메뉴 건너뛰기




Volumn 78, Issue 1, 2005, Pages 289-300

Bcr-Abl regulates osteopontin transcription via Ras, PI-3K, aPKC, Raf-1, and MEK

Author keywords

Cellular signaling; Chronic myeloid leukemia; Gene expression

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BCR ABL PROTEIN; COMPLEMENTARY DNA; ETOPOSIDE; FARNESYLTHIOSALICYLIC ACID; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLSERINE; PROTEIN KINASE C; RAF PROTEIN; RAS PROTEIN; RNA; UO 126;

EID: 22144460122     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1104655     Document Type: Article
Times cited : (18)

References (66)
  • 1
    • 0018163889 scopus 로고
    • Chromosome abnormalities in the acute phase of CML
    • Rowley, J. D. (1978) Chromosome abnormalities in the acute phase of CML. Virchows Arch. B Cell Pathol. 29, 57-63.
    • (1978) Virchows Arch. B Cell Pathol. , vol.29 , pp. 57-63
    • Rowley, J.D.1
  • 2
    • 0021346853 scopus 로고
    • Philadelphia chromosomal breakpoints are clustered within a limited region, Bcr, on chromosome 22
    • Groffen, J., Stephenson, J. R., Heisterkamp, N., de Klein, A., Bartram, C. R., Grosveld, G. (1984) Philadelphia chromosomal breakpoints are clustered within a limited region, Bcr, on chromosome 22. Cell 36, 93-99.
    • (1984) Cell , vol.36 , pp. 93-99
    • Groffen, J.1    Stephenson, J.R.2    Heisterkamp, N.3    De Klein, A.4    Bartram, C.R.5    Grosveld, G.6
  • 3
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of Bcr-Abl oncogene products
    • Lugo, T. G., Pendergast, A. M., Muller, A. J., Witte, O. N. (1990) Tyrosine kinase activity and transformation potency of Bcr-Abl oncogene products. Science 247, 1079-1082.
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 4
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the P210Bcr/Abl gene of the Philadelphia chromosome
    • Daley, G. Q., Van Etten, R. A., Baltimore, D. (1990) Induction of chronic myelogenous leukemia in mice by the P210Bcr/Abl gene of the Philadelphia chromosome. Science 247, 824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 5
    • 0025187837 scopus 로고
    • Induction of a chronic myelogenous leukemia-like syndrome in mice with v-Abl and BCR/ABL
    • Kelliher, M. A., McLaughlin, J., Witte, O. N., Rosenberg, N. (1990) Induction of a chronic myelogenous leukemia-like syndrome in mice with v-Abl and BCR/ABL. Proc. Natl. Acad. Sci. USA 87, 6649-6653.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6649-6653
    • Kelliher, M.A.1    McLaughlin, J.2    Witte, O.N.3    Rosenberg, N.4
  • 6
    • 0022997481 scopus 로고
    • Alternative splicing of RNAs transcribed from the human Abl gene and from the Bcr-Abl fused gene
    • Shtivelman, E., Lifshitz, B., Gale, R. P., Roe, B. A., Canaani, E. (1986) Alternative splicing of RNAs transcribed from the human Abl gene and from the Bcr-Abl fused gene. Cell 47, 277-284.
    • (1986) Cell , vol.47 , pp. 277-284
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Roe, B.A.4    Canaani, E.5
  • 9
    • 0026808782 scopus 로고
    • BCR/ABL confers growth factor independence upon a murine myeloid cell line
    • Mandanas, R. A., Boswell, H. S., Lu, L., Leibowitz, D. (1992) BCR/ABL confers growth factor independence upon a murine myeloid cell line. Leukemia 6, 796-800.
    • (1992) Leukemia , vol.6 , pp. 796-800
    • Mandanas, R.A.1    Boswell, H.S.2    Lu, L.3    Leibowitz, D.4
  • 11
    • 0028256425 scopus 로고
    • Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia
    • Bedi, A., Zehnbauer, B. A., Barber, J. P., Sharkis, S. J., Jones, R. J. (1994) Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood 83, 2038-2044.
    • (1994) Blood , vol.83 , pp. 2038-2044
    • Bedi, A.1    Zehnbauer, B.A.2    Barber, J.P.3    Sharkis, S.J.4    Jones, R.J.5
  • 12
    • 0035199128 scopus 로고    scopus 로고
    • Elevated Bcr-Abl expression levels are sufficient for a haematopoietic cell line to acquire a drug-resistant phenotype
    • Keeshan, K., Mills, K. I., Cotter, T. G., McKenna, S. L. (2001) Elevated Bcr-Abl expression levels are sufficient for a haematopoietic cell line to acquire a drug-resistant phenotype. Leukemia 15, 1823-1833.
    • (2001) Leukemia , vol.15 , pp. 1823-1833
    • Keeshan, K.1    Mills, K.I.2    Cotter, T.G.3    McKenna, S.L.4
  • 14
    • 0035855648 scopus 로고    scopus 로고
    • Cooperative and redundant effects of STAT5 and Ras signaling in BCR/ABL transformed hematopoietic cells
    • Hoover, R. R., Gerlach, M. J., Koh, E. Y., Daley, G. Q. (2001) Cooperative and redundant effects of STAT5 and Ras signaling in BCR/ABL transformed hematopoietic cells. Oncogene 20, 5826-5835.
    • (2001) Oncogene , vol.20 , pp. 5826-5835
    • Hoover, R.R.1    Gerlach, M.J.2    Koh, E.Y.3    Daley, G.Q.4
  • 16
    • 0031573141 scopus 로고    scopus 로고
    • Constitutive activation of JAKs and STATs in BCR-ABL-expressing cell lines and peripheral blood cells derived from leukemic patients
    • Chai, S. K., Nichols, G. L., Rothman, P. (1997) Constitutive activation of JAKs and STATs in BCR-ABL-expressing cell lines and peripheral blood cells derived from leukemic patients. J. Immunol. 159, 4720-4728.
    • (1997) J. Immunol. , vol.159 , pp. 4720-4728
    • Chai, S.K.1    Nichols, G.L.2    Rothman, P.3
  • 17
    • 0028853560 scopus 로고
    • A biochemical characterization of the binding of osteopontin to integrins α v β 1 and α v β 5
    • Hu, D. D., Lin, E. C., Kovach, N. L., Hoyer, J. R., Smith, J. W. (1995) A biochemical characterization of the binding of osteopontin to integrins α v β 1 and α v β 5. J. Biol. Chem. 270, 26232-26238.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26232-26238
    • Hu, D.D.1    Lin, E.C.2    Kovach, N.L.3    Hoyer, J.R.4    Smith, J.W.5
  • 18
    • 0030064334 scopus 로고    scopus 로고
    • Receptor-ligand interaction between CD44 and osteopontin (η-1)
    • Weber, G. F., Ashkar, S., Glimcher, M. J., Cantor, H. (1996) Receptor-ligand interaction between CD44 and osteopontin (η-1). Science 271, 509-512.
    • (1996) Science , vol.271 , pp. 509-512
    • Weber, G.F.1    Ashkar, S.2    Glimcher, M.J.3    Cantor, H.4
  • 19
    • 0027522572 scopus 로고
    • Adhesion of metastatic, Ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin
    • Chambers, A. F., Hota, C., Prince, C. W. (1993) Adhesion of metastatic, Ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin. Cancer Res. 53, 701-706.
    • (1993) Cancer Res. , vol.53 , pp. 701-706
    • Chambers, A.F.1    Hota, C.2    Prince, C.W.3
  • 20
    • 0028228866 scopus 로고
    • Adhesive properties of osteopontin: Regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain
    • Senger, D. R., Perruzzi, C. A., Papadopoulos-Sergiou, A., Van de Water, L. (1994) Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain. Mol. Biol. Cell 5, 565-574.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 565-574
    • Senger, D.R.1    Perruzzi, C.A.2    Papadopoulos-Sergiou, A.3    Van De Water, L.4
  • 21
    • 0024780540 scopus 로고
    • The nature and significance of osteopontin
    • Butler, W. T. (1989) The nature and significance of osteopontin. Connect. Tissue Res. 23, 123-136.
    • (1989) Connect. Tissue Res. , vol.23 , pp. 123-136
    • Butler, W.T.1
  • 23
    • 0034778882 scopus 로고    scopus 로고
    • Expression, roles, receptors, and regulation of osteopontin in the kidney
    • Xie, Y., Sakatsume, M., Nishi, S., Narita, I., Arakawa, M., Gejyo, F. (2001) Expression, roles, receptors, and regulation of osteopontin in the kidney. Kidney Int. 60, 1645-1657.
    • (2001) Kidney Int. , vol.60 , pp. 1645-1657
    • Xie, Y.1    Sakatsume, M.2    Nishi, S.3    Narita, I.4    Arakawa, M.5    Gejyo, F.6
  • 25
    • 0023695494 scopus 로고
    • Secreted phosphoproteins associated with neoplastic transformation: Close homology with plasma proteins cleaved during blood coagulation
    • Senger, D. R., Perruzzi, C. A., Gracey, C. F., Papadopoulos, A., Tenen, D. G. (1988) Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation. Cancer Res. 48, 5770-5774.
    • (1988) Cancer Res. , vol.48 , pp. 5770-5774
    • Senger, D.R.1    Perruzzi, C.A.2    Gracey, C.F.3    Papadopoulos, A.4    Tenen, D.G.5
  • 26
    • 0033555721 scopus 로고    scopus 로고
    • PI 3-kinase γ and protein kinase C-ζ mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor
    • Takeda, H., Matozaki, T., Takada, T., Noguchi, T., Yamao, T., Tsuda, M., Ochi, F., Fukunaga, K., Inagaki, K., Kasuga, M. (1999) PI 3-kinase γ and protein kinase C-ζ mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor. EMBO J. 18, 386-395.
    • (1999) EMBO J. , vol.18 , pp. 386-395
    • Takeda, H.1    Matozaki, T.2    Takada, T.3    Noguchi, T.4    Yamao, T.5    Tsuda, M.6    Ochi, F.7    Fukunaga, K.8    Inagaki, K.9    Kasuga, M.10
  • 27
    • 0027476128 scopus 로고
    • Osteopontin overexpression is associated with arterial smooth muscle cell proliferation in vitro
    • Gadeau, A. P., Campan, M., Millet, D., Candresse, T., Desgranges, C. (1993) Osteopontin overexpression is associated with arterial smooth muscle cell proliferation in vitro. Arterioscler. Thromb. 13, 120-125.
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 120-125
    • Gadeau, A.P.1    Campan, M.2    Millet, D.3    Candresse, T.4    Desgranges, C.5
  • 29
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • Carroll, M., Ohno-Jones, S., Tamura, S., Buchdunger, E., Zimmermann, J., Lydon, N. B., Gilliland, D. G., Druker, B. J. (1997) CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood 90, 4947-4952.
    • (1997) Blood , vol.90 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3    Buchdunger, E.4    Zimmermann, J.5    Lydon, N.B.6    Gilliland, D.G.7    Druker, B.J.8
  • 30
    • 0026536323 scopus 로고
    • Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, Ras-transformed NIH 3T3 cells
    • Chambers, A. F., Behrend, E. I., Wilson, S. M., Denhardt, D. T. (1992) Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, Ras-transformed NIH 3T3 cells. Anticancer Res, 12, 43-47.
    • (1992) Anticancer Res , vol.12 , pp. 43-47
    • Chambers, A.F.1    Behrend, E.I.2    Wilson, S.M.3    Denhardt, D.T.4
  • 31
    • 18544372618 scopus 로고    scopus 로고
    • Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells
    • Sonoyama, J., Matsumura, I., Ezoe, S., Satoh, Y., Zhang, X., Kataoka, Y., Takai, E., Mizuki, M., Machii, T., Wakao, H., Kanakura, Y. (2002) Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells. J. Biol. Chem. 277, 8076-8082.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8076-8082
    • Sonoyama, J.1    Matsumura, I.2    Ezoe, S.3    Satoh, Y.4    Zhang, X.5    Kataoka, Y.6    Takai, E.7    Mizuki, M.8    Machii, T.9    Wakao, H.10    Kanakura, Y.11
  • 32
    • 0030471795 scopus 로고    scopus 로고
    • The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway
    • Cortez, D., Stoica, G., Pierce, J. H., Pendergast, A. M. (1996) The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway. Oncogene 13, 2589-2594.
    • (1996) Oncogene , vol.13 , pp. 2589-2594
    • Cortez, D.1    Stoica, G.2    Pierce, J.H.3    Pendergast, A.M.4
  • 33
    • 0142149155 scopus 로고    scopus 로고
    • Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent
    • Beck Jr., G. R., Knecht, N. (2003) Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent. J. Biol. Chem. 278, 41921-41929.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41921-41929
    • Beck Jr., G.R.1    Knecht, N.2
  • 37
    • 0037468265 scopus 로고    scopus 로고
    • Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways
    • Tuck, A. B., Hota, C., Wilson, S. M., Chambers, A. F. (2003) Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways. Oncogene 22, 1198-1205.
    • (2003) Oncogene , vol.22 , pp. 1198-1205
    • Tuck, A.B.1    Hota, C.2    Wilson, S.M.3    Chambers, A.F.4
  • 38
    • 0025101649 scopus 로고
    • Expression and properties of two distinct classes of the phorbol ester receptor family, four conventional protein kinase C types, and a novel protein kinase C
    • Akita, Y., Ohno, S., Konno, Y., Yano, A., Suzuki, K. (1990) Expression and properties of two distinct classes of the phorbol ester receptor family, four conventional protein kinase C types, and a novel protein kinase C. J. Biol. Chem. 265, 354-362.
    • (1990) J. Biol. Chem. , vol.265 , pp. 354-362
    • Akita, Y.1    Ohno, S.2    Konno, Y.3    Yano, A.4    Suzuki, K.5
  • 39
    • 0028881513 scopus 로고
    • Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase
    • Van Lint, J. V., Sinnett-Smith, J., Rozengurt, E. (1995) Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. J. Biol. Chem. 270, 1455-1461.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1455-1461
    • Van Lint, J.V.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 40
  • 41
    • 0028298476 scopus 로고
    • A new member of the third class in the protein kinase C family, PKC λ, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells
    • Akimoto, K., Mizuno, K., Osada, S., Hirai, S., Tanuma, S., Suzuki, K., Ohno, S. (1994) A new member of the third class in the protein kinase C family, PKC λ, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells. J. Biol. Chem. 269, 12677-12683.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12677-12683
    • Akimoto, K.1    Mizuno, K.2    Osada, S.3    Hirai, S.4    Tanuma, S.5    Suzuki, K.6    Ohno, S.7
  • 42
    • 0030808066 scopus 로고    scopus 로고
    • Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-ζ and Raf-1
    • van Dijk, M. C., Hilkmann, H., van Blitterswijk, W. J. (1997) Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-ζ and Raf-1. Biochem. J. 325, 303-307.
    • (1997) Biochem. J. , vol.325 , pp. 303-307
    • Van Dijk, M.C.1    Hilkmann, H.2    Van Blitterswijk, W.J.3
  • 43
    • 0030723178 scopus 로고    scopus 로고
    • Nucleolin is a protein kinase C-ζ substrate. Connection between cell surface signaling and nucleus in PC12 cells
    • Zhou, G., Seibenhener, M. L., Woolen, M. W. (1997) Nucleolin is a protein kinase C-ζ substrate. Connection between cell surface signaling and nucleus in PC12 cells. J. Biol. Chem. 272, 31130-31137.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31130-31137
    • Zhou, G.1    Seibenhener, M.L.2    Woolen, M.W.3
  • 44
    • 0023555557 scopus 로고
    • Protein kinase C contains a pseudosubstrate prototope in its regulatory domain
    • House, C., Kemp, B. E. (1987) Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 238, 1726-1728.
    • (1987) Science , vol.238 , pp. 1726-1728
    • House, C.1    Kemp, B.E.2
  • 45
    • 0027431089 scopus 로고
    • Molecular cloning and characterization of PKC ι, an atypical isoform of protein kinase C derived from insulin-secreting cells
    • Selbie, L. A., Schmitz-Peiffer, C., Sheng, Y., Biden, T. J. (1993) Molecular cloning and characterization of PKC ι, an atypical isoform of protein kinase C derived from insulin-secreting cells. J. Biol. Chem. 268, 24296-24302.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24296-24302
    • Selbie, L.A.1    Schmitz-Peiffer, C.2    Sheng, Y.3    Biden, T.J.4
  • 46
    • 0642376906 scopus 로고    scopus 로고
    • Protein kinase Cζ (PKCζ): Activation mechanisms and cellular functions
    • Hirai, T., Chida, K. (2003) Protein kinase Cζ (PKCζ): activation mechanisms and cellular functions. J. Biochem. (Tokyo) 133, 1-7.
    • (2003) J. Biochem. (Tokyo) , vol.133 , pp. 1-7
    • Hirai, T.1    Chida, K.2
  • 47
    • 0033959620 scopus 로고    scopus 로고
    • The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: Roles for phosphatidylinositol 3-kinase and Raf
    • Neshat, M. S., Raitano, A. B., Wang, H. G., Reed, J. C., Sawyers, C. L. (2000) The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf. MoL. Cell. Biol. 20, 1179-1186.
    • (2000) MoL. Cell. Biol. , vol.20 , pp. 1179-1186
    • Neshat, M.S.1    Raitano, A.B.2    Wang, H.G.3    Reed, J.C.4    Sawyers, C.L.5
  • 48
    • 0141462829 scopus 로고    scopus 로고
    • Elevated osteopontin and thrombospondin expression identifies malignant human breast carcinoma but is not indicative of metastatic status
    • Wang-Rodriguez, J., Urquidi, V., Rivard, A., Goodison, S. (2003) Elevated osteopontin and thrombospondin expression identifies malignant human breast carcinoma but is not indicative of metastatic status. Breast Cancer Res. 5, R136-R143.
    • (2003) Breast Cancer Res. , vol.5
    • Wang-Rodriguez, J.1    Urquidi, V.2    Rivard, A.3    Goodison, S.4
  • 49
    • 0036005977 scopus 로고    scopus 로고
    • Osteopontin modulates prostate carcinoma invasive capacity through RGD-dependent upregulation of plasminogen activators
    • Angelucci, A., Festuccia, C., D'AndrEa, G., Teti, A., Bologna, M. (2002) Osteopontin modulates prostate carcinoma invasive capacity through RGD-dependent upregulation of plasminogen activators. Biol. Chem. 383, 229-234.
    • (2002) Biol. Chem. , vol.383 , pp. 229-234
    • Angelucci, A.1    Festuccia, C.2    D'Andrea, G.3    Teti, A.4    Bologna, M.5
  • 54
    • 0037220080 scopus 로고    scopus 로고
    • Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter
    • Denhardt, D. T., Mistretta, D., Chambers, A. F., Krishna, S., Porter, J. F., Raghuram, S., Rittling, S. R. (2003) Transcriptional regulation of osteopontin and the metastatic phenotype: evidence for a Ras-activated enhancer in the human OPN promoter. Clin. Exp. Metastasis 20, 77-84.
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 77-84
    • Denhardt, D.T.1    Mistretta, D.2    Chambers, A.F.3    Krishna, S.4    Porter, J.F.5    Raghuram, S.6    Rittling, S.R.7
  • 55
    • 0031571094 scopus 로고    scopus 로고
    • Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation
    • Atkins, K. B., Simpson, R. U., Somerman, M. J. (1997) Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation. Arch. Biochem. Biophys. 343, 157-163.
    • (1997) Arch. Biochem. Biophys. , vol.343 , pp. 157-163
    • Atkins, K.B.1    Simpson, R.U.2    Somerman, M.J.3
  • 56
    • 0036257365 scopus 로고    scopus 로고
    • Novel protein kinase C isoforms and mitogen-activated kinase kinase mediate phorbol ester-induced osteopontin expression
    • Chang, P. L., Tucker, M. A., Hicks, P. H., Prince, C. W. (2002) Novel protein kinase C isoforms and mitogen-activated kinase kinase mediate phorbol ester-induced osteopontin expression. Int. J. Biochem. Cell Biol. 34, 1142-1151.
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 1142-1151
    • Chang, P.L.1    Tucker, M.A.2    Hicks, P.H.3    Prince, C.W.4
  • 57
    • 0035580983 scopus 로고    scopus 로고
    • Injury-induced osteopontin gene expression in rat arterial smooth muscle cells is dependent on mitogen-activated protein kinases ERK1/ERK2
    • Moses, S., Franzen, A., Lovdahl, C., Hultgardh-Nilsson, A. (2001) Injury-induced osteopontin gene expression in rat arterial smooth muscle cells is dependent on mitogen-activated protein kinases ERK1/ERK2. Arch. Biochem. Biophys. 396, 133-137.
    • (2001) Arch. Biochem. Biophys. , vol.396 , pp. 133-137
    • Moses, S.1    Franzen, A.2    Lovdahl, C.3    Hultgardh-Nilsson, A.4
  • 58
    • 0035018532 scopus 로고    scopus 로고
    • Regulation of angiotensin II-stimulated osteopontin expression in cardiac microvascular endothelial cells: Role of p42/44 mitogen-activated protein kinase and reactive oxygen species
    • Xie, Z., Pimental, D. R., Lohan, S., Vasertriger, A., Pligavko, C., Colucci, W. S., Singh, K. (2001) Regulation of angiotensin II-stimulated osteopontin expression in cardiac microvascular endothelial cells: role of p42/44 mitogen-activated protein kinase and reactive oxygen species. J. Cell. Physiol. 188, 132-138.
    • (2001) J. Cell. Physiol. , vol.188 , pp. 132-138
    • Xie, Z.1    Pimental, D.R.2    Lohan, S.3    Vasertriger, A.4    Pligavko, C.5    Colucci, W.S.6    Singh, K.7
  • 59
    • 0030836301 scopus 로고    scopus 로고
    • Atypical protein kinase C ι protects human leukemia cells against drug-induced apoptosis
    • Murray, N. R., Fields, A. P. (1997) Atypical protein kinase C ι protects human leukemia cells against drug-induced apoptosis. J. Biol. Chem. 272, 27521-27524.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27521-27524
    • Murray, N.R.1    Fields, A.P.2
  • 60
    • 0033547873 scopus 로고    scopus 로고
    • Protein kinase Cι activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis
    • Jamieson, L., Carpenter, L., Biden, T. J., Fields, A. P. (1999) Protein kinase Cι activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis. J. Biol. Chem. 274, 3927-3930.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3927-3930
    • Jamieson, L.1    Carpenter, L.2    Biden, T.J.3    Fields, A.P.4
  • 61
    • 1542334781 scopus 로고    scopus 로고
    • Bcr-Abl regulates protein kinase Cι (PKCι) transcription via an Elk1 site in the PKCι promoter
    • Gustafson, W. C., Ray, S., Jamieson, L., Thompson, E. A., Brasier, A. R., Fields, A. P. (2004) Bcr-Abl regulates protein kinase Cι (PKCι) transcription via an Elk1 site in the PKCι promoter. J. Biol. Chem. 279, 9400-9408.
    • (2004) J. Biol. Chem. , vol.279 , pp. 9400-9408
    • Gustafson, W.C.1    Ray, S.2    Jamieson, L.3    Thompson, E.A.4    Brasier, A.R.5    Fields, A.P.6
  • 65
    • 0035951830 scopus 로고    scopus 로고
    • Role of protein kinase Cζ in Ras-mediated transcriptional activation of vascular permeability factor/vascular endothelial growth factor expression
    • Pal, S., Datta, K., Khosravi-Far, R., Mukhopadhyay, D. (2001) Role of protein kinase Cζ in Ras-mediated transcriptional activation of vascular permeability factor/vascular endothelial growth factor expression. J. Biol. Chem. 276, 2395-2403.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2395-2403
    • Pal, S.1    Datta, K.2    Khosravi-Far, R.3    Mukhopadhyay, D.4
  • 66
    • 0036150235 scopus 로고    scopus 로고
    • Atypical protein kinase Cs are the Ras effectors that mediate repression of myogenic satellite cell differentiation
    • Fedorov, Y. V., Jones, N. C., Olwin, B. B. (2002) Atypical protein kinase Cs are the Ras effectors that mediate repression of myogenic satellite cell differentiation. Mol. Cell. Biol. 22, 1140-1149.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1140-1149
    • Fedorov, Y.V.1    Jones, N.C.2    Olwin, B.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.