How do substrates enter and products exit the buried active site of cytochrome P450cam? 2. Steered molecular dynamics and adiabatic mapping of substrate pathways

Journal of Molecular Biology

Volumn 303, Issue 5, 2000, Pages 813-830

  Lüdemann, Susanna K ^a   Lounnas, Valère ^a   Wade, Rebecca C ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Buried active site; Cytochrome P450; Enzyme substrate binding; Molecular dynamics simulation; Protein dynamics

Indexed keywords

CAMPHOR 5 MONOOXYGENASE;

ARTICLE; ENERGY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SIMULATION; TIME;

DRYOBALANOPS;

EID: 0034634391     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4155     Document Type: Article

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