Shedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line

Japanese Journal of Cancer Research

Volumn 90, Issue 9, 1999, Pages 942-950

  Harayama, Takeshi ^a   Ohuchi, Eiko ^b   Aoki, Takanori ^b   Sato, Hiroshi ^a   Seiki, Motoharu ^c   Okada, Yasunori ^d  

^a KANAZAWA UNIVERSITY   (Japan)

^b FUJI CHEMICAL INDUSTRIES LTD   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KEIO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Concanavalin A; Invasion and metastasis; Membrane type matrix metalloproteinase; Shedding

Indexed keywords

CELL SURFACE PROTEIN; COLLAGENASE; EDETIC ACID; GELATINASE A; MEMBRANE ENZYME; MESSENGER RNA; METALLOPROTEINASE INHIBITOR; PHENANTHROLINE;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CELL LYSATE; CELL VIABILITY; CONTROLLED STUDY; ENZYME IMMUNOASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOLECULAR WEIGHT; MULTIGENE FAMILY; NORTHERN BLOTTING; PRIORITY JOURNAL;

EID: 0032707133     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1999.tb00839.x     Document Type: Article

References (43)

1. Stetler-Stevenson, W. A. G., Aznavoorian, S. and Liotta, L. A. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol., 9, 541-573 (1993).
2. Okada, Y. Proteinases and matrix degradation. In "Textbook of Rheumatology," 6th Ed., ed. W. N. Kelley, E. D. Harris, Jr., S. Ruddy and C. B. Sledge (1999). W. B. Saunders Co., Philadelphia, in press.
3. Nagase, H. Activation mechanisms of matrix metalloproteinases. Biol. Chem., 378, 151-160 (1997).
4. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E. and Seiki. M. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature, 370, 61-65 (1994).
5. Tokuraku, M., Sato, H., Murakami, S., Okada, Y., Watanabe, Y. and Seiki, M. Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int. J. Cancer, 64, 355-359 (1995).
6. Ueno, H., Nakamura, H., Inoue, M., Imai, K., Noguchi, M., Sato, H., Seiki, M. and Okada, Y. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res., 57, 2055-2060 (1997).
7. Nomura, H., Sato, H., Seiki, M., Mai, M. and Okada, Y. Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res., 55, 3263-3266 (1995).
8. Nakamura, H., Ueno, H., Yamashita, K., Shimada, T., Yamamoto, E., Noguchi, M., Fujimoto, N., Sato, H., Seiki, M. and Okada, Y. Enhanced production and activation of progelatinase A mediated membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas. Cancer Res., 59, 467-473 (1999).
9. Ohuchi, E., Imai, K., Fujii, Y., Sato, H., Seiki, M. and Okada, Y. Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J. Biol. Chem., 272, 2446-2451 (1997).
10. Atkinson, S. J., Crabbe, T., Cowell, S., Ward, R. V., Butler, M. J., Sato, H., Seiki, M., Reynolds, J. J. and Murphy, G. Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membrane. J. Biol. Chem., 270, 30479-30485 (1995).
11. Lewalle, J. M., Munaut, C., Pichot, B., Cataldo, D., Baramova, E. and Foidart, J. M. Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells. J. Cell. Physiol., 165, 475-483 (1995).
12. Lohi, J. and Keski-Oja, J. Calcium ionophores decrease pericellular gelatinolytic activity via inhibition of 92-kDa gelatinase expression and decrease of 72-kDa gelatinase activation. J. Biol. Chem., 270, 17602-17609 (1995).
13. Lohi, J., Lehti, K., Westermarck, J., Kähäri, V. M. and Keski-Oja, J. Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur. J. Biochem., 239, 239-247 (1996).
14. Okada, A., Bellocq, J. P., Rouyer, N., Chenars, M. P., Rio, M. C., Chanbon, P. and Basset, P. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc. Natl. Acad. Sci. USA, 92, 2730-2734 (1995).
15. Imai, K., Ohta, S., Matsumoto, T., Fujimoto, N., Sato, H., Seiki, M. and Okada, Y. Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage. Am. J. Pathol., 151, 245-256 (1997).
16. Mohler, K. M., Sleath, P. R., Fitzner, J. N., Cerretti, D. P., Alderson, M., Kerwar, S. S., Torrance, D. S., Otten-Evans, C., Greenstreet, T., Weerawarna, K., Kronheim, S. R., Petersen, M., Gerhart, M., Kozlosky, C. J., March, C. J. and Black, R. A. Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing. Nature, 370, 218-220 (1994).
17. Roberts, S. B., Ripellino, J. A., Ingalls, K. M., Robakis, N. K. and Felsenstein, K. M. Non-amyloidogenic cleavage of the β-amyloid precursor protein by integral membrane metalloendopeptidase. J. Biol. Chem., 269, 3111-3116 (1994).
18. Ramchandran, R. and Sen, I. Cleavage processing of angiotensin-converting enzyme by a membrane-associated metalloprotease. Biochemistry, 34, 12645-12652 (1995).
19. Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T. K., Rose-John, S. and Massague, J. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors. J. Biol. Chem., 271, 11376-11382 (1996).
20. Mullberg, J., Durie, F. H., Otten-Evans, C., Alderson, M. R., Rose-John, S., Cosman, D., Black, R. A. and Mohler, K. M. A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor. J. Immunol., 155, 5198-5205 (1995).
21. Imai, K., Ohuchi, E., Aoki, T., Nomura, H., Fujii, Y., Sato, H., Seiki, M. and Okada, Y. Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2. Cancer Res., 56, 2707-2710 (1996).
22. Hayakawa, T., Yamashita, K., Ohuchi, E. and Shinagawa, A. Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). J. Cell Sci., 107, 2373-2379 (1994).
23. Davies, B., Miles, D. W., Happerfield, D. C., Naylor, M. S., Bobrow, L. G., Rubens, R. D. and Baldwill, F. R. Activity of type IV collagenases in benign and malignant breast disease. Br. J. Cancer, 67, 1126-1131 (1993).
24. Tanaka, M., Sato, H., Takino, T., Iwata, K., Inoue, M. and Seiki, M. Identification of mouse MT2-MMP gene from a lung cDNA library and identification of its product. FEBS Lett., 402, 219-222 (1997).
25. Ohuchi, E., Azumano, I., Yoshida, S., Iwata, K. and Okada, Y. A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 7 (matrilysin) using monoclonal antibodies. Clin. Chim. Acta, 244, 181-198 (1996).
26. Hooper, N. M., Karran, E. H. and Turner, A. J. Membrane protein secretases. Biochem. J., 321, 265-279 (1997).
27. Ehlers, M. R. W. and Riordan, J. F. Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins. Biochemistry, 30, 10065-10074 (1991).
28. Rose-John, S. and Heinrich, P. C. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem. J., 300, 281-290 (1994).
29. Gearing, A. J. H., Beckett, P., Christodoulou, M., Churchill, M., Clements, J., Davidson, A. H., Drummond, A. H., Galloway, W. A., Gilbert, R., Gordon, J. L., Leber, T. M., Mangan, M., Miller, K., Nayee, P., Owen, K., Patel, S., Thomas, W., Wells, G., Wood, L. M. and Woolley, K. Processing of tumour necrosis factor-α precursor by metalloproteinases. Nature, 370, 555-557 (1994).
30. McGeehan, K. G. M., Becherer, J. D., Bast, R. C., Boyer, C. M., Champion, B., Connolly, K. M., Conway, J. G., Furdon, P., Karp, S., Kidao, S., McElroy, A. B., Nichols, J., Pryzwansky, K. M., Schoenen, F., Sekut, L., Truesdale, A., Verghese, M., Warner, J. and Ways, J. P. Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor. Nature, 370, 558-561 (1994).
31. Pandiella, A. and Massague, J. Cleavage of the membrane precursor for transforming growth factor α is a regulated process. Proc. Natl. Acad. Sci. USA, 88, 1726-1730 (1991).
32. Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. P., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S., Nelson, N., Boiani, N., Schooley, K. A., Gerhart, M., Davis, R., Fitzner, J. N., Johnson, R. S., Paxton, C. J., March, C. J. and Cerretti, D. P. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells. Nature, 385, 729-733 (1997).
33. Moss, M. L., Jin, S.-L. C., Milla, M. E., Burkhart, W., Carter, H. L., Chen, Wen-Ji, Clay, W. C., Didsbury, J. R., Hassler, D., Hoffman, C. R., Kost, T. A., Lambert, M. H., Leesnitzer, M. A., McCauley, P., McGeehan, G., Mitchell, J., Moyer, M., Panel, G., Rocque, W., Overton, L. K., Schoenen, F., Seaton, T., Su, J., Warner, J., Willard, D. and Becherer, J. D. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α. Nature, 385, 733-736 (1997).
34. Kulkarni, G. V. and McCulloch, C. A. G. Concanavalin A induced apoptosis in fibroblasts: the role of cell surface carbohydrates in lectin mediated cytotoxicity. J. Cell. Physiol., 165, 119-133 (1995).
35. Schwartz, L. M. and Osborne, B. A. Programmed cell death, apoptosis and killer genes. Immunol. Today, 14, 582-590 (1993).
36. 2+ concentration. Arch. Biochem. Biophys., 269, 365-370 (1989).
37. 2+ concentration and DNA fragmentation. Cancer Res., 52, 1342-1346 (1992).
38. Kelley, L. L., Koury, M. J. and Bondurant, M. C. Regulation of programmed cell death in erythroid progenitor cells by erythropoietin: effects of calcium and of protein and RNA synthesis. J. Cell. Physiol., 151, 487-496 (1992).
39. Kvanta, A., Kontny, E., Jondal, M., Okret, S. and Fredholm, B. B. Mitogen stimulation of T-cells increases c-Fos and c-Jun protein levels, AP-1 binding and AP-1 transcriptional activity. Cell. Signal., 4, 275-286 (1992).
40. Yu, M., Sato. H., Seiki, M. and Thompson, E. W. Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells. Cancer Res., 55, 3272-3277 (1995).
41. Brown, S. B., Kluck, R. M. and Ellem, K. A. O. Loss and shedding of surface markers from the leukemic myeloid monocytic line THP-1 induced to undergo apoptosis. J. Cell. Biochem., 60, 246-259 (1996).
42. Galli, C., Piccini, A., Ciotti, M. T., Castellani, L., Calissano, P., Zaccheo, D. and Tabaton, M. Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis. Proc. Natl. Acad. Sci. USA, 95, 1247-1252 (1998).
43. Kinoshita, T., Sato, H., Okada, A., Ohuchi, E., Imai, K., Okada, Y. and Seiki, M. TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J. Biol. Chem., 273, 16098-16103 (1998).