Expression of matrix metalloproteinases during rat skin wound healing: Evidence that membrane type-1 matrix metalloproteinase is a stromal activator of pro-gelatinase A

Journal of Cell Biology

Volumn 137, Issue 1, 1997, Pages 67-77

  Okada, Akiko ^a,c   Tomasetto, Catherine ^a   Lutz, Yves ^a   Bellocq, Jean Pierre ^b   Rio, Marie Christine ^a   Basset, Paul ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b HÔPITAL DE HAUTEPIERRE   (France)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; STROMELYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINE; DNA LIBRARY; GENE EXPRESSION; GENETIC SCREENING; GENETIC TRANSFECTION; IMMUNOBLOTTING; MOLECULAR CLONING; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT; RNA ANALYSIS; WOUND HEALING;

ANIMALS; BLOTTING, NORTHERN; CLONING, MOLECULAR; COLLAGENASES; COS CELLS; DNA, COMPLEMENTARY; ENZYME ACTIVATION; ENZYME PRECURSORS; FEMALE; FIBROBLASTS; GELATINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE LIBRARY; GRANULATION TISSUE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PROTEASE INHIBITORS; PROTEINS; RATS; RATS, WISTAR; SEQUENCE HOMOLOGY, AMINO ACID; SKIN; SPECIFIC PATHOGEN-FREE ORGANISMS; STROMAL CELLS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASE-3; WOUND HEALING;

EID: 0030904444     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.137.1.67     Document Type: Article

References (40)

1. Atkinson, S.J., T. Crabbe, S. Cowell, R.V. Ward, M.J. Butler, H. Sato, M. Seiki, J.J. Reynolds, and G. Murphy. 1995. Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes. J. Biol. Chem. 270:30479-30485.
2. Birkedal-Hansen, H. 1995. Proteolytic remodeling of extracellular matrix. Curr. Opin. Cell Biol. 7:728-735.
3. Breathnach, R., L.M. Matrisian, M.C. Gesnel, A. Staub, and P. Leroy. 1987. Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene. Nucleic Acids Res. 15:1139-1151.
4. Brooks, P.C., S. Strömblad, L.C. Sanders, T.L. von Schalscha, R.T. Aimes, W.G. Stetler-Stevenson, J.P. Quigley, and D.A. Cheresh. 1996. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell. 85:683-693.
5. Carmeliet, P., and D. Collen. 1995. Gene targeting and gene transfer studies of the plasminogen/plasmin system: implications in thrombosis, hemostasis, neointima formation, and atherosclerosis. FASEB (Fed. Am. Soc. Exp. Biol.) J. 9:934-938.
6. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. Anal. Biochem. 162:156-159.
7. Fisher, C., S. Gilbertson-Beadling, E.A. Powers, G. Petzold, R. Poorman, and M.A. Mitchell. 1994. Interstitial collagenase is required for angiogenesis in vitro. Dev. Biol. 162:499-510.
8. Gailit, J., and R.A.F. Clark. 1994. Wound repair in the context of extracellular matrix. Curr. Opin. Cell Biol. 6:717-725.
9. Heppner, K.J., L.M. Matrisian, R.A. Jensen, and W.H. Rodgers. 1996. Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Am. J. Pathol. 149:273-282.
10. Kinoh, H., H. Sato, Y. Tsunezuka, T. Takino, A. Kawashima, Y. Okada, and M. Seiki. 1996. MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis. J. Cell. Sci. 109:953-959.
11. Knäuper, V., C. López-Otin, B. Smith, G. Knight, and G. Murphy. 1996. Biochemical characterization of human collagenase-3. J. Biol. Chem. 271:1544-1550.
12. Marti, H.P., L. McNeil, M. Davies, J. Martin, and D.H. Lovett. 1993. Homology cloning of rat 72 kDa type IV collagenase: cytokine and second-messenger inducibility in glomerular mesangial cells. Biochem. J. 291:441-446.
13. Masiakowski, P., R. Breathnach, J. Bloch, F. Gannon, A. Krust, and P. Chambon. 1982. Cloning of cDN A sequence of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res. 10:7895-7903.
14. Matrisian, L.M., N. Glaichenhaus, M.C. Gesnel, and R. Breathnach. 1985. Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts. EMBO (Eur. Mol. Biol. Organ.) J. 4:1435-1440.
15. Matrisian, L.M., P. Leroy, C. Ruhlmann, M.C. Gesnel, and R. Breathnach. 1986a. Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts. Mol. Cell Biol. 6:1679-1686.
16. Matrisian, L.M., G.T. Bowden, P. Krieg, G. Fürstenberger, J.P. Briand, P. Leroy, and R. Breathnach. 1986b. The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc. Natl. Acad. Sci. USA. 83:9413-9417.
17. Nomura, H., H. Sato, M. Seiki, M. Mai, and Y. Okada. 1995. Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res. 55:3263-3266.
18. Ogata, Y., J.J. Enghild, and H. Nagase. 1992. Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9. J. Biol. Chem. 267:3581-3584.
19. Okada, A., J.M. Garnier, S. Vicaire, and P. Basset. 1994. Cloning of the cDNA encoding rat tissue inhibitor of metalloproteinase 1 (TIMP-1), amino acid comparison with other TIMPs, and gene expression in rat tissues. Gene (Amst.). 147:301-302.
20. Okada, A., J.P. Bellocq, N. Rouyer, M.P. Chenard, M.C. Rio, P. Chambon, and P. Basset. 1995a. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc. Natl. Acad. Sci. USA. 92:2730-2734.
21. Okada, A., M. Santavicca, and P. Basset. 1995b. The cDNA cloning and expression of the gene encoding rat gelatinase B. Gene (Amst.). 164:317-321.
22. Okada, A., S. Saez, Y. Misumi, and P. Basset. 1997. Rat stromelysin3: cDNA cloning from healing skin wound, activation by furin and expression in rat tissues. Gene (Amst.). 185:187-193.
23. Overall, C.M., and J. Sodek. 1990. Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. Induction and endogenous activation of collagenase, 72-kDa gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinases. J. Biol. Chem. 265:21141-21151.
24. Puente, X.S., A.M. Pendás, E. Llano, G. Velasco, and C. López-Otín. 1996. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res. 56:944-949.
25. Quinn, C.O., D.K. Scott, C.E. Brinckerhoff, L.M. Matrisian, J.J. Jeffrey, and N.C. Partridge. 1990. Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J. Biol. Chem. 265:22342-22347.
26. Rømer, J., T.H. Bugge, C. Pyke, L.R. Lund, M.J. Flick, J.L. Degen, and K. Danø. 1996. Impaired wound healing in mice with a disrupted plasminogen gene. Nature Med. 2:287-292.
27. Salo, T., M. Mäkelä, M. Kylmäniemi, H. Autio-Harmainen, and H. Larjava. 1994. Expression of matrix metalloproteinase-2 and -9 during early human wound healing. Lab. Invest. 70:176-182.
28. Santavicca, M., A. Noël, M.P. Chenard, Y. Lutz, I. Stoll, J.P. Segain, N. Rouyer, M.C. Rio, C. Wolf, J.P. Bellocq, and P. Basset. 1995. Characterization of monoclonal antibodies against stromelysin-3 and their use to evaluate stromelysin-3 levels in breast carcinoma by semi-quantitative immunohistochemistry. Int. J. Cancer. 64:336-341.
29. Santoro, M., C. Battaglia, L. Zhang, F. Carlomagno, M.L. Martelli, D. Salvatore, and A. Fusco. 1994. Cloning of the rat tissue inhibitor of metalloproteinases type 2 (TIMP-2) gene: analysis of its expression in normal and transformed thyroid cells. Exp. Cell Res. 213:398-403.
30. Sato, H., and M. Seiki. 1996. Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis. J. Biochem. 119:209-215.
31. Sato, H., T. Takino, Y. Okada, J. Cao, A. Shinagawa, E. Yamamoto, and M. Seiki. 1994. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (Lond.). 370:61-65.
32. Stetler-Stevenson, W.G., R. Hewitt, and M. Corcoran. 1996. Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic. Semin. Cancer Biol. 7:147-154.
33. Stricklin, G.P., L. Li, V. Jancic, B.A. Wenczak, and L.B. Nanney. 1993. Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds. Am. J. Pathol. 143:1657-1666.
34. Strongin, A.Y., I. Collier, G. Bannikov, B.L. Marmer, G.A. Grant, and G.I. Goldberg. 1995. Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J. Biol. Chem. 270:5331-5338.
35. Takino, T., H. Sato, A. Shinagawa, and M. Seiki. 1995. Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family. J. Biol. Chem. 270:23013-23020.
36. Tokuraku, M., H. Sato, S. Murakami, Y. Okada, Y. Watanabe, and M. Seiki. 1995. Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int. J. Cancer. 64:355-359.
37. Vassalli, J.D., and J.H. Saurat. 1996. Cuts and scrapes? Plasmin heals! Nature Med. 2:284-285.
38. Will, H., and B. Hinzmann. 1995. cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Eur. J. Biochem. 231:602-608.
39. Wu, I.M., and M.A. Moses. 1996. Cloning and expression of the cDNA encoding rat tissue inhibitor of metalloproteinase 3 (TIMP-3). Gene (Amst.). 168: 243-246.
40. Yamada, T., U. Yoshiyama, H. Sato, M. Seiki, A. Shinagawa, and M. Takahashi. 1995. White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues. Acta Neuropathol. 90:421-424.