Possible pathway(s) of testosterone egress from the active site of cytochrome P450 2B1: A steered molecular dynamics simulation

Drug Metabolism and Disposition

Volumn 33, Issue 7, 2005, Pages 910-919

  Li, Weihua ^a   Liu, Hong ^a   Scott, Emily E ^c   Gräter, Frauke ^a   Halpert, James R ^b   Luo, Xiaoming ^a   Shen, Jianhua ^a   Jiang, Hualiang ^a,d  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2B1; PHENYLALANINE DERIVATIVE; TESTOSTERONE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHANNEL GATING; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; TESTOSTERONE;

PYRONIA TITHONUS;

EID: 22344439844     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.105.004200     Document Type: Article

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