J. Immunol. , vol.138 , pp. 4143-4149
    • Sinha, A.A.1    Guidos, C.2    Lee, K.-C.3    Diener, E.4
  • 52
    • 0017229486 scopus 로고
    • The effects of age on the immune response to type III pneumococcal polysaccharide (SIII) and bacterial lipopolysaccharide (LPS) in BALB/c, SJL/J and C3H mice
    • Smith, A. M. 1975. The effects of age on the immune response to type III pneumococcal polysaccharide (SIII) and bacterial lipopolysaccharide (LPS) in BALB/c, SJL/J and C3H mice. J. Immunol. 116:469-474.
    • (1975) J. Immunol. , vol.116 , pp. 469-474
    • Smith, A.M.1
  • 53
    • 0020633193 scopus 로고
    • Induction of B lymphocyte proliferation without antibody secretion by monoclonal anti-Lyb2 antibody
    • Subbarao, B., and D. E. Mosier. 1983. Induction of B lymphocyte proliferation without antibody secretion by monoclonal anti-Lyb2 antibody. J. Immunol. 130:2033-2037.
    • (1983) J. Immunol. , vol.130 , pp. 2033-2037
    • Subbarao, B.1    Mosier, D.E.2
  • 54
    • 10244262703 scopus 로고
    • Contribution of intrinsic defects in B cells to age associated decrease in T dependent antibody responses
    • Subbarao, B., B. R. Rychlik, J. Baker, and E. W. Williams. 1990. Contribution of intrinsic defects in B cells to age associated decrease in T dependent antibody responses. Aging Immunol. Infect. Dis. 2:143-151.
    • (1990) Aging Immunol. Infect. Dis. , vol.2 , pp. 143-151
    • Subbarao, B.1    Rychlik, B.R.2    Baker, J.3    Williams, E.W.4
  • 55
    • 0021281152 scopus 로고
    • Characteristics of amplifier T cells involved in the antibody response to the capsular polysaccharide of type III Streptococcus pneumoniae
    • Taylor, C. E., P. W. Stashak, G. Chiang, W. M. Leiserson, G. Caldes, B. Prescott, and P. J. Baker. 1984. Characteristics of amplifier T cells involved in the antibody response to the capsular polysaccharide of type III Streptococcus pneumoniae. J. Immunol. 132:3103-3108.
    • (1984) J. Immunol. , vol.132 , pp. 3103-3108
    • Taylor, C.E.1    Stashak, P.W.2    Chiang, G.3    Leiserson, W.M.4    Caldes, G.5    Prescott, B.6    Baker, P.J.7
  • 57
    • 0024325071 scopus 로고
    • The cellular and subcellular bases of immunosenescence
    • Thoman, M. L., and W. O. Weigle. 1989. The cellular and subcellular bases of immunosenescence. Adv. Immunol. 44:221-261.
    • (1989) Adv. Immunol. , vol.44 , pp. 221-261
    • Thoman, M.L.1    Weigle, W.O.2
  • 58
    • 0023701481 scopus 로고
    • Physiology of murine B lymphocytes. I. Life-spans of anti-μ and haptenated Ficoll (thymus-independent antigen)-reactive B cells
    • Udhayakumar, V., S. N. Goud, and B. Subbarao. 1988. Physiology of murine B lymphocytes. I. Life-spans of anti-μ and haptenated Ficoll (thymus-independent antigen)-reactive B cells. Eur. J. Immunol. 18:1593.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1593
    • Udhayakumar, V.1    Goud, S.N.2    Subbarao, B.3
  • 59
    • 0020627375 scopus 로고
    • Bacterial pneumonia in the elderly
    • Verghese, A., and S. L. Berk. 1992. Bacterial pneumonia in the elderly. Medicine (Baltimore) 62:271-285.
    • (1992) Medicine (Baltimore) , vol.62 , pp. 271-285
    • Verghese, A.1    Berk, S.L.2
  • 60
    • 0023836268 scopus 로고
    • The effect of aging on the induction of tolerance in a subpopulation of B lymphocytes
    • Weigle, W. O., M. L. Thoman, and M. G. Goodman. 1988. The effect of aging on the induction of tolerance in a subpopulation of B lymphocytes. Cell. Immunol. 111:253-257.
    • (1988) Cell. Immunol. , vol.111 , pp. 253-257
    • Weigle, W.O.1    Thoman, M.L.2    Goodman, M.G.3
  • 61
    • 0023721896 scopus 로고
    • Age-related changes in the capability of the bone marrow to generate B cells
    • Zharhary, D. 1988. Age-related changes in the capability of the bone marrow to generate B cells. J. Immunol. 141:1863-1869.
    • (1988) J. Immunol. , vol.141 , pp. 1863-1869
    • Zharhary, D.1
  • 62
    • 0020614457 scopus 로고
    • Antigen responsiveness of the mature and generative B cell population of aged mice
    • Zharhary, D., and N. R. Klinman. 1983. Antigen responsiveness of the mature and generative B cell population of aged mice. J. Exp. Med. 157:1300-1308.
    • (1983) J. Exp. Med. , vol.157 , pp. 1300-1308
    • Zharhary, D.1    Klinman, N.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.