C-fos protein expression in the nucleus of the solitary tract correlates with cholecystokinin dose injected and food intake in rats

Brain Research

Volumn 846, Issue 1, 1999, Pages 1-11

  Zittel, Tilman T ^a   Glatzle, Jörg ^a   Kreis, Martin E ^a   Starlinger, M ^a   Eichner, M ^a   Raybould, Helen E ^b   Becker, Horst D ^a   Jehle, Ekkehard C ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain gut axis; C fos protein; Cholecystokinin; Regulation of food intake; Satiety

Indexed keywords

CHOLECYSTOKININ; PROTEIN C FOS;

ANIMAL EXPERIMENT; AREA POSTREMA; ARTICLE; BRAIN STEM; CONTROLLED STUDY; FOOD INTAKE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGRESSION ANALYSIS; REGULATORY MECHANISM; SATIETY; SENSORY NERVE; SHAM FEEDING; VAGUS NERVE;

ANIMALS; CHOLECYSTOKININ; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; INTESTINES; LOGISTIC MODELS; MALE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHOLECYSTOKININ; SATIATION; SOLITARY NUCLEUS; VAGUS NERVE;

EID: 0032861493     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01842-9     Document Type: Article

References (56)

1. S. M. Altschuler, L. Rinaman, R.R. Miselis, Viscerotopic representation of the alimentary tract in the dorsal and ventral vagal complexes in the rat, in: S. Ritter, R.C. Ritter, C.D. Barnes (Eds.), Neuroanatomy and Physiology of Abdominal Vagal Afferents, CRC Press, Boca Raton, 1992, pp. 21-53.
2. Banks W.A., Kastin A.J. Permeability of the blood-brain barrier to neuropeptides: a case for penetration. Psychoneuroendocrinology. 10:1985;385-399.
3. Canova A., Geary H. Intraperitoneal injections of nanogram CCK-8 doses inhibit feeding in rats. Appetite. 17:1991;221-227.
4. Chen D.-Y., Deutsch J.A., Gonzalez M.F., Gu Y. The induction and suppression of c-fos expression in the rat brain by cholecystokinin and ist antagonist L364,718. Neurosci. Lett. 149:1993;91-94.
5. Crawley J.N., Rojas-Ramirez J.A., Mendelson W.B. The role of central and peripheral cholecystokinin in mediating appetitive behaviors. Peptides. 3:1982;535-538.
6. Crawley J.N., Schwaber J.S. Abolition of the behavioral effects of cholecystokinin following bilateral radiofrequency lesions of the parvocellular subdivions of the nucleus of the solitary tract. Brain Res. 295:1984;289-299.
7. Curry S.H., McCarthy D., Morris C.F., Simpson-Heren L. Whole body autoradiography of CCK-8 in rats. Regul. Pept. 55:1995;179-188.
8. A receptor mechanism. Neuropharmacology. 33:1994;719-727.
9. Dourish C.T., Rycroft W., Iversen S.D. Postponement of satiety by blockade of brain cholecystokinin (CCK-B) receptors. Science. 245:1989;1509-1511.
10. Dragunow M., Faull R. The use of c-fos as a metabolic marker in neuronal pathway tracing. J. Neurosci. Methods. 29:1989;261-265.
11. Edwards G.L., Ladenheim E.E., Ritter R.C. Dorsomedial hindbrain participation in cholecystokinin-induced satiety. Am. J. Physiol. 251:1986;R971-R977.
12. Ferguson A.V., Donevan S.D., Papas S., Smith S.M. Circumventricular structures: CNS sensors of circulating peptides and autonomic control centers. Endocrinol. Exp. 24:1990;19-27.
13. Fraser K.A., Davison J.S. Cholecystokinin-induced c-fos expression in the rat brain stem is influenced by vagal nerve integrity. Exp. Physiol. 77:1992;225-228.
14. Fraser K.A., Davison J.S. Meal-induced c-fos expression in brain stem is not dependent on cholecystokinin release. Am. J. Physiol. 265:1993;R235-R239.
15. Fraser K.A., Raizada E., Davison J.S. Oral-pharyngeal-esophageal and gastric cues contribute to meal-induced c-fos expression. Am. J. Physiol. 268:1995;R223-R230.
16. Garlicki J., Konturek P.K., Majka J., Kwiecien N., Konturek S.J. Cholecystokinin receptors and vagal nerves in control of food intake in rats. Am. J. Physiol. 258:1990;E40-E45.
17. Gibbs J., Young R.C., Smith G.P. Cholecystokinin decreases food intake in rats. J. Comp. Physiol. Psychol. 84:1973;488-495.
18. Grill H.J., Smith G.P. Cholecystokinin decreases sucrose intake in chronic decerebrate rats. Am. J. Physiol. 254:1988;R853-R856.
19. H.J. Grill, J.M. Kaplan, Caudal brainstem participates in the distributed neural control of feeding, in: E.M. Stricker (Ed.), Handbook of Behavioral Neurobiology, Plenum, New York, 1990, pp. 125.
20. Hill D.R., Woodruff G.N. Differentiation of central cholecystokinin receptor binding sites using the non-peptide antagonist MK-329 and L-365,269. Brain Res. 526:1990;276-283.
21. Joyner K., Smith G.P., Gibbs J. Abdominal vagotomy decreases the satiating potency of CCK-8 in sham and real feeding. Am. J. Physiol. 264:1993;R912-R916.
22. Kissileff H.R., Pi-Sunyer X., Thornton J., Smith G.P. C-terminal octapeptide of cholecystokinin decreases food intake in man. Am. J. Clin. Nutr. 34:1981;154-160.
23. Kreis M.E., Zittel T.T., Raybould H.E., Reeve J.R., Grundy D. Prolonged intestinal afferent nerve discharge in response to cholecystokinin 58 compared to cholecystokinin 8. Neurosci. Lett. 230:1997;89-92.
24. Le Sauter J., Geary N N. Redundant vagal mediation of the synergistic satiety effect of pancreatic glucagon and cholecystokinin in sham feeding rats. J. Auton. Nerv. Syst. 30:1990;13-22.
25. Linden A., Uvnäs-Moberg K., Forsberg G., Bednar I., Södersten P. Plasma concentrations of cholecystokinin octapeptide and food intake in male rats treated with cholecystokinin octapeptide. J. Endocrinol. 121:1989;59-65.
26. Linden A., Södersten P. Relationship between the concentration of cholecystokinin- like immunoreactivity in plasma and food intake in male rats. Physiol. Behav. 48:1990;859-863.
27. Luckman S.M. Fos-like immunoreactivity in the brain stem of the rat following peripheral administration of cholecystokinin. J. Neuroendocrinol. 4:1992;149-152.
28. Miller A.D., Leslie R.A. The area postrema and vomiting. Front. Neuroendocrinol. 15:1994;301-320.
29. Mönnikes H., Lauer G., Tebbe J., Zittel T.T., Arnold R. Pathways of Fos expression in locus coeruleus, dorsal vagal complex and paraventricular nucleus in response to intestinal lipid. Am. J. Physiol. 273:1997;R2059-R2071.
30. T.H. Moran, P.R. McHugh, Anatomical and pharmacological differentiation of pyloric, vagal and brain stem cholecystokinin receptors, in: R.Y. Wang, R. Schoenfeld (Eds.), Cholecystokinin Antagonists, Alan R. Liss, New York, 1988, p. 117.
31. T.H. Moran, Receptor subtype and affinity state underlying the satiety actions of cholecystokinin, in: S.J. Cooper, P.G. Clifton (Eds.), Drug Receptor Subtypes and Ingestive Behaviour, Academic Press, London, 1996, p. 1.
32. Morgan J.I., Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Ann. Rev. Neurosci. 14:1991;421-451.
33. Morley J.E., Levine A.S., Bartness T.J., Nizielski S.E., Shaw M.J., Hughes J.J. Species differences in the response to cholecystokinin. Ann. N.Y. Acad. Sci. 488:1985;413-416.
34. Morley J.E. Neuropeptide regulation of appetite and weight. Endocrine Rev. 8:1987;256-287.
35. Olson B.R., Freilino M., Hoffman G.E., Stricker E.M., Sved A.F., Verbalis J.G. c-fos expression in rat brain and brainstem nuclei in response to treatments that alter food intake and gastric motility. Mol. Cell. Neurosci. 4:1993;93-106.
36. Phifer C.B., Berthoud H.-R. Duodenal nutrient infusions differentially affect sham feeding and fos expression in the rat brain stem. Am. J. Physiol. 274:1998;R1725-R1733.
37. Passaro E., Debas H., Oldendorf W., Yamada T. Rapid appearance of intraventricularly administered neuropeptides in the peripheral circulation. Brain Res. 214:1982;338-340.
38. G. Paxinos, C. Watson, (Eds.), The Rat Brain in Stereotaxic Coordinates, 4th edn., Academic Press, San Diego, 1998.
39. Raybould H.E., Gayton R.J., Dockray G.J. Mechanisms of action of peripherally administered cholecystokinin octapeptide on brain stem neurons in the rat. J. Neurosci. 8:1988;3018-3024.
40. Reidelberger R.D. Abdominal vagotomy mediation of the satiety effects of exogenous and endogenous cholecystokinin in rats. Am. J. Physiol. 263:1992;R1354-R1358.
41. Ricardo J.A., Koh E.T. Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Res. 153:1978;1-26.
42. Rinaman L., Card J.P., Schwaber J.S., Miselis R.R. Ultrastructural demonstration of a gastric monosynaptic vagal circuit in the nucleus of the solitary tract in rat. J. Neurosci. 9:1989;1985-1996.
43. R.C. Ritter, S. Ritter, C.D. Barnes (Eds.), Feeding behavior. Neural and humoral controls, Academic Press, Orlando, 1986.
44. Rutherfurd S.D., Widdop R.E., Sannajust F., Louis W.J., Gundlach A.L. Expression of c-fos and NGFI-A messenger RNA in the medulla oblongata of the anaesthetized rat following stimulation of vagal and cardiovascular afferents. Mol. Brain Res. 13:1992;301-312.
45. Sagar S.M.F., Sharp F.R., Curran T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science. 240:1988;1328-1331.
46. R. Samanin, G. Grignaschi, Role of 5-hydroxytryptamine receptor subtypes in satiety and animal models of eating disorders, in: S.J. Cooper, P.G. Clifton, (Eds.), Drug Receptor Subtypes And Ingestive Behaviour, Academic Press, London, 1996, p. 39.
47. K.J. Simansky. 5-HT receptor subtypes influencing feeding and drinking: focus on the periphery, in: S.J. Cooper, P.G. Clifton, (Eds.), Drug Receptor Subtypes and Ingestive Behaviour, Academic Press, London, 1996, p. 59.
48. Smith G.P., Jerome C., Norgren R. Afferent axons in abdominal vagus mediate satiety effect of cholecystokinin in rats. Am. J. Physiol. 249:1985;R638-R641.
49. Somerville E, P.G. Clifton, Neurochemical interactions in the control of ingestive behaviour, in: S.J. Cooper, P.G. Clifton, (Eds.), Drug Receptor Subtypes and Ingestive Behaviour, Academic Press, London, 1996, p. 369.
50. L.W. Swanson, (Ed.), Brain Maps: Structure of the Rat Brain, Elsevier, Amsterdam, 1992.
51. Verbalis J.G., Stricker E.M., Robinson A.G., Hoffman G.E. Cholecystokinin activates c-fos expression in hypothalamic oxytocin and corticotropin-releasing hormone neurons. J. Neuroendocrinol. 3:1991;205-213.
52. Willing A.E., Berthoud H.-R. Gastric distension-induced c-fos expression in catecholaminergic neurons of rat dorsal vagal complex. Am. J. Physiol. 272:1997;R59-R67.
53. Zarbin M.A., Wamsley J.K., Innis R.B., Kuhar M.J. Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve. Life Sci. 29:1981;697-705.
54. Zittel T.T., De Giorgio R., Brecha N.C., Sternini C., Raybould H.E. Abdominal surgery induces c-fos expression in the nucleus of the solitary tract in the rat. Neurosci. Lett. 159:1993;79-82.
55. Zittel T.T., De Giorgio R., Sternini C., Raybould H.E. Fos protein expression in the nucleus of the solitary tract in response to intestinal nutrients in awake rats. Brain Res. 663:1994;266-270.
56. Zittel T.T., Glatzle J., Behler A., Starlinger M.J., Becker H.D. C-fos protein expression in the nucleus of the solitary tract correlates with food intake and cholecystokinin dose injected in rats. Gastroenterology. 112:1997;A1204.