Induction of retinoid resistance in breast cancer cells by overexpression of cJun

Cancer Research

Volumn 57, Issue 20, 1997, Pages 4652-4661

  Yang, LiMin ^a   Kim, HeeTae ^a   Munoz Medellin, Deborah ^a   Reddy, Praveen ^a   Brown, Powel H ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOID;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INVASION; CELL PROLIFERATION; COMPLEX FORMATION; DNA BINDING; GENE EXPRESSION; GENE TARGETING; GENETIC RECOMBINATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TRANSACTIVATION;

BREAST NEOPLASMS; CELL DIVISION; DRUG RESISTANCE, NEOPLASM; FEMALE; GENES, JUN; GENES, REPORTER; HUMANS; KINETICS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-JUN; RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; RETINOID X RECEPTORS; RETINOIDS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0030856732     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Roberts, A. B., and Sporn, M. B. Cellular biology and biochemistry of the retinoids. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (ed.), The Retinoids, pp. 209-286, 443-520. Orlando, FL: Academic Press, 1984.
2. Lotan, R. Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. Biochim. Biophys. Acta, 605: 33-91, 1980.
3. Nakajima, M., Lotan, D., Baig, M. M., Carralero, R. M., Wood, W. R., Hendrix, M. J. C., and Lotan, R. Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells. Cancer Res., 49: 1698-1706, 1989.
4. Bollag, W., and Holdener, E. E. Retinoids in cancer prevention and therapy. Ann. Oncol., 3: 513-526, 1992.
5. Lacroix, A., and Lippman, M. E. Binding of retinoids to human breast cancer cell lines and their effects on cell growth. J. Clin. Invest., 65: 586-590, 1980.
6. Fontana, J. A., Hobbs, P. D., and Dawson, M. I. Inhibition of mammary carcinoma growth by retinoidal benzoic acid derivatives. Exp. Cell Biol., 56: 254-263, 1988.
7. Fanjul, A., Dawson, M. I., Hobbs, P. D., Jong, L., Cameron, J. F., Harlev, E., Graupner, G., Lu, X-P., and Pfahl, M. A new class of retinoids with selective inhibition of AP-1 inhibits proliferation. Nature (Lond.), 372: 107-111, 1994.
8. Seewaldt, V., Johnson, B. S., Parker, M. B., Collins, S. J., and Swisshelm, K. Expression of retinoic acid receptor β mediates retinoic acid-induced growth arrest and apoptosis in breast cancer cells. Cell Growth Differ., 7: 1077-1088, 1996.
9. Cobleigh, M. A., Dowlat, K., Minn, F., Benson, A. B., Rademaker, A. W., Ashenhurst, J. B., and Wade, J. L. Phase I trial of tamoxifen (TAM) with or without fenretinide (4HPR), an analogue of vitamin A, in patients with metastatic breast cancer. Breast Cancer Res. Treat., 190: 142, 1991.
10. Kelloff, G. J., and Boone, C. W. Cancer chemopreventive agents: drug development status and future prospects. J. Cell. Biochem., 10: 176-196, 1994.
11. Evans, R. M. The steroid and thyroid hormone receptor superfamily. Science (Washington DC), 240: 889-895, 1988.
12. Gudas, L. J. Retinoids, retinoid-response genes, cell differentiation and cancer. Cell Growth Differ., 3: 655-662, 1992.
13. Roman, S. D., Clarke, C. L., Hall, R. E., Alexander, I. E., and Sutherland, R. L. Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Res., 52: 2236-2242, 1992.
14. Swisshelm, K., Ryan, K., Lee, X., Tsou, H. C., Beacocke, M., and Sager, R. Down-regulation of retinoic acid receptor β in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells. Cell Growth Differ., 5: 133-141, 1994.
15. Zhao, Z., Zhang, Z-P., Soprano, D. R., and Soprano, K. J. Effect of 9-cis-retinoic acid on growth and RXR expression in human breast cancer cells. Exp. Cell Res., 219: 555-561, 1995.
16. Nagy, L., Thomazy, V. A., Shipley, G. L., Fesus, L., Lamph, W., Heyman, R. A., Chandraratna, R. A., and Davis, P. L. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol. Cell. Biol., 15: 3540-3551, 1995.
17. van der Burg, B., Slager-Davidov, R., van der Leede, B. M., de Laat, S. W., and van der Saag, P. T. Differential regulation of AP1 activity by retinoic acid in hormone-dependent and -independent breast cancer cells. Mol. Cell. Endocrinol., 112: 143-152, 1995.
18. Lee, H-Y., Dawson, M. I., Walsh, G. L., Nesbitt, J. C., Eckert, R. L., Fuchs, E., Hong, W. K., Lotan, R., and Kurie, J. M. Retinoic acid receptor-and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells. Cell Growth Differ., 7: 997-1004, 1996.
19. Angel, P., and Karin, M. The role of jun, fos and the AP-1 complex in cell-proliferation and transformation. Biochem. Biophys. Acta. 1072: 129-157, 1991.
20. Chen, T. K., Smith, L. M., Gebhardt, D. K., Birrer, M. J., and Brown, P. H. Activation and inhibition of the AP1 complex in human breast cancer cells. Mol. Carcinog., 15: 215-226, 1996.
21. Nicholson, R. C., Mader, S., Nagpal, S., Leid, M., Rochette-Egly, C., and Chambon, P. Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site. EMBO J., 9: 4443-4454, 1990.
22. Pfahl, M. Nuclear receptor/AP-1 interaction. Endocr. Rev., 14: 651-658, 1993.
23. Yang-Yen, H-F., Zhang, X-K., Graupner, G., Tzukerman, M., Sakamoto, B., Karin, M., and Pfahl, M. Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation. New Biol., 3: 1206-219, 1991.
24. Schule, R., Rangarajan, P., Yang, N., Kliewer, S., Ransone, L., Bolado, J., Verma, I. M., and Evans, R. M. Retinoic acid is a negative regulator of AP-1-responsive genes. Proc. Natl. Acad. Sci. USA, 88: 6092-6096, 1991.
25. Kamei, Y., Xu, L., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S-C., Heyman, R. A., Rose, D. W., Glass, C. K., and Rosenfeld, M. G. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell, 85: 403-414, 1996.
26. Chakaravarti, D., LaMorte, V. J., Nelson, M. C., Nakajima, T., Schulman, I. G., Juguilon, H., Montminy, M., and Evans, R. M. Role of CBP/P300 in nuclear receptor signalling. Nature (Lond.), 383: 99-103, 1996.
27. Schadlow, V. C., Barzilai, N., and Deutsch, P. J. Regulation of gene expression in PC12 cells via an activator of dual second messengers: pituitary adenylate cyclase activating polypeptide. Mol. Biol. Cell. 3: 941-951, 1992.
28. Yu, V. C., Delsert, C., Andersen, B., Holloway, J. M., Devary, O. V., Naar, A. M., Kim, S. Y., Boutin, J. M., Glass, C. K., and Rosenfeld, M. G. RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell, 67: 1251-1266, 1991.
29. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18: 5294-5299, 1979.
30. Szabo, E., Preis, L. H., Brown, P. H., and Birrer, M. J. The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation. Cell Growth Differ., 2: 475-482, 1991.
31. Feinberg, A. P., and Vogelstein, B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132: 6-13, 1983.
32. Yang, F., Fredrichs, W. E., Cupples, R. L., Bonifacio, M. L., Sanford, J. A., Horton, W. A., and Bowman, B. H. Human ceruloplasmin. Tissue-specific expression of transcripts produced by alternative splicing. J. Biol. Chem., 265: 10780-10785, 1990.
33. Liu, Y., Lee, M-O., Wang, H-G., Li, Y., Hashimoto, Y., Klaus, M., Reed, J. C., and Zhang, X-K. Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol. Cell. Biol., 16: 1138-1149, 1996.
34. van der Burg, B., van der Leede, B. M., Kwakkenbos-Isbrucker, L., Salverda, S., de Laat, S. W. and van der Saag, P. T. Retinoic acid resistance of estradiol-independent breast cancer cells coincides with diminished retinoic acid receptor function. Mol. Cell. Endocrinol., 91: 149-157, 1993.
35. Alani, R., Brown, P. H., Binetruy, B., Dosaka, H., Rosenberg, R. K., Angel, P., Karin, M., and Birrer, M. J. The transactivating function of the cJun proto-oncoprotein is required for cotransformation of rat embryo cells. Mol. Cell. Biol., 11: 6286-6295, 1991.
36. Brown, P. H., Alani, R., Preis, L. H., Szabo, E., and Birrer, M. J. Suppression of oncogene-induced transformation by a deletion mutant of c-jun. Oncogene, 8. 877-886, 1993.
37. Brown, P. H., Chen, T., Szabo, E., and Birrer, M. J. Mechanism of action of a dominant-negative mutant of c-jun. Oncogene, 9: 791-800 1994.
38. Kastner, P., Mark, M., and Chambon, P. Nonsteroid nudear receptors. What are genetic studies telling us about their role in real life? Cell, 83: 859-869, 1995.
39. Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., LeMeur, M., Decimo, D., Vonesch, J. L., Dolle, P., and Chambon, P. Genetic analysts of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell, 78: 987-1003, 1994.
40. Ahn, M. J., Langenfeld, J., Moasser, M. M., Rusch, V., and Dmitrovsky, E. Growth suppression of transformed human bronchial epithelial cells by all-trans-retinoic acid occurs through specific retinoid receptors. Oncogene, 11: 2357-2364, 1995.
41. Moasser, M. M., Reuter, V. E., and Dmitrovsky, E. Overexpression of the retinoic acid receptor gamma directly induces terminal differentiation of human embryonal carcinoma cells. Oncogene, 10: 1537-1543, 1995.
42. Sheikh, M. S., Shao, Z-M., Li, X-S., Dawson, M., Jetten, A. M., Wu, S., Conley, B. A., Garcia, M., Rochefort, H., and Fontana, J. A. Retinoid-resistan, estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoids. J. Biol. Chem., 269: 21440-21447, 1994.
43. Dawson, M. I., Chao, W., Pine, P., Jong, L., Hobbs, P. D., Rudd, C. K., QuicK, T. C., Niles, R. M., Zhang, X-K., Lombardo, A., Ely, K. R., Shroot, B., and Fontana, J. A. Correlation of retinoid binding affinity to retinoic acid receptor α with retinoid inhibition of growth of estrogen receptor-positive MCF-7 mammary carcinoma cells. Cancer Res., 55: 4446-4451, 1995.