Overexpression of cholecystokinin-B/gastrin receptor gene in the stomach of naturally occurring cholecystokinin-A receptor gene knockout rats

Digestion

Volumn 59, Issue 1, 1998, Pages 26-32

  Miyasaka, Kyoko ^a   Kanai, Setsuko ^a   Ohta, Minoru ^a   Jimi, Atsuo ^b   Kono, Akira ^c   Funakoshi, Akihiro ^c  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

Cholecystokinin A receptor; Cholecystokinin B gastrin receptor; Gastric acid secretion; Gene expression; H+ K+ ATPase; Parietal cell; Somatostatin

Indexed keywords

CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; GASTRIN; GASTRIN RECEPTOR; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MESSENGER RNA; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GASTRIN BLOOD LEVEL; GENE OVEREXPRESSION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR GENE; STOMACH; STOMACH ACID SECRETION; STOMACH MUCOSA; STOMACH PARIETAL CELL;

ANIMALS; BLOTTING, NORTHERN; GASTRIC ACID; GASTRINS; MALE; PARIETAL CELLS, GASTRIC; RATS; RECEPTORS, CHOLECYSTOKININ; RNA, MESSENGER; SOMATOSTATIN; UP-REGULATION;

EID: 0031983010     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000007463     Document Type: Article

References (34)

1. Funakoshi A, Miyasaka K, Jimi A, Kawanami T, Takata Y, Kono A: Little or no expression of the cholecystokinin-A receptor gene in the pancreas of diabetic rats (Otsuka Long-Evans Tokushima Fatty = OTLEF rats). Biochem Biophys Res Commun 1994;199:482-488.
2. Funakoshi A, Miyasaka K, Shinozaki H, Masuda M, Kawanami T, Takata Y, Kono A: An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor. Biochem Biophys Res Commun 1995;210: 787-796.
3. Takata Y, Takiguchi S, Funakoshi A, Kono A: Gene structure of rat cholecystokinin type-A receptor. Biochem Biophys Res Commun 1995;213:958-966.
4. Funakoshi A, Kono A, Miyasaka K: Lack of appropriate citation (letter to the editor). Am J Physiol 1996;33:E373.
5. Chang RS, Lotti VJ: Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist. Proc Natl Acad Sci USA 1986;83: 4923-4926.
6. Jensen RT, Murphy BR, Trampota M, Schneider LH, Jones SW, Howard JM, Gardner JD: Proglumide analogue: Potent cholecystokinin receptor antagonists. Am J Physiol 1985;249:G214-G220.
7. Lotti VJ, Chang RS: A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260. Eur J Pharmacol 1989;162:273-280.
8. Kopin AS, Lee YM, McBride EW, Miller LJ, Lu M, Lin HY, Kolakowski LF Jr, Beinborn M: Expression, cloning and characterization of the canine parietal cell gastrin receptor. Proc Natl Acad Sci USA 1992;89:3605-3609.
9. Wank SA, Harkins R, Jensen RT, Shapira H, De Weerth A, Slattery T: Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. Proc Natl Acad Sci USA 1992;89:3125-3129.
10. Wank SA, Pisegna JR, De Weerth A: Brain and gastrointestinal cholecystokinin receptor family: Structure and functional expression. Proc Natl Acad Sci USA 1992;89:8691-8695.
11. Hill DR, Campell NJ, Shaw TM, Woodruff GN: Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists. J Neurosci 1987;7:2967-2976.
12. 3H-MK 329. J Neurosci 1990;10:1070-1081.
13. Miyasaka K, Kanai S, Ohta M, Kawanami T, Kono A, Funakoshi A: Lack of satiety effect of cholecystokinin (CCK) in a new rat model not expressing the CCK-A receptor gene. Neurosci Lett 1994;180:143-146.
14. +)-ATPase. J Biol Chem 1986;261:16788-16791.
15. +-ATPase mRNA induced by intravenous infusion of gastrin 17 and histamine. Dig Dis Sci 1995;40:2064-2069.
16. Lloyd KC, Raybould HE, Walsh JH: Cholecystokinin inhibits gastric acid secretion through type 'A' cholecystokinin receptors and somatostatin in rats. Am J Physiol 1992;263: G287-G292.
17. Funakoshi A, Miyasaka K, Kitani K, Nakamura J, Funakoshi S, Fukuda H, Fujii N: Stimulatory effect of islet amyloid polypeptide (amylin) on exocrine pancreas and gastrin release in conscious rats. Regul Pept 1992;38:135-143.
18. Kobayashi S, Ohta M, Miyasaka K, Funakoshi A: Decrease in exploratory behavior in naturally occurring cholecystokinin (CCK)-A receptor gene knockout rats. Neurosci Lett 1996;214: 61-64.
19. Miyasaka K, Masuda M, Kawanami T, Funakoshi A: Neurohormonal regulation of pancreatic exocrine function in rats without gene expression of cholecystokinin-A receptor. Pancreas 1996;12:272-279.
20. Miyasaka K, Ohta M, Kanai S, Sato Y, Masuda M, Funakoshi A: Role of cholecystokinin (CCK) A receptor for pancreatic growth after weaning: A study in a new rat model without gene expression of CCK A receptor. Pancreas 1996;12:351-356.
21. Miyasaka K, Ohta M, Masuda M, Funakoshi A: Retardation of pancreatic regeneration after partial pancreatectomy in a strain of rats without CCK-A receptor gene expression. Pancreas 1997;14:391-399.
22. Funakoshi A, Miyasaka K, Kanai S, Masuda M, Yasunami Y, Nagai T, Ikeda S, Jimi A, Kawanami T, Kono A: Pancreatic endocrine dysfunction in rats not expressing the cholecystokinin-A receptor. Pancreas 1996;12:230-236.
23. Ohta M, Masuda M, Miyasaka K, Funakoshi A: Changes in intestinal enzyme activities in rats without gene expression of CCK-A receptor (in Japanese). Dig Absorpt 1995;18:103-107.
24. Gantz I, Munzert G, Tashiro T, Schaffer M, Wang L, DelValle J, Yamada T: Molecular cloning of the human histamine H2 receptor. Biochem Biophys Res Commun 1991;178: 1386-1392.
25. Kajimura M, Reuben MA, Sachs G: The muscarinic receptor gene expressed in rabbit parietal cells is the m3 subtype. Gastroenterology 1992;103:870-875.
26. Welsh NJ, Shankley NP, Black JW: Application of a model to explore interspecies differences in acetylcholine M-receptor-stimulated gastric acid secretion. Br J Pharmacol 1995; 115:961-968.
27. Nagata A, Ito M, Iwata N, Kuno J, Takano H, Minowa O, Chihara K, Matsui T, Noda T: G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vitro. Proc Natl Acad Sci 1996;93:11825-11830.
28. Langhans N, Rindi G, Chiu M, Rehfeld JF, Ardman B, Beinborn M, Kopin AS: Abnormal gastric histology and decreased acid production in cholecystokinin-B/gastrin receptor-deficient mice. Gastroenterology 1997;112:280-286.
29. Walsh JH, Richardson CT, Fordtran JS: pH dependence of acid secretion and gastrin release in normal and ulcer subjects. J Clin Invest 1975;55:462-468.
30. Buchan AM, Meloche RM, Kwok YN, Kofod H: Effect of cholecystokinin and secretin on somatostatin release from cultured antral cells. Gastroenterology 1993;104:1414-1419.
31. Moran TH, McHugh PR: Cholecystokinin suppresses food intake by inhibiting gastric emptying. Am J Physiol 1982;242:R491-R497.
32. Pradhan TK, Qian JM, Sutliff VE, Mantey SA, Jensen RT: Identification of CCK-A receptors on chief cells with use of a novel, highly selective ligand. Am J Physiol 1995;268:G605-G612.
33. Tachibana I, Akiyama T, Kanagawa K, Shirohara H, Fukumi K, Watanabe N, Otsuki M: Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats. Am J Physiol 1996;270:G730-G737.
34. Song I, Brown DR, Wiltshire RN, Gantz I, Trent JM, Yamada T: The human gastrin/cholecystokinin type B receptor gene: Alternative splice donor site in exon 4 generates two variant mRNA. Proc Natl Acad Sci USA 1993;90: 9085-9089.