Glycoprotein isolated from Solanum nigrum L. kills HT-29 cells through apoptosis

Journal of Medicinal Food

Volumn 8, Issue 2, 2005, Pages 215-226

  Lim, Kye Taek ^a  

^a Chonnam National University   (South Korea)

Author keywords

12 O tetradecanoylphorbol 13 acetate; Apoptosis; Glycoprotein of solanum nigrum L.; HT 29 cells; Nuclear factor B; Protein kinase C

Indexed keywords

ANTINEOPLASTIC AGENT; DNA FRAGMENT; GLYCOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE C ALPHA; PROTEIN KINASE C INHIBITOR; PYRROLIDINE DITHIOCARBAMATE; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL KILLING; CELL NUCLEUS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG ISOLATION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOLANUM NIGRUM; STAINING; TRADITIONAL MEDICINE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOPROTEINS; HT29 CELLS; HUMANS; NF-KAPPA B; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTO-ONCOGENE PROTEINS C-BCL-2; SOLANUM NIGRUM;

SOLANUM NIGRUM; SOLARIUM;

EID: 22444434850     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2005.8.215     Document Type: Article

References (56)

1. Sharma RA, Manson MM, Gescher A, Steward WP: Colorectal cancer chemoprevention: Biochemical targets and clinical development of promising agents. Eur J Cancer 2001;37:12-22.
2. Kerr JF, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
3. Green DR, Reed JC: Mitochondria and apoptosis. Science 1998;281:1309-1312.
4. Deigner HP, Kinscherf R: Modulating apoptosis: Current applications and prospects for future drug development. Curr Med Chem 1999;6:399-414.
5. Gross A, McDonnell JM, Korsmeyer SJ: BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999;13:1899-1911.
6. Evan G, Littlewood T: A matter of life and cell death. Science 1998;281:1317-1322.
7. Thornberry NA, Lazebnik Y: Caspases: Enemies within. Science 1998;281:1312-1316.
8. Gomez SL, Le GM, Clarke CA, Glaser SL, France AM, West DW: Cancer incidence patterns in Koreans in the US and in Kangwha, South Korea. Cancer Causes Control 2003;14:167-174.
9. Cummings JH, Bingham SA: Diet and the prevention of cancer. Br Med J 1998;317:1636-1640.
10. Lind DS, Hochwald SN, Malaty J, Rekkas S, Hebig P, Mishra G, Moldawer LL, Copeland EM 3rd, Mackay S: Nuclear factor-kappa B is upregulated in colorectal cancer. Surgery 2001;130: 363-369.
11. Lippman SM, Benner SE, Hong WK: Cancer chemoprevention. J Clin Oncol 1994;12:851-873.
12. Wattenberg LW: Chemoprevention of cancer. Cancer Res 1985; 45:1-8.
13. Fong LY, Feith DJ, Pegg AE: Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis. Cancer Res 2003;63:3945-3954.
14. Amin R, Kamitani H, Sultana H, Taniura S, Islam A, Sho A, Ishibashi M, Eling TE, Watanabe T: Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells. Neurol Res 2003;25:370-376.
15. Liu X, Pisha E, Tonetti DA, Yao D, Li Y, Yao J, Burdette JE, Bolton JL: Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites. Chem Res Toxicol 2003; 16:832-837.
16. Vecchia CL, Tavani A: Fruit and vegetables, and human cancer. Eur J Cancer Prev 1998;7:3-8.
17. Murakami A, Takahashi D, Kinoshita T, Koshimizu K, Kim HW, Yoshihiro A, Nakamura Y, Jiwajinda S, Terao J, Ohigashi H: Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: The alpha, beta-unsaturated carbonyl group is a prerequisite. Carcinogenesis 2002;23:795-802.
18. Rahmsdorf HJ, Herrlich P: Regulation of gene expression by tumor promoters. Pharmacol Ther 1990;48:157-188.
19. Davis PD, Hill CH, Keech E, Lawton G, Nixon JS, Sedgwick AD, Wadsworth J, Westmacott D, Wilkinson SE: Potent selective inhibitors of protein kinase C. FEBS Lett 1989;259:61-63.
20. Hass R, Pfannkuche HJ, Kharbanda S, Gunji H, Meyer G, Hartmann A, Hidaka H, Resch K, Kufe D, Goppelt-Strube M: Protein kinase C activation and protooncogene expression in differentiation/retrodifferentiation of human U-937 leukemia cells. Cell Growth Differ 1991;2:541-548.
21. Nishizuka Y: The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 1988:334: 661-665.
22. Craven PA, DeRubertis FR: Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation by unsaturated fatty acids. Gastroenterology 1988;95:676-685.
23. Jaken S, Leach K, Klauck T: Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts. J Cell Biol 1989;109:697-704.
24. Horwitz AR, Parsons JT: Cell migration-movin' on. Science 1999;286:1102-1103.
25. Pahl HL: Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999;18:6853-6866.
26. Dong Z, Ma W, Huang C, Yang CS: Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res 1997;57:4414-4419.
27. Barkett, M, Gilmore TD: Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 1999;18:6910-6924.
28. Sultana S, Perwaiz S, Iqbal M, Athar M: Crude extracts of hepatoprotective plants, Solanum nigrum and Cichorium intybus inhibit free radical-mediated DNA damage. J Ethnopharmacol 1995;45:189-192.
29. Ikeda T, Tsumagari H, Nohara T: Steroidal oligoglycosides from Solanum nigrum. Chem Pharin Bull (Tokyo) 2000;48:1062-1064.
30. Yen GC, Chen HY, Peng HH: Evaluation of the cytotoxicity, mutagenicity and antimutagenicity of emerging edible plants. Food Chem Toxicol 2001;39:1045-1053.
31. Prashanth Kumar V, Shashidhara S, Kumar MM, Sridhara BY: Cytoprotective role of Solanum nigrum against gentamicin-induced kidney cell (Vero cells) damage in vitro. Fitoterapia 2001;72:481-486.
32. Lee SJ, Lim KT: Antioxidative effects of glycoprotein isolated from Solanum nigrum Linne on oxygen radicals and its cytotoxic effects on the MCF-7 cell. J Food Sci 2003;68:466-470.
33. Lim KT, Heo KS, Son YO: Antioxidative and antimicrobial effects of glycoprotein isolated from Solanum nigrum Linne. Food Sci Biotechnol 2002;5:484-489.
34. Heo KS, Lim KT: Antioxidative effects of glycoprotein isolated from Solanum nigrum Linne. J Med Food 2004;7:349-357.
35. Wadsworth TL, Koop DR: Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages. Biochem Pharmacol 1999; 57:941-949.
36. Chun JS, Ha MJ, Jacobson BS: Differential translocation of protein kinase C ε during HeLa cell adhesion to a gelatin substratum. J Biol Chem 1996;27:13008-1312.
37. Dignam JD, Lebovitz RM, Roeder RG: Accurate transcription by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983;11:1475-1489.
38. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Polin phenol reagent. J Biol Chem 1951;193: 265-275.
39. Piao W, Yoo J, Lee DK, Hwang HJ, Kim JH: Induction of G2/M phase arrest and apoptosis by a new synthetic anticancer agent, DW2282, in promyelocytic leukemia (HL-60) cells. Biochem Pharmacol 2001;62:1439-1447.
40. Kitts DD, Lim KT: Antitumorigenic and cytotoxic properties of an ethanol extract derived from Rhus verniciflua Stokes (RVS). J Toxicol Environ Health A 2001;64:357-371.
41. Martinez-Cruz M, Zenteno E, Cordoba P: Purification and characterization of a galactose-specific lectin from corn (Zea mays) coleoptile. Biochim Biophys Acta 2001;1568:37-44.
42. Kimura Y, Miyagi C, Kimura M, Nitoda T, Kawai N, Sugimoto H: Structural features of N-glycans linked to royal jelly glycoproteins: Structures of high-mannose type, hybrid type, and biantennary type glycans. Biosci Biotechnol Biochem 2000;4: 2109-2120.
43. Karin M: How NF-kappa B is activated: The role of the Ikappa B kinase (IKK) complex. Oncogene 1999;18:6867-6874.
44. Yang L, Kim HT, Munoz-Medellin D, Reddy P, Brown PH: Induction of retinoid resistance in breast cancer cells by overexpression of cJun. Cancer Res 1997;57:4652-4661.
45. Fujihara SM, Nadler SG: Modulation of nuclear protein import: A novel means of regulating gene expression. Biochem Pharmacol 1998;56:157-161.
46. Bargou RC, Emmerich F, Krappmann D, Bommert K, Mapara My, Arnold W, Royer HD, Grinstein E, Greiner A, Scheidereit C, Dorken B: Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J Clin Invest 1997;100:2961-2969.
47. Wahl C, Liptay S, Adler G, Schmid RM: Sulfasalazine: A potent and specific inhibitor of nuclear factor kappa B. J Clin Invest 1998;101:1163-1174.
48. Scaife CL, Kuang J, Wills JC, Trowbridge DB, Gray P, Manning BM, Eichwald EJ, Daynes RA, Kuwada SK: Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: Implications for metastasis. Cancer Res 2002;62:6870-6878.
49. Barinaga M: Life-death balance within the cell. Science 1996;274: 724.
50. Giri DK, Aggarwal BB: Constitutive activation of NF-kappa B causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. J Biol Chem 1998;273:14008-14014.
51. Wei H, Wei L, Frenkel K, Bowen R, Barnes S: Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr Cancer 1993;20:1-12.
52. Murakami A, Ohura S, Nakamura Y, Koshimizu K, Ohigashi H: 1′-Acetoxychavicol acetate, a superoxide anion generation inhibitor, potently inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in ICR mouse skin. Oncology 1996;53: 386-391.
53. Cohen L, Henzel WJ, Baeuerle PA: IKAP is a scaffold protein of the IkappaB kinase complex. Nature 1998;395:292-296.
54. Okura T, Igase M, Kitami Y, Fukuoka T, Maguchi M, Kohara K, Hiwada K: Platelet-derived growth factor induces apoptosis in vascular smooth muscle cells. Biochim Biophys Acta 1998;1403: 245-253.
55. Kuo ML, Huang TS, Lin JK: Curcumin: An antioxidant and antitumor promoter, induces apoptosis in human leukemia cells. Biochim Biophys Acta 1996;1317:95-100.
56. Finucane DM, Ella BW, Waterhouse NJ, Cotter TG, Green DR: Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem 1999;274:2225-2233.