Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats

Physiological Research

Volumn 54, Issue 6, 2005, Pages 631-637

  Ozdemir, D ^a   Uysal, N ^a   Gonenc, S ^a   Acikgoz, O ^a   Sonmez, A ^a   Topcu, A ^a   Ozdemir, N ^b   Duman, M ^a   Semin, I ^a   Ozkan, H ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

^b ATATURK TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Glutathione peroxidase (GPx); Immature rat; Lipid peroxidation; Melatonin; Superoxide dismutase (SOD); Traumatic brain injury (TBI)

Indexed keywords

ANTIOXIDANT; GLUTATHIONE PEROXIDASE; MELATONIN; SCAVENGER; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN CONTUSION; BRAIN OXYGEN CONSUMPTION; BRAIN REGION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME BLOOD LEVEL; FEMALE; HEMISPHERE; IMMATURITY; LIPID PEROXIDATION; NONHUMAN; OXIDATION; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; GLUTATHIONE PEROXIDASE; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; MELATONIN; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 22144489589     PISSN: 08628408     EISSN: 08628408     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. ADELSON PD, KOCHANEK PM: Head injury in children. J Child Neurol 13: 2-15, 1998.
2. BAYIR H, KOCHANEK PM, CLARK RS: Traumatic brain injury in infants and children: mechanisms of secondary damage and treatment in the intensive care unit. Crit Care Clin 19: 529-549, 2003.
3. BITTIGAU P, SIFRINGER M, POHL D, STADTHAUS D, ISHIMARU M, SHIMIZU H, IKEDA M, LANG D, SPEER A, OLNEY JW, IKONOMIDOU C: Apoptotic neurodegeneration following trauma is markedly enhanced in the immature brain. Ann Neurol 45: 724-735, 1999.
4. BUONOCORE G, PERRONE S, BRACCI R: Free radicals and brain damage in the newborn. Biol Neonate 79: 180-186, 2001.
5. BUONOCORE G, PERRONE S, LONGINI M, VEZZOSI P, MARZOCCHI B, PAFFETTI P, BRACCI R: Oxidative stress in preterm neonates at birth and on the seventh day of life. Pediatr Res 52: 46-49, 2002.
6. CARRILLO MC, KANAI S, NOKUBO M, KITANI K: (-) Deprenyl induces activities of both superoxide dismutase and catalase but not of glutathione peroxidase in the striatum of young male rats. Life Sci 48: 517-521, 1991.
7. CIRAK B, ROUSAN N, KOCAK A, PALAOGLU O, PALAOGLU S, KILIC K: Melatonin as a free radical scavenger in experimental head trauma. Pediatr Neurosurg 31: 298-301, 1999.
8. COLICOS MA, DIXON CE, DASH PK: Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory deficits. Brain Res 739: 111-119, 1996.
9. CUZZOCREA S, REITER RJ: Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. Eur J Pharmacol 426: 1-10, 2001.
10. DELMAS-BEAUVIEUX MC, PEUCHANT E, DUMON MF, RECEVEUR MC, LE BRAS M, CLERC M: Relationship between red blood cell antioxidant enzymatic system status and lipoperoxidation during the acute phase of malaria. Clin Biochem 28: 163-169, 1995.
11. EVANS PH: Free radicals in brain metabolism and pathology. Br Med Bull 49: 577-587, 1993.
12. FAN P, YAMAUCHI T, NOBLE LJ, FERRIERO DM: Age-dependent differences in glutathione peroxidase activity after traumatic brain injury. J Neurotrauma 20: 437-445, 2003.
13. FEUERSTEIN GZ, WANG X, BARONE FC: Inflammatory gene expression in cerebral ischemia and trauma. Potential new therapeutic targets. Ann N Y Acad Sci 825: 179-193, 1997.
14. GARCIA JJ, REITER RJ, GUERRERO JM, ESCAMES G, YU BP, OH CS, MUNOZ-HOYOS A: Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation. FEBS Lett 408: 297-300, 1997.
15. GILAD E, CUZZOCREA S, ZINGARELLI B, SALZMAN AL, SZABO C: Melatonin is a scavenger of peroxynitrite. Life Sci 60: PL169-PL174, 1997.
16. HAGEMAN JJ, BAST A, VERMEULEN NP: Monitoring of oxidative free radical damage in vivo: analytical aspects. Chem Biol Interact 82: 243-93, 1992.
17. KABUTO H, YOKOI I, OGAWA N. Melatonin inhibits iron-induced epileptic discharges in rats by suppressing peroxidation. Epilepsia 39: 237-243, 1998.
18. KASPRZAK HA, WOZNIAK A, DREWA G, WOZNIAK B: Enhanced lipid peroxidation processes in patients after brain contusion. J Neurotrauma 18: 793-797, 2001.
19. KOSKINIEMI M, KYYKKA T, NYBO T, JARHO L: Long-term outcome after severe brain injury in preschoolers is worse than expected. Arch Pediatr Adolesc Med 149: 249-254, 1995.
20. MELCHIORRI D, REITER RJ, SEWERYNEK E, CHEN LD, NISTICO G: Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions. FASEB J 9: 1205-1210, 1995.
21. OKATANI Y, WAKATSUKI A, KANEDA C: Melatonin increases activities of glutathione peroxidase and superoxide dismutase in fetal rat brain. J Pineal Res 28: 89-96, 2000.
22. PAGLIA DE, VALENTINE WN: Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70: 158-169, 1967.
23. PEKÁRKOVÁ I, PARARA S, HOLEEK V, STOPKA P, TREFIL L, RACEK J, ROKYTA R: Does exogenous melatonin influence the free radicals metabolism and pain sensation in rat? Physiol Res 50: 595-602, 2001.
24. 2+ and ascorbic acid-stimulated lipid peroxidation in vitro. J Neurochem 34: 1630-1638, 1980.
25. REITER RJ: Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 56: 359-384, 1998.
26. REITER RJ, TAN DX, OSUNA C, GITTO E: Actions of melatonin in the reduction of oxidative stress. A review. J Biomed Sci 7: 444-458, 2000a.
27. REITER RJ, TAN DX, QI W, MANCHESTER LC, KARBOWNIK M, CALVO JR: Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo. Biol Signals Recept 9: 160-167, 2000b.
28. RODRIGUEZ C, MAYO JC, SAINZ RM, ANTOLIN I, HERRERA F, MARTIN V, REITER RJ: Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 36: 1-9, 2004.
29. ROGERIO F, DE SOUZA QUEIROZ L, TEIXEIRA SA, OLIVEIRA AL, DE NUCCI G, LANGONE F: Neuroprotective action of melatonin on neonatal rat motoneurons after sciatic nerve transection. Brain Res 926: 33-34, 2002.
30. SEWERYNEK E, MELCHIORRI D, CHEN L, REITER RJ: Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro. Free Radic Biol Med 19: 903-909, 1995.
31. SHOHAMI E, BEIT-YANNAI E, HOROWITZ M, KOHEN R: Oxidative stress in closed-head injury: brain antioxidant capacity as an indicator of functional outcome. J Cereb Blood Flow Metab 17: 1007-1019, 1997.
32. SOLAR P: Melatonin and its wide-spectrum effects: use of melatonin in the treatment of tumors. Cesk Fysiol 48: 27-40, 1999.
33. STEIN SC, SPETTELL CM: Delayed and progressive brain injury in children and adolescents with head trauma. Pediatr Neurosurg 23: 299-304, 1995.
34. TAN DX, MANCHESTER LC, REITER RJ, PLUMMER BF, LIMSON J, WEINTRAUB ST, QI W: Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. Free Radic Biol Med 29: 1177-1185, 2000.
35. TYURIN VA, TYURINA YY, BORISENKO GG, SOKOLOVA TV, RITOV VB, QUINN PJ, ROSE M, KOCHANEK P, GRAHAM SH, KAGAN VE: Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates. J Neurochem 75: 2178-2189, 2000.
36. UNDEGER U, GIRAY B, ZORLU AF, OGE K, BACARAN N: Protective effects of melatonin on the ionizing radiation induced DNA damage in the rat brain. Exp Toxicol Pathol 55: 379-384, 2004.
37. USTUN ME, DUMAN A, OGUN CO, SUMER F, GURBILEK M: Effects of deferoxamine on tissue superoxide dismutase and glutathione peroxidase levels in experimental head trauma. J Trauma 51: 22-25, 2001a.
38. USTUN ME, DUMAN A, OGUN CO, VATANSEV H, AK A: Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. J Neurosurg Anesthesiol 13: 227-232, 2001b.
39. WAKATSUKI A, OKATANI Y, IZUMIYA C, IKENOUE N: Melatonin protects against ischemia and reperfusioninduced oxidative lipid and DNA damage in fetal rat brain. J Pineal Res 26: 147-152, 1999.
40. WAKATSUKI A, OKATANI Y, SHINOHARA K, IKENOUE N, KANEDA C, FUKAYA T: Melatonin protects fetal rat brain against oxidative mitochondrial damage. J Pineal Res 30: 22-28, 2001a.
41. WAKATSUKI A, OKATANI Y, SHINOHARA K, IKENOUE N, FUKAYA T: Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain. J Pineal Res 31: 167-172, 2001b.
42. WATANABE N, KAMEI S, OHKUBO A, YAMANAKA M, OHSAWA S, MAKINO K, TOKUDA K: Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer. Clin Chem 32: 1551-1554, 1986.
43. YAMAMOTO HA, MOHANAN PV: Melatonin attenuates brain mitochondria DNA damage induced by potassium cyanide in vivo and in vitro. Toxicology 179: 29-36, 2002.
44. YAMAMOTO H, TANG H: Melatonin attenuates L-cysteine-induced seizures and lipid peroxidation in the brain of mice. J Pineal Res 21: 108-113, 1996.