Response of the gastric vagal afferent activity to cholecystokinin in rats lacking type A cholecystokinin receptors

Journal of the Autonomic Nervous System

Volumn 75, Issue 1, 1999, Pages 51-59

  Kurosawa, Mieko ^a   Bucinskaite, Violeta ^b   Taniguchi, Takamichi ^a   Miyasaka, Kyoko ^c   Funakoshi, Akihiro ^d   Lundeberg, Thomas ^b  

^a INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^b KAROLINSKA INSTITUTE   (Sweden)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^d NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

Cholecystokinin; Gastric vagal afferent; Long Evans Tokushima Otsuka rat; non A, non B CCK receptor; Otsuka Long Evans Tokushima Fatty rat; Type A CCK receptor; Type B CCK receptor

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; DEVAZEPIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH EMPTYING; STOMACH MOTILITY; STRAIN DIFFERENCE; VAGUS NERVE;

ANIMALS; BENZODIAZEPINONES; CHOLECYSTOKININ; DEVAZEPIDE; GASTROINTESTINAL MOTILITY; GLYCINE; MALE; NEURONS, AFFERENT; PHENYLUREA COMPOUNDS; RATS; RATS, INBRED STRAINS; RECEPTOR, CHOLECYSTOKININ A; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ; STOMACH; VAGUS NERVE;

EID: 0033555795     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(98)00175-1     Document Type: Article

References (27)

1. Dourish, C.T., Cooper, S.J., Iversen, S.D., Iversen, L.L., 1992. Multiple Cholecystokinin Receptors in the CNS. Oxford Univ. Press, Oxford.
2. Dourish C.T., Ruckert A.C., Tattersall F.D., Iversen S.D. Evidence that decreased feeding induced by systemic injection of cholecystokinin is mediated by CCK-A receptors. Eur. J. Pharmacol. 173:1989;233-234.
3. Funakoshi A., Miyasaka K., Jimi A., Kawanami T., Takata Y., Kono A. Little or no expression of the cholecystokinin-A receptor gene in the pancreas of diabetic rats (Otsuka Long-Evans Tokushima Fatty=OLETF rats). Biochem. Biophys. Res. Commun. 199:1994;482-488.
4. Funakoshi A., Miyasaka K., Shinozaki H., Masuda M., Kawanami T., Takata Y., Kono A. An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor. Biochem. Biophys. Res. Commun. 210:1995;787-796.
5. Funakoshi A., Miyasaka K., Kanai S., Masuda M., Yasunami Y., Nagai T., Ikeda S., Jimi A., Kawanami T., Kono A. Pancreatic endocrine dysfunction in rats not expressing the cholecystokinin-A receptor. Pancreas. 12:1996;230-236.
6. Funakoshi A., Miyasaka K., Shinozaki H., Arita Y., Nakano I., Nawara H. Regulation of pancreatic exocrine function in Otsuka Long-Evans Tokushima Fatty (OLETF) rats without gene expression of cholecystokinin-A receptor. Intern. Med. 35:1996;249-256.
7. Grundy D., Bagaev V., Hillsley K. Inhibition of gastric mechanoreceptor discharge by cholecystokinin in the rat. Am. J. Physiol. 268:1995;G355-G360.
8. Kawano K., Hirashima T., Mori S., Saitoh Y., Kurosumi M., Natori T. Spontaneous long-term hyperglycemic rat with diabetic complications: Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes. 41:1992;1422-1428.
9. Kawano K., Hirashima T., Mori S., Natori T. OLETF (Otsuka Long-Evans Tokushima Fatty) rat: a new NIDDM rat strain. Diabetes Res. Clin. Pract. 24:1994;S317-S320. Suppl.
10. Kurosawa M., Uvnäs-Moberg K., Miyasaka K., Lundeberg T. Interleukin-1 increases activity of the gastric vagal afferent nerve partly via stimulation of type A CCK receptor in anesthetized rats. J. Auton. Nerv. Syst. 62:1997;72-78.
11. -1 receptors are present on rabbit vagus nerve. Am. J. Physiol. 263:1992;R591-595.
12. Mercer J.G., Lawrence C.B. Selectivity of cholecystokinin (CCK) receptor antagonists, MK-329 and L-365,260, for axonally-transported CCK binding sites on the rat vagus nerve. Neurosci. Lett. 137:1992;229-231.
13. Miyasaka K., Kanai S., Ohta M., Jimi A., Kono A., Funakoshi A. Overexpression of cholecystokinin-B/gastrin receptor gene in the stomach of naturally occurring cholecystokinin-A receptor gene knockout rats. Digestion. 59:1998;26-32.
14. Miyasaka K., Kanai S., Ohta M., Kawanami T., Kono A., Funakoshi A. Lack of satiety effect of cholecystokinin (CCK) in a new rat model not expressing the CCK-A receptor gene. Neurosci. Lett. 180:1994;143-146.
15. Moran T.H., Ameglio P.J., Schwartz G.J., McHugh P.R. Blockade of type A, not type B, CCK receptors attenuates satiety actions of exogenous and endogenous CCK. Am. J. Physiol. 262:1992;R46-R50.
16. Moran T.H., Katz L.F., Plata-Salaman C.R., Schwartz G.J. Disordered food intake and obesity in rats lacking cholecystokinin A receptors. Am. J. Physiol. 274:1998;R618-R625.
17. B receptors expressed by vagal afferent neurons. Neuroscience. 79:1997;905-913.
18. Otsuki M., Akiyama T., Shirohara H., Nakano S., Furumi K., Tachibana I. Loss of sensitivity to cholecystokinin stimulation of isolated pancreatic acini from genetically diabetic rats. Am. J. Physiol. 268:1995;E531-E536.
19. Raybould H.E., Lloyd K.C.K. Integration of postprandial function in the proximal gastrointestinal tract: role of CCK and sensory pathways. Ann. NY Acad. Sci. 713:1994;143-156.
20. Schwartz G.J., McHugh P.R., Moran T.H. Pharmacological dissociation of responses to CCK and gastric loads in rat mechanosensitive vagal afferents. Am. J. Physiol. 267:1994;R303-R308.
21. Seva C., Dickinson C.J., Yamada T. Growth-promoting effects of glycine-extended progastrin. Science. 265:1994;410-412.
22. Shoji E., Okumura T., Onodera S., Takahashi N., Harada K., Kohgo Y. Gastric emptying in OLETF rats not expressing CCK-A receptor gene. Dig. Dis. Sci. 42:1997;915-919.
23. Singh P., Owlia A., Espeijo R., Dai B. Novel gastrin receptors mediate mitogenic effects of gastrin and processing intermediates of gastrin on Swiss 3T3 fibroblasts. J. Biol. Chem. 270:1995;8429-8438.
24. Smith G.P., Jerome C., Cushin B.J., Eterno R., Simansky K.J. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science. 213:1981;1036-1037.
25. Tachibana I., Akiyama T., Kanagawa K., Shiohara H., Furumi K., Watanabe N., Otsuki M. Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats. Am. J. Physiol. 270:1996;G730-G737.
26. Takiguchi S., Takata Y., Funakoshi A., Miyasaka K., Kataoka K., Fujimura Y., Goto T., Kono A. Disrupted cholecystokinin type-A receptor (CCKAR) gene in OLETF rats. Gene. 197:1997;169-175.
27. Wank S.A. Cholecystokinin receptors. Am. J. Physiol. 269:1995;G628-G646.